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Des Moines

$248+ Cheap flights from Mexico to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
May 26 — Jun 21
Tue 5/26
Tue 6/2
1 adult, Economy
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Cheap flight deals from Mexico to Des Moines

Cheapest flights from Mexico to Des Moines
Explore the most affordable flight options available from Mexico to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 26, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:20 am
MEX
-
DSM
2 stops30h 11m
Multiple Airlines
Sun 6/78:36 pm
DSM
-
MEX
1 stop24h 29m
Multiple Airlines
Deal found 4/23$448
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:35 pm
GDL
-
DSM
2 stops40h 56m
Multiple Airlines
Mon 6/222:16 pm
DSM
-
GDL
1 stop27h 09m
Multiple Airlines
Deal found 4/23$455
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/810:45 pm
MEX
-
DSM
2 stops37h 46m
Multiple Airlines
Mon 6/159:56 pm
DSM
-
MEX
1 stop23h 09m
Multiple Airlines
Deal found 4/24$460
This Aeromexico deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:03 am
CUN
-
DSM
2 stops16h 29m
Aeromexico
Mon 5/255:27 am
DSM
-
CUN
1 stop6h 08m
Aeromexico
Deal found 4/21$480
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/251:43 pm
CUN
-
DSM
1 stop8h 52m
United Airlines
Mon 6/296:00 am
DSM
-
CUN
1 stop7h 10m
United Airlines
Deal found 4/24$517
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:22 pm
CUN
-
DSM
1 stop11h 05m
Multiple Airlines
Fri 6/122:16 pm
DSM
-
CUN
1 stop22h 32m
Multiple Airlines
Deal found 4/21$523
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:00 pm
MEX
-
DSM
2 stops15h 45m
Delta
Wed 7/295:25 am
DSM
-
MEX
2 stops10h 55m
Delta
Deal found 4/22$532
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:09 am
CUN
-
DSM
2 stops14h 23m
Delta
Fri 6/1211:28 am
DSM
-
CUN
1 stop8h 57m
Delta
Deal found 4/21$543
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:00 am
GDL
-
DSM
2 stops14h 00m
Multiple Airlines
Mon 8/312:16 pm
DSM
-
GDL
1 stop27h 09m
Multiple Airlines
Deal found 4/23$551
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:05 am
MEX
-
DSM
1 stop25h 37m
United Airlines
Mon 6/151:35 pm
DSM
-
MEX
1 stop8h 35m
United Airlines
Deal found 4/24$554
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:40 am
MEX
-
DSM
1 stop8h 02m
Delta
Thu 8/136:30 pm
DSM
-
MEX
2 stops14h 05m
Delta
Deal found 4/25$562
This CheapOair deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:02 am
GDL
-
DSM
2 stops29h 29m
Frontier
Mon 8/312:16 pm
DSM
-
GDL
2 stops24h 09m
Frontier
Deal found 4/23$570

Find flight deals from Mexico to Des Moines

Keep the following information in mind while searching for Mexico to Des Moines flight deals. Data was last updated April 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$448
(Kiwi.com)

One-way from

$248
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$680
Provider with most accurate pricing for Mexico City Benito Juarez-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Des Moines flights.
Search Deals
From Mexico to Des Moines
Search Deals
One-way flight from Mexico to Des Moines
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($24 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 26, 2026.
Use the filters below to find and compare flights from Mexico to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GuadalajaraDes Moines

GDL - DSM

GDLDSM

Guadalajara Miguel Hidal

Mon 6/8

7:35 pm-1:31 pm

2 stops40h 56m

Des Moines

Mon 6/22

2:16 pm-4:25 pm

1 stop27h 09m

$455

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 6/2

8:40 am-1:31 pm

1 stop27h 51m

Des Moines

Sun 6/7

8:36 pm-8:05 pm

1 stop24h 29m

$462

CancúnDes Moines

CUN - DSM

CUNDSM

Cancun

Thu 5/21

6:03 am-10:32 pm

2 stops16h 29m

Des Moines

Mon 5/25

5:27 am-11:35 am

1 stop6h 08m

$480

CancúnDes Moines

CUN - DSM

CUNDSM

Cancun

Thu 6/25

1:57 pm-10:35 pm

1 stop8h 38m

Des Moines

Mon 6/29

5:50 am-2:37 pm

2 stops8h 47m

$517

CancúnDes Moines

CUN - DSM

CUNDSM

Cancun

Fri 6/5

12:22 pm-11:27 pm

1 stop11h 05m

Des Moines

Fri 6/12

2:16 pm-12:48 pm

1 stop22h 32m

$523

CancúnDes Moines

CUN - DSM

CUNDSM

Cancun

Fri 6/5

8:09 am-10:32 pm

2 stops14h 23m

Des Moines

Fri 6/12

11:28 am-8:25 pm

1 stop8h 57m

$543

GuadalajaraDes Moines

GDL - DSM

GDLDSM

Guadalajara Miguel Hidal

Thu 8/20

6:00 am-9:00 pm

2 stops14h 00m

Des Moines

Mon 8/31

2:16 pm-4:25 pm

1 stop27h 09m

$551

GuadalajaraDes Moines

GDL - DSM

GDLDSM

Guadalajara Miguel Hidal

Thu 8/20

7:02 am-1:31 pm

2 stops29h 29m

Des Moines

Mon 8/31

2:16 pm-1:25 pm

2 stops24h 09m

$570

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 8/28

7:05 am-10:26 pm

1 stop14h 21m

Des Moines

Sun 8/30

7:00 am-3:30 pm

2 stops9h 30m

$593

Puerto VallartaDes Moines

PVR - DSM

PVRDSM

Puerto Vallarta Ordaz

Fri 8/28

12:19 pm-10:50 am

2 stops21h 31m

Des Moines

Tue 9/1

6:15 am-11:10 am

1 stop5h 55m

$594

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 43 resultsSorted by cheapest first
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Best time to book a flight from Mexico to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico to Des Moines

What is the cheapest month to book a flight from Mexico to Des Moines?

Currently, March is the cheapest month in which you can book a flight from Mexico to Des Moines (average of $476). Flying from Mexico to Des Moines in November is currently the most expensive (average of $611). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mexico to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Mexico?

    If you book a flight to Des Moines from Mexico, you will be flying to Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • How long is the flight from Mexico to Des Moines?

    Airlines like Aeromexico, United Airlines, and Frontier fly from Mexico to Des Moines in about 8h 38m. The time it takes to get you to your destination can typically vary by up to 20h 51m. The distance between Mexico and Des Moines is about 1470 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Mexico to Des Moines?

    The most popular flight routes from Mexico to Des Moines are Mexico City Benito Juarez - Des Moines, León Del Bajio - Des Moines and Guadalajara Miguel Hidal - Des Moines.

  • Can I find deals for flights from Mexico to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico to Des Moines.

  • Can I find deals for business class flights from Mexico to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico to Des Moines?

    Currently, March is the cheapest month in which you can book a flight from Mexico to Des Moines (average of $476). Flying from Mexico to Des Moines in November is currently the most expensive (average of $611). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny

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