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Des Moines

$218+ Cheap flights from Mexico to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
Aug 26 — Sep 21
Wed 8/26
Wed 9/2
1 adult, Economy
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Cheap flight deals from Mexico to Des Moines

Cheapest flights from Mexico to Des Moines
Explore the most affordable flight options available from Mexico to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.

This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:55 pm
PVR
-
DSM
1 stop25h 25m
United Airlines
Mon 10/56:00 am
DSM
-
PVR
1 stop6h 10m
United Airlines
Deal found 7/23$487
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:40 am
MEX
-
DSM
2 stops27h 28m
Multiple Airlines
Wed 9/302:42 pm
DSM
-
MEX
1 stop30h 23m
Multiple Airlines
Deal found 7/26$488
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:40 am
MEX
-
DSM
2 stops13h 10m
Multiple Airlines
Mon 11/22:51 pm
DSM
-
MEX
1 stop26h 09m
Multiple Airlines
Deal found 7/25$494
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1211:07 am
CUN
-
DSM
1 stop11h 36m
American Airlines
Sat 10/177:52 pm
DSM
-
CUN
1 stop18h 01m
American Airlines
Deal found 7/24$495
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/711:00 am
MEX
-
DSM
1 stop30h 42m
Multiple Airlines
Thu 10/158:43 am
DSM
-
MEX
2 stops36h 02m
Multiple Airlines
Deal found 7/23$542
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:51 am
CUN
-
DSM
2 stops15h 53m
United Airlines
Mon 8/171:35 pm
DSM
-
CUN
2 stops22h 27m
United Airlines
Deal found 7/23$549
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:40 am
MEX
-
DSM
1 stop27h 54m
Multiple Airlines
Sun 8/239:50 pm
DSM
-
MEX
2 stops32h 30m
Multiple Airlines
Deal found 7/24$550
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:00 am
CUN
-
DSM
1 stop7h 11m
American Airlines
Sat 10/177:52 pm
DSM
-
CUN
1 stop16h 08m
American Airlines
Deal found 7/24$551
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/239:15 am
MEX
-
DSM
2 stops10h 56m
Delta
Wed 9/3010:59 am
DSM
-
MEX
2 stops12h 21m
Delta
Deal found 7/26$551
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/294:40 am
MEX
-
DSM
2 stops11h 43m
United Airlines
Mon 11/29:13 am
DSM
-
MEX
1 stop13h 17m
United Airlines
Deal found 7/22$552
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:40 pm
GDL
-
DSM
1 stop6h 45m
United Airlines
Tue 11/171:35 pm
DSM
-
GDL
2 stops9h 00m
United Airlines
Deal found 7/23$555
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:40 am
GDL
-
DSM
2 stops15h 53m
United Airlines
Tue 9/296:00 am
DSM
-
GDL
1 stop6h 25m
United Airlines
Deal found 7/22$556

Find flight deals from Mexico to Des Moines

Keep the following information in mind while searching for Mexico to Des Moines flight deals. Data was last updated July 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$487
(United Airlines)

One-way from

$218
(OneTravel)

Popular in

November

Cheapest in

February

Average price

$553
Provider with most accurate pricing for Mexico City Benito Juarez-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Des Moines flights.
Search Deals
From Mexico to Des Moines
Search Deals
One-way flight from Mexico to Des Moines
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($89 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from Mexico to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Puerto VallartaDes Moines

PVR - DSM

PVRDSM

Puerto Vallarta Ordaz

Thu 10/1

1:55 pm-4:20 pm

1 stop25h 25m

Des Moines

Mon 10/5

6:00 am-11:10 am

1 stop6h 10m

$487

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 10/29

8:40 am-10:50 pm

2 stops13h 10m

Des Moines

Mon 11/2

2:51 pm-5:00 pm

1 stop26h 09m

$494

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 10/7

11:00 am-6:42 pm

1 stop30h 42m

Des Moines

Thu 10/15

8:43 am-7:45 pm

2 stops36h 02m

$542

CancúnDes Moines

CUN - DSM

CUNDSM

Cancun

Sat 8/15

7:51 am-11:44 pm

2 stops15h 53m

Des Moines

Mon 8/17

1:35 pm-12:02 pm

2 stops22h 27m

$549

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 10/29

6:50 am-2:20 pm

1 stop6h 30m

Des Moines

Mon 11/2

5:12 pm-2:15 pm

1 stop21h 03m

$549

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 9/23

9:15 am-9:11 pm

2 stops10h 56m

Des Moines

Wed 9/30

10:59 am-10:20 pm

2 stops12h 21m

$551

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 10/7

4:40 am-4:20 pm

2 stops10h 40m

Des Moines

Thu 10/15

5:45 am-5:50 pm

2 stops13h 05m

$551
Quickest round-trip

GuadalajaraDes Moines

GDL - DSM

GDLDSM

Guadalajara Miguel Hidal

Wed 11/11

3:40 pm-10:25 pm

1 stop6h 45m

Des Moines

Tue 11/17

1:35 pm-10:35 pm

2 stops9h 00m

$555

GuadalajaraDes Moines

GDL - DSM

GDLDSM

Guadalajara Miguel Hidal

Tue 9/22

8:27 am-10:26 pm

2 stops12h 59m

Des Moines

Tue 9/29

5:45 am-2:52 pm

2 stops10h 07m

$556

GuadalajaraDes Moines

GDL - DSM

GDLDSM

Guadalajara Miguel Hidal

Tue 9/22

6:40 am-11:33 pm

2 stops15h 53m

Des Moines

Tue 9/29

6:00 am-11:25 am

1 stop6h 25m

$556

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/24

Showing 1-10 of 52 resultsSorted by cheapest first
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Best time to book a flight from Mexico to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico to Des Moines

What is the cheapest month to book a flight from Mexico to Des Moines?

Currently, April is the cheapest month in which you can book a flight from Mexico to Des Moines (average of $525). Flying from Mexico to Des Moines in February is currently the most expensive (average of $997). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mexico to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Mexico?

    If you book a flight to Des Moines from Mexico, you will be flying to Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • How long is the flight from Mexico to Des Moines?

    Airlines like United Airlines, Delta, and Aeromexico fly from Mexico to Des Moines in about 10h 56m. The time it takes to get you to your destination can typically vary by up to 14h 29m. The distance between Mexico and Des Moines is about 1559 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Mexico to Des Moines?

    The most popular flight routes from Mexico to Des Moines are Mexico City Benito Juarez - Des Moines, León Del Bajio - Des Moines and Cancun - Des Moines.

  • Can I find deals for flights from Mexico to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico to Des Moines.

  • Can I find deals for business class flights from Mexico to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico to Des Moines?

    Currently, April is the cheapest month in which you can book a flight from Mexico to Des Moines (average of $525). Flying from Mexico to Des Moines in February is currently the most expensive (average of $997). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

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