Guadalajara

$172+ Cheap flights from Des Moines (DSM) to Guadalajara (GDL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GDL
Jul 8 — Jul 151
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Cheap flight deals from Des Moines to Guadalajara

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guadalajara (GDL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$367
(Mytrip)

One-way from

$172
(Mytrip)

Popular in

December

Cheapest in

September

Average price

$623
From Des Moines to Guadalajara Miguel Hidal
One-way flight from Des Moines to Guadalajara Miguel Hidal
Highest demand for flights based on searches. 12% potential increase in price ($93 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($30 potential savings vs. average RT price).
Average for round-trip flights in July 2025

Find flight deals from Des Moines to Guadalajara

Cheapest flights from Des Moines to Guadalajara
Explore the most affordable flight options available from Des Moines to Guadalajara. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Mytrip deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/174:00 pmDSM - GDL
2 stops22h 14mMultiple Airlines
Sun 8/249:05 pmGDL - DSM
2 stops24h 37mMultiple Airlines
Deal found 7/3$367
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/287:22 pmDSM - GDL
1 stop15h 28mAmerican Airlines
Tue 8/121:28 pmGDL - DSM
1 stop9h 46mAmerican Airlines
Deal found 7/2$544
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:15 amDSM - GDL
1 stop6h 10mUnited Airlines
Sun 10/512:30 pmGDL - DSM
1 stop8h 58mUnited Airlines
Deal found 7/2$564
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/157:00 amDSM - GDL
2 stops11h 58mDelta
Fri 8/229:17 amGDL - DSM
2 stops12h 22mDelta
Deal found 7/2$629

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Guadalajara that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Des Moines to Guadalajara that are best for you.

Fly from

Des Moines

Fly to

Guadalajara

Route

Depart

Return

Price

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 8/17

4:00 pm-1:14 pm

2 stops22h 14m

Guadalajara Miguel Hidal

Sun 8/24

9:05 pm-10:42 pm

2 stops24h 37m

$367

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Mon 7/28

7:22 pm-9:50 am

1 stop15h 28m

Guadalajara Miguel Hidal

Tue 8/12

1:28 pm-12:14 am

1 stop9h 46m

$544

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Thu 10/2

6:15 am-11:25 am

1 stop6h 10m

Guadalajara Miguel Hidal

Sun 10/5

12:30 pm-10:28 pm

1 stop8h 58m

$564

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 8/15

7:00 am-5:58 pm

2 stops11h 58m

Guadalajara Miguel Hidal

Fri 8/22

9:17 am-10:39 pm

2 stops12h 22m

$629

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 8/17

4:00 pm-1:14 pm

2 stops22h 14m

$172

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Wed 8/6

6:13 pm-12:48 pm

2 stops19h 35m

$293

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 8/17

6:50 pm-9:34 pm

2 stops27h 44m

$344

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Thu 7/17

5:30 am-5:47 pm

2 stops13h 17m

$353

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Des Moines to Guadalajara

Have a flexible travel schedule? Discover the best time to fly to Guadalajara from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guadalajara

What is the cheapest month to book a flight from Des Moines to Guadalajara?

Currently, February is the cheapest month in which you can book a flight from Des Moines to Guadalajara (average of $265). Flying from Des Moines to Guadalajara in December is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Guadalajara?

Reviews of airlines servicing Guadalajara

Get insights into the airlines that provide service to Guadalajara. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guadalajara. Reviews last updated July 3, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Des Moines to Guadalajara to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guadalajara. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines flying from Des Moines to Guadalajara round-trip?

    According to our current data, American Airlines ($544), United Airlines ($564), and Delta ($629) offers the cheapest pricing from Des Moines to Guadalajara. Users have found that American Airlines is 16% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Des Moines to Guadalajara one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $293. Delta flights start at $353 while deals on United Airlines start at $358 one-way.

  • Can I find deals for flights from Des Moines to Guadalajara that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guadalajara flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guadalajara?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guadalajara.

  • Can I find deals for business class flights from Des Moines to Guadalajara?

    Yes. Cheapflights offers flight deals from Des Moines to Guadalajara by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guadalajara?

    Currently, February is the cheapest month in which you can book a flight from Des Moines to Guadalajara (average of $265). Flying from Des Moines to Guadalajara in December is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Tlaquepaque
Zapopan

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Top 2 airlines flying from Des Moines to Guadalajara

Discover the top 2 airlines that operate flights from Des Moines to Guadalajara. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$502Average$622FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$521Average$715FlexibilityNo cancel feeOn-time69%

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