$247+ Cheap flights from Des Moines (DSM) to Guadalajara (GDL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/20. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GDL
Nov 20 — Nov 271
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Guadalajara with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Guadalajara
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Cheapest flights from Des Moines to GuadalajaraExplore the most affordable flight options available from Des Moines to Guadalajara. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 21, 2026.
Explore the most affordable flight options available from Des Moines to Guadalajara. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:35 pm -
2 stops27h 24m
Thu 12/102:07 pm -
1 stop19h 43m
Deal found 10/19![Multiple Airlines logo]()
$514
This Frontier deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:35 pm -
2 stops26h 10m
Thu 12/109:02 am -
1 stop10h 40m
Deal found 10/19![Frontier logo]()
$581
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:18 pm -
1 stop22h 43m
Wed 1/277:00 am -
2 stops38h 45m
Deal found 10/17![Multiple Airlines logo]()
$592
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:45 pm -
1 stop20h 43m
Thu 12/249:02 am -
1 stop10h 37m
Deal found 10/18![Multiple Airlines logo]()
$625
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:13 pm -
1 stop21h 34m
Mon 12/288:25 am -
2 stops28h 24m
Deal found 10/16![Multiple Airlines logo]()
$678
This Aeromexico deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:59 pm -
2 stops17h 37m
Tue 11/242:12 pm -
1 stop8h 23m
Deal found 10/19![Aeromexico logo]()
$685
Best flights from Des Moines to GuadalajaraDiscover carefully curated flight deals from Des Moines to Guadalajara that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 21, 2026.
Discover carefully curated flight deals from Des Moines to Guadalajara that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:18 pm -
1 stop22h 43m
Wed 1/2711:54 am -
1 stop29h 10m
Deal found 10/17![Multiple Airlines logo]()
$602
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/183:01 pm -
1 stop7h 34m
Wed 11/251:35 pm -
2 stops10h 07m
Deal found 10/21![United Airlines logo]()
$689
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:14 pm -
1 stop20h 34m
Sat 1/166:00 am -
1 stop11h 29m
Deal found 10/18![American Airlines logo]()
$758
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/63:00 pm -
1 stop7h 35m
Fri 1/155:45 am -
2 stops15h 38m
Deal found 10/20![United Airlines logo]()
$709
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/159:25 am -
2 stops13h 10m
Fri 1/295:45 am -
2 stops10h 26m
Deal found 10/18![United Airlines logo]()
$729
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/152:56 pm -
1 stop5h 54m
Tue 12/223:40 pm -
1 stop6h 49m
Deal found 10/18![United Airlines logo]()
$749
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/46:42 pm -
2 stops17h 54m
Sat 2/65:45 am -
2 stops15h 43m
Deal found 10/20![United Airlines logo]()
$839
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/16:00 am -
1 stop6h 36m
Fri 1/155:45 am -
2 stops15h 38m
Deal found 10/17![United Airlines logo]()
$846
Last-minute flights from Des Moines to GuadalajaraDiscover last-minute flight deals from Des Moines to Guadalajara. Data last updated October 21, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Guadalajara. Data last updated October 21, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:00 am -
1 stop30h 19m
Sun 10/2510:28 pm -
1 stop14h 31m
Deal found 10/20![Multiple Airlines logo]()
$702
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:33 am -
2 stops11h 01m
Sun 10/252:40 pm -
2 stops18h 52m
Deal found 10/20![United Airlines logo]()
$876
This Aeromexico deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:59 pm -
2 stops17h 37m
Tue 11/242:12 pm -
1 stop8h 23m
Deal found 10/19![Aeromexico logo]()
$685
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:01 pm -
1 stop7h 34m
Tue 11/245:45 am -
2 stops13h 31m
Deal found 10/19![United Airlines logo]()
$689
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:27 pm -
2 stops9h 08m
Wed 11/255:45 am -
2 stops11h 43m
Deal found 10/21![United Airlines logo]()
$780
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:10 am -
1 stop12h 49m
Mon 11/3010:27 am -
1 stop10h 22m
Deal found 10/17![Multiple Airlines logo]()
$761
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:00 am -
2 stops14h 35m
Mon 11/305:45 am -
2 stops39h 40m
Deal found 10/17![United Airlines logo]()
$843
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:16 pm -
1 stop16h 35m
Sat 12/56:00 am -
1 stop11h 52m
Deal found 10/21![American Airlines logo]()
$745
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/288:00 am -
2 stops14h 35m
Sat 12/58:00 am -
2 stops12h 33m
Deal found 10/21![United Airlines logo]()
$919
One-way flights from Des Moines to GuadalajaraSearch for one-way flight options from Des Moines to Guadalajara. Find affordable one-way fares based on user searches. Data last updated October 21, 2026.
Search for one-way flight options from Des Moines to Guadalajara. Find affordable one-way fares based on user searches. Data last updated October 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/209:31 pm -
2 stops26h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:39 pm -
2 stops27h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:18 pm -
2 stops34h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$286
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:00 am -
1 stop14h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![United Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/43:31 pm -
1 stop8h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![American Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:37 am -
1 stop13h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![American Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:30 am -
2 stops13h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![United Airlines logo]()
$401
Find flight deals from Des Moines to Guadalajara
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guadalajara (GDL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $514 (Kiwi.com) |
One-way from | $247 (Kiwi.com) |
Popular in | March |
Cheapest in | January |
Average price | $696 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Guadalajara that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 21, 2026.
Use the filters below to find and compare flights from Des Moines to Guadalajara that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Fri 12/4
9:18 pm-7:35 am
2 stops34h 17m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$286
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Thu 12/10
8:39 pm-11:15 pm
3 stops26h 36m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$310
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Tue 12/1
8:00 am-10:35 pm
1 stop14h 35m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$381
Quickest round-trip
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Fri 12/4
3:31 pm-11:50 pm
1 stop8h 19m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$391
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Fri 12/4
9:30 am-10:35 pm
2 stops13h 05m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$401
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Sat 11/28
7:16 pm-11:51 am
1 stop16h 35m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$426
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Wed 11/18
6:05 am-10:35 pm
2 stops16h 30m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$446
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Fri 11/20
9:31 pm-9:56 pm
3 stops24h 25m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$458
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Tue 12/1
1:58 pm-7:45 pm
3 stops29h 47m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$558
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Fri 12/4
9:18 pm-8:01 pm
1 stop22h 43m
Guadalajara Miguel Hidal
Wed 1/27
11:54 am-5:04 pm
1 stop29h 10m
$602
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Guadalajara
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Guadalajara in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Guadalajara flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Guadalajara flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Guadalajara flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Guadalajara flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Guadalajara flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Guadalajara
Have a flexible travel schedule? Discover the best time to fly to Guadalajara from Des Moines with our price prediction graph.
DSM-GDL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Guadalajara
What is the cheapest month to book a flight from Des Moines to Guadalajara?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Guadalajara (average of $583). Flying from Des Moines to Guadalajara in March is currently the most expensive (average of $993). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Guadalajara?
Airfare is below average for this route at the moment.
Des Moines to Guadalajara flights typically cost between $605 and $700 in December.The cheapest round-trip price found within the last 5 days was $514 on Multiple Airlines (Dec 3-Dec 10).
Reviews of airlines servicing Guadalajara
Get insights into the airlines that provide service to Guadalajara. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guadalajara. Reviews last updated October 21, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Des Moines to Guadalajara to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Boarding
7.7
Entertainment
7.1
Overall
7.3
Crew
8.1
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Comfort
7.3
Boarding
7.7
Entertainment
7.1
Overall
7.3
Crew
8.1
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Comfort
7.3
Boarding
7.7
Entertainment
7.1
Overall
7.3
Crew
8.1
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Guadalajara. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guadalajara?
Book flights to Guadalajara if you plan to visit one of these locationsTlaquepaque
Zapopan
Tequila
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Other flights to Guadalajara
Explore flights to Guadalajara departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 21, 2026.
Des Moines and Guadalajara flights
Browse other Des Moines and Guadalajara flight options. Last updated on October 21, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on October 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Guadalajara
Discover the top 2 airlines that operate flights from Des Moines to Guadalajara. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$560 | Average$739 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$566 | Average$763 | FlexibilityNo cancel fee | On-time69% |