$162+ Cheap flights from Des Moines (DSM) to Guadalajara (GDL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GDL
Oct 2 — Oct 91
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Guadalajara with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Guadalajara
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Cheapest flights from Des Moines to GuadalajaraExplore the most affordable flight options available from Des Moines to Guadalajara. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
Explore the most affordable flight options available from Des Moines to Guadalajara. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:09 pm -
1 stop24h 36m
Fri 11/69:45 am -
1 stop11h 50m
Deal found 9/2![Multiple Airlines logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:09 pm -
1 stop24h 36m
Thu 11/59:42 am -
1 stop9h 52m
Deal found 9/2![Multiple Airlines logo]()
$390
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:47 pm -
1 stop8h 58m
Fri 11/69:45 am -
1 stop11h 50m
Deal found 9/2![Multiple Airlines logo]()
$393
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:42 pm -
1 stop8h 03m
Fri 11/69:45 am -
1 stop11h 50m
Deal found 9/2![Multiple Airlines logo]()
$401
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:47 pm -
1 stop8h 58m
Thu 11/59:42 am -
1 stop9h 52m
Deal found 9/2![Multiple Airlines logo]()
$405
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:42 pm -
1 stop8h 03m
Thu 11/59:42 am -
1 stop9h 52m
Deal found 9/2![Multiple Airlines logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:56 pm -
1 stop19h 53m
Tue 9/2911:09 am -
2 stops25h 43m
Deal found 9/1![Multiple Airlines logo]()
$432
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:47 pm -
1 stop8h 58m
Tue 11/36:16 am -
2 stops31h 39m
Deal found 9/2![Multiple Airlines logo]()
$435
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:11 pm -
1 stop23h 43m
Mon 11/99:02 am -
1 stop10h 33m
Deal found 9/2![Multiple Airlines logo]()
$436
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:42 pm -
1 stop8h 03m
Thu 11/59:42 am -
1 stop9h 52m
Deal found 9/1![Multiple Airlines logo]()
$440
Best flights from Des Moines to GuadalajaraDiscover carefully curated flight deals from Des Moines to Guadalajara that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
Discover carefully curated flight deals from Des Moines to Guadalajara that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:42 pm -
1 stop8h 03m
Tue 10/206:10 am -
2 stops30h 42m
Deal found 8/28![Multiple Airlines logo]()
$512
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:00 am -
2 stops11h 35m
Tue 10/67:37 am -
2 stops13h 56m
Deal found 9/1![Delta logo]()
$645
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/41:23 pm -
2 stops9h 12m
Tue 12/151:35 pm -
1 stop8h 46m
Deal found 8/30![United Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:01 pm -
2 stops20h 29m
Wed 11/46:40 pm -
2 stops19h 45m
Deal found 9/2![Delta logo]()
$718
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:45 am -
2 stops8h 49m
Tue 10/2012:30 pm -
2 stops10h 18m
Deal found 8/29![United Airlines logo]()
$718
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:45 am -
1 stop6h 45m
Tue 9/296:00 pm -
2 stops15h 17m
Deal found 8/31![Delta logo]()
$750
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:55 pm -
2 stops19h 39m
Tue 10/206:40 am -
2 stops13h 21m
Deal found 8/28![United Airlines logo]()
$768
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:54 pm -
2 stops20h 51m
Wed 9/3010:26 am -
2 stops11h 00m
Deal found 8/31![Delta logo]()
$759
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:54 pm -
1 stop17h 36m
Wed 9/2312:55 pm -
1 stop8h 31m
Deal found 9/1![Delta logo]()
$761
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:54 pm -
1 stop17h 36m
Tue 9/227:36 am -
2 stops13h 50m
Deal found 9/1![Delta logo]()
$761
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:45 am -
1 stop6h 45m
Wed 9/2312:55 pm -
1 stop8h 31m
Deal found 9/1![Delta logo]()
$761
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:59 pm -
2 stops18h 31m
Mon 9/2112:55 pm -
2 stops20h 22m
Deal found 9/1![Delta logo]()
$765
Last-minute flights from Des Moines to GuadalajaraDiscover last-minute flight deals from Des Moines to Guadalajara. Data last updated September 2, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Guadalajara. Data last updated September 2, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:56 pm -
1 stop19h 53m
Tue 9/2911:09 am -
2 stops25h 43m
Deal found 9/1![Multiple Airlines logo]()
$432
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:42 pm -
1 stop8h 03m
Thu 11/59:42 am -
1 stop9h 52m
Deal found 9/1![Multiple Airlines logo]()
$440
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:09 pm -
1 stop24h 36m
Fri 11/69:45 am -
1 stop11h 50m
Deal found 9/2![Multiple Airlines logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:09 pm -
1 stop24h 36m
Thu 11/59:42 am -
1 stop9h 52m
Deal found 9/2![Multiple Airlines logo]()
$390
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:47 pm -
1 stop8h 58m
Fri 11/69:45 am -
1 stop11h 50m
Deal found 9/2![Multiple Airlines logo]()
$393
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:47 pm -
1 stop8h 58m
Thu 11/59:42 am -
1 stop9h 52m
Deal found 9/2![Multiple Airlines logo]()
$405
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:47 pm -
1 stop8h 58m
Tue 11/36:16 am -
2 stops31h 39m
Deal found 9/2![Multiple Airlines logo]()
$435
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:42 pm -
1 stop8h 03m
Fri 11/69:45 am -
1 stop11h 50m
Deal found 9/2![Multiple Airlines logo]()
$401
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:42 pm -
1 stop8h 03m
Thu 11/59:42 am -
1 stop9h 52m
Deal found 9/2![Multiple Airlines logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:11 pm -
1 stop23h 43m
Mon 11/99:02 am -
1 stop10h 33m
Deal found 9/2![Multiple Airlines logo]()
$436
One-way flights from Des Moines to GuadalajaraSearch for one-way flight options from Des Moines to Guadalajara. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
Search for one-way flight options from Des Moines to Guadalajara. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1010:07 pm -
1 stop21h 54m
Deal found 8/30![Multiple Airlines logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:31 pm -
1 stop20h 18m
Deal found 8/31![Multiple Airlines logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:25 pm -
1 stop19h 22m
Deal found 8/29![Multiple Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:00 am -
2 stops30h 01m
Deal found 9/1![Multiple Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:15 pm -
2 stops24h 05m
Deal found 8/29![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:31 pm -
3 stops45h 51m
Deal found 8/31![Multiple Airlines logo]()
$289
Find flight deals from Des Moines to Guadalajara
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guadalajara (GDL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $378 (Kiwi.com) |
One-way from | $162 (Kiwi.com) |
Popular in | March |
Cheapest in | November |
Average price | $832 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Guadalajara that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
Use the filters below to find and compare flights from Des Moines to Guadalajara that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Wed 10/14
2:42 pm-9:45 pm
1 stop8h 03m
Guadalajara Miguel Hidal
Tue 10/20
6:10 am-1:52 pm
2 stops30h 42m
$512
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Tue 9/29
7:00 am-5:35 pm
2 stops11h 35m
Guadalajara Miguel Hidal
Tue 10/6
7:37 am-10:33 pm
2 stops13h 56m
$645
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Fri 12/4
1:23 pm-10:35 pm
2 stops9h 12m
Guadalajara Miguel Hidal
Tue 12/15
1:35 pm-10:21 pm
1 stop8h 46m
$710
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Sat 10/24
4:01 pm-11:30 am
2 stops20h 29m
Guadalajara Miguel Hidal
Wed 11/4
6:40 pm-2:25 pm
2 stops19h 45m
$718
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Tue 10/13
5:45 am-1:34 pm
2 stops8h 49m
Guadalajara Miguel Hidal
Tue 10/20
12:30 pm-11:48 pm
2 stops10h 18m
$718
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Wed 9/16
5:45 am-11:30 am
1 stop6h 45m
Guadalajara Miguel Hidal
Tue 9/29
6:00 pm-10:17 am
2 stops15h 17m
$750
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Sun 9/13
6:54 pm-2:45 pm
2 stops20h 51m
Guadalajara Miguel Hidal
Wed 9/30
10:26 am-10:26 pm
2 stops11h 00m
$759
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Sun 9/13
6:54 pm-11:30 am
1 stop17h 36m
Guadalajara Miguel Hidal
Wed 9/23
12:55 pm-10:26 pm
1 stop8h 31m
$761
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Sun 9/13
6:54 pm-11:30 am
1 stop17h 36m
Guadalajara Miguel Hidal
Tue 9/22
7:36 am-10:26 pm
2 stops13h 50m
$761
Quickest round-trip
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Wed 9/16
5:45 am-11:30 am
1 stop6h 45m
Guadalajara Miguel Hidal
Wed 9/23
12:55 pm-10:26 pm
1 stop8h 31m
$761
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Guadalajara
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Guadalajara in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Guadalajara flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Guadalajara flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Guadalajara flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Guadalajara flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Guadalajara flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Guadalajara
Have a flexible travel schedule? Discover the best time to fly to Guadalajara from Des Moines with our price prediction graph.
DSM-GDL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Guadalajara
Reviews of airlines servicing Guadalajara
Get insights into the airlines that provide service to Guadalajara. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guadalajara. Reviews last updated September 2, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Des Moines to Guadalajara to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Entertainment
7.1
Food
6.6
Overall
7.4
Crew
8.1
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Boarding
7.7
Entertainment
7.1
Food
6.6
Overall
7.4
Crew
8.1
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Boarding
7.7
Entertainment
7.1
Food
6.6
Overall
7.4
Crew
8.1
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Guadalajara. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guadalajara?
Book flights to Guadalajara if you plan to visit one of these locationsTlaquepaque
Zapopan
Tequila
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Other flights to Guadalajara
Explore flights to Guadalajara departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 2, 2026.
Des Moines and Guadalajara flights
Browse other Des Moines and Guadalajara flight options. Last updated on September 2, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Guadalajara
Discover the top 2 airlines that operate flights from Des Moines to Guadalajara. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$545 | Average$737 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$566 | Average$769 | FlexibilityNo cancel fee | On-time69% |