$229+ Cheap flights from Des Moines (DSM) to Cancún (CUN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CUN
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Cancún with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Cancún
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Cheapest flights from Des Moines to CancúnExplore the most affordable flight options available from Des Moines to Cancún. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Des Moines to Cancún. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:37 pm -
1 stop14h 21m
Fri 11/134:00 pm -
1 stop17h 46m
Deal found 9/5![American Airlines logo]()
$562
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:06 am -
1 stop6h 19m
Wed 12/93:11 pm -
1 stop8h 54m
Deal found 9/6![American Airlines logo]()
$570
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:14 am -
1 stop13h 46m
Wed 10/281:00 pm -
1 stop19h 56m
Deal found 9/6![American Airlines logo]()
$572
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:36 am -
1 stop8h 19m
Wed 11/258:15 am -
2 stops13h 25m
Deal found 9/7![Delta logo]()
$575
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:07 am -
1 stop7h 03m
Wed 11/255:10 pm -
1 stop19h 31m
Deal found 9/9![American Airlines logo]()
$586
This Aeromexico deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:20 am -
1 stop14h 48m
Fri 12/1112:13 pm -
1 stop6h 53m
Deal found 9/5![Aeromexico logo]()
$589
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 am -
1 stop6h 37m
Mon 11/21:35 pm -
1 stop8h 01m
Deal found 9/8![United Airlines logo]()
$594
This Aeromexico deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:59 pm -
2 stops18h 25m
Tue 11/176:33 pm -
2 stops24h 34m
Deal found 9/9![Aeromexico logo]()
$595
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:45 am -
2 stops13h 10m
Tue 11/178:15 am -
2 stops12h 03m
Deal found 9/5![Delta logo]()
$599
Best flights from Des Moines to CancúnDiscover carefully curated flight deals from Des Moines to Cancún that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Des Moines to Cancún that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:36 am -
1 stop8h 19m
Wed 11/258:15 am -
2 stops13h 25m
Deal found 9/7![Delta logo]()
$575
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/165:20 am -
2 stops11h 05m
Mon 2/2212:10 pm -
2 stops11h 05m
Deal found 9/8![Southwest logo]()
$641
This Aeromexico deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:35 am -
1 stop14h 20m
Thu 10/299:24 am -
2 stops13h 09m
Deal found 9/9![Aeromexico logo]()
$660
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:35 am -
1 stop8h 33m
Fri 12/119:24 am -
2 stops14h 14m
Deal found 9/8![Delta logo]()
$595
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/187:00 am -
1 stop6h 10m
Sun 1/244:30 pm -
1 stop6h 59m
Deal found 9/9![Delta logo]()
$595
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:35 am -
2 stops9h 15m
Mon 10/2611:00 am -
2 stops12h 15m
Deal found 9/6![Southwest logo]()
$674
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/235:45 am -
2 stops13h 15m
Wed 1/271:55 pm -
1 stop8h 29m
Deal found 9/5![Delta logo]()
$595
Last-minute flights from Des Moines to CancúnDiscover last-minute flight deals from Des Moines to Cancún. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Cancún. Data last updated September 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:14 pm -
2 stops18h 19m
Wed 10/712:00 pm -
1 stop11h 07m
Deal found 9/5![American Airlines logo]()
$600
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:14 am -
1 stop13h 46m
Wed 10/281:00 pm -
1 stop19h 56m
Deal found 9/6![American Airlines logo]()
$572
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:00 am -
1 stop8h 37m
Wed 10/281:55 pm -
1 stop8h 00m
Deal found 9/8![United Airlines logo]()
$602
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:42 pm -
1 stop15h 12m
Thu 10/291:00 pm -
1 stop11h 14m
Deal found 9/7![American Airlines logo]()
$620
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:42 pm -
1 stop14h 15m
Tue 10/277:20 am -
1 stop15h 47m
Deal found 9/5![American Airlines logo]()
$562
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:42 pm -
2 stops14h 51m
Wed 10/281:00 pm -
1 stop11h 14m
Deal found 9/5![American Airlines logo]()
$567
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 am -
1 stop6h 37m
Mon 11/21:35 pm -
1 stop8h 01m
Deal found 9/8![United Airlines logo]()
$594
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:35 am -
2 stops9h 15m
Sun 11/111:20 am -
2 stops12h 40m
Deal found 9/6![Southwest logo]()
$611
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:35 am -
2 stops9h 15m
Mon 11/22:35 pm -
2 stops9h 25m
Deal found 9/8![Southwest logo]()
$630
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:14 am -
1 stop13h 47m
Thu 11/54:35 pm -
1 stop7h 30m
Deal found 9/5![American Airlines logo]()
$595
One-way flights from Des Moines to CancúnSearch for one-way flight options from Des Moines to Cancún. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Des Moines to Cancún. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/317:45 am -
2 stops15h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:54 pm -
2 stops20h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:25 pm -
2 stops27h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:35 pm -
2 stops25h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:42 pm -
2 stops31h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/17:30 am -
2 stops25h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:42 pm -
2 stops43h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$269
Find flight deals from Des Moines to Cancún
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Cancún (CUN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $562 (American Airlines) |
One-way from | $229 (Kiwi.com) |
Popular in | November |
Cheapest in | September |
Average price | $466 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Cancún that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Des Moines to Cancún that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Mon 2/1
7:30 am-9:41 am
2 stops25h 11m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$259
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Sat 10/24
7:42 pm-10:54 am
1 stop15h 12m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$275
Quickest round-trip
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Sun 1/31
7:00 am-3:20 pm
1 stop7h 20m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$276
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Wed 11/18
7:28 am-8:55 pm
2 stops12h 27m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$276
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Wed 11/18
6:00 am-5:00 pm
2 stops10h 00m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$276
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Wed 11/18
11:36 am-8:55 pm
1 stop8h 19m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$276
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Sun 10/18
6:00 am-7:55 pm
2 stops13h 55m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$276
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Mon 2/1
9:45 am-9:18 pm
1 stop10h 33m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$276
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Mon 2/1
5:45 am-4:30 pm
1 stop9h 45m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$276
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Tue 10/20
5:35 am-2:50 pm
2 stops9h 15m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$287
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Cancún
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Cancún in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Cancún flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Cancún flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Cancún flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Cancún flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Cancún flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Cancún
Have a flexible travel schedule? Discover the best time to fly to Cancún from Des Moines with our price prediction graph.
DSM-CUN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Cancún
How far ahead should I book a flight from Des Moines to Cancún?
The best time to book flights from Des Moines to Cancún is 21 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Des Moines to Cancún?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Cancún (average of $466). Flying from Des Moines to Cancún in November is currently the most expensive (average of $802). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Cancún
Get insights into the airlines that provide service to Cancún. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cancún. Reviews last updated September 10, 2026.
Read through reviews of airlines operating flights from Des Moines to Cancún, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Cancún. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Cancún?
Book flights to Cancún if you plan to visit one of these locationsPuerto Aventuras
Punta Sam
Holbox
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Other flights to Cancún
Explore flights to Cancún departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Complete your trip
Complete your trip to Cancún by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Des Moines to Cancún, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Cancún flights
Browse other Des Moines and Cancún flight options. Last updated on September 10, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from Des Moines to Cancún
Discover the top 5 airlines that operate flights from Des Moines to Cancún. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$229 | Average$494 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$465 | Average$755 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$466 | Average$626 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$473 | Average$644 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$569 | Average$700 | FlexibilityNo cancel fee | On-time63% |