$256+ Cheap flights from Des Moines to McAllen (DSM - MFE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/30. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MFE
Jul 17 — Jul 241
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to McAllen with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to McAllen
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Best
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Cheapest flights from Des Moines to McAllenExplore the most affordable flight options available from Des Moines to McAllen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 17, 2026.
Explore the most affordable flight options available from Des Moines to McAllen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 17, 2026.
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:30 am
DSM
- MFE
1 stop4h 29m
American Airlines
Tue 7/79:23 am
MFE
- DSM
1 stop6h 37m
American Airlines
Deal found 6/16![American Airlines logo]()
$315
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:12 am
DSM
- MFE
1 stop4h 45m
American Airlines
Tue 7/1410:37 am
MFE
- DSM
1 stop5h 23m
American Airlines
Deal found 6/13![American Airlines logo]()
$352
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:48 pm
DSM
- MFE
1 stop4h 58m
American Airlines
Tue 7/79:23 am
MFE
- DSM
1 stop6h 37m
American Airlines
Deal found 6/16![American Airlines logo]()
$357
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:48 pm
DSM
- MFE
1 stop7h 27m
American Airlines
Tue 8/189:19 am
MFE
- DSM
1 stop5h 53m
American Airlines
Deal found 6/16![American Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:30 am
DSM
- MFE
1 stop4h 29m
American Airlines
Tue 7/1410:37 am
MFE
- DSM
1 stop5h 23m
American Airlines
Deal found 6/16![American Airlines logo]()
$405
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:20 am
DSM
- MFE
1 stop5h 05m
United Airlines
Wed 8/195:19 am
MFE
- DSM
2 stops8h 57m
United Airlines
Deal found 6/16![United Airlines logo]()
$412
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:02 pm
DSM
- MFE
1 stop5h 16m
American Airlines
Sat 7/189:23 am
MFE
- DSM
1 stop6h 37m
American Airlines
Deal found 6/16![American Airlines logo]()
$425
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/287:02 pm
DSM
- MFE
1 stop5h 16m
American Airlines
Fri 7/310:37 am
MFE
- DSM
1 stop5h 23m
American Airlines
Deal found 6/13![American Airlines logo]()
$427
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:13 pm
DSM
- MFE
1 stop5h 02m
American Airlines
Sat 8/154:18 pm
MFE
- DSM
2 stops8h 17m
American Airlines
Deal found 6/16![American Airlines logo]()
$430
Best flights from Des Moines to McAllenDiscover carefully curated flight deals from Des Moines to McAllen that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 17, 2026.
Discover carefully curated flight deals from Des Moines to McAllen that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 17, 2026.
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:48 pm
DSM
- MFE
1 stop4h 58m
American Airlines
Thu 7/1610:37 am
MFE
- DSM
1 stop5h 23m
American Airlines
Deal found 6/12![American Airlines logo]()
$448
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:00 am
DSM
- MFE
2 stops11h 00m
United Airlines
Tue 12/87:27 pm
MFE
- DSM
2 stops14h 53m
United Airlines
Deal found 6/16![United Airlines logo]()
$538
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/72:25 pm
DSM
- MFE
2 stops9h 34m
Delta
Mon 7/1312:35 pm
MFE
- DSM
2 stops9h 54m
Delta
Deal found 6/12![Delta logo]()
$539
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:01 pm
DSM
- MFE
1 stop18h 03m
Multiple Airlines
Sun 7/129:59 pm
MFE
- DSM
2 stops24h 31m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$545
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/99:23 am
DSM
- MFE
1 stop22h 30m
Multiple Airlines
Thu 7/168:44 pm
MFE
- DSM
2 stops25h 46m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$583
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:00 am
DSM
- MFE
2 stops8h 05m
United Airlines
Sun 11/17:15 am
MFE
- DSM
2 stops17h 25m
United Airlines
Deal found 6/14![United Airlines logo]()
$597
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:55 am
DSM
- MFE
2 stops9h 42m
Delta
Fri 8/215:20 am
MFE
- DSM
2 stops11h 30m
Delta
Deal found 6/16![Delta logo]()
$609
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/72:25 pm
DSM
- MFE
2 stops9h 34m
Delta
Tue 7/1412:35 pm
MFE
- DSM
2 stops9h 54m
Delta
Deal found 6/14![Delta logo]()
$609
Last-minute flights from Des Moines to McAllenDiscover last-minute flight deals from Des Moines to McAllen. Data last updated June 17, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to McAllen. Data last updated June 17, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:02 pm
DSM
- MFE
1 stop5h 16m
American Airlines
Wed 6/241:35 pm
MFE
- DSM
1 stop4h 47m
American Airlines
Deal found 6/12![American Airlines logo]()
$451
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/287:02 pm
DSM
- MFE
1 stop5h 16m
American Airlines
Fri 7/310:37 am
MFE
- DSM
1 stop5h 23m
American Airlines
Deal found 6/13![American Airlines logo]()
$427
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:30 am
DSM
- MFE
1 stop4h 29m
American Airlines
Tue 7/1410:37 am
MFE
- DSM
1 stop5h 23m
American Airlines
Deal found 6/16![American Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:02 pm
DSM
- MFE
1 stop5h 16m
American Airlines
Sat 7/189:23 am
MFE
- DSM
1 stop6h 37m
American Airlines
Deal found 6/16![American Airlines logo]()
$425
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:30 am
DSM
- MFE
1 stop4h 29m
American Airlines
Tue 7/79:23 am
MFE
- DSM
1 stop6h 37m
American Airlines
Deal found 6/16![American Airlines logo]()
$315
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:23 am
DSM
- MFE
1 stop4h 34m
American Airlines
Tue 7/1410:37 am
MFE
- DSM
1 stop5h 23m
American Airlines
Deal found 6/16![American Airlines logo]()
$447
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:48 pm
DSM
- MFE
1 stop4h 58m
American Airlines
Tue 7/79:23 am
MFE
- DSM
1 stop6h 37m
American Airlines
Deal found 6/16![American Airlines logo]()
$357
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:12 am
DSM
- MFE
1 stop4h 45m
American Airlines
Tue 7/1410:37 am
MFE
- DSM
1 stop5h 23m
American Airlines
Deal found 6/13![American Airlines logo]()
$352
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:12 am
DSM
- MFE
1 stop4h 45m
American Airlines
Mon 7/135:25 pm
MFE
- DSM
1 stop6h 33m
American Airlines
Deal found 6/12![American Airlines logo]()
$448
One-way flights from Des Moines to McAllenSearch for one-way flight options from Des Moines to McAllen. Find affordable one-way fares based on user searches. Data last updated June 17, 2026.
Search for one-way flight options from Des Moines to McAllen. Find affordable one-way fares based on user searches. Data last updated June 17, 2026.
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:35 am
DSM
- MFE
2 stops10h 48m
Delta
Deal found 6/16![Delta logo]()
$256
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:42 am
DSM
- MFE
2 stops11h 16m
Delta
Deal found 6/16![Delta logo]()
$305
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/304:48 pm
DSM
- MFE
1 stop7h 30m
American Airlines
Deal found 6/16![American Airlines logo]()
$313
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:23 am
DSM
- MFE
1 stop4h 34m
American Airlines
Deal found 6/16![American Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:20 am
DSM
- MFE
1 stop5h 05m
United Airlines
Deal found 6/16![United Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/295:35 am
DSM
- MFE
2 stops10h 48m
Delta
Deal found 6/16![Delta logo]()
$394
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/285:00 am
DSM
- MFE
2 stops11h 55m
American Airlines
Deal found 6/16![American Airlines logo]()
$497
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:00 am
DSM
- MFE
3 stops15h 51m
United Airlines
Deal found 6/16![United Airlines logo]()
$688
Find flight deals from Des Moines to McAllen
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to McAllen (MFE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $315 (American Airlines) |
One-way from | $256 (Delta) |
Popular in | May |
Cheapest in | September |
Average price | $384 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to McAllen that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 17, 2026.
Use the filters below to find and compare flights from Des Moines to McAllen that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Des MoinesMcAllen
DSM - MFE
DSMMFE
Des Moines
Thu 7/9
4:48 pm-9:46 pm
1 stop4h 58m
McAllen Miller Intl
Thu 7/16
10:37 am-4:00 pm
1 stop5h 23m
$448
Des MoinesMcAllen
DSM - MFE
DSMMFE
Des Moines
Sat 12/5
5:00 am-4:00 pm
2 stops11h 00m
McAllen Miller Intl
Tue 12/8
7:27 pm-10:20 am
2 stops14h 53m
$538
Des MoinesMcAllen
DSM - MFE
DSMMFE
Des Moines
Tue 7/7
2:25 pm-11:59 pm
2 stops9h 34m
McAllen Miller Intl
Mon 7/13
12:35 pm-10:29 pm
2 stops9h 54m
$539
Des MoinesMcAllen
DSM - MFE
DSMMFE
Des Moines
Mon 7/6
10:01 pm-4:04 pm
1 stop18h 03m
McAllen Miller Intl
Sun 7/12
9:59 pm-10:30 pm
2 stops24h 31m
$545
Des MoinesMcAllen
DSM - MFE
DSMMFE
Des Moines
Thu 7/9
9:23 am-7:53 am
1 stop22h 30m
McAllen Miller Intl
Thu 7/16
8:44 pm-10:30 pm
2 stops25h 46m
$583
Des MoinesMcAllen
DSM - MFE
DSMMFE
Des Moines
Thu 10/29
5:00 am-1:05 pm
2 stops8h 05m
McAllen Miller Intl
Sun 11/1
7:15 am-12:40 am
2 stops17h 25m
$597
Des MoinesMcAllen
DSM - MFE
DSMMFE
Des Moines
Fri 8/7
6:55 am-4:37 pm
2 stops9h 42m
McAllen Miller Intl
Fri 8/21
5:20 am-4:50 pm
2 stops11h 30m
$609
Des MoinesMcAllen
DSM - MFE
DSMMFE
Des Moines
Tue 7/7
2:25 pm-11:59 pm
2 stops9h 34m
McAllen Miller Intl
Tue 7/14
12:35 pm-10:29 pm
2 stops9h 54m
$609
Cheapest one-way
Des MoinesMcAllen
DSM - MFE
DSMMFE
Des Moines
Tue 6/30
5:35 am-4:23 pm
2 stops10h 48m
$256
Des MoinesMcAllen
DSM - MFE
DSMMFE
Des Moines
Fri 7/3
11:42 am-10:58 pm
2 stops11h 16m
$305
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Des Moines to McAllen
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to McAllen in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-McAllen flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-McAllen flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-McAllen flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-McAllen flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-McAllen flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to McAllen
Have a flexible travel schedule? Discover the best time to fly to McAllen from Des Moines with our price prediction graph.
DSM-MFE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing McAllen
Get insights into the airlines that provide service to McAllen. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to McAllen. Reviews last updated June 17, 2026.
Read through reviews of airlines operating flights from Des Moines to McAllen, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Crew
8.1
Food
6.6
Comfort
7.3
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Boarding
7.7
Crew
8.1
Food
6.6
Comfort
7.3
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Boarding
7.7
Crew
8.1
Food
6.6
Comfort
7.3
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Related info for your journey
Find useful and relevant information for your journey from Des Moines to McAllen. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near McAllen?
Book flights to McAllen if you plan to visit one of these locationsPharr
Weslaco
Mission
Edinburg
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Other flights to McAllen
Explore flights to McAllen departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 17, 2026.
Des Moines and McAllen flights
Browse other Des Moines and McAllen flight options. Last updated on June 17, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on June 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to McAllen
Discover the top 2 airlines that operate flights from Des Moines to McAllen. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$404 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$283 | Average$315 | FlexibilityNo cancel fee | On-time69% |