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$164+ Cheap flights from Des Moines to Medford (DSM - MFR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MFR
May 23 — May 301
Sat 5/23
Sat 5/30
1 adult, Economy
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Cheap flight deals from Des Moines to Medford

Cheapest flights from Des Moines to Medford
Explore the most affordable flight options available from Des Moines to Medford. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:56 pm
DSM
-
MFR
1 stop12h 36m
Allegiant Air
Thu 9/179:22 am
MFR
-
DSM
1 stop9h 44m
Allegiant Air
Deal found 4/22$350
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:26 pm
DSM
-
MFR
1 stop6h 38m
American Airlines
Sat 5/22:08 pm
MFR
-
DSM
1 stop7h 48m
American Airlines
Deal found 4/18$444
This Expedia deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:13 pm
DSM
-
MFR
2 stops19h 39m
Alaska Airlines
Thu 9/177:00 am
MFR
-
DSM
2 stops14h 07m
Alaska Airlines
Deal found 4/22$459
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:00 am
DSM
-
MFR
2 stops24h 32m
Multiple Airlines
Thu 9/179:22 am
MFR
-
DSM
1 stop9h 44m
Multiple Airlines
Deal found 4/22$468
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:26 pm
DSM
-
MFR
1 stop6h 38m
American Airlines
Sat 5/22:08 pm
MFR
-
DSM
1 stop7h 48m
American Airlines
Deal found 4/18$474
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:45 am
DSM
-
MFR
1 stop9h 05m
American Airlines
Sat 7/111:23 pm
MFR
-
DSM
1 stop8h 25m
American Airlines
Deal found 4/22$478
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:23 pm
DSM
-
MFR
2 stops8h 57m
Delta
Sat 5/25:10 am
MFR
-
DSM
2 stops9h 52m
Delta
Deal found 4/18$484
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:36 pm
DSM
-
MFR
1 stop20h 13m
Multiple Airlines
Sun 6/219:31 pm
MFR
-
DSM
2 stops23h 22m
Multiple Airlines
Deal found 4/21$493
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:36 pm
DSM
-
MFR
1 stop20h 13m
Allegiant Air
Sun 6/219:31 pm
MFR
-
DSM
1 stop21h 35m
Allegiant Air
Deal found 4/21$503

Find flight deals from Des Moines to Medford

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Medford (MFR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$350
(Kiwi.com)

One-way from

$212
(Kiwi.com)

Popular in

February

Cheapest in

December

Average price

$393
Provider with most accurate pricing for Des Moines-Medford flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Medford flights.
Search Deals
From Des Moines to Medford
Search Deals
One-way flight from Des Moines to Medford
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($150 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 11% potential price decrease ($48 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Des Moines to Medford that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Thu 9/10

10:00 am-8:32 am

2 stops24h 32m

Medford

Thu 9/17

9:22 am-9:06 pm

1 stop9h 44m

$468

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Thu 6/18

8:36 pm-2:49 pm

1 stop20h 13m

Medford

Sun 6/21

9:31 pm-9:06 pm

1 stop21h 35m

$503

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Sun 5/24

5:00 am-12:49 pm

2 stops9h 49m

Medford

Fri 5/29

7:16 pm-6:36 pm

2 stops21h 20m

$577

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Sun 5/24

5:17 pm-9:16 pm

1 stop5h 59m

Medford

Fri 5/29

6:35 pm-12:47 pm

2 stops16h 12m

$594

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Thu 7/30

5:50 am-12:04 pm

2 stops8h 14m

Medford

Tue 8/4

6:35 pm-10:27 am

2 stops13h 52m

$599
Quickest round-trip

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Sat 6/27

5:17 pm-9:17 pm

1 stop6h 00m

Medford

Sat 7/4

6:00 am-4:15 pm

2 stops8h 15m

$604

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Mon 6/15

5:45 am-7:13 pm

2 stops15h 28m

Medford

Sun 6/21

12:30 pm-8:12 am

2 stops17h 42m

$615

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Wed 7/1

11:23 am-10:59 pm

2 stops13h 36m

Medford

Sat 7/11

6:00 am-4:15 pm

2 stops8h 15m

$640
Cheapest one-way

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Thu 9/10

9:56 pm-8:32 am

1 stop12h 36m

$169

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Thu 9/3

9:56 pm-8:45 pm

1 stop24h 49m

$200

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Compare providers for flights from Des Moines to Medford

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Medford in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Medford flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Medford flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Medford flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Medford flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Medford flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Medford

Have a flexible travel schedule? Discover the best time to fly to Medford from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Medford

How much does it cost to fly round-trip from Des Moines to Medford?

Reviews of airlines servicing Medford

Get insights into the airlines that provide service to Medford. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medford. Reviews last updated April 23, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Des Moines to Medford by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,637 reviews

Overall

7.4

Crew

8.1

Food

6.6

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.
United Airlines
7.4
Good
9,637 reviews
United Airlines
7.4
Good
9,637 reviews

Overall

7.4

Crew

8.1

Food

6.6

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.
American Airlines
7.1
Good
11,659 reviews
United Airlines
7.4
Good
9,637 reviews

Overall

7.4

Crew

8.1

Food

6.6

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Medford. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Medford?

    Airlines like Allegiant Air and Alaska Airlines fly from Des Moines to Medford in about 9h 49m. The time it takes to get you to your destination can typically vary by up to 10h 24m. Des Moines and Medford are separated by a distance of 1494 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Des Moines to Medford round-trip?

    According to our current data, United Airlines ($274), and American Airlines ($328) offers the cheapest pricing from Des Moines to Medford. United Airlines is 41% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Des Moines to Medford that include hotel bookings?

    Yes. In addition to deals on Des Moines to Medford flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Medford?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Medford.

  • Can I find deals for business class flights from Des Moines to Medford?

    Yes. Cheapflights offers flight deals from Des Moines to Medford by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
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Top 2 airlines flying from Des Moines to Medford

Discover the top 2 airlines that operate flights from Des Moines to Medford. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$274Average$503FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$328Average$393FlexibilityNo cancel feeOn-time71%

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