$178+ Cheap flights from Des Moines to San Antonio (DSM - SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAT
Jun 12 — Jun 191
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to San Antonio
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Best
Last-minute
One-way
Cheapest flights from Des Moines to San AntonioExplore the most affordable flight options available from Des Moines to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 13, 2026.
Explore the most affordable flight options available from Des Moines to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 13, 2026.
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/172:45 pm
DSM
- SAT
1 stop6h 47m
Delta
Tue 6/236:05 am
SAT
- DSM
1 stop8h 00m
Delta
Deal found 5/11![Delta logo]()
$355
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:10 am
DSM
- SAT
2 stops6h 40m
Southwest
Wed 9/232:35 pm
SAT
- DSM
1 stop7h 20m
Southwest
Deal found 5/12![Southwest logo]()
$360
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/243:45 pm
DSM
- SAT
1 stop7h 55m
Southwest
Wed 7/15:45 am
SAT
- DSM
1 stop9h 20m
Southwest
Deal found 5/10![Southwest logo]()
$361
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:39 pm
DSM
- SAT
1 stop5h 54m
Delta
Sat 6/137:40 am
SAT
- DSM
1 stop8h 20m
Delta
Deal found 5/11![Delta logo]()
$374
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:35 am
DSM
- SAT
1 stop8h 00m
Delta
Tue 7/77:40 am
SAT
- DSM
1 stop5h 54m
Delta
Deal found 5/9![Delta logo]()
$381
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/277:02 pm
DSM
- SAT
1 stop4h 03m
American Airlines
Sat 7/48:00 am
SAT
- DSM
1 stop6h 17m
American Airlines
Deal found 5/12![American Airlines logo]()
$391
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/124:15 pm
DSM
- SAT
1 stop5h 13m
Delta
Sat 9/196:45 am
SAT
- DSM
1 stop6h 37m
Delta
Deal found 5/9![Delta logo]()
$393
Best flights from Des Moines to San AntonioDiscover carefully curated flight deals from Des Moines to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 13, 2026.
Discover carefully curated flight deals from Des Moines to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 13, 2026.
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:11 pm
DSM
- SAT
1 stop7h 48m
American Airlines
Tue 10/2712:39 pm
SAT
- DSM
1 stop6h 17m
American Airlines
Deal found 5/8![American Airlines logo]()
$355
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:50 am
DSM
- SAT
1 stop4h 59m
Delta
Tue 6/236:05 am
SAT
- DSM
1 stop8h 00m
Delta
Deal found 5/10![Delta logo]()
$355
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2911:34 am
DSM
- SAT
1 stop5h 21m
United Airlines
Tue 6/25:30 am
SAT
- DSM
1 stop5h 12m
United Airlines
Deal found 5/11![United Airlines logo]()
$381
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:25 pm
DSM
- SAT
1 stop4h 45m
Southwest
Sun 8/163:50 pm
SAT
- DSM
2 stops6h 45m
Southwest
Deal found 5/9![Southwest logo]()
$412
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/174:48 pm
DSM
- SAT
1 stop4h 18m
American Airlines
Tue 6/235:35 pm
SAT
- DSM
1 stop5h 17m
American Airlines
Deal found 5/12![American Airlines logo]()
$355
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/41:35 pm
DSM
- SAT
1 stop7h 19m
United Airlines
Sun 6/145:30 pm
SAT
- DSM
1 stop5h 21m
United Airlines
Deal found 5/9![United Airlines logo]()
$400
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:20 am
DSM
- SAT
2 stops9h 15m
Southwest
Sat 7/185:30 am
SAT
- DSM
2 stops9h 20m
Southwest
Deal found 5/8![Southwest logo]()
$417
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/21:41 pm
DSM
- SAT
1 stop6h 59m
American Airlines
Tue 7/79:31 am
SAT
- DSM
1 stop6h 29m
American Airlines
Deal found 5/8![American Airlines logo]()
$381
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:17 pm
DSM
- SAT
1 stop6h 38m
United Airlines
Wed 6/35:30 pm
SAT
- DSM
1 stop5h 21m
United Airlines
Deal found 5/8![United Airlines logo]()
$435
Last-minute flights from Des Moines to San AntonioDiscover last-minute flight deals from Des Moines to San Antonio. Data last updated May 13, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to San Antonio. Data last updated May 13, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2911:34 am
DSM
- SAT
1 stop5h 21m
United Airlines
Tue 6/25:30 am
SAT
- DSM
1 stop5h 12m
United Airlines
Deal found 5/11![United Airlines logo]()
$381
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/41:35 pm
DSM
- SAT
1 stop7h 19m
United Airlines
Sun 6/145:30 pm
SAT
- DSM
1 stop5h 21m
United Airlines
Deal found 5/9![United Airlines logo]()
$400
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:02 pm
DSM
- SAT
1 stop4h 03m
American Airlines
Mon 6/155:52 pm
SAT
- DSM
1 stop6h 20m
American Airlines
Deal found 5/11![American Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:40 pm
DSM
- SAT
1 stop7h 25m
Southwest
Mon 6/152:10 pm
SAT
- DSM
2 stops9h 20m
Southwest
Deal found 5/11![Southwest logo]()
$405
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:39 pm
DSM
- SAT
1 stop5h 54m
Delta
Sat 6/137:40 am
SAT
- DSM
1 stop8h 20m
Delta
Deal found 5/11![Delta logo]()
$374
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/172:45 pm
DSM
- SAT
1 stop6h 47m
Delta
Tue 6/236:05 am
SAT
- DSM
1 stop8h 00m
Delta
Deal found 5/11![Delta logo]()
$355
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/243:45 pm
DSM
- SAT
1 stop7h 55m
Southwest
Wed 7/15:45 am
SAT
- DSM
1 stop9h 20m
Southwest
Deal found 5/10![Southwest logo]()
$361
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/277:02 pm
DSM
- SAT
1 stop4h 03m
American Airlines
Sat 7/48:00 am
SAT
- DSM
1 stop6h 17m
American Airlines
Deal found 5/12![American Airlines logo]()
$391
One-way flights from Des Moines to San AntonioSearch for one-way flight options from Des Moines to San Antonio. Find affordable one-way fares based on user searches. Data last updated May 13, 2026.
Search for one-way flight options from Des Moines to San Antonio. Find affordable one-way fares based on user searches. Data last updated May 13, 2026.
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/161:37 pm
DSM
- SAT
1 stop6h 59m
American Airlines
Deal found 5/12![American Airlines logo]()
$178
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:23 am
DSM
- SAT
2 stops8h 30m
United Airlines
Deal found 5/10![United Airlines logo]()
$183
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:30 am
DSM
- SAT
1 stop4h 29m
American Airlines
Deal found 5/12![American Airlines logo]()
$197
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/114:40 pm
DSM
- SAT
2 stops8h 20m
Southwest
Deal found 5/12![Southwest logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/144:01 pm
DSM
- SAT
3 stops52h 10m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$220
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:30 am
DSM
- SAT
1 stop4h 29m
American Airlines
Deal found 5/11![American Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:02 pm
DSM
- SAT
3 stops49h 54m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$242
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:10 am
DSM
- SAT
2 stops9h 50m
Southwest
Deal found 5/13![Southwest logo]()
$270
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:10 am
DSM
- SAT
2 stops10h 30m
Southwest
Deal found 5/11![Southwest logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/274:22 pm
DSM
- SAT
3 stops42h 28m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/219:34 pm
DSM
- SAT
2 stops21h 25m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$331
Find flight deals from Des Moines to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $355 (American Airlines) |
One-way from | $178 (American Airlines) |
Popular in | March |
Cheapest in | August |
Average price | $386 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Des Moines to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Wed 10/21
12:11 pm-7:59 pm
1 stop7h 48m
San Antonio
Tue 10/27
12:39 pm-6:56 pm
1 stop6h 17m
$355
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Wed 6/17
6:50 am-11:49 am
1 stop4h 59m
San Antonio
Tue 6/23
6:05 am-2:05 pm
1 stop8h 00m
$355
Quickest round-trip
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Wed 6/17
4:48 pm-9:06 pm
1 stop4h 18m
San Antonio
Tue 6/23
5:35 pm-10:52 pm
1 stop5h 17m
$355
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Fri 5/29
11:34 am-4:55 pm
1 stop5h 21m
San Antonio
Tue 6/2
5:30 am-10:42 am
1 stop5h 12m
$381
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Thu 7/2
1:41 pm-8:40 pm
1 stop6h 59m
San Antonio
Tue 7/7
9:31 am-4:00 pm
1 stop6h 29m
$381
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Thu 6/4
1:35 pm-8:54 pm
1 stop7h 19m
San Antonio
Sun 6/14
5:30 pm-10:51 pm
1 stop5h 21m
$400
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Fri 8/14
2:25 pm-7:10 pm
1 stop4h 45m
San Antonio
Sun 8/16
3:50 pm-10:35 pm
2 stops6h 45m
$412
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Wed 7/15
5:20 am-2:35 pm
2 stops9h 15m
San Antonio
Sat 7/18
5:30 am-2:50 pm
2 stops9h 20m
$417
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Tue 6/2
5:17 pm-11:55 pm
1 stop6h 38m
San Antonio
Wed 6/3
5:30 pm-10:51 pm
1 stop5h 21m
$435
Cheapest one-way
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Wed 9/16
5:25 pm-11:12 pm
1 stop5h 47m
$178
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Des Moines to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to San Antonio in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Des Moines with our price prediction graph.
DSM-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to San Antonio
How far ahead should I book a flight from Des Moines to San Antonio?
The price you pay for your flight from Des Moines to San Antonio may vary depending on when you book. For the best chance of a lower fare, look to book 62 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to San Antonio?
Currently, August is the cheapest month in which you can book a flight from Des Moines to San Antonio (average of $321). Flying from Des Moines to San Antonio in March is currently the most expensive (average of $587). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to San Antonio?
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated May 13, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Des Moines to San Antonio. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Des Moines to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
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Des Moines and San Antonio flights
Browse other Des Moines and San Antonio flight options. Last updated on May 13, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on May 13, 2026.
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Other flights to San Antonio
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Top 4 airlines flying from Des Moines to San Antonio
Discover the top 4 airlines that operate flights from Des Moines to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$213 | Average$387 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$262 | Average$378 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$435 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$359 | Average$421 | FlexibilityNo cancel fee | On-time63% |