$144+ Cheap flights from Des Moines to San Antonio (DSM - SAT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAT
Nov 1 — Nov 81
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to San Antonio
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One-way
Cheapest flights from Des Moines to San AntonioExplore the most affordable flight options available from Des Moines to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2026.
Explore the most affordable flight options available from Des Moines to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:25 pm -
1 stop23h 00m
Tue 11/310:29 pm -
1 stop15h 26m
Deal found 10/1![Multiple Airlines logo]()
$264
This CheapOair deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:30 pm -
1 stop22h 55m
Sun 11/88:20 pm -
1 stop23h 15m
Deal found 9/28![Frontier logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:00 pm -
1 stop15h 52m
Wed 10/2810:29 pm -
1 stop24h 21m
Deal found 9/30![Multiple Airlines logo]()
$321
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:52 pm -
1 stop5h 41m
Wed 11/186:30 am -
1 stop7h 43m
Deal found 9/29![Delta logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:43 am -
2 stops27h 32m
Tue 10/2710:29 pm -
1 stop15h 23m
Deal found 9/30![Multiple Airlines logo]()
$326
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:00 am -
2 stops7h 38m
Mon 11/21:52 pm -
1 stop6h 44m
Deal found 9/28![United Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:29 am -
1 stop6h 27m
Thu 11/56:40 pm -
1 stop5h 46m
Deal found 9/29![American Airlines logo]()
$332
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:30 pm -
2 stops8h 15m
Tue 10/276:50 am -
2 stops7h 30m
Deal found 10/1![Southwest logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:11 pm -
1 stop24h 23m
Mon 11/210:29 pm -
2 stops40h 09m
Deal found 10/2![Multiple Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:11 pm -
1 stop24h 23m
Thu 10/299:25 am -
2 stops23h 00m
Deal found 10/2![Multiple Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:25 am -
2 stops7h 37m
Wed 11/185:00 am -
1 stop4h 07m
Deal found 9/28![American Airlines logo]()
$344
Best flights from Des Moines to San AntonioDiscover carefully curated flight deals from Des Moines to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 2, 2026.
Discover carefully curated flight deals from Des Moines to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 2, 2026.
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:59 pm -
1 stop7h 07m
Mon 11/164:32 pm -
1 stop6h 03m
Deal found 10/1![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/161:23 pm -
1 stop7h 11m
Mon 12/215:39 pm -
1 stop5h 38m
Deal found 9/30![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:00 am -
1 stop7h 05m
Fri 12/43:00 pm -
2 stops7h 00m
Deal found 9/30![Southwest logo]()
$422
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:35 am -
1 stop7h 00m
Mon 11/26:50 am -
1 stop8h 26m
Deal found 9/27![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:00 am -
1 stop7h 38m
Thu 11/121:52 pm -
1 stop6h 44m
Deal found 9/29![United Airlines logo]()
$325
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:57 am -
1 stop6h 37m
Tue 11/37:50 am -
1 stop7h 26m
Deal found 9/27![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:00 am -
2 stops7h 38m
Sat 11/145:30 am -
2 stops6h 50m
Deal found 10/1![United Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:54 pm -
1 stop5h 39m
Mon 11/27:50 am -
1 stop7h 26m
Deal found 9/27![Delta logo]()
$345
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/176:15 am -
1 stop5h 32m
Sun 3/215:20 am -
1 stop7h 14m
Deal found 9/28![United Airlines logo]()
$417
This Delta deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:01 pm -
1 stop5h 09m
Tue 10/2710:48 am -
1 stop7h 21m
Deal found 10/2![Delta logo]()
$391
This Delta deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:03 pm -
1 stop6h 45m
Sat 10/312:30 pm -
1 stop6h 30m
Deal found 10/2![Delta logo]()
$391
Last-minute flights from Des Moines to San AntonioDiscover last-minute flight deals from Des Moines to San Antonio. Data last updated October 2, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to San Antonio. Data last updated October 2, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:43 am -
2 stops27h 32m
Tue 10/2710:29 pm -
1 stop15h 23m
Deal found 9/30![Multiple Airlines logo]()
$326
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:00 pm -
1 stop15h 52m
Wed 10/2810:29 pm -
1 stop24h 21m
Deal found 9/30![Multiple Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:25 pm -
1 stop23h 00m
Tue 11/310:29 pm -
1 stop15h 26m
Deal found 10/1![Multiple Airlines logo]()
$264
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:30 pm -
2 stops8h 15m
Tue 11/31:00 pm -
2 stops7h 45m
Deal found 10/1![Southwest logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:11 pm -
1 stop24h 23m
Mon 11/210:29 pm -
2 stops40h 09m
Deal found 10/2![Multiple Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:11 pm -
1 stop24h 23m
Thu 10/299:25 am -
2 stops23h 00m
Deal found 10/2![Multiple Airlines logo]()
$341
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:00 am -
2 stops7h 38m
Mon 11/21:52 pm -
1 stop6h 44m
Deal found 9/28![United Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:29 am -
1 stop6h 27m
Thu 11/56:40 pm -
1 stop5h 46m
Deal found 9/29![American Airlines logo]()
$332
This CheapOair deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:30 pm -
1 stop22h 55m
Sun 11/88:20 pm -
1 stop23h 15m
Deal found 9/28![Frontier logo]()
$292
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:59 pm -
1 stop7h 07m
Mon 11/164:32 pm -
1 stop6h 03m
Deal found 9/30![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:25 am -
2 stops7h 37m
Wed 11/185:00 am -
1 stop4h 07m
Deal found 9/28![American Airlines logo]()
$344
One-way flights from Des Moines to San AntonioSearch for one-way flight options from Des Moines to San Antonio. Find affordable one-way fares based on user searches. Data last updated October 2, 2026.
Search for one-way flight options from Des Moines to San Antonio. Find affordable one-way fares based on user searches. Data last updated October 2, 2026.
This CheapOair deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:25 pm -
1 stop23h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Frontier logo]()
$144
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:22 pm -
1 stop6h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![United Airlines logo]()
$163
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/53:26 pm -
2 stops8h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![American Airlines logo]()
$182
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:32 pm -
1 stop4h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![American Airlines logo]()
$183
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/81:45 pm -
2 stops9h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![United Airlines logo]()
$188
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:01 pm -
1 stop5h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Delta logo]()
$210
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/211:27 pm -
2 stops9h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![United Airlines logo]()
$218
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:54 pm -
1 stop5h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Delta logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:00 pm -
2 stops21h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$220
Find flight deals from Des Moines to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $264 (Kiwi.com) |
One-way from | $144 (CheapOair) |
Popular in | June |
Cheapest in | November |
Average price | $416 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 2, 2026.
Use the filters below to find and compare flights from Des Moines to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSan Antonio
DSM Des Moines - SAT San Antonio
DSMSAT
Des Moines
Tue 1/5
5:15 pm-12:28 am
1 stop7h 13m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
Des MoinesSan Antonio
DSM Des Moines - SAT San Antonio
DSMSAT
Des Moines
Sat 10/24
5:22 pm-11:58 pm
1 stop6h 36m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
Quickest round-trip
Des MoinesSan Antonio
DSM Des Moines - SAT San Antonio
DSMSAT
Des Moines
Fri 12/11
7:32 pm-12:07 am
1 stop4h 35m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$183
Des MoinesSan Antonio
DSM Des Moines - SAT San Antonio
DSMSAT
Des Moines
Wed 10/21
1:27 pm-10:51 pm
2 stops9h 24m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$218
Des MoinesSan Antonio
DSM Des Moines - SAT San Antonio
DSMSAT
Des Moines
Tue 10/27
11:22 am-9:26 pm
2 stops10h 04m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$218
Des MoinesSan Antonio
DSM Des Moines - SAT San Antonio
DSMSAT
Des Moines
Fri 12/11
1:23 pm-10:59 pm
2 stops9h 36m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$238
Des MoinesSan Antonio
DSM Des Moines - SAT San Antonio
DSMSAT
Des Moines
Tue 11/10
2:59 pm-10:06 pm
1 stop7h 07m
San Antonio
Mon 11/16
4:32 pm-10:35 pm
1 stop6h 03m
$325
Des MoinesSan Antonio
DSM Des Moines - SAT San Antonio
DSMSAT
Des Moines
Wed 12/16
1:23 pm-8:34 pm
1 stop7h 11m
San Antonio
Mon 12/21
5:39 pm-11:17 pm
1 stop5h 38m
$325
Des MoinesSan Antonio
DSM Des Moines - SAT San Antonio
DSMSAT
Des Moines
Thu 10/29
5:35 am-12:35 pm
1 stop7h 00m
San Antonio
Mon 11/2
6:50 am-3:16 pm
1 stop8h 26m
$325
Des MoinesSan Antonio
DSM Des Moines - SAT San Antonio
DSMSAT
Des Moines
Wed 11/4
8:00 am-3:38 pm
1 stop7h 38m
San Antonio
Thu 11/12
1:52 pm-8:36 pm
1 stop6h 44m
$325
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Des Moines to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to San Antonio in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Des Moines with our price prediction graph.
DSM-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to San Antonio
How far ahead should I book a flight from Des Moines to San Antonio?
The price you pay for your flight from Des Moines to San Antonio may vary depending on when you book. For the best chance of a lower fare, look to book 18 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to San Antonio?
Currently, November is the cheapest month in which you can book a flight from Des Moines to San Antonio (average of $370). Flying from Des Moines to San Antonio in June is currently the most expensive (average of $760). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to San Antonio?
Airfare is below average for this route at the moment.
Des Moines to San Antonio flights typically cost between $367 and $543 in October.The cheapest round-trip price found within the last 5 days was $264 on Multiple Airlines (Oct 26-Nov 3).
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated October 2, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Des Moines to San Antonio. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Related info for your journey
Find useful and relevant information for your journey from Des Moines to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
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Top 4 airlines flying from Des Moines to San Antonio
Discover the top 4 airlines that operate flights from Des Moines to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$289 | Average$370 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$316 | Average$407 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$316 | Average$416 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$324 | Average$403 | FlexibilityNo cancel fee | On-time63% |