$120+ Cheap flights from San Antonio to Des Moines (SAT - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/19. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — DSM
Oct 4 — Oct 111
Round-trip
1 adult, Economy
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Find cheap flights from San Antonio to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Antonio to Des Moines
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Cheapest flights from San Antonio to Des MoinesExplore the most affordable flight options available from San Antonio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 4, 2026.
Explore the most affordable flight options available from San Antonio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 4, 2026.
This Frontier deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:20 pm -
1 stop23h 13m
Mon 9/218:30 pm -
1 stop22h 55m
Deal found 8/31![Frontier logo]()
$301
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:48 pm -
1 stop5h 16m
Tue 10/64:12 pm -
1 stop5h 48m
Deal found 9/3![American Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:30 pm -
1 stop6h 05m
Sat 10/35:45 am -
1 stop7h 13m
Deal found 9/3![United Airlines logo]()
$333
This CheapOair deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:20 pm -
1 stop14h 24m
Sun 9/2011:29 am -
1 stop7h 56m
Deal found 9/1![Frontier logo]()
$346
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:48 pm -
1 stop5h 16m
Fri 10/97:42 pm -
1 stop4h 17m
Deal found 9/3![American Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:40 am -
1 stop7h 28m
Sun 11/1511:36 am -
1 stop8h 12m
Deal found 9/2![Delta logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:20 pm -
2 stops23h 28m
Mon 9/218:30 pm -
1 stop22h 55m
Deal found 8/31![Multiple Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:35 am -
1 stop4h 45m
Thu 10/298:00 am -
1 stop5h 16m
Deal found 9/3![United Airlines logo]()
$405
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:30 am -
2 stops7h 02m
Fri 10/96:00 am -
1 stop4h 43m
Deal found 8/30![United Airlines logo]()
$406
Best flights from San Antonio to Des MoinesDiscover carefully curated flight deals from San Antonio to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 4, 2026.
Discover carefully curated flight deals from San Antonio to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 4, 2026.
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:40 am -
1 stop7h 28m
Sun 11/1511:36 am -
1 stop8h 12m
Deal found 9/2![Delta logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:20 pm -
2 stops23h 28m
Mon 9/218:30 pm -
1 stop22h 55m
Deal found 8/31![Multiple Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:52 pm -
1 stop6h 44m
Thu 10/299:00 am -
1 stop7h 55m
Deal found 8/31![United Airlines logo]()
$405
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:30 am -
2 stops7h 02m
Fri 10/96:00 am -
1 stop4h 43m
Deal found 8/30![United Airlines logo]()
$406
Last-minute flights from San Antonio to Des MoinesDiscover last-minute flight deals from San Antonio to Des Moines. Data last updated September 4, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Des Moines. Data last updated September 4, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:20 pm -
1 stop14h 24m
Sun 9/2011:29 am -
1 stop7h 56m
Deal found 9/1![Frontier logo]()
$346
This Frontier deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:20 pm -
1 stop23h 13m
Mon 9/218:30 pm -
1 stop22h 55m
Deal found 8/31![Frontier logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:20 pm -
2 stops23h 28m
Mon 9/218:30 pm -
1 stop22h 55m
Deal found 8/31![Multiple Airlines logo]()
$393
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:48 pm -
1 stop5h 16m
Tue 10/64:12 pm -
1 stop5h 48m
Deal found 9/3![American Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:30 pm -
1 stop6h 05m
Sat 10/35:45 am -
1 stop7h 13m
Deal found 9/3![United Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:48 pm -
1 stop5h 16m
Fri 10/97:42 pm -
1 stop4h 17m
Deal found 9/3![American Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:30 pm -
1 stop6h 05m
Fri 10/96:00 am -
1 stop4h 43m
Deal found 8/30![United Airlines logo]()
$401
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:35 am -
1 stop4h 45m
Thu 10/298:00 am -
1 stop5h 16m
Deal found 9/3![United Airlines logo]()
$405
One-way flights from San Antonio to Des MoinesSearch for one-way flight options from San Antonio to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 4, 2026.
Search for one-way flight options from San Antonio to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 4, 2026.
This Trip.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:20 pm -
1 stop14h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Frontier logo]()
$120
This CheapOair deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:20 pm -
1 stop14h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Frontier logo]()
$142
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:00 am -
1 stop4h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![American Airlines logo]()
$163
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:35 am -
2 stops8h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![United Airlines logo]()
$168
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:30 pm -
1 stop6h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![United Airlines logo]()
$176
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/236:45 am -
1 stop5h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Delta logo]()
$193
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/236:00 am -
2 stops7h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![American Airlines logo]()
$198
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/2312:24 pm -
2 stops9h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![United Airlines logo]()
$208
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/286:00 am -
1 stop5h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Delta logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2712:39 pm -
2 stops30h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Frontier logo]()
$213
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:10 pm -
2 stops9h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Southwest logo]()
$240
Find flight deals from San Antonio to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $301 (Frontier) |
One-way from | $120 (Jetabroad) |
Popular in | January |
Cheapest in | April |
Average price | $448 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 4, 2026.
Use the filters below to find and compare flights from San Antonio to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San AntonioDes Moines
SAT San Antonio - DSM Des Moines
SATDSM
San Antonio
Sat 9/19
8:20 pm-10:44 am
1 stop14h 24m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$120
San AntonioDes Moines
SAT San Antonio - DSM Des Moines
SATDSM
San Antonio
Sun 9/27
8:20 pm-7:33 pm
1 stop23h 13m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$120
Quickest round-trip
San AntonioDes Moines
SAT San Antonio - DSM Des Moines
SATDSM
San Antonio
Wed 11/18
5:00 am-9:15 am
1 stop4h 15m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
San AntonioDes Moines
SAT San Antonio - DSM Des Moines
SATDSM
San Antonio
Wed 11/18
7:35 am-4:07 pm
2 stops8h 32m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$168
San AntonioDes Moines
SAT San Antonio - DSM Des Moines
SATDSM
San Antonio
Fri 10/2
5:30 pm-11:35 pm
1 stop6h 05m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$176
San AntonioDes Moines
SAT San Antonio - DSM Des Moines
SATDSM
San Antonio
Sat 1/23
6:45 am-12:13 pm
1 stop5h 28m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$193
San AntonioDes Moines
SAT San Antonio - DSM Des Moines
SATDSM
San Antonio
Sat 1/23
12:24 pm-9:41 pm
2 stops9h 17m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$208
San AntonioDes Moines
SAT San Antonio - DSM Des Moines
SATDSM
San Antonio
Mon 12/28
6:00 am-11:51 am
1 stop5h 51m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$209
San AntonioDes Moines
SAT San Antonio - DSM Des Moines
SATDSM
San Antonio
Fri 12/18
6:25 am-11:15 am
1 stop4h 50m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$239
San AntonioDes Moines
SAT San Antonio - DSM Des Moines
SATDSM
San Antonio
Fri 11/13
6:40 am-2:08 pm
1 stop7h 28m
Des Moines
Sun 11/15
11:36 am-7:48 pm
1 stop8h 12m
$384
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from San Antonio to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Des Moines in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Antonio-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Antonio with our price prediction graph.
SAT-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Des Moines
What is the cheapest month to book a flight from San Antonio to Des Moines?
Currently, April is the cheapest month in which you can book a flight from San Antonio to Des Moines (average of $351). Flying from San Antonio to Des Moines in January is currently the most expensive (average of $830). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Antonio to Des Moines?
Airfare is below average for this route at the moment.
San Antonio to Des Moines flights typically cost between $426 and $557 in September.The cheapest round-trip price found within the last 5 days was $301 on Frontier (Sep 17-Sep 21).
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 4, 2026.
See what other customers who have flown with United Airlines and American Airlines from San Antonio to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Comfort
7.3
Overall
7.4
Boarding
7.7
Food
6.7
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Crew
8.1
Comfort
7.3
Overall
7.4
Boarding
7.7
Food
6.7
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Crew
8.1
Comfort
7.3
Overall
7.4
Boarding
7.7
Food
6.7
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Other flights to Des Moines
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San Antonio and Des Moines flights
Browse other San Antonio and Des Moines flight options. Last updated on September 4, 2026.
Other flights from San Antonio
Browse through other flights departing from San Antonio. Flights are based on user searches made on Cheapflights and were last updated on September 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from San Antonio to Des Moines
Discover the top 2 airlines that operate flights from San Antonio to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$283 | Average$466 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$386 | Average$464 | FlexibilityNo cancel fee | On-time69% |