$159+ Cheap flights from San Antonio to Des Moines (SAT - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — DSM
Jul 16 — Jul 231
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Antonio to Des MoinesExplore the most affordable flight options available from San Antonio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2026.
Explore the most affordable flight options available from San Antonio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2026.
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:20 am
SAT
- DSM
1 stop5h 23m
Delta
Tue 8/116:55 am
DSM
- SAT
1 stop4h 54m
Delta
Deal found 6/12![Delta logo]()
$263
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:30 am
SAT
- DSM
2 stops7h 02m
United Airlines
Wed 9/1611:33 am
DSM
- SAT
1 stop5h 22m
United Airlines
Deal found 6/14![United Airlines logo]()
$322
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:20 am
SAT
- DSM
1 stop5h 23m
Delta
Thu 8/135:40 am
DSM
- SAT
1 stop5h 30m
Delta
Deal found 6/15![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:30 am
SAT
- DSM
1 stop7h 34m
Delta
Thu 8/136:35 pm
DSM
- SAT
1 stop5h 53m
Delta
Deal found 6/15![Delta logo]()
$341
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:35 am
SAT
- DSM
1 stop7h 40m
United Airlines
Wed 10/76:00 am
DSM
- SAT
1 stop6h 11m
United Airlines
Deal found 6/11![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:55 pm
SAT
- DSM
2 stops8h 05m
Southwest
Wed 9/166:10 am
DSM
- SAT
2 stops11h 45m
Southwest
Deal found 6/14![Southwest logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:39 pm
SAT
- DSM
1 stop17h 55m
Multiple Airlines
Mon 8/1010:06 pm
DSM
- SAT
2 stops20h 48m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:20 am
SAT
- DSM
1 stop5h 23m
Delta
Wed 8/1210:59 am
DSM
- SAT
1 stop6h 12m
Delta
Deal found 6/15![Delta logo]()
$362
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:00 am
SAT
- DSM
1 stop4h 01m
American Airlines
Mon 8/104:13 pm
DSM
- SAT
1 stop6h 37m
American Airlines
Deal found 6/14![American Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:57 pm
SAT
- DSM
1 stop4h 38m
United Airlines
Tue 7/78:00 am
DSM
- SAT
1 stop8h 29m
United Airlines
Deal found 6/12![United Airlines logo]()
$367
Best flights from San Antonio to Des MoinesDiscover carefully curated flight deals from San Antonio to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 16, 2026.
Discover carefully curated flight deals from San Antonio to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 16, 2026.
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:30 am
SAT
- DSM
2 stops7h 02m
United Airlines
Wed 9/1611:33 am
DSM
- SAT
1 stop5h 22m
United Airlines
Deal found 6/14![United Airlines logo]()
$322
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/112:40 pm
SAT
- DSM
2 stops9h 20m
Southwest
Wed 8/56:10 am
DSM
- SAT
1 stop6h 40m
Southwest
Deal found 6/14![Southwest logo]()
$367
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:35 pm
SAT
- DSM
1 stop6h 24m
American Airlines
Mon 8/36:33 pm
DSM
- SAT
1 stop5h 37m
American Airlines
Deal found 6/12![American Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:35 am
SAT
- DSM
1 stop7h 40m
United Airlines
Wed 10/76:00 am
DSM
- SAT
1 stop6h 11m
United Airlines
Deal found 6/11![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/712:40 pm
SAT
- DSM
2 stops8h 35m
Southwest
Mon 8/103:50 pm
DSM
- SAT
1 stop7h 25m
Southwest
Deal found 6/15![Southwest logo]()
$379
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:30 am
SAT
- DSM
1 stop5h 22m
United Airlines
Wed 8/125:21 pm
DSM
- SAT
1 stop6h 36m
United Airlines
Deal found 6/15![United Airlines logo]()
$397
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:40 am
SAT
- DSM
1 stop5h 02m
United Airlines
Tue 8/116:00 am
DSM
- SAT
2 stops9h 43m
United Airlines
Deal found 6/16![United Airlines logo]()
$402
Last-minute flights from San Antonio to Des MoinesDiscover last-minute flight deals from San Antonio to Des Moines. Data last updated June 16, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Des Moines. Data last updated June 16, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:52 pm
SAT
- DSM
1 stop6h 20m
American Airlines
Wed 7/15:00 am
DSM
- SAT
1 stop8h 30m
American Airlines
Deal found 6/12![American Airlines logo]()
$421
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2712:40 pm
SAT
- DSM
2 stops9h 15m
Southwest
Wed 7/13:45 pm
DSM
- SAT
1 stop7h 55m
Southwest
Deal found 6/12![Southwest logo]()
$479
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:57 pm
SAT
- DSM
1 stop4h 38m
United Airlines
Tue 7/78:00 am
DSM
- SAT
1 stop8h 29m
United Airlines
Deal found 6/12![United Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:01 am
SAT
- DSM
1 stop4h 10m
American Airlines
Tue 7/74:48 pm
DSM
- SAT
1 stop6h 10m
American Airlines
Deal found 6/12![American Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:47 pm
SAT
- DSM
1 stop6h 22m
American Airlines
Wed 7/84:48 pm
DSM
- SAT
1 stop4h 15m
American Airlines
Deal found 6/12![American Airlines logo]()
$427
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:30 am
SAT
- DSM
1 stop7h 20m
Southwest
Wed 7/83:45 pm
DSM
- SAT
2 stops7h 15m
Southwest
Deal found 6/12![Southwest logo]()
$432
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:08 pm
SAT
- DSM
1 stop4h 50m
American Airlines
Thu 7/167:13 pm
DSM
- SAT
1 stop4h 45m
American Airlines
Deal found 6/11![American Airlines logo]()
$407
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:08 pm
SAT
- DSM
1 stop4h 50m
American Airlines
Sun 7/195:12 am
DSM
- SAT
1 stop4h 56m
American Airlines
Deal found 6/16![American Airlines logo]()
$417
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1312:50 pm
SAT
- DSM
2 stops9h 35m
Southwest
Mon 7/204:40 pm
DSM
- SAT
1 stop7h 30m
Southwest
Deal found 6/13![Southwest logo]()
$452
One-way flights from San Antonio to Des MoinesSearch for one-way flight options from San Antonio to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 16, 2026.
Search for one-way flight options from San Antonio to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 16, 2026.
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:20 am
SAT
- DSM
1 stop5h 23m
Delta
Deal found 6/15![Delta logo]()
$159
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:30 am
SAT
- DSM
2 stops8h 50m
United Airlines
Deal found 6/14![United Airlines logo]()
$164
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:25 am
SAT
- DSM
1 stop7h 40m
Delta
Deal found 6/15![Delta logo]()
$171
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:35 am
SAT
- DSM
2 stops8h 44m
United Airlines
Deal found 6/15![United Airlines logo]()
$176
This Booking.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/257:51 pm
SAT
- DSM
1 stop17h 40m
Frontier
Deal found 6/12![Frontier logo]()
$197
This Trip.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/287:51 pm
SAT
- DSM
1 stop17h 40m
Frontier
Deal found 6/15![Frontier logo]()
$199
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:24 am
SAT
- DSM
1 stop6h 40m
American Airlines
Deal found 6/15![American Airlines logo]()
$204
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:25 pm
SAT
- DSM
2 stops6h 45m
Southwest
Deal found 6/13![Southwest logo]()
$209
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:01 am
SAT
- DSM
1 stop4h 10m
American Airlines
Deal found 6/13![American Airlines logo]()
$214
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:30 am
SAT
- DSM
2 stops8h 46m
United Airlines
Deal found 6/15![United Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/99:55 am
SAT
- DSM
2 stops36h 20m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$236
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:24 pm
SAT
- DSM
1 stop6h 11m
American Airlines
Deal found 6/12![American Airlines logo]()
$244
Find flight deals from San Antonio to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $263 (Delta) |
One-way from | $159 (Delta) |
Popular in | May |
Cheapest in | September |
Average price | $555 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
Use the filters below to find and compare flights from San Antonio to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Wed 9/9
5:30 am-12:32 pm
2 stops7h 02m
Des Moines
Wed 9/16
11:33 am-4:55 pm
1 stop5h 22m
$322
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Tue 10/6
6:35 am-2:15 pm
1 stop7h 40m
Des Moines
Wed 10/7
6:00 am-12:11 pm
1 stop6h 11m
$343
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Sat 8/1
12:40 pm-10:00 pm
2 stops9h 20m
Des Moines
Wed 8/5
6:10 am-12:50 pm
1 stop6h 40m
$367
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Fri 8/7
12:40 pm-9:15 pm
2 stops8h 35m
Des Moines
Mon 8/10
3:50 pm-11:15 pm
1 stop7h 25m
$379
Quickest round-trip
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Tue 8/11
5:30 am-10:52 am
1 stop5h 22m
Des Moines
Wed 8/12
5:21 pm-11:57 pm
1 stop6h 36m
$397
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Wed 8/5
5:40 am-10:42 am
1 stop5h 02m
Des Moines
Tue 8/11
6:00 am-3:43 pm
2 stops9h 43m
$402
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Fri 7/31
5:35 pm-11:59 pm
1 stop6h 24m
Des Moines
Mon 8/3
6:33 pm-12:10 am
1 stop5h 37m
$407
Cheapest one-way
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Tue 8/25
6:30 am-2:04 pm
1 stop7h 34m
$159
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Wed 9/9
6:48 pm-12:04 am
1 stop5h 16m
$159
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Wed 9/9
5:30 am-2:20 pm
2 stops8h 50m
$164
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from San Antonio to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Des Moines in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Antonio-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Antonio with our price prediction graph.
SAT-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Des Moines
What is the cheapest month to book a flight from San Antonio to Des Moines?
Currently, September is the cheapest month in which you can book a flight from San Antonio to Des Moines (average of $297). Flying from San Antonio to Des Moines in May is currently the most expensive (average of $667). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Antonio to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated June 16, 2026.
See what other customers who have flown with United Airlines and American Airlines from San Antonio to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Food
6.6
Overall
7.4
Boarding
7.7
Comfort
7.3
Entertainment
7.1
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Crew
8.1
Food
6.6
Overall
7.4
Boarding
7.7
Comfort
7.3
Entertainment
7.1
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Crew
8.1
Food
6.6
Overall
7.4
Boarding
7.7
Comfort
7.3
Entertainment
7.1
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 16, 2026.
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Top 2 airlines flying from San Antonio to Des Moines
Discover the top 2 airlines that operate flights from San Antonio to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$263 | Average$436 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$276 | Average$426 | FlexibilityNo cancel fee | On-time71% |