$263+ Cheap flights from Charleston, WV to Des Moines (CRW - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/22. Fares are subject to change and may not be available on all flights or dates of travel.
CRW — DSM
Jun 6 — Jun 131
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Des Moines
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Best
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Cheapest flights from Charleston to Des MoinesExplore the most affordable flight options available from Charleston to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 7, 2026.
Explore the most affordable flight options available from Charleston to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 7, 2026.
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:55 pm
CRW
- DSM
1 stop4h 36m
Delta
Wed 7/111:42 am
DSM
- CRW
1 stop5h 33m
Delta
Deal found 5/3![Delta logo]()
$298
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:00 am
CRW
- DSM
1 stop5h 43m
Delta
Mon 6/295:35 am
DSM
- CRW
1 stop7h 27m
Delta
Deal found 5/3![Delta logo]()
$328
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/258:05 pm
CRW
- DSM
1 stop5h 07m
American Airlines
Mon 6/291:37 pm
DSM
- CRW
1 stop4h 58m
American Airlines
Deal found 5/3![American Airlines logo]()
$373
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:57 pm
CRW
- DSM
1 stop5h 54m
United Airlines
Wed 7/13:24 pm
DSM
- CRW
1 stop4h 23m
United Airlines
Deal found 5/3![United Airlines logo]()
$378
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:55 pm
CRW
- DSM
1 stop4h 36m
Delta
Mon 6/295:00 pm
DSM
- CRW
1 stop5h 31m
Delta
Deal found 5/3![Delta logo]()
$408
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:00 am
CRW
- DSM
1 stop4h 27m
United Airlines
Mon 5/2511:23 am
DSM
- CRW
1 stop4h 59m
United Airlines
Deal found 5/6![United Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:42 am
CRW
- DSM
1 stop7h 10m
American Airlines
Wed 7/11:37 pm
DSM
- CRW
1 stop4h 58m
American Airlines
Deal found 5/3![American Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/138:06 pm
CRW
- DSM
1 stop5h 03m
American Airlines
Fri 7/178:50 pm
DSM
- CRW
2 stops12h 40m
American Airlines
Deal found 5/6![American Airlines logo]()
$448
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2610:06 am
CRW
- DSM
1 stop28h 24m
Multiple Airlines
Wed 7/110:59 am
DSM
- CRW
2 stops21h 17m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$477
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:50 pm
CRW
- DSM
1 stop6h 34m
United Airlines
Sun 5/241:18 pm
DSM
- CRW
1 stop6h 29m
United Airlines
Deal found 5/4![United Airlines logo]()
$479
Best flights from Charleston to Des MoinesDiscover carefully curated flight deals from Charleston to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 7, 2026.
Discover carefully curated flight deals from Charleston to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 7, 2026.
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:55 pm
CRW
- DSM
1 stop4h 36m
Delta
Tue 6/3011:42 am
DSM
- CRW
1 stop5h 33m
Delta
Deal found 5/3![Delta logo]()
$298
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:15 am
CRW
- DSM
1 stop6h 37m
American Airlines
Sat 5/233:24 pm
DSM
- CRW
1 stop5h 42m
American Airlines
Deal found 5/4![American Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:00 am
CRW
- DSM
1 stop4h 27m
United Airlines
Mon 5/2511:23 am
DSM
- CRW
1 stop4h 59m
United Airlines
Deal found 5/6![United Airlines logo]()
$423
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:55 pm
CRW
- DSM
1 stop4h 36m
Delta
Wed 7/111:42 am
DSM
- CRW
1 stop5h 33m
Delta
Deal found 5/3![Delta logo]()
$298
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:00 am
CRW
- DSM
1 stop5h 43m
Delta
Mon 6/295:35 am
DSM
- CRW
1 stop7h 27m
Delta
Deal found 5/3![Delta logo]()
$328
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/138:06 pm
CRW
- DSM
1 stop5h 03m
American Airlines
Fri 7/178:50 pm
DSM
- CRW
2 stops12h 40m
American Airlines
Deal found 5/6![American Airlines logo]()
$448
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:50 pm
CRW
- DSM
1 stop6h 34m
United Airlines
Sun 5/241:18 pm
DSM
- CRW
1 stop6h 29m
United Airlines
Deal found 5/4![United Airlines logo]()
$479
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:55 pm
CRW
- DSM
1 stop4h 36m
Delta
Wed 7/16:50 am
DSM
- CRW
2 stops15h 41m
Delta
Deal found 5/3![Delta logo]()
$483
Last-minute flights from Charleston to Des MoinesDiscover last-minute flight deals from Charleston to Des Moines. Data last updated May 7, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Des Moines. Data last updated May 7, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:50 pm
CRW
- DSM
1 stop6h 34m
United Airlines
Sun 5/241:18 pm
DSM
- CRW
1 stop6h 29m
United Airlines
Deal found 5/4![United Airlines logo]()
$479
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:00 am
CRW
- DSM
1 stop4h 27m
United Airlines
Mon 5/2511:23 am
DSM
- CRW
1 stop4h 59m
United Airlines
Deal found 5/6![United Airlines logo]()
$423
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:57 pm
CRW
- DSM
1 stop5h 54m
United Airlines
Wed 7/13:24 pm
DSM
- CRW
1 stop4h 23m
United Airlines
Deal found 5/3![United Airlines logo]()
$378
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:55 pm
CRW
- DSM
1 stop4h 36m
Delta
Mon 6/295:00 pm
DSM
- CRW
1 stop5h 31m
Delta
Deal found 5/3![Delta logo]()
$408
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:55 pm
CRW
- DSM
1 stop4h 36m
Delta
Wed 7/111:42 am
DSM
- CRW
1 stop5h 33m
Delta
Deal found 5/3![Delta logo]()
$298
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/258:05 pm
CRW
- DSM
1 stop5h 07m
American Airlines
Mon 6/291:37 pm
DSM
- CRW
1 stop4h 58m
American Airlines
Deal found 5/3![American Airlines logo]()
$373
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:00 am
CRW
- DSM
1 stop5h 43m
Delta
Mon 6/295:35 am
DSM
- CRW
1 stop7h 27m
Delta
Deal found 5/3![Delta logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2610:06 am
CRW
- DSM
1 stop28h 24m
Multiple Airlines
Wed 7/110:59 am
DSM
- CRW
2 stops21h 17m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$477
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:42 am
CRW
- DSM
1 stop7h 10m
American Airlines
Wed 7/11:37 pm
DSM
- CRW
1 stop4h 58m
American Airlines
Deal found 5/3![American Airlines logo]()
$439
One-way flights from Charleston to Des MoinesSearch for one-way flight options from Charleston to Des Moines. Find affordable one-way fares based on user searches. Data last updated May 7, 2026.
Search for one-way flight options from Charleston to Des Moines. Find affordable one-way fares based on user searches. Data last updated May 7, 2026.
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:05 pm
CRW
- DSM
1 stop5h 07m
American Airlines
Deal found 5/7![American Airlines logo]()
$263
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/225:57 pm
CRW
- DSM
3 stops19h 39m
United Airlines
Deal found 5/7![United Airlines logo]()
$1,394
Find flight deals from Charleston to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CRW) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $298 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 7, 2026.
Use the filters below to find and compare flights from Charleston to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonDes Moines
CRW - DSM
CRWDSM
Charleston Yeager
Wed 6/24
6:55 pm-10:31 pm
1 stop4h 36m
Des Moines
Tue 6/30
11:42 am-6:15 pm
1 stop5h 33m
$298
CharlestonDes Moines
CRW - DSM
CRWDSM
Charleston Yeager
Wed 6/24
6:55 pm-10:31 pm
1 stop4h 36m
Des Moines
Wed 7/1
11:42 am-6:15 pm
1 stop5h 33m
$298
CharlestonDes Moines
CRW - DSM
CRWDSM
Charleston Yeager
Tue 5/19
7:15 am-12:52 pm
1 stop6h 37m
Des Moines
Sat 5/23
3:24 pm-10:06 pm
1 stop5h 42m
$328
CharlestonDes Moines
CRW - DSM
CRWDSM
Charleston Yeager
Fri 6/26
6:00 am-10:43 am
1 stop5h 43m
Des Moines
Mon 6/29
5:35 am-2:02 pm
1 stop7h 27m
$328
Quickest round-trip
CharlestonDes Moines
CRW - DSM
CRWDSM
Charleston Yeager
Thu 5/21
7:00 am-10:27 am
1 stop4h 27m
Des Moines
Mon 5/25
11:23 am-5:22 pm
1 stop4h 59m
$423
CharlestonDes Moines
CRW - DSM
CRWDSM
Charleston Yeager
Mon 7/13
8:06 pm-12:09 am
1 stop5h 03m
Des Moines
Fri 7/17
8:50 pm-10:30 am
2 stops12h 40m
$448
CharlestonDes Moines
CRW - DSM
CRWDSM
Charleston Yeager
Wed 5/20
5:50 pm-11:24 pm
1 stop6h 34m
Des Moines
Sun 5/24
1:18 pm-8:47 pm
1 stop6h 29m
$479
CharlestonDes Moines
CRW - DSM
CRWDSM
Charleston Yeager
Thu 6/25
6:55 pm-10:31 pm
1 stop4h 36m
Des Moines
Wed 7/1
6:50 am-11:31 pm
2 stops15h 41m
$483
Cheapest one-way
Quickest one-way
CharlestonDes Moines
CRW - DSM
CRWDSM
Charleston Yeager
Mon 6/22
5:57 pm-12:36 pm
3 stops19h 39m
$1,394
Sorted by cheapest first
Compare providers for flights from Charleston to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Des Moines in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston, West Virginia-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston, West Virginia-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston, West Virginia-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston, West Virginia-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston, West Virginia-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Charleston with our price prediction graph.
CRW-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated May 7, 2026.
Read reviews from past customers who have flown United Airlines from Charleston to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Crew
8.1
Food
6.6
Overall
7.4
Boarding
7.7
Comfort
7.3
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Entertainment
7.1
Crew
8.1
Food
6.6
Overall
7.4
Boarding
7.7
Comfort
7.3
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Related info for your journey
Find useful and relevant information for your journey from Charleston to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny
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Charleston and Des Moines flights
Browse other Charleston and Des Moines flight options. Last updated on May 7, 2026.
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Top airline flying from Charleston to Des Moines
Discover the top airline that operate flights from Charleston to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$308 | Average$455 | FlexibilityNo cancel fee | On-time69% |