$155+ Cheap flights from Pittsburgh to Des Moines (PIT - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — DSM
Aug 26 — Sep 21
Round-trip
1 adult, Economy
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Find cheap flights from Pittsburgh to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Pittsburgh to Des Moines
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Cheapest flights from Pittsburgh to Des MoinesExplore the most affordable flight options available from Pittsburgh to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Juli 27, 2026.
Explore the most affordable flight options available from Pittsburgh to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Juli 27, 2026.
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 8/177:30 pm
PIT
- DSM
1 stop3h 40m
Southwest
Do 8/205:40 am
DSM
- PIT
1 stop4h 05m
Southwest
Deal found 7/22![Southwest logo]()
$303
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 10/17:00 am
PIT
- DSM
1 stop4h 31m
United Airlines
Mo 10/51:24 pm
DSM
- PIT
1 stop6h 12m
United Airlines
Deal found 7/27![United Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 9/105:35 am
PIT
- DSM
2 stops9h 10m
Southwest
Mo 9/145:40 am
DSM
- PIT
2 stops6h 30m
Southwest
Deal found 7/23![Southwest logo]()
$313
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 10/17:45 pm
PIT
- DSM
1 stop4h 10m
Southwest
Mo 10/55:10 am
DSM
- PIT
2 stops6h 45m
Southwest
Deal found 7/27![Southwest logo]()
$314
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 10/312:20 pm
PIT
- DSM
2 stops9h 25m
Southwest
Mi 10/75:35 am
DSM
- PIT
2 stops6h 20m
Southwest
Deal found 7/25![Southwest logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 9/251:25 pm
PIT
- DSM
1 stop9h 43m
Multiple Airlines
So 9/279:29 am
DSM
- PIT
1 stop12h 24m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$337
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 9/184:06 pm
PIT
- DSM
1 stop4h 15m
American Airlines
Mo 9/211:09 pm
DSM
- PIT
1 stop6h 51m
American Airlines
Deal found 7/26![American Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 9/410:45 am
PIT
- DSM
1 stop4h 31m
United Airlines
So 9/61:35 pm
DSM
- PIT
1 stop8h 10m
United Airlines
Deal found 7/27![United Airlines logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 8/912:09 pm
PIT
- DSM
1 stop12h 10m
Allegiant Air
Do 8/136:00 am
DSM
- PIT
1 stop16h 10m
Allegiant Air
Deal found 7/24![Allegiant Air logo]()
$342
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 10/25:40 am
PIT
- DSM
1 stop8h 40m
Southwest
Mi 10/75:35 am
DSM
- PIT
2 stops6h 20m
Southwest
Deal found 7/25![Southwest logo]()
$343
Best flights from Pittsburgh to Des MoinesDiscover carefully curated flight deals from Pittsburgh to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated Juli 27, 2026.
Discover carefully curated flight deals from Pittsburgh to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated Juli 27, 2026.
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 9/101:50 pm
PIT
- DSM
2 stops9h 25m
Southwest
Mo 9/143:50 pm
DSM
- PIT
1 stop5h 20m
Southwest
Deal found 7/23![Southwest logo]()
$308
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 10/13:45 pm
PIT
- DSM
1 stop6h 52m
American Airlines
Di 10/62:01 pm
DSM
- PIT
1 stop6h 28m
American Airlines
Deal found 7/25![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 10/27:00 am
PIT
- DSM
1 stop4h 31m
United Airlines
Di 10/63:11 pm
DSM
- PIT
1 stop4h 25m
United Airlines
Deal found 7/25![United Airlines logo]()
$338
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 10/36:30 am
PIT
- DSM
1 stop8h 10m
Southwest
Mi 10/75:35 am
DSM
- PIT
2 stops9h 30m
Southwest
Deal found 7/25![Southwest logo]()
$314
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 9/410:45 am
PIT
- DSM
1 stop4h 31m
United Airlines
So 9/65:45 am
DSM
- PIT
1 stop7h 50m
United Airlines
Deal found 7/27![United Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 8/171:50 pm
PIT
- DSM
2 stops9h 20m
Southwest
Do 8/205:40 am
DSM
- PIT
2 stops6h 30m
Southwest
Deal found 7/22![Southwest logo]()
$353
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 9/216:10 pm
PIT
- DSM
1 stop4h 18m
United Airlines
Do 9/2411:27 am
DSM
- PIT
1 stop4h 30m
United Airlines
Deal found 7/23![United Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 10/81:45 pm
PIT
- DSM
1 stop10h 10m
Southwest
So 10/115:30 am
DSM
- PIT
2 stops6h 25m
Southwest
Deal found 7/27![Southwest logo]()
$364
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 9/14:11 pm
PIT
- DSM
1 stop6h 12m
United Airlines
Sa 9/51:21 pm
DSM
- PIT
1 stop6h 26m
United Airlines
Deal found 7/22![United Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 9/41:50 pm
PIT
- DSM
2 stops9h 25m
Southwest
So 9/66:05 am
DSM
- PIT
2 stops11h 25m
Southwest
Deal found 7/27![Southwest logo]()
$385
Last-minute flights from Pittsburgh to Des MoinesDiscover last-minute flight deals from Pittsburgh to Des Moines. Data last updated Juli 27, 2026 and is based on user searches.
Discover last-minute flight deals from Pittsburgh to Des Moines. Data last updated Juli 27, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 8/74:55 pm
PIT
- DSM
1 stop6h 42m
Delta
Di 8/116:00 am
DSM
- PIT
1 stop4h 19m
Delta
Deal found 7/23![Delta logo]()
$477
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 8/77:30 pm
PIT
- DSM
1 stop3h 40m
Southwest
Di 8/117:15 am
DSM
- PIT
2 stops9h 35m
Southwest
Deal found 7/23![Southwest logo]()
$482
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 8/912:09 pm
PIT
- DSM
1 stop12h 10m
Allegiant Air
Do 8/136:00 am
DSM
- PIT
1 stop16h 10m
Allegiant Air
Deal found 7/24![Allegiant Air logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 8/97:49 pm
PIT
- DSM
2 stops22h 28m
Multiple Airlines
Do 8/136:00 am
DSM
- PIT
1 stop16h 10m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$383
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 8/96:16 pm
PIT
- DSM
1 stop5h 40m
United Airlines
Fr 8/141:21 pm
DSM
- PIT
1 stop4h 50m
United Airlines
Deal found 7/24![United Airlines logo]()
$447
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 8/107:30 am
PIT
- DSM
2 stops16h 44m
Allegiant Air
Do 8/136:00 am
DSM
- PIT
1 stop16h 10m
Allegiant Air
Deal found 7/24![Allegiant Air logo]()
$377
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 8/177:30 pm
PIT
- DSM
1 stop3h 40m
Southwest
Do 8/205:40 am
DSM
- PIT
1 stop4h 05m
Southwest
Deal found 7/22![Southwest logo]()
$303
This KAYAK deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 8/175:56 pm
PIT
- DSM
1 stop3h 43m
Delta
Do 8/206:35 pm
DSM
- PIT
1 stop5h 01m
Delta
Deal found 7/26![Delta logo]()
$374
One-way flights from Pittsburgh to Des MoinesSearch for one-way flight options from Pittsburgh to Des Moines. Find affordable one-way fares based on user searches. Data last updated Juli 27, 2026.
Search for one-way flight options from Pittsburgh to Des Moines. Find affordable one-way fares based on user searches. Data last updated Juli 27, 2026.
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 9/36:35 am
PIT
- DSM
1 stop4h 08m
Delta
Deal found 7/27![Delta logo]()
$155
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 9/36:10 am
PIT
- DSM
2 stops9h 06m
United Airlines
Deal found 7/27![United Airlines logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 9/37:10 pm
PIT
- DSM
3 stops27h 58m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$333
Find flight deals from Pittsburgh to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Pittsburgh (PIT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated Juli 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $303 (Southwest) |
One-way from | $155 (Delta) |
Popular in | March |
Cheapest in | October |
Average price | $472 |
Cheapflights Fare Finder
Customize your flight search to find flights from Pittsburgh to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Juli 27, 2026.
Use the filters below to find and compare flights from Pittsburgh to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PittsburghDes Moines
PIT - DSM
PITDSM
Pittsburgh
Do 9/10
1:50 pm-10:15 pm
2 stops9h 25m
Des Moines
Mo 9/14
3:50 pm-10:10 pm
1 stop5h 20m
$308
PittsburghDes Moines
PIT - DSM
PITDSM
Pittsburgh
Do 10/1
3:45 pm-9:37 pm
1 stop6h 52m
Des Moines
Di 10/6
2:01 pm-9:29 pm
1 stop6h 28m
$309
PittsburghDes Moines
PIT - DSM
PITDSM
Pittsburgh
Sa 10/3
6:30 am-1:40 pm
1 stop8h 10m
Des Moines
Mi 10/7
5:35 am-4:05 pm
2 stops9h 30m
$314
PittsburghDes Moines
PIT - DSM
PITDSM
Pittsburgh
Fr 10/2
7:00 am-10:31 am
1 stop4h 31m
Des Moines
Di 10/6
3:11 pm-8:36 pm
1 stop4h 25m
$338
PittsburghDes Moines
PIT - DSM
PITDSM
Pittsburgh
Fr 9/4
10:45 am-2:16 pm
1 stop4h 31m
Des Moines
So 9/6
5:45 am-2:35 pm
1 stop7h 50m
$345
PittsburghDes Moines
PIT - DSM
PITDSM
Pittsburgh
Mo 8/17
1:50 pm-10:10 pm
2 stops9h 20m
Des Moines
Do 8/20
5:40 am-1:10 pm
2 stops6h 30m
$353
Quickest round-trip
PittsburghDes Moines
PIT - DSM
PITDSM
Pittsburgh
Mo 9/21
6:10 pm-9:28 pm
1 stop4h 18m
Des Moines
Do 9/24
11:27 am-4:57 pm
1 stop4h 30m
$363
PittsburghDes Moines
PIT - DSM
PITDSM
Pittsburgh
Do 10/8
1:45 pm-10:55 pm
1 stop10h 10m
Des Moines
So 10/11
5:30 am-12:55 pm
2 stops6h 25m
$364
PittsburghDes Moines
PIT - DSM
PITDSM
Pittsburgh
Di 9/1
4:11 pm-9:23 pm
1 stop6h 12m
Des Moines
Sa 9/5
1:21 pm-8:47 pm
1 stop6h 26m
$383
PittsburghDes Moines
PIT - DSM
PITDSM
Pittsburgh
Fr 9/4
1:50 pm-10:15 pm
2 stops9h 25m
Des Moines
So 9/6
6:05 am-6:30 pm
2 stops11h 25m
$385
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Pittsburgh to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Pittsburgh to Des Moines in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Pittsburgh-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Pittsburgh-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Pittsburgh-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Pittsburgh-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Pittsburgh-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Pittsburgh to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Pittsburgh with our price prediction graph.
PIT-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pittsburgh to Des Moines
What is the cheapest month to book a flight from Pittsburgh to Des Moines?
Currently, October is the cheapest month in which you can book a flight from Pittsburgh to Des Moines (average of $296). Flying from Pittsburgh to Des Moines in March is currently the most expensive (average of $666). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Pittsburgh to Des Moines?
Airfare is below average for this route at the moment.
Pittsburgh to Des Moines flights typically cost between $574 and $812 in August.The cheapest round-trip price found within the last 5 days was $303 on Southwest (Aug 17-Aug 20).
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated Juli 27, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Pittsburgh to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Pittsburgh to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny
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Pittsburgh and Des Moines flights
Browse other Pittsburgh and Des Moines flight options. Last updated on Juli 27, 2026.
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Top 4 airlines flying from Pittsburgh to Des Moines
Discover the top 4 airlines that operate flights from Pittsburgh to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Juli 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$256 | Average$479 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$275 | Average$446 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$281 | Average$386 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$316 | Average$493 | FlexibilityNo cancel fee | On-time63% |