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Des Moines

$295+ Cheap flights from Harrisburg to Des Moines (MDT - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/7. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — DSM
Jul 18 — Jul 251
Sat 7/18
Sat 7/25
1 adult, Economy
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Cheap flight deals from Harrisburg to Des Moines

Cheapest flights from Harrisburg to Des Moines
Explore the most affordable flight options available from Harrisburg to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/711:37 am
MDT
-
DSM
1 stop12h 37m
Allegiant Air
Sun 8/165:12 pm
DSM
-
MDT
1 stop22h 50m
Allegiant Air
Deal found 6/17$295
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:38 pm
MDT
-
DSM
1 stop4h 11m
Delta
Tue 7/215:32 pm
DSM
-
MDT
1 stop4h 37m
Delta
Deal found 6/18$309
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:45 pm
MDT
-
DSM
1 stop5h 16m
American Airlines
Tue 7/211:35 pm
DSM
-
MDT
2 stops7h 35m
American Airlines
Deal found 6/16$314
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:10 pm
MDT
-
DSM
1 stop19h 23m
Allegiant Air
Sun 7/123:59 pm
DSM
-
MDT
1 stop23h 53m
Allegiant Air
Deal found 6/16$341
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:25 am
MDT
-
DSM
1 stop8h 12m
Allegiant Air
Sun 8/95:12 pm
DSM
-
MDT
1 stop22h 50m
Allegiant Air
Deal found 6/13$358
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:34 pm
MDT
-
DSM
1 stop4h 07m
Delta
Sun 7/56:08 am
DSM
-
MDT
1 stop4h 39m
Delta
Deal found 6/16$369
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:25 am
MDT
-
DSM
1 stop8h 12m
Allegiant Air
Sun 8/165:12 pm
DSM
-
MDT
1 stop22h 50m
Allegiant Air
Deal found 6/14$376
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:45 pm
MDT
-
DSM
1 stop5h 16m
American Airlines
Sat 8/810:30 am
DSM
-
MDT
1 stop7h 20m
American Airlines
Deal found 6/17$377
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:15 am
MDT
-
DSM
1 stop5h 19m
American Airlines
Sun 7/125:00 am
DSM
-
MDT
1 stop5h 06m
American Airlines
Deal found 6/15$388

Find flight deals from Harrisburg to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$295
(Kiwi.com)

Popular in

April

Cheapest in

August

Average price

$466
Provider with most accurate pricing for Harrisburg-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Des Moines flights.
Search Deals
From Harrisburg to Des Moines
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($134 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from Harrisburg to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Tue 7/14

7:45 pm-12:01 am

1 stop5h 16m

Des Moines

Tue 7/21

1:35 pm-7:05 pm

1 stop4h 30m

$309

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 8/6

10:25 am-5:37 pm

1 stop8h 12m

Des Moines

Sun 8/9

5:12 pm-5:02 pm

1 stop22h 50m

$358
Quickest round-trip

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Fri 7/3

5:34 pm-8:41 pm

1 stop4h 07m

Des Moines

Sun 7/5

6:08 am-11:47 am

1 stop4h 39m

$369

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Sat 11/14

8:15 am-12:30 pm

1 stop5h 15m

Des Moines

Wed 11/18

1:05 pm-7:30 pm

1 stop5h 25m

$389

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Sat 8/8

5:55 pm-11:00 pm

1 stop6h 05m

Des Moines

Tue 8/11

3:20 pm-8:53 pm

1 stop4h 33m

$389

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Sat 10/31

6:30 am-12:30 pm

1 stop7h 00m

Des Moines

Wed 11/4

3:15 pm-9:20 pm

1 stop5h 05m

$389
Cheapest one-way
Quickest one-way

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Wed 7/15

5:55 pm-10:56 pm

1 stop6h 01m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/17

Sorted by cheapest first

Compare providers for flights from Harrisburg to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Des Moines in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Des Moines

What is the cheapest month to book a flight from Harrisburg to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Harrisburg to Des Moines (average of $308). Flying from Harrisburg to Des Moines in April is currently the most expensive (average of $788). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Harrisburg to Des Moines?

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated June 18, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Harrisburg to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,413 reviews

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.8

Overall

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,413 reviews
Delta
7.8
Good
8,413 reviews

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.8

Overall

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
9,861 reviews
Delta
7.8
Good
8,413 reviews

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.8

Overall

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,691 reviews
Delta
7.8
Good
8,413 reviews

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.8

Overall

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Des Moines?

    American Airlines, Allegiant Air, and Delta can get you from Harrisburg to Des Moines in just under 4h 07m. Your travel time can differ by up to 4h 05m. The distance from Harrisburg to Des Moines is about 886 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Harrisburg to Des Moines round-trip?

    Cheapflights users have booked flights from Harrisburg to Des Moines round-trip from $248. Other airlines that can offer you cheap pricing are United Airlines, from $248, and Delta, from $268. You may be able to fly from Harrisburg to Des Moines for 39% less than the average price by searching for these airlines.

  • Can I find deals for flights from Harrisburg to Des Moines that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Des Moines.

  • Can I find deals for business class flights from Harrisburg to Des Moines?

    Yes. Cheapflights offers flight deals from Harrisburg to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Harrisburg to Des Moines (average of $308). Flying from Harrisburg to Des Moines in April is currently the most expensive (average of $788). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Harrisburg to Des Moines

Discover the top 3 airlines that operate flights from Harrisburg to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$377FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$363FlexibilityNo cancel feeOn-time69%
DeltaCheapest$268Average$378FlexibilityNo cancel feeOn-timeN/A

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