Iowa

$170+ Cheap flights from Harrisburg (MDT) to Iowa

MDT — DSM
Dec 2 — Dec 91
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Cheap flight deals from Harrisburg to Iowa

Cheapest flights from Harrisburg to Iowa

Wed 12/27:02 am -
1 stop7h 22m
Sat 12/51:54 pm -
1 stop7h 34m
Deal found 10/30$321
Sat 12/56:00 am -
1 stop4h 50m
Mon 12/142:58 pm -
1 stop7h 50m
Deal found 11/1$339
Sat 12/56:08 am -
2 stops8h 27m
Mon 12/147:14 am -
1 stop5h 23m
Deal found 10/28$344
Tue 11/176:00 am -
1 stop5h 44m
Thu 11/265:30 am -
1 stop6h 22m
Deal found 10/29$354
Fri 12/116:17 am -
1 stop5h 20m
Sun 12/136:15 am -
2 stops6h 45m
Deal found 10/30$388
Thu 11/1910:30 am -
2 stops7h 58m
Thu 11/266:05 am -
1 stop6h 17m
Deal found 10/29$399
Thu 11/196:00 am -
1 stop4h 44m
Wed 11/252:59 pm -
1 stop7h 51m
Deal found 10/29$409
Wed 12/306:03 am -
1 stop5h 43m
Mon 1/45:00 am -
2 stops8h 00m
Deal found 10/31$411
Tue 11/1712:09 pm -
1 stop5h 40m
Tue 11/245:29 pm -
1 stop4h 37m
Deal found 10/29$424
Thu 12/316:03 am -
1 stop5h 43m
Mon 1/45:00 am -
2 stops8h 00m
Deal found 10/29$429
Sat 11/219:39 am -
2 stops10h 16m
Thu 11/269:31 am -
1 stop5h 34m
Deal found 10/29$433
Sat 11/146:30 am -
1 stop4h 54m
Wed 11/186:00 am -
1 stop6h 24m
Deal found 10/30$469

Find flight deals from Harrisburg to Iowa

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$321
(American Airlines)

One-way from

$170
(American Airlines)

Popular in

April

Cheapest in

November

Average price

$338
Provider with most accurate pricing for Harrisburg-Des Moines flight deals.
Provider most trusted by Cheapflights users for Harrisburg-Des Moines flights.
From Harrisburg to Iowa
One-way flight from Harrisburg to Iowa
Highest demand for flights based on searches. 8% potential increase in price ($49 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($27 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Harrisburg to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HarrisburgCedar Rapids

MDT Harrisburg - CID Cedar Rapids

MDTCID

Harrisburg

Wed 12/2

7:02 am-1:24 pm

1 stop7h 22m

Cedar Rapids

Sat 12/5

1:54 pm-10:28 pm

1 stop7h 34m

$321

HarrisburgDes Moines

MDT Harrisburg - DSM Des Moines

MDTDSM

Harrisburg

Sat 12/5

6:00 am-9:50 am

1 stop4h 50m

Des Moines

Mon 12/14

2:58 pm-11:48 pm

1 stop7h 50m

$339

HarrisburgDes Moines

MDT Harrisburg - DSM Des Moines

MDTDSM

Harrisburg

Fri 12/11

6:17 am-10:37 am

1 stop5h 20m

Des Moines

Sun 12/13

3:20 pm-8:54 pm

1 stop4h 34m

$339

HarrisburgDes Moines

MDT Harrisburg - DSM Des Moines

MDTDSM

Harrisburg

Tue 11/17

6:00 am-10:44 am

1 stop5h 44m

Des Moines

Thu 11/26

5:30 am-12:52 pm

1 stop6h 22m

$354
Quickest round-trip

HarrisburgDes Moines

MDT Harrisburg - DSM Des Moines

MDTDSM

Harrisburg

Sat 11/28

6:00 am-9:44 am

1 stop4h 44m

Des Moines

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$400

HarrisburgDes Moines

MDT Harrisburg - DSM Des Moines

MDTDSM

Harrisburg

Wed 12/30

6:15 am-9:55 am

1 stop4h 40m

Des Moines

Mon 1/4

5:23 pm-11:34 pm

1 stop5h 11m

$409

HarrisburgDes Moines

MDT Harrisburg - DSM Des Moines

MDTDSM

Harrisburg

Wed 12/30

6:03 am-10:46 am

1 stop5h 43m

Des Moines

Mon 1/4

5:00 am-2:00 pm

2 stops8h 00m

$411

HarrisburgCedar Rapids

MDT Harrisburg - CID Cedar Rapids

MDTCID

Harrisburg

Sat 2/6

6:20 am-10:23 am

1 stop5h 03m

Cedar Rapids

Wed 2/10

5:00 am-1:30 pm

1 stop7h 30m

$421

HarrisburgDes Moines

MDT Harrisburg - DSM Des Moines

MDTDSM

Harrisburg

Sun 11/29

12:09 pm-4:49 pm

1 stop5h 40m

Des Moines

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$430

HarrisburgDes Moines

MDT Harrisburg - DSM Des Moines

MDTDSM

Harrisburg

Sat 12/5

9:56 am-7:01 pm

2 stops10h 05m

Des Moines

Mon 12/14

2:05 pm-10:49 pm

2 stops7h 44m

$438

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Best time to book a flight from Harrisburg to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Harrisburg with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Iowa

What is the cheapest month to book a flight from Harrisburg to Iowa?

Currently, July is the cheapest month in which you can book a flight from Harrisburg to Iowa (average of $330). Flying from Harrisburg to Iowa in April is currently the most expensive (average of $771). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Harrisburg to Iowa?

Airfare is typical for this route at the moment.
Harrisburg to Iowa flights typically cost between $318 and $363 in December.
The cheapest round-trip price found within the last 5 days was $339 on Delta (Dec 5-Dec 14).

Reviews of airlines servicing Iowa

Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Harrisburg to Iowa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.8

Food

7.2

Entertainment

7.8

Boarding

8.1

Overall

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Comfort

7.8

Food

7.2

Entertainment

7.8

Boarding

8.1

Overall

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Comfort

7.8

Food

7.2

Entertainment

7.8

Boarding

8.1

Overall

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Comfort

7.8

Food

7.2

Entertainment

7.8

Boarding

8.1

Overall

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Related info for your journey

  • What airport do you fly from for flights from Harrisburg to Iowa?

    For a flight from Harrisburg to Iowa, you will be flying from Harrisburg. Harrisburg (MDT) is just 8.5 mi from the center of the city.

  • How long is the flight from Harrisburg to Iowa?

    Airlines like American Airlines, Delta, and United Airlines fly from Harrisburg to Iowa in about 4h 50m. The time it takes to get you to your destination can typically vary by up to 2h 32m. Harrisburg and Iowa are separated by a distance of 886 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Harrisburg to Iowa?

  • Can I find deals for flights from Harrisburg to Iowa that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Iowa.

  • Can I find deals for business class flights from Harrisburg to Iowa?

    Yes. Cheapflights offers flight deals from Harrisburg to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Iowa?

    Currently, July is the cheapest month in which you can book a flight from Harrisburg to Iowa (average of $330). Flying from Harrisburg to Iowa in April is currently the most expensive (average of $771). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Harrisburg to Iowa

Top 3 airlines flying from Harrisburg to Iowa

AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$252Average$398FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$290Average$509FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$308Average$390FlexibilityNo cancel feeOn-time71%

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