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Des Moines

$119+ Cheap flights from Charleston to Des Moines (CHS - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
jul. 8 — jul. 151
mar. 7/8
mar. 7/15
1 adult, Economy
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Cheap flight deals from Charleston to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated julio 3, 2025.

Round-trip from

$302
(American Airlines)

One-way from

$119
(American Airlines)

Popular in

February

Cheapest in

May

Average price

$335
From Charleston to Des Moines
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One-way flight from Charleston to Des Moines
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Highest demand for flights based on searches. 25% potential increase in price ($152 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($28 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Charleston to Des Moines

Cheapest flights from Charleston to Des Moines
Explore the most affordable flight options available from Charleston to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 3, 2025.

This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/87:38 pmCHS - DSM
1 stop4h 20mAmerican Airlines
mar. 8/125:29 pmDSM - CHS
1 stop4h 34mAmerican Airlines
Deal found 7/1$302
This Mytrip deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/1710:53 amCHS - DSM
3 stops32h 13mMultiple Airlines
lun. 7/216:30 amDSM - CHS
1 stop7h 15mMultiple Airlines
Deal found 7/2$321
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/14:15 pmCHS - DSM
2 stops8h 35mSouthwest
vie. 8/86:00 amDSM - CHS
1 stop3h 45mSouthwest
Deal found 7/2$364
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/154:27 pmCHS - DSM
1 stop8h 32mUnited Airlines
mié. 7/168:00 amDSM - CHS
1 stop5h 02mUnited Airlines
Deal found 7/1$422

Cheapflights Fare Finder

Customize your flight search to find flights from Charleston to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
Use the filters below to find and compare flights from Charleston to Des Moines that are best for you.

Fly from

Charleston

Fly to

Des Moines

Route

Depart

Return

Price

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

vie. 8/8

7:38 pm-10:58 pm

1 stop4h 20m

Des Moines

mar. 8/12

5:29 pm-11:03 pm

1 stop4h 34m

$302

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

jue. 7/17

10:53 am-6:06 pm

3 stops32h 13m

Des Moines

lun. 7/21

6:30 am-2:45 pm

1 stop7h 15m

$321

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

vie. 8/1

5:00 pm-11:50 pm

1 stop7h 50m

Des Moines

vie. 8/8

6:00 am-10:45 am

1 stop3h 45m

$364

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

mar. 7/15

4:27 pm-11:59 pm

1 stop8h 32m

Des Moines

mié. 7/16

8:00 am-2:02 pm

1 stop5h 02m

$422

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

mar. 10/7

1:42 pm-8:11 pm

1 stop7h 29m

$119

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

jue. 8/7

2:28 pm-8:49 am

2 stops19h 21m

$173

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

mar. 10/7

7:47 pm-9:50 pm

3 stops27h 03m

$313

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Charleston to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Des Moines

What is the cheapest month to book a flight from Charleston to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Charleston to Des Moines (average of $336). Flying from Charleston to Des Moines in June is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to DSM?

Find hourly flight availability from Charleston to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 3, 2025.

When flying from Charleston to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 16% versus a flight at noon.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated julio 3, 2025.
Get a feel of what it's like to fly with Southwest, United Airlines, and American Airlines from Charleston to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,266 reviews

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,266 reviews
Southwest
8.0
Very good
4,266 reviews

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,861 reviews
Southwest
8.0
Very good
4,266 reviews

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,266 reviews

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Charleston to Des Moines round-trip?

    Currently priced at $302, American Airlines will fly you from Charleston to Des Moines and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Southwest and United Airlines - these airlines can fly you to your destination from $364 and $422, respectively. American Airlines is 33% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Charleston to Des Moines that include hotel bookings?

    Yes. In addition to deals on Charleston to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Des Moines.

  • Can I find deals for business class flights from Charleston to Des Moines?

    Yes. Cheapflights offers flight deals from Charleston to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Charleston to Des Moines (average of $336). Flying from Charleston to Des Moines in June is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Altoona
Ames
Johnston
Boone
West Des Moines
Ankeny

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Top 2 airlines flying from Charleston to Des Moines

Discover the top 2 airlines that operate flights from Charleston to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$258Average$372FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$270Average$536FlexibilityNo cancel feeOn-time71%

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