$307+ Cheap flights from Columbia to Des Moines (CAE - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/4. Fares are subject to change and may not be available on all flights or dates of travel.
CAE — DSM
Oct 14 — Oct 211
Round-trip
1 adult, Economy
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Find cheap flights from Columbia to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbia to Des Moines
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Best
Last-minute
One-way
Cheapest flights from Columbia to Des MoinesExplore the most affordable flight options available from Columbia to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
Explore the most affordable flight options available from Columbia to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:40 am -
1 stop6h 02m
Mon 11/92:59 pm -
1 stop5h 42m
Deal found 9/10![Delta logo]()
$307
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:18 am -
1 stop4h 46m
Mon 9/282:13 pm -
1 stop7h 46m
Deal found 9/9![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:59 pm -
1 stop5h 10m
Sun 11/15:39 am -
1 stop4h 09m
Deal found 9/10![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:21 pm -
2 stops10h 34m
Sat 10/313:15 pm -
1 stop4h 47m
Deal found 9/13![United Airlines logo]()
$412
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:19 pm -
1 stop4h 07m
Sun 9/206:54 pm -
1 stop3h 55m
Deal found 9/9![Delta logo]()
$424
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:45 pm -
2 stops8h 34m
Mon 11/93:31 pm -
1 stop6h 54m
Deal found 9/10![American Airlines logo]()
$427
Best flights from Columbia to Des MoinesDiscover carefully curated flight deals from Columbia to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
Discover carefully curated flight deals from Columbia to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:40 am -
1 stop6h 02m
Mon 11/92:59 pm -
1 stop5h 42m
Deal found 9/10![Delta logo]()
$307
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:18 am -
1 stop4h 46m
Mon 9/282:13 pm -
1 stop7h 46m
Deal found 9/9![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:21 pm -
2 stops10h 34m
Sat 10/313:15 pm -
1 stop4h 47m
Deal found 9/13![United Airlines logo]()
$412
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:45 pm -
2 stops8h 34m
Mon 11/93:31 pm -
1 stop6h 54m
Deal found 9/10![American Airlines logo]()
$427
Last-minute flights from Columbia to Des MoinesDiscover last-minute flight deals from Columbia to Des Moines. Data last updated September 14, 2026 and is based on user searches.
Discover last-minute flight deals from Columbia to Des Moines. Data last updated September 14, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:19 pm -
1 stop4h 07m
Sun 9/206:54 pm -
1 stop3h 55m
Deal found 9/9![Delta logo]()
$424
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:47 pm -
1 stop5h 54m
Sun 9/205:57 pm -
1 stop5h 06m
Deal found 9/12![American Airlines logo]()
$446
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:18 am -
1 stop4h 46m
Mon 9/282:13 pm -
1 stop7h 46m
Deal found 9/9![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:21 pm -
2 stops10h 34m
Sat 10/313:15 pm -
1 stop4h 47m
Deal found 9/13![United Airlines logo]()
$412
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:59 pm -
1 stop5h 10m
Sun 11/15:39 am -
1 stop4h 09m
Deal found 9/10![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:33 pm -
2 stops8h 47m
Sun 11/17:06 am -
1 stop4h 11m
Deal found 9/10![American Airlines logo]()
$477
One-way flights from Columbia to Des MoinesSearch for one-way flight options from Columbia to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
Search for one-way flight options from Columbia to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:38 pm -
1 stop6h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:00 am -
1 stop4h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$424
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2110:22 am -
2 stops12h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:15 am -
1 stop18h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![United Airlines logo]()
$472
Find flight deals from Columbia to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Columbia (CAE) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $307 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbia to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
Use the filters below to find and compare flights from Columbia to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbiaDes Moines
CAE Columbia Metropolitan - DSM Des Moines
CAEDSM
Columbia Metropolitan
Wed 11/4
5:40 am-10:42 am
1 stop6h 02m
Des Moines
Mon 11/9
2:59 pm-9:41 pm
1 stop5h 42m
$307
ColumbiaDes Moines
CAE Columbia Metropolitan - DSM Des Moines
CAEDSM
Columbia Metropolitan
Thu 9/24
8:18 am-12:04 pm
1 stop4h 46m
Des Moines
Mon 9/28
2:13 pm-10:59 pm
1 stop7h 46m
$349
ColumbiaDes Moines
CAE Columbia Metropolitan - DSM Des Moines
CAEDSM
Columbia Metropolitan
Fri 9/25
11:57 am-6:09 pm
1 stop7h 12m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$369
Quickest round-trip
ColumbiaDes Moines
CAE Columbia Metropolitan - DSM Des Moines
CAEDSM
Columbia Metropolitan
Fri 9/25
5:38 pm-11:35 pm
1 stop6h 57m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$369
ColumbiaDes Moines
CAE Columbia Metropolitan - DSM Des Moines
CAEDSM
Columbia Metropolitan
Wed 10/28
12:21 pm-9:55 pm
2 stops10h 34m
Des Moines
Sat 10/31
3:15 pm-9:02 pm
1 stop4h 47m
$412
ColumbiaDes Moines
CAE Columbia Metropolitan - DSM Des Moines
CAEDSM
Columbia Metropolitan
Wed 11/4
1:45 pm-9:19 pm
2 stops8h 34m
Des Moines
Mon 11/9
3:31 pm-11:25 pm
1 stop6h 54m
$427
ColumbiaDes Moines
CAE Columbia Metropolitan - DSM Des Moines
CAEDSM
Columbia Metropolitan
Mon 9/21
10:22 am-9:28 pm
2 stops12h 06m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$429
Sorted by cheapest first
Compare providers for flights from Columbia to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbia to Des Moines in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Columbia-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbia-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbia-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Columbia-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbia-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Columbia to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Columbia with our price prediction graph.
CAE-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 14, 2026.
See what other customers who have flown with Delta and American Airlines from Columbia to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Entertainment
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Entertainment
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Entertainment
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Columbia to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Columbia and Des Moines flights
Browse other Columbia and Des Moines flight options. Last updated on September 14, 2026.
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Top 2 airlines flying from Columbia to Des Moines
Discover the top 2 airlines that operate flights from Columbia to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$268 | Average$469 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$294 | Average$328 | FlexibilityNo cancel fee | On-timeN/A |