$146+ Cheap flights from Milwaukee to Des Moines (MKE - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — DSM
Oct 20 — Oct 271
Round-trip
1 adult, Economy
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Find cheap flights from Milwaukee to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Milwaukee to Des Moines
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Best
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One-way
Cheapest flights from Milwaukee to Des MoinesExplore the most affordable flight options available from Milwaukee to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
Explore the most affordable flight options available from Milwaukee to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:00 pm -
1 stop5h 00m
Sat 11/74:01 pm -
1 stop5h 12m
Deal found 9/15![Delta logo]()
$209
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:50 pm -
1 stop6h 15m
Wed 11/116:00 am -
1 stop5h 00m
Deal found 9/17![Southwest logo]()
$223
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:50 pm -
1 stop6h 15m
Thu 11/125:25 am -
1 stop5h 35m
Deal found 9/17![Southwest logo]()
$237
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:00 am -
2 stops14h 05m
Mon 12/76:00 am -
1 stop5h 00m
Deal found 9/17![Southwest logo]()
$248
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:50 pm -
1 stop6h 10m
Mon 11/24:25 pm -
1 stop5h 45m
Deal found 9/16![Southwest logo]()
$277
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:32 pm -
1 stop5h 03m
Wed 10/2111:27 am -
1 stop3h 44m
Deal found 9/16![United Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:30 am -
1 stop3h 41m
Thu 10/226:55 am -
1 stop3h 14m
Deal found 9/17![Delta logo]()
$291
Best flights from Milwaukee to Des MoinesDiscover carefully curated flight deals from Milwaukee to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
Discover carefully curated flight deals from Milwaukee to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/34:15 pm -
1 stop5h 50m
Mon 12/76:00 am -
1 stop5h 00m
Deal found 9/17![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:32 pm -
1 stop5h 03m
Wed 10/216:00 am -
1 stop4h 07m
Deal found 9/15![United Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:30 am -
1 stop3h 41m
Sun 10/186:55 am -
1 stop3h 14m
Deal found 9/16![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:30 am -
1 stop6h 00m
Mon 11/24:25 pm -
2 stops6h 40m
Deal found 9/16![Southwest logo]()
$282
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:00 am -
1 stop4h 19m
Mon 11/306:45 pm -
1 stop3h 30m
Deal found 9/19![United Airlines logo]()
$312
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:33 pm -
1 stop6h 22m
Mon 11/306:45 pm -
1 stop3h 30m
Deal found 9/19![United Airlines logo]()
$317
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:18 pm -
1 stop3h 37m
Wed 11/118:00 am -
1 stop5h 32m
Deal found 9/19![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:45 am -
2 stops14h 05m
Mon 11/305:10 am -
2 stops10h 20m
Deal found 9/19![Southwest logo]()
$410
Last-minute flights from Milwaukee to Des MoinesDiscover last-minute flight deals from Milwaukee to Des Moines. Data last updated September 20, 2026 and is based on user searches.
Discover last-minute flight deals from Milwaukee to Des Moines. Data last updated September 20, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:30 am -
1 stop5h 45m
Mon 10/56:55 pm -
1 stop4h 04m
Deal found 9/16![United Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:15 am -
2 stops14h 55m
Mon 10/54:30 pm -
1 stop6h 05m
Deal found 9/16![Southwest logo]()
$429
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:20 pm -
1 stop3h 28m
Tue 10/63:11 pm -
1 stop3h 59m
Deal found 9/17![United Airlines logo]()
$384
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:15 am -
2 stops14h 55m
Tue 10/65:35 am -
1 stop5h 30m
Deal found 9/17![Southwest logo]()
$408
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:30 am -
1 stop7h 50m
Fri 10/94:30 pm -
2 stops7h 50m
Deal found 9/20![Southwest logo]()
$482
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:30 am -
1 stop3h 41m
Thu 10/226:55 am -
1 stop3h 14m
Deal found 9/17![Delta logo]()
$291
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:30 am -
1 stop3h 41m
Sun 10/186:55 am -
1 stop3h 14m
Deal found 9/16![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:15 am -
2 stops15h 00m
Sun 10/185:30 am -
1 stop5h 20m
Deal found 9/16![Southwest logo]()
$443
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:32 pm -
1 stop5h 03m
Wed 10/216:00 am -
1 stop4h 07m
Deal found 9/15![United Airlines logo]()
$279
One-way flights from Milwaukee to Des MoinesSearch for one-way flight options from Milwaukee to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 20, 2026.
Search for one-way flight options from Milwaukee to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 20, 2026.
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:52 pm -
1 stop5h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![United Airlines logo]()
$146
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:30 am -
1 stop3h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Delta logo]()
$149
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:55 am -
2 stops14h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Southwest logo]()
$160
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:20 am -
2 stops13h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Southwest logo]()
$190
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:23 pm -
3 stops25h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![United Airlines logo]()
$400
Find flight deals from Milwaukee to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Milwaukee (MKE) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $209 (Delta) |
One-way from | $146 (United Airlines) |
Popular in | July |
Cheapest in | December |
Cheapflights Fare Finder
Customize your flight search to find flights from Milwaukee to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 20, 2026.
Use the filters below to find and compare flights from Milwaukee to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Tue 10/13
3:52 pm-9:23 pm
1 stop5h 31m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$146
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Fri 11/6
7:55 am-10:05 pm
2 stops14h 10m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$160
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Tue 10/13
8:20 am-10:00 pm
2 stops13h 40m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$190
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Thu 12/3
4:15 pm-10:05 pm
1 stop5h 50m
Des Moines
Mon 12/7
6:00 am-11:00 am
1 stop5h 00m
$237
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Tue 10/20
6:32 pm-11:35 pm
1 stop5h 03m
Des Moines
Wed 10/21
6:00 am-10:07 am
1 stop4h 07m
$279
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Sun 11/1
5:30 am-11:30 am
1 stop6h 00m
Des Moines
Mon 11/2
4:25 pm-11:05 pm
2 stops6h 40m
$282
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Sat 11/21
8:00 am-12:19 pm
1 stop4h 19m
Des Moines
Mon 11/30
6:45 pm-10:15 pm
1 stop3h 30m
$312
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Fri 10/16
6:30 am-10:11 am
1 stop3h 41m
Des Moines
Sun 10/18
6:55 am-10:09 am
1 stop3h 14m
$317
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Wed 11/25
3:33 pm-9:55 pm
1 stop6h 22m
Des Moines
Mon 11/30
6:45 pm-10:15 pm
1 stop3h 30m
$317
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Mon 11/9
6:18 pm-9:55 pm
1 stop3h 37m
Des Moines
Wed 11/11
8:00 am-1:32 pm
1 stop5h 32m
$339
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Milwaukee to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Milwaukee to Des Moines in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Milwaukee-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Milwaukee-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Milwaukee-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Milwaukee-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Milwaukee-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Milwaukee to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Milwaukee with our price prediction graph.
MKE-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Milwaukee to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
West Des Moines
Boone
Norwalk
Ankeny
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