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Des Moines

$122+ Cheap flights from Milwaukee to Des Moines (MKE - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — DSM
Jul 22 — Jul 291
Wed 7/22
Wed 7/29
1 adult, Economy
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Cheap flight deals from Milwaukee to Des Moines

Cheapest flights from Milwaukee to Des Moines
Explore the most affordable flight options available from Milwaukee to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 22, 2026.

This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:02 am
MKE
-
DSM
1 stop3h 21m
American Airlines
Tue 7/288:53 am
DSM
-
MKE
1 stop3h 52m
American Airlines
Deal found 6/19$243
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/184:57 pm
MKE
-
DSM
1 stop3h 52m
Delta
Tue 7/215:52 pm
DSM
-
MKE
1 stop3h 49m
Delta
Deal found 6/17$275
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1510:15 am
MKE
-
DSM
2 stops12h 35m
Southwest
Wed 7/223:45 pm
DSM
-
MKE
1 stop6h 10m
Southwest
Deal found 6/17$282
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:30 am
MKE
-
DSM
1 stop3h 48m
Delta
Sun 9/611:00 am
DSM
-
MKE
1 stop3h 15m
Delta
Deal found 6/17$289
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:43 am
MKE
-
DSM
1 stop4h 21m
American Airlines
Fri 7/246:33 pm
DSM
-
MKE
1 stop3h 48m
American Airlines
Deal found 6/17$307
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:50 am
MKE
-
DSM
1 stop4h 46m
United Airlines
Wed 11/1811:31 am
DSM
-
MKE
1 stop3h 27m
United Airlines
Deal found 6/20$308
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/165:15 am
MKE
-
DSM
1 stop7h 35m
Southwest
Thu 7/235:10 am
DSM
-
MKE
1 stop5h 55m
Southwest
Deal found 6/18$327
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:40 am
MKE
-
DSM
1 stop5h 40m
Southwest
Sun 11/295:20 am
DSM
-
MKE
1 stop6h 40m
Southwest
Deal found 6/18$342
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:25 am
MKE
-
DSM
2 stops13h 10m
Southwest
Thu 7/234:40 pm
DSM
-
MKE
1 stop6h 10m
Southwest
Deal found 6/18$358
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/228:05 am
MKE
-
DSM
2 stops14h 45m
Southwest
Tue 7/283:45 pm
DSM
-
MKE
1 stop6h 10m
Southwest
Deal found 6/19$361

Find flight deals from Milwaukee to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Milwaukee (MKE) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$243
(American Airlines)

One-way from

$122
(Southwest)

Popular in

April

Cheapest in

August

Average price

$506
Provider with most accurate pricing for Milwaukee-Mitchell-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Milwaukee-Mitchell-Des Moines flights.
Search Deals
From Milwaukee-Mitchell to Des Moines
Search Deals
One-way flight from Milwaukee-Mitchell to Des Moines
Search Deals
Highest demand for flights based on searches. 28% potential increase in price ($135 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Milwaukee to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 22, 2026.
Use the filters below to find and compare flights from Milwaukee to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Wed 7/15

10:15 am-10:50 pm

2 stops12h 35m

Des Moines

Wed 7/22

3:45 pm-9:55 pm

1 stop6h 10m

$282
Quickest round-trip

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sat 9/5

6:30 am-10:18 am

1 stop3h 48m

Des Moines

Sun 9/6

11:00 am-2:15 pm

1 stop3h 15m

$289

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 7/23

5:00 am-10:17 am

1 stop5h 17m

Des Moines

Sun 7/26

6:50 pm-10:29 pm

1 stop3h 39m

$307

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Tue 11/17

7:50 am-12:36 pm

1 stop4h 46m

Des Moines

Wed 11/18

11:31 am-2:58 pm

1 stop3h 27m

$308

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Wed 7/22

8:05 am-10:50 pm

2 stops14h 45m

Des Moines

Tue 7/28

3:45 pm-9:55 pm

1 stop6h 10m

$361

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Fri 7/17

10:25 am-11:35 pm

2 stops13h 10m

Des Moines

Fri 7/24

4:40 pm-10:50 pm

1 stop6h 10m

$368

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 7/23

7:20 am-11:35 pm

2 stops16h 15m

Des Moines

Sun 7/26

4:15 pm-11:15 pm

1 stop7h 00m

$374

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Fri 7/3

8:50 am-2:27 pm

1 stop5h 37m

Des Moines

Fri 7/10

3:24 pm-7:26 pm

1 stop4h 02m

$397

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Wed 11/25

7:55 am-11:25 pm

2 stops15h 30m

Des Moines

Sun 11/29

6:10 pm-12:05 am

2 stops5h 55m

$401
Cheapest one-way

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Wed 8/19

8:20 am-9:55 pm

2 stops13h 35m

$133

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/18

Showing 1-10 of 21 resultsSorted by cheapest first
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Compare providers for flights from Milwaukee to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Milwaukee to Des Moines in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Milwaukee-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Milwaukee-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Milwaukee-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Milwaukee-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Milwaukee-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Milwaukee to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Milwaukee to Des Moines?

    Airlines like Southwest, Delta, and United Airlines fly from Milwaukee to Des Moines in about 3h 48m. The time it takes to get you to your destination can typically vary by up to 8h 47m. There are 310 mi between Milwaukee and Des Moines. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Milwaukee to Des Moines that include hotel bookings?

    Yes. In addition to deals on Milwaukee to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to Des Moines.

  • Can I find deals for business class flights from Milwaukee to Des Moines?

    Yes. Cheapflights offers flight deals from Milwaukee to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny

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