$125+ Cheap flights from Milwaukee to Des Moines (MKE - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — DSM
Dec 5 — Dec 121
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Milwaukee to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Milwaukee to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Milwaukee to Des MoinesExplore the most affordable flight options available from Milwaukee to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Milwaukee to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:00 am -
1 stop5h 37m
Wed 12/166:15 am -
1 stop3h 48m
Deal found 11/4![United Airlines logo]()
$244
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/314:20 pm -
1 stop5h 45m
Thu 1/213:00 pm -
1 stop5h 30m
Deal found 11/2![Southwest logo]()
$249
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:45 pm -
1 stop4h 34m
Sat 11/287:11 am -
1 stop5h 05m
Deal found 10/31![American Airlines logo]()
$313
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:50 am -
1 stop7h 20m
Wed 12/166:00 am -
2 stops15h 30m
Deal found 11/4![Southwest logo]()
$333
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:00 am -
1 stop5h 37m
Thu 12/36:15 am -
1 stop3h 48m
Deal found 11/3![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:00 am -
1 stop3h 51m
Mon 12/289:53 am -
1 stop23h 31m
Deal found 11/1![American Airlines logo]()
$342
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:10 pm -
2 stops6h 25m
Sat 11/285:20 am -
1 stop5h 40m
Deal found 10/31![Southwest logo]()
$412
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:44 pm -
1 stop6h 31m
Sun 11/2211:00 am -
1 stop4h 19m
Deal found 11/3![Delta logo]()
$497
Best flights from Milwaukee to Des MoinesDiscover carefully curated flight deals from Milwaukee to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Milwaukee to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:00 am -
1 stop5h 37m
Wed 12/166:15 am -
1 stop3h 48m
Deal found 11/4![United Airlines logo]()
$244
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/314:20 pm -
1 stop5h 45m
Thu 1/213:00 pm -
1 stop5h 30m
Deal found 11/2![Southwest logo]()
$249
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/46:26 am -
1 stop3h 48m
Fri 1/810:54 am -
1 stop5h 50m
Deal found 11/2![Delta logo]()
$283
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:45 pm -
1 stop4h 34m
Sat 11/287:11 am -
1 stop5h 05m
Deal found 10/31![American Airlines logo]()
$313
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:50 am -
1 stop7h 20m
Wed 12/166:00 am -
2 stops15h 30m
Deal found 11/4![Southwest logo]()
$333
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:00 am -
1 stop5h 37m
Thu 12/36:15 am -
1 stop3h 48m
Deal found 11/4![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/86:45 am -
1 stop3h 35m
Sun 4/117:00 am -
1 stop3h 02m
Deal found 11/5![Delta logo]()
$347
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:00 am -
1 stop3h 51m
Mon 12/289:53 am -
1 stop6h 31m
Deal found 11/4![American Airlines logo]()
$378
Last-minute flights from Milwaukee to Des MoinesDiscover last-minute flight deals from Milwaukee to Des Moines. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Milwaukee to Des Moines. Data last updated November 5, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:44 pm -
1 stop6h 31m
Sun 11/2211:00 am -
1 stop4h 19m
Deal found 11/3![Delta logo]()
$497
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:45 pm -
1 stop4h 34m
Sat 11/287:11 am -
1 stop5h 05m
Deal found 10/31![American Airlines logo]()
$313
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:10 pm -
2 stops6h 25m
Sat 11/285:20 am -
1 stop5h 40m
Deal found 10/31![Southwest logo]()
$412
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:00 am -
1 stop5h 37m
Thu 12/36:15 am -
1 stop3h 48m
Deal found 11/3![United Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:00 am -
1 stop5h 37m
Wed 12/166:15 am -
1 stop3h 48m
Deal found 11/4![United Airlines logo]()
$244
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:50 am -
1 stop7h 20m
Wed 12/166:00 am -
2 stops15h 30m
Deal found 11/4![Southwest logo]()
$333
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:00 am -
1 stop3h 51m
Mon 12/289:53 am -
1 stop23h 31m
Deal found 11/1![American Airlines logo]()
$342
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/314:20 pm -
1 stop5h 45m
Thu 1/213:00 pm -
1 stop5h 30m
Deal found 11/2![Southwest logo]()
$249
One-way flights from Milwaukee to Des MoinesSearch for one-way flight options from Milwaukee to Des Moines. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from Milwaukee to Des Moines. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:00 am -
1 stop4h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$125
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:55 am -
2 stops15h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Southwest logo]()
$205
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:00 am -
1 stop5h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![United Airlines logo]()
$249
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:55 pm -
1 stop3h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![American Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/224:05 pm -
2 stops7h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Southwest logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:11 pm -
3 stops41h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$361
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:30 pm -
3 stops51h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$371
Find flight deals from Milwaukee to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Milwaukee (MKE) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $244 (United Airlines) |
One-way from | $125 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Milwaukee to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Milwaukee to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Wed 11/25
5:00 am-9:00 am
1 stop4h 00m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$125
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Wed 11/25
7:55 am-11:35 pm
2 stops15h 40m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$205
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Fri 12/11
5:00 am-10:37 am
1 stop5h 37m
Des Moines
Wed 12/16
6:15 am-10:03 am
1 stop3h 48m
$244
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Sun 11/22
5:00 am-10:32 am
1 stop5h 32m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$249
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Thu 12/31
4:20 pm-10:05 pm
1 stop5h 45m
Des Moines
Thu 1/21
3:00 pm-8:30 pm
1 stop5h 30m
$249
Quickest round-trip
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Sun 11/22
2:55 pm-6:54 pm
1 stop3h 59m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$254
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Sun 11/22
4:05 pm-11:05 pm
2 stops7h 00m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$259
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Mon 1/4
6:26 am-10:14 am
1 stop3h 48m
Des Moines
Fri 1/8
10:54 am-4:44 pm
1 stop5h 50m
$283
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Wed 11/25
7:45 pm-12:19 am
1 stop4h 34m
Des Moines
Sat 11/28
7:11 am-12:16 pm
1 stop5h 05m
$313
MilwaukeeDes Moines
MKE Milwaukee-Mitchell - DSM Des Moines
MKEDSM
Milwaukee-Mitchell
Fri 12/11
5:50 am-1:10 pm
1 stop7h 20m
Des Moines
Wed 12/16
6:00 am-9:30 pm
2 stops15h 30m
$333
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Milwaukee to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Milwaukee to Des Moines in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Milwaukee-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Milwaukee-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Milwaukee-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Milwaukee-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Milwaukee-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Milwaukee to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Milwaukee with our price prediction graph.
MKE-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated November 5, 2026.
See what other customers who have flown with United Airlines from Milwaukee to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Boarding
7.7
Crew
8.1
Comfort
7.3
Entertainment
7.1
Overall
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Food
6.7
Boarding
7.7
Crew
8.1
Comfort
7.3
Entertainment
7.1
Overall
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Milwaukee to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Des Moines flight routes
Flights by cabin class
Other flight options
Other flights from Milwaukee
Popular flights
Alternative routes for Milwaukee to Des Moines
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 5, 2026.
Search flights from Milwaukee to Des Moines by cabin class
Find flights from Milwaukee to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Milwaukee and Des Moines flights
Browse other Milwaukee and Des Moines flight options. Last updated on November 5, 2026.
Other flights from Milwaukee
Browse through other flights departing from Milwaukee. Flights are based on user searches made on Cheapflights and were last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Milwaukee to Des Moines
Discover the top airline that operate flights from Milwaukee to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$263 | Average$476 | FlexibilityNo cancel fee | On-time69% |