$309+ Cheap flights from Madison to Des Moines (MSN - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
MSN — DSM
Nov 9 — Nov 161
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Madison to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Madison to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Madison to Des MoinesExplore the most affordable flight options available from Madison to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 10, 2026.
Explore the most affordable flight options available from Madison to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 10, 2026.
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:00 am -
1 stop3h 56m
Sun 11/17:26 pm -
1 stop4h 47m
Deal found 10/8![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:49 am -
1 stop5h 45m
Sun 10/256:45 pm -
1 stop4h 22m
Deal found 10/6![United Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:52 pm -
1 stop6h 03m
Tue 11/106:45 pm -
1 stop4h 22m
Deal found 10/7![United Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/183:47 pm -
1 stop5h 36m
Wed 12/235:30 am -
1 stop7h 52m
Deal found 10/8![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:35 pm -
1 stop5h 00m
Sat 10/241:26 pm -
1 stop3h 48m
Deal found 10/5![United Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
1 stop4h 11m
Fri 10/237:51 pm -
1 stop23h 15m
Deal found 10/5![Delta logo]()
$523
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:59 am -
1 stop6h 26m
Fri 10/237:51 pm -
1 stop23h 15m
Deal found 10/5![Delta logo]()
$533
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:05 pm -
1 stop5h 09m
Fri 10/307:29 am -
1 stop3h 23m
Deal found 10/9![American Airlines logo]()
$542
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:38 am -
2 stops28h 04m
Fri 10/233:04 pm -
1 stop25h 14m
Deal found 10/5![Multiple Airlines logo]()
$545
Best flights from Madison to Des MoinesDiscover carefully curated flight deals from Madison to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 10, 2026.
Discover carefully curated flight deals from Madison to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 10, 2026.
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:49 pm -
1 stop6h 34m
Tue 10/278:00 am -
1 stop3h 49m
Deal found 10/8![United Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:49 am -
1 stop5h 45m
Sun 10/256:45 pm -
1 stop4h 22m
Deal found 10/6![United Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:52 pm -
1 stop6h 03m
Tue 11/106:45 pm -
1 stop4h 22m
Deal found 10/7![United Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/183:47 pm -
1 stop5h 36m
Wed 12/235:30 am -
1 stop7h 52m
Deal found 10/8![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:35 pm -
1 stop5h 00m
Sat 10/241:26 pm -
1 stop3h 48m
Deal found 10/5![United Airlines logo]()
$429
Last-minute flights from Madison to Des MoinesDiscover last-minute flight deals from Madison to Des Moines. Data last updated October 10, 2026 and is based on user searches.
Discover last-minute flight deals from Madison to Des Moines. Data last updated October 10, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:59 am -
1 stop6h 26m
Fri 10/237:51 pm -
1 stop23h 15m
Deal found 10/5![Delta logo]()
$533
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
1 stop4h 11m
Fri 10/237:51 pm -
1 stop23h 15m
Deal found 10/5![Delta logo]()
$523
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:35 pm -
1 stop5h 00m
Sat 10/241:26 pm -
1 stop3h 48m
Deal found 10/5![United Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:49 am -
1 stop5h 45m
Sun 10/256:45 pm -
1 stop4h 22m
Deal found 10/6![United Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:38 am -
2 stops28h 04m
Fri 10/233:04 pm -
1 stop25h 14m
Deal found 10/5![Multiple Airlines logo]()
$545
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:00 am -
1 stop5h 31m
Wed 10/211:24 pm -
1 stop3h 44m
Deal found 10/5![United Airlines logo]()
$591
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:05 pm -
1 stop5h 09m
Fri 10/307:29 am -
1 stop3h 23m
Deal found 10/9![American Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:00 am -
1 stop3h 56m
Sun 11/17:26 pm -
1 stop4h 47m
Deal found 10/8![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:52 pm -
1 stop6h 03m
Tue 11/106:45 pm -
1 stop4h 22m
Deal found 10/7![United Airlines logo]()
$347
One-way flights from Madison to Des MoinesSearch for one-way flight options from Madison to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 10, 2026.
Search for one-way flight options from Madison to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 10, 2026.
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:28 pm -
1 stop3h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![American Airlines logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:30 am -
3 stops52h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Multiple Airlines logo]()
$542
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:06 am -
2 stops8h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![United Airlines logo]()
$871
Find flight deals from Madison to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Madison (MSN) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (American Airlines) |
Popular in | September |
Cheapest in | November |
Average price | $308 |
Cheapflights Fare Finder
Customize your flight search to find flights from Madison to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 10, 2026.
Use the filters below to find and compare flights from Madison to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MadisonDes Moines
MSN Madison Truax Field - DSM Des Moines
MSNDSM
Madison Truax Field
Fri 10/23
2:49 pm-9:23 pm
1 stop6h 34m
Des Moines
Tue 10/27
8:00 am-11:49 am
1 stop3h 49m
$339
MadisonDes Moines
MSN Madison Truax Field - DSM Des Moines
MSNDSM
Madison Truax Field
Wed 10/21
6:49 am-12:34 pm
1 stop5h 45m
Des Moines
Sun 10/25
6:45 pm-11:07 pm
1 stop4h 22m
$339
MadisonDes Moines
MSN Madison Truax Field - DSM Des Moines
MSNDSM
Madison Truax Field
Sat 11/7
3:52 pm-9:55 pm
1 stop6h 03m
Des Moines
Tue 11/10
6:45 pm-11:07 pm
1 stop4h 22m
$347
Quickest round-trip
MadisonDes Moines
MSN Madison Truax Field - DSM Des Moines
MSNDSM
Madison Truax Field
Tue 10/13
3:28 pm-7:00 pm
1 stop3h 32m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$379
MadisonDes Moines
MSN Madison Truax Field - DSM Des Moines
MSNDSM
Madison Truax Field
Fri 12/18
3:47 pm-9:23 pm
1 stop5h 36m
Des Moines
Wed 12/23
5:30 am-1:22 pm
1 stop7h 52m
$399
MadisonDes Moines
MSN Madison Truax Field - DSM Des Moines
MSNDSM
Madison Truax Field
Tue 10/20
6:35 pm-11:35 pm
1 stop5h 00m
Des Moines
Sat 10/24
1:26 pm-5:14 pm
1 stop3h 48m
$429
MadisonDes Moines
MSN Madison Truax Field - DSM Des Moines
MSNDSM
Madison Truax Field
Tue 10/13
10:30 am-2:42 pm
3 stops52h 12m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$542
MadisonDes Moines
MSN Madison Truax Field - DSM Des Moines
MSNDSM
Madison Truax Field
Tue 10/13
6:06 am-2:15 pm
2 stops8h 09m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$871
Sorted by cheapest first
Compare providers for flights from Madison to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Madison to Des Moines in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Madison-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Madison-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Madison-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Madison-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Madison-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Madison to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Madison with our price prediction graph.
MSN-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madison to Des Moines
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 10, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Madison to Des Moines by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Overall
7.4
Comfort
7.3
Boarding
7.7
Food
6.7
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Crew
8.1
Overall
7.4
Comfort
7.3
Boarding
7.7
Food
6.7
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Crew
8.1
Overall
7.4
Comfort
7.3
Boarding
7.7
Food
6.7
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Madison to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Des Moines flight routes
Flights by cabin class
Other flight options
Other flights from Madison
Popular flights
Alternative routes for Madison to Des Moines
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 10, 2026.
Search flights from Madison to Des Moines by cabin class
Find flights from Madison to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Madison and Des Moines flights
Browse other Madison and Des Moines flight options. Last updated on October 10, 2026.
Other flights from Madison
Browse through other flights departing from Madison. Flights are based on user searches made on Cheapflights and were last updated on October 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Madison to Des Moines
Discover the top 2 airlines that operate flights from Madison to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$488 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$278 | Average$289 | FlexibilityNo cancel fee | On-time69% |