$292+ Cheap flights from Missoula to Des Moines (MSO - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel.
MSO — DSM
Oct 11 — Oct 181
Round-trip
1 adult, Economy
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Find cheap flights from Missoula to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missoula to Des Moines
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Cheapest flights from Missoula to Des MoinesExplore the most affordable flight options available from Missoula to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
Explore the most affordable flight options available from Missoula to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:19 pm -
1 stop5h 29m
Sun 10/45:45 am -
1 stop5h 12m
Deal found 9/9![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:27 am -
1 stop6h 44m
Sun 1/104:00 pm -
1 stop5h 12m
Deal found 9/7![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/118:27 am -
1 stop6h 44m
Fri 1/84:00 pm -
2 stops7h 56m
Deal found 9/7![Delta logo]()
$354
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:10 am -
2 stops10h 01m
Sat 1/94:00 pm -
2 stops7h 56m
Deal found 9/7![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:38 pm -
1 stop5h 23m
Mon 10/55:45 am -
1 stop5h 12m
Deal found 9/9![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:19 pm -
1 stop5h 29m
Sun 10/45:45 am -
1 stop5h 12m
Deal found 9/7![United Airlines logo]()
$439
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:28 pm -
2 stops24h 00m
Sun 1/1010:07 pm -
1 stop19h 50m
Deal found 9/7![Multiple Airlines logo]()
$451
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:50 am -
2 stops11h 06m
Sun 1/107:12 am -
1 stop6h 23m
Deal found 9/7![American Airlines logo]()
$459
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:50 am -
2 stops11h 06m
Sat 1/99:37 am -
2 stops11h 50m
Deal found 9/7![American Airlines logo]()
$464
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:10 am -
2 stops10h 01m
Sun 1/104:00 pm -
2 stops7h 56m
Deal found 9/7![Delta logo]()
$484
Best flights from Missoula to Des MoinesDiscover carefully curated flight deals from Missoula to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
Discover carefully curated flight deals from Missoula to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:38 pm -
2 stops7h 57m
Sun 10/45:45 am -
1 stop5h 12m
Deal found 9/9![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:10 am -
2 stops10h 01m
Fri 1/84:00 pm -
2 stops7h 56m
Deal found 9/7![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:27 pm -
1 stop4h 54m
Sat 1/95:03 pm -
1 stop5h 23m
Deal found 9/7![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/232:27 pm -
1 stop5h 05m
Tue 1/269:09 am -
1 stop5h 18m
Deal found 9/10![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:38 pm -
1 stop5h 23m
Mon 10/55:45 am -
1 stop5h 12m
Deal found 9/9![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/122:27 pm -
1 stop4h 54m
Fri 1/85:03 pm -
1 stop5h 23m
Deal found 9/7![United Airlines logo]()
$494
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:15 am -
1 stop5h 16m
Thu 11/55:12 pm -
1 stop5h 35m
Deal found 9/10![United Airlines logo]()
$548
Last-minute flights from Missoula to Des MoinesDiscover last-minute flight deals from Missoula to Des Moines. Data last updated September 11, 2026 and is based on user searches.
Discover last-minute flight deals from Missoula to Des Moines. Data last updated September 11, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:40 pm -
1 stop4h 46m
Sun 9/135:45 am -
1 stop5h 17m
Deal found 9/8![United Airlines logo]()
$509
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am -
1 stop7h 06m
Mon 9/215:59 pm -
1 stop6h 43m
Deal found 9/8![Delta logo]()
$489
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:17 pm -
1 stop5h 16m
Mon 9/215:45 am -
2 stops10h 39m
Deal found 9/8![United Airlines logo]()
$503
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:19 pm -
1 stop5h 29m
Sun 10/45:45 am -
1 stop5h 12m
Deal found 9/9![United Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:21 pm -
1 stop8h 06m
Thu 10/15:45 am -
1 stop5h 12m
Deal found 9/9![United Airlines logo]()
$585
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:38 pm -
1 stop5h 23m
Mon 10/55:45 am -
1 stop5h 12m
Deal found 9/9![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:19 pm -
1 stop5h 29m
Sun 10/45:45 am -
1 stop5h 12m
Deal found 9/7![United Airlines logo]()
$439
One-way flights from Missoula to Des MoinesSearch for one-way flight options from Missoula to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
Search for one-way flight options from Missoula to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:17 pm -
1 stop5h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/242:45 pm -
1 stop20h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Allegiant Air logo]()
$294
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:30 am -
1 stop4h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:00 am -
1 stop7h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Delta logo]()
$320
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:15 am -
2 stops10h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![United Airlines logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:49 pm -
2 stops20h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$410
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/242:45 pm -
2 stops28h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$412
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:00 am -
2 stops12h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$518
Find flight deals from Missoula to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Missoula (MSO) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $329 (United Airlines) |
One-way from | $292 (United Airlines) |
Popular in | December |
Cheapest in | April |
Average price | $776 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missoula to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
Use the filters below to find and compare flights from Missoula to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MissoulaDes Moines
MSO Missoula Johnson-Bell Field - DSM Des Moines
MSODSM
Missoula Johnson-Bell Field
Tue 11/24
2:45 pm-12:36 pm
1 stop20h 51m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$294
Quickest round-trip
MissoulaDes Moines
MSO Missoula Johnson-Bell Field - DSM Des Moines
MSODSM
Missoula Johnson-Bell Field
Mon 11/23
8:30 am-2:08 pm
1 stop4h 38m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$319
MissoulaDes Moines
MSO Missoula Johnson-Bell Field - DSM Des Moines
MSODSM
Missoula Johnson-Bell Field
Sun 9/20
6:00 am-2:06 pm
1 stop7h 06m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$320
MissoulaDes Moines
MSO Missoula Johnson-Bell Field - DSM Des Moines
MSODSM
Missoula Johnson-Bell Field
Wed 9/16
7:00 am-8:26 pm
2 stops12h 26m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$325
MissoulaDes Moines
MSO Missoula Johnson-Bell Field - DSM Des Moines
MSODSM
Missoula Johnson-Bell Field
Thu 10/1
2:38 pm-11:35 pm
2 stops7h 57m
Des Moines
Sun 10/4
5:45 am-9:57 am
1 stop5h 12m
$334
MissoulaDes Moines
MSO Missoula Johnson-Bell Field - DSM Des Moines
MSODSM
Missoula Johnson-Bell Field
Fri 12/11
2:27 pm-8:21 pm
1 stop4h 54m
Des Moines
Sat 1/9
5:03 pm-9:26 pm
1 stop5h 23m
$349
MissoulaDes Moines
MSO Missoula Johnson-Bell Field - DSM Des Moines
MSODSM
Missoula Johnson-Bell Field
Mon 11/23
6:15 am-5:28 pm
2 stops10h 13m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$355
MissoulaDes Moines
MSO Missoula Johnson-Bell Field - DSM Des Moines
MSODSM
Missoula Johnson-Bell Field
Fri 12/11
5:10 am-4:11 pm
2 stops10h 01m
Des Moines
Fri 1/8
4:00 pm-10:56 pm
2 stops7h 56m
$359
MissoulaDes Moines
MSO Missoula Johnson-Bell Field - DSM Des Moines
MSODSM
Missoula Johnson-Bell Field
Tue 11/24
2:45 pm-8:30 pm
2 stops28h 45m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$412
MissoulaDes Moines
MSO Missoula Johnson-Bell Field - DSM Des Moines
MSODSM
Missoula Johnson-Bell Field
Sat 1/23
2:27 pm-8:32 pm
1 stop5h 05m
Des Moines
Tue 1/26
9:09 am-1:27 pm
1 stop5h 18m
$419
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Missoula to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Missoula to Des Moines in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Missoula-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Missoula-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Missoula-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Missoula-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Missoula-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Missoula to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Missoula with our price prediction graph.
MSO-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 11, 2026.
See what other customers who have flown with United Airlines from Missoula to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.4
Crew
8.1
Comfort
7.3
Boarding
7.7
Entertainment
7.1
Food
6.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Overall
7.4
Crew
8.1
Comfort
7.3
Boarding
7.7
Entertainment
7.1
Food
6.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Missoula to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Other flights to Des Moines
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Missoula and Des Moines flights
Browse other Missoula and Des Moines flight options. Last updated on September 11, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Missoula to Des Moines
Discover the top airline that operate flights from Missoula to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$294 | Average$443 | FlexibilityNo cancel fee | On-time69% |