$974+ Cheap flights from Tyler to Des Moines (TYR - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
TYR — DSM
May 21 — May 281
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Tyler to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Tyler to Des Moines
Cheapest
Best
Last-minute
Cheapest flights from Tyler to Des MoinesExplore the most affordable flight options available from Tyler to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 21, 2026.
Explore the most affordable flight options available from Tyler to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 21, 2026.
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:55 pm
TYR
- DSM
1 stop6h 04m
American Airlines
Fri 5/87:05 pm
DSM
- TYR
1 stop15h 06m
American Airlines
Deal found 4/19![American Airlines logo]()
$974
Best flights from Tyler to Des MoinesDiscover carefully curated flight deals from Tyler to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 21, 2026.
Discover carefully curated flight deals from Tyler to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 21, 2026.
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:55 pm
TYR
- DSM
1 stop6h 04m
American Airlines
Fri 5/87:05 pm
DSM
- TYR
1 stop15h 06m
American Airlines
Deal found 4/19![American Airlines logo]()
$974
Last-minute flights from Tyler to Des MoinesDiscover last-minute flight deals from Tyler to Des Moines. Data last updated April 21, 2026 and is based on user searches.
Discover last-minute flight deals from Tyler to Des Moines. Data last updated April 21, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:55 pm
TYR
- DSM
1 stop6h 04m
American Airlines
Fri 5/87:05 pm
DSM
- TYR
1 stop15h 06m
American Airlines
Deal found 4/19![American Airlines logo]()
$974
Find flight deals from Tyler to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Tyler (TYR) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $974 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Tyler to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 21, 2026.
Use the filters below to find and compare flights from Tyler to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
TylerDes Moines
TYR - DSM
TYRDSM
Tyler Pounds Field
Mon 5/4
5:55 pm-11:59 pm
1 stop6h 04m
Des Moines
Fri 5/8
7:05 pm-10:11 am
1 stop15h 06m
$974
Sorted by cheapest first
Compare providers for flights from Tyler to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Tyler to Des Moines in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Tyler-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Tyler-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Tyler-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Tyler-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Tyler-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Tyler to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Tyler with our price prediction graph.
TYR-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Tyler to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Des Moines flight routes
Flights by cabin class
Other flight options
Other flights from Tyler
Popular flights