HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$297+ Cheap flights from Islip, NY to Des Moines (ISP - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/25. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — DSM
Jun 20 — Jun 271
Sat 6/20
Sat 6/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Islip to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Islip to Des Moines

Cheapest flights from Islip to Des Moines
Explore the most affordable flight options available from Islip to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2026.

This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/142:55 pm
ISP
-
DSM
2 stops8h 50m
Southwest
Fri 7/174:40 pm
DSM
-
ISP
2 stops16h 05m
Southwest
Deal found 5/21$481
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:00 am
ISP
-
DSM
2 stops13h 35m
Southwest
Wed 5/275:30 am
DSM
-
ISP
2 stops10h 05m
Southwest
Deal found 5/21$977

Find flight deals from Islip to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$481
(Southwest)

One-way from

$297
(Kiwi.com)

Popular in

January

Cheapest in

September

Average price

$478
Provider with most accurate pricing for New York (NYC)-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for New York (NYC)-Des Moines flights.
Search Deals
From Islip Long Island to Des Moines
Search Deals
One-way flight from Islip Long Island to Des Moines
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($44 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 21, 2026.
Use the filters below to find and compare flights from Islip to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

IslipDes Moines

ISP - DSM

ISPDSM

Islip Long Island

Tue 7/14

2:55 pm-10:45 pm

2 stops8h 50m

Des Moines

Fri 7/17

4:40 pm-9:45 am

2 stops16h 05m

$481
Cheapest one-way
Quickest one-way

IslipDes Moines

ISP - DSM

ISPDSM

Islip Long Island

Thu 6/25

6:46 pm-1:30 pm

2 stops43h 44m

$297

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/18

Sorted by cheapest first

Best time to book a flight from Islip to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Islip to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Islip, New York to Des Moines?

    Departing from Islip, New York to Des Moines will take you 8h 50m. Islip, New York and Des Moines are separated by a distance of 1067 mi.

  • Can I find deals for flights from Islip to Des Moines that include hotel bookings?

    Yes. In addition to deals on Islip to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Des Moines.

  • Can I find deals for business class flights from Islip to Des Moines?

    Yes. Cheapflights offers flight deals from Islip to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.