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Des Moines

$242+ Cheap flights from Syracuse to Des Moines (SYR - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/13. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — DSM
Jul 7 — Jul 141
Mon 7/7
Mon 7/14
1 adult, Economy
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Cheap flight deals from Syracuse to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 2, 2025.

Round-trip from

$259
(United Airlines)

One-way from

$242
(Delta)

Popular in

September

Cheapest in

January

Average price

$408
From Syracuse Hancock Intl to Des Moines
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One-way flight from Syracuse Hancock Intl to Des Moines
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Highest demand for flights based on searches. 20% potential increase in price ($99 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Syracuse to Des Moines

Cheapest flights from Syracuse to Des Moines
Explore the most affordable flight options available from Syracuse to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:20 amSYR - DSM
1 stop5h 19mUnited Airlines
Sat 9/133:25 pmDSM - SYR
1 stop4h 40mUnited Airlines
Deal found 7/1$259
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2312:45 pmSYR - DSM
2 stops8h 26mAmerican Airlines
Wed 10/296:07 pmDSM - SYR
1 stop4h 22mAmerican Airlines
Deal found 7/1$279
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/166:10 amSYR - DSM
1 stop4h 28mDelta
Sun 7/205:52 pmDSM - SYR
1 stop4h 15mDelta
Deal found 7/1$334
This Mytrip deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/235:55 pmSYR - DSM
2 stops24h 47mMultiple Airlines
Sun 7/276:30 amDSM - SYR
2 stops26h 14mMultiple Airlines
Deal found 7/1$414

Cheapflights Fare Finder

Customize your flight search to find flights from Syracuse to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
Use the filters below to find and compare flights from Syracuse to Des Moines that are best for you.

Fly from

Syracuse

Fly to

Des Moines

Route

Depart

Return

Price

SyracuseDes Moines

SYR - DSM

SYRDSM

Syracuse Hancock Intl

Thu 9/11

6:20 am-10:39 am

1 stop5h 19m

Des Moines

Sat 9/13

3:25 pm-9:05 pm

1 stop4h 40m

$259

SyracuseDes Moines

SYR - DSM

SYRDSM

Syracuse Hancock Intl

Thu 10/23

12:45 pm-8:11 pm

2 stops8h 26m

Des Moines

Wed 10/29

6:07 pm-11:29 pm

1 stop4h 22m

$279

SyracuseDes Moines

SYR - DSM

SYRDSM

Syracuse Hancock Intl

Wed 7/16

6:10 am-9:38 am

1 stop4h 28m

Des Moines

Sun 7/20

5:52 pm-11:07 pm

1 stop4h 15m

$334

SyracuseDes Moines

SYR - DSM

SYRDSM

Syracuse Hancock Intl

Wed 7/23

5:55 pm-5:42 pm

2 stops24h 47m

Des Moines

Sun 7/27

6:30 am-9:44 am

2 stops26h 14m

$414

SyracuseDes Moines

SYR - DSM

SYRDSM

Syracuse Hancock Intl

Sun 7/13

6:10 am-9:38 am

1 stop4h 28m

$242

SyracuseDes Moines

SYR - DSM

SYRDSM

Syracuse Hancock Intl

Tue 7/29

6:09 am-2:41 pm

2 stops9h 32m

$268

SyracuseDes Moines

SYR - DSM

SYRDSM

Syracuse Hancock Intl

Mon 7/28

8:20 pm-11:44 pm

1 stop4h 24m

$271

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Syracuse to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Des Moines

What is the cheapest month to book a flight from Syracuse to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Syracuse to Des Moines (average of $336). Flying from Syracuse to Des Moines in June is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to DSM?

Find hourly flight availability from Syracuse to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 2, 2025.

One of the essential ways to save on airfare from Syracuse to Des Moines is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 18% on airfare.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated July 2, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Syracuse to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,975 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,975 reviews
Delta
8.0
Very good
7,975 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,861 reviews
Delta
8.0
Very good
7,975 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,975 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Syracuse to Des Moines round-trip?

    Currently priced at $259, United Airlines will fly you from Syracuse to Des Moines and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and Delta - these airlines can fly you to your destination from $279 and $334, respectively. You may be able to fly from Syracuse to Des Moines for 34% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Syracuse to Des Moines one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $242. However, be on the lookout for offers from United Airlines and American Airlines, as they are both options that can get you from Syracuse to Des Moines for a low price.

  • Can I find deals for flights from Syracuse to Des Moines that include hotel bookings?

    Yes. In addition to deals on Syracuse to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Des Moines.

  • Can I find deals for business class flights from Syracuse to Des Moines?

    Yes. Cheapflights offers flight deals from Syracuse to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Syracuse to Des Moines (average of $336). Flying from Syracuse to Des Moines in June is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Syracuse?

Book flights to Syracuse if you plan to visit one of these locations
Altoona
Ames
Johnston
Boone
West Des Moines
Ankeny

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Alternative routes for Syracuse to Des Moines

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Top 3 airlines flying from Syracuse to Des Moines

Discover the top 3 airlines that operate flights from Syracuse to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$206Average$348FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$392FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$300Average$407FlexibilityNo cancel feeOn-time69%

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