Iowa

$185+ Cheap flights from Syracuse (SYR) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/12. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — DSM
Jun 12 — Jun 191
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Cheap flight deals from Syracuse to Iowa

Cheapest flights from Syracuse to Iowa
Explore the most affordable flight options available from Syracuse to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 13, 2026.

This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/98:23 pm
SYR
-
LSE
1 stop4h 56m
American Airlines
Sat 6/135:33 pm
LSE
-
SYR
1 stop5h 26m
American Airlines
Deal found 5/8$323
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
SYR
-
MLI
1 stop5h 20m
Delta
Wed 6/35:17 pm
MLI
-
SYR
1 stop5h 35m
Delta
Deal found 5/10$329
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:36 pm
SYR
-
OMA
1 stop7h 33m
American Airlines
Tue 10/136:23 pm
OMA
-
SYR
1 stop4h 54m
American Airlines
Deal found 5/12$330
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:30 am
SYR
-
DSM
1 stop6h 35m
American Airlines
Tue 7/76:33 pm
DSM
-
SYR
1 stop4h 28m
American Airlines
Deal found 5/11$335
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:30 pm
SYR
-
LSE
1 stop4h 51m
American Airlines
Tue 9/15:15 pm
LSE
-
SYR
1 stop4h 36m
American Airlines
Deal found 5/11$345
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:07 pm
SYR
-
OMA
1 stop6h 28m
Delta
Mon 7/275:40 pm
OMA
-
SYR
1 stop4h 33m
Delta
Deal found 5/12$349
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:15 am
SYR
-
DSM
1 stop9h 00m
United Airlines
Fri 6/121:35 pm
DSM
-
SYR
1 stop9h 09m
United Airlines
Deal found 5/8$349
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am
SYR
-
OMA
2 stops7h 16m
United Airlines
Thu 11/193:15 pm
OMA
-
SYR
1 stop4h 53m
United Airlines
Deal found 5/10$354
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:49 pm
SYR
-
DSM
1 stop4h 56m
United Airlines
Tue 6/21:35 pm
DSM
-
SYR
1 stop9h 09m
United Airlines
Deal found 5/12$357
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:15 am
SYR
-
OMA
1 stop5h 12m
United Airlines
Wed 7/2911:23 am
OMA
-
SYR
1 stop4h 25m
United Airlines
Deal found 5/9$359
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:00 am
SYR
-
MLI
1 stop5h 22m
Delta
Mon 8/36:00 am
MLI
-
SYR
1 stop8h 07m
Delta
Deal found 5/10$359
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:15 am
SYR
-
OMA
1 stop5h 12m
United Airlines
Tue 7/2812:57 pm
OMA
-
SYR
2 stops10h 02m
United Airlines
Deal found 5/9$365

Find flight deals from Syracuse to Iowa

Keep the following information in mind while searching for Syracuse to Iowa flight deals. Data was last updated May 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$323
(American Airlines)

One-way from

$185
(Kiwi.com)

Popular in

June

Cheapest in

September

Average price

$432
Provider with most accurate pricing for Syracuse Hancock Intl-Des Moines flight deals.
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Des Moines flights.
From Syracuse Hancock Intl to Iowa
One-way flight from Syracuse Hancock Intl to Iowa
Highest demand for flights based on searches. 17% potential increase in price ($100 potential increase over avg. RT price).
Cheapest flight prices on average. 7% potential price decrease ($32 potential savings vs. average RT price).
Average for round-trip flights in May 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Syracuse to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SyracuseLa Crosse

SYR - LSE

SYRLSE

Syracuse Hancock Intl

Tue 6/9

8:23 pm-12:19 am

1 stop4h 56m

La Crosse

Sat 6/13

5:33 pm-11:59 pm

1 stop5h 26m

$323

SyracuseMoline

SYR - MLI

SYRMLI

Syracuse Hancock Intl

Wed 5/27

6:00 am-10:20 am

1 stop5h 20m

Moline Quad-City

Wed 6/3

5:17 pm-11:52 pm

1 stop5h 35m

$329

SyracuseMoline

SYR - MLI

SYRMLI

Syracuse Hancock Intl

Wed 5/27

6:01 am-10:37 am

1 stop5h 36m

Moline Quad-City

Wed 6/3

4:24 pm-10:52 pm

1 stop5h 28m

$329
Quickest round-trip

SyracuseLa Crosse

SYR - LSE

SYRLSE

Syracuse Hancock Intl

Thu 8/27

8:30 pm-12:21 am

1 stop4h 51m

La Crosse

Tue 9/1

5:15 pm-10:51 pm

1 stop4h 36m

$345

SyracuseDes Moines

SYR - DSM

SYRDSM

Syracuse Hancock Intl

Sat 6/6

8:15 am-4:15 pm

1 stop9h 00m

Des Moines

Fri 6/12

1:35 pm-11:44 pm

1 stop9h 09m

$349

SyracuseOmaha

SYR - OMA

SYROMA

Syracuse Hancock Intl

Mon 7/20

6:07 pm-11:35 pm

1 stop6h 28m

Omaha Eppley Airfield

Mon 7/27

5:40 pm-11:13 pm

1 stop4h 33m

$349

SyracuseOmaha

SYR - OMA

SYROMA

Syracuse Hancock Intl

Mon 6/8

6:54 pm-11:50 pm

1 stop5h 56m

Omaha Eppley Airfield

Sun 6/14

5:03 pm-11:09 pm

1 stop5h 06m

$349

SyracuseDes Moines

SYR - DSM

SYRDSM

Syracuse Hancock Intl

Wed 5/27

5:49 pm-9:45 pm

1 stop4h 56m

Des Moines

Tue 6/2

1:35 pm-11:44 pm

1 stop9h 09m

$357

SyracuseMoline

SYR - MLI

SYRMLI

Syracuse Hancock Intl

Fri 7/31

6:00 am-10:22 am

1 stop5h 22m

Moline Quad-City

Wed 8/5

11:08 am-11:17 pm

2 stops11h 09m

$374

SyracuseOmaha

SYR - OMA

SYROMA

Syracuse Hancock Intl

Fri 8/21

6:00 am-2:15 pm

2 stops9h 15m

Omaha Eppley Airfield

Mon 8/24

3:11 pm-9:05 pm

1 stop4h 54m

$381

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/10

Showing 1-10 of 46 resultsSorted by cheapest first
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Best time to book a flight from Syracuse to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Iowa

What is the cheapest month to book a flight from Syracuse to Iowa?

Currently, October is the cheapest month in which you can book a flight from Syracuse to Iowa (average of $206). Flying from Syracuse to Iowa in November is currently the most expensive (average of $388). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Syracuse to Iowa?

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated May 13, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Syracuse to Iowa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.8

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work

Comfort

7.8

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work

Comfort

7.8

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work

Comfort

7.8

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Syracuse to Iowa?

    Located just 4.8 mi from the city center, Syracuse Hancock Intl (SYR) is the airport most travelers will use when flying to Iowa from Syracuse.

  • How long is the flight from Syracuse to Iowa?

    For as low as $323, American Airlines can have you in Iowa from Syracuse in 4h 56m. Airlines will cover a distance of 760 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Syracuse to Iowa?

  • Can I find deals for flights from Syracuse to Iowa that include hotel bookings?

    Yes. In addition to deals on Syracuse to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Iowa.

  • Can I find deals for business class flights from Syracuse to Iowa?

    Yes. Cheapflights offers flight deals from Syracuse to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Iowa?

    Currently, October is the cheapest month in which you can book a flight from Syracuse to Iowa (average of $206). Flying from Syracuse to Iowa in November is currently the most expensive (average of $388). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Syracuse to Iowa

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Syracuse to Iowa

Discover the top 3 airlines that operate flights from Syracuse to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$248Average$410FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$258Average$370FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$444FlexibilityNo cancel feeOn-timeN/A

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