$112+ Cheap flights from Cleveland to Des Moines (CLE - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — DSM
Oct 11 — Oct 181
Round-trip
1 adult, Economy
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Find cheap flights from Cleveland to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Cleveland to Des Moines
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Cheapest flights from Cleveland to Des MoinesExplore the most affordable flight options available from Cleveland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
Explore the most affordable flight options available from Cleveland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:59 pm -
1 stop11h 26m
Sun 10/256:37 pm -
2 stops16h 32m
Deal found 9/7![Multiple Airlines logo]()
$271
This CheapOair deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:24 pm -
1 stop7h 09m
Mon 10/128:25 pm -
1 stop18h 20m
Deal found 9/7![Frontier logo]()
$289
This Priceline deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:24 pm -
1 stop7h 09m
Sun 9/2711:29 am -
1 stop8h 10m
Deal found 9/8![Frontier logo]()
$290
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/102:02 pm -
1 stop4h 46m
Sat 10/1711:27 am -
1 stop4h 33m
Deal found 9/10![United Airlines logo]()
$309
This Priceline deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/111:24 pm -
1 stop7h 09m
Sun 9/1311:29 am -
1 stop8h 10m
Deal found 9/7![Frontier logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am -
2 stops14h 57m
Mon 9/2810:05 am -
1 stop12h 53m
Deal found 9/9![Multiple Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:24 pm -
1 stop7h 09m
Mon 10/58:30 pm -
2 stops32h 49m
Deal found 9/11![Frontier logo]()
$329
Best flights from Cleveland to Des MoinesDiscover carefully curated flight deals from Cleveland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
Discover carefully curated flight deals from Cleveland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:29 pm -
1 stop29h 39m
Mon 9/2810:05 am -
1 stop12h 53m
Deal found 9/9![Multiple Airlines logo]()
$332
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop5h 17m
Fri 10/96:54 pm -
1 stop5h 03m
Deal found 9/10![Delta logo]()
$355
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:50 pm -
2 stops7h 20m
Fri 10/94:30 pm -
1 stop3h 30m
Deal found 9/10![Southwest logo]()
$360
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:00 am -
1 stop6h 15m
Mon 9/286:55 pm -
1 stop4h 04m
Deal found 9/9![United Airlines logo]()
$477
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:25 pm -
1 stop4h 25m
Sat 10/171:20 pm -
2 stops7h 40m
Deal found 9/10![Southwest logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:00 am -
2 stops31h 08m
Mon 9/2810:05 am -
1 stop12h 53m
Deal found 9/7![Multiple Airlines logo]()
$430
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:50 pm -
2 stops7h 25m
Mon 10/124:30 pm -
1 stop3h 30m
Deal found 9/7![Southwest logo]()
$392
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:50 pm -
2 stops7h 20m
Mon 10/55:10 am -
2 stops6h 45m
Deal found 9/11![Southwest logo]()
$417
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:15 am -
2 stops5h 15m
Mon 9/283:50 pm -
2 stops5h 25m
Deal found 9/7![Southwest logo]()
$447
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:25 pm -
1 stop5h 35m
Sun 9/275:40 am -
1 stop3h 45m
Deal found 9/8![Southwest logo]()
$477
Last-minute flights from Cleveland to Des MoinesDiscover last-minute flight deals from Cleveland to Des Moines. Data last updated September 11, 2026 and is based on user searches.
Discover last-minute flight deals from Cleveland to Des Moines. Data last updated September 11, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/111:24 pm -
1 stop7h 09m
Sun 9/1311:29 am -
1 stop8h 10m
Deal found 9/7![Frontier logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Thu 9/246:00 am -
2 stops14h 57m
Mon 9/2810:05 am -
1 stop12h 53m
Deal found 9/9![Multiple Airlines logo]()
$321
This Priceline deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:24 pm -
1 stop7h 09m
Sun 9/2711:29 am -
1 stop8h 10m
Deal found 9/8![Frontier logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:24 pm -
1 stop7h 09m
Mon 10/58:30 pm -
2 stops32h 49m
Deal found 9/11![Frontier logo]()
$329
This CheapOair deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:24 pm -
1 stop7h 09m
Mon 10/128:25 pm -
1 stop18h 20m
Deal found 9/7![Frontier logo]()
$289
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/102:02 pm -
1 stop4h 46m
Sat 10/1711:27 am -
1 stop4h 33m
Deal found 9/10![United Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:59 pm -
1 stop11h 26m
Sun 10/256:37 pm -
2 stops16h 32m
Deal found 9/7![Multiple Airlines logo]()
$271
One-way flights from Cleveland to Des MoinesSearch for one-way flight options from Cleveland to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
Search for one-way flight options from Cleveland to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:45 pm -
2 stops23h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/173:46 pm -
2 stops23h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$116
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:10 am -
1 stop3h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Southwest logo]()
$182
This Frontier deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/211:24 pm -
1 stop7h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Frontier logo]()
$206
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/274:23 pm -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![United Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:00 am -
2 stops14h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$255
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:54 am -
1 stop4h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$261
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:00 am -
2 stops12h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Southwest logo]()
$337
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/299:35 pm -
1 stop4h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Southwest logo]()
$355
Find flight deals from Cleveland to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $271 (Kiwi.com) |
One-way from | $112 (Kiwi.com) |
Popular in | June |
Cheapest in | November |
Average price | $628 |
Cheapflights Fare Finder
Customize your flight search to find flights from Cleveland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
Use the filters below to find and compare flights from Cleveland to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ClevelandDes Moines
CLE Cleveland Hopkins Intl - DSM Des Moines
CLEDSM
Cleveland Hopkins Intl
Wed 10/7
3:45 pm-2:42 pm
2 stops23h 57m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$112
ClevelandDes Moines
CLE Cleveland Hopkins Intl - DSM Des Moines
CLEDSM
Cleveland Hopkins Intl
Sat 10/17
3:46 pm-2:42 pm
2 stops23h 56m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$116
ClevelandDes Moines
CLE Cleveland Hopkins Intl - DSM Des Moines
CLEDSM
Cleveland Hopkins Intl
Sat 10/17
9:21 pm-12:14 am
1 stop3h 53m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$182
Quickest round-trip
ClevelandDes Moines
CLE Cleveland Hopkins Intl - DSM Des Moines
CLEDSM
Cleveland Hopkins Intl
Sat 10/17
9:10 am-12:00 pm
1 stop3h 50m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$182
ClevelandDes Moines
CLE Cleveland Hopkins Intl - DSM Des Moines
CLEDSM
Cleveland Hopkins Intl
Wed 10/7
10:23 am-1:30 pm
1 stop4h 07m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$182
ClevelandDes Moines
CLE Cleveland Hopkins Intl - DSM Des Moines
CLEDSM
Cleveland Hopkins Intl
Sun 9/27
4:23 pm-9:23 pm
1 stop6h 00m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$239
ClevelandDes Moines
CLE Cleveland Hopkins Intl - DSM Des Moines
CLEDSM
Cleveland Hopkins Intl
Sun 9/27
6:00 am-7:57 pm
2 stops14h 57m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$255
ClevelandDes Moines
CLE Cleveland Hopkins Intl - DSM Des Moines
CLEDSM
Cleveland Hopkins Intl
Wed 9/16
10:54 am-2:06 pm
1 stop4h 12m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$261
ClevelandDes Moines
CLE Cleveland Hopkins Intl - DSM Des Moines
CLEDSM
Cleveland Hopkins Intl
Thu 9/24
5:29 pm-10:08 pm
1 stop29h 39m
Des Moines
Mon 9/28
10:05 am-11:58 pm
1 stop12h 53m
$332
ClevelandDes Moines
CLE Cleveland Hopkins Intl - DSM Des Moines
CLEDSM
Cleveland Hopkins Intl
Mon 9/21
11:00 am-10:15 pm
2 stops12h 15m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$337
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Cleveland to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Cleveland to Des Moines in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Cleveland-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Cleveland-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Cleveland-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Cleveland-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cleveland-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Cleveland to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Cleveland with our price prediction graph.
CLE-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Cleveland to Des Moines
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 11, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Cleveland to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Entertainment
7.5
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Entertainment
7.5
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Entertainment
7.5
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Entertainment
7.5
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Cleveland to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 11, 2026.
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Cleveland and Des Moines flights
Browse other Cleveland and Des Moines flight options. Last updated on September 11, 2026.
Other flights from Cleveland
Browse through other flights departing from Cleveland. Flights are based on user searches made on Cheapflights and were last updated on September 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Cleveland to Des Moines
Discover the top 4 airlines that operate flights from Cleveland to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$284 | Average$381 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$295 | Average$410 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$296 | Average$372 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$319 | Average$406 | FlexibilityNo cancel fee | On-time63% |