$126+ Cheap flights from Des Moines to Cleveland (DSM - CLE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CLE
May 25 — Jun 11
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Cleveland with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Cleveland
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Cheapest flights from Des Moines to ClevelandExplore the most affordable flight options available from Des Moines to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2026.
Explore the most affordable flight options available from Des Moines to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2026.
This Trip.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:16 pm
DSM
- CLE
1 stop20h 36m
Frontier
Sun 5/1012:47 pm
CLE
- DSM
1 stop25h 44m
Frontier
Deal found 4/22![Frontier logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:00 am
DSM
- CLE
1 stop16h 07m
Multiple Airlines
Wed 5/137:24 pm
CLE
- DSM
2 stops20h 51m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/107:45 am
DSM
- CLE
2 stops27h 05m
Multiple Airlines
Tue 5/198:07 pm
CLE
- DSM
1 stop17h 52m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:16 pm
DSM
- CLE
1 stop20h 26m
Multiple Airlines
Tue 5/198:07 pm
CLE
- DSM
1 stop17h 52m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$251
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:56 pm
DSM
- CLE
1 stop3h 24m
Delta
Wed 5/206:00 am
CLE
- DSM
1 stop5h 16m
Delta
Deal found 4/20![Delta logo]()
$257
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:15 am
DSM
- CLE
1 stop6h 08m
Delta
Tue 5/196:00 am
CLE
- DSM
1 stop5h 16m
Delta
Deal found 4/20![Delta logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:30 am
DSM
- CLE
1 stop10h 11m
Multiple Airlines
Tue 5/198:07 pm
CLE
- DSM
1 stop17h 52m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$264
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:30 am
DSM
- CLE
2 stops10h 30m
Southwest
Tue 6/95:35 am
CLE
- DSM
1 stop10h 30m
Southwest
Deal found 4/23![Southwest logo]()
$269
Best flights from Des Moines to ClevelandDiscover carefully curated flight deals from Des Moines to Cleveland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 25, 2026.
Discover carefully curated flight deals from Des Moines to Cleveland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 25, 2026.
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:30 am
DSM
- CLE
2 stops10h 30m
Southwest
Tue 6/95:35 am
CLE
- DSM
1 stop10h 30m
Southwest
Deal found 4/23![Southwest logo]()
$269
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:56 am
DSM
- CLE
1 stop6h 35m
Delta
Sun 6/76:00 am
CLE
- DSM
1 stop5h 14m
Delta
Deal found 4/20![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:00 am
DSM
- CLE
1 stop5h 41m
United Airlines
Sat 6/136:00 pm
CLE
- DSM
1 stop4h 40m
United Airlines
Deal found 4/24![United Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:25 am
DSM
- CLE
2 stops11h 10m
Southwest
Tue 6/168:25 am
CLE
- DSM
1 stop4h 05m
Southwest
Deal found 4/24![Southwest logo]()
$340
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:28 pm
DSM
- CLE
1 stop4h 42m
Delta
Mon 5/182:13 pm
CLE
- DSM
1 stop3h 35m
Delta
Deal found 4/20![Delta logo]()
$371
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:00 am
DSM
- CLE
1 stop3h 54m
United Airlines
Fri 6/56:00 pm
CLE
- DSM
1 stop4h 40m
United Airlines
Deal found 4/23![United Airlines logo]()
$408
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:10 am
DSM
- CLE
1 stop4h 00m
Southwest
Sun 7/198:20 am
CLE
- DSM
1 stop4h 05m
Southwest
Deal found 4/23![Southwest logo]()
$387
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/161:30 pm
DSM
- CLE
2 stops8h 55m
Southwest
Mon 7/2012:05 pm
CLE
- DSM
2 stops11h 15m
Southwest
Deal found 4/20![Southwest logo]()
$417
Last-minute flights from Des Moines to ClevelandDiscover last-minute flight deals from Des Moines to Cleveland. Data last updated April 25, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Cleveland. Data last updated April 25, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:16 pm
DSM
- CLE
1 stop20h 36m
Frontier
Sun 5/1012:47 pm
CLE
- DSM
1 stop25h 44m
Frontier
Deal found 4/22![Frontier logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/107:45 am
DSM
- CLE
2 stops27h 05m
Multiple Airlines
Tue 5/198:07 pm
CLE
- DSM
1 stop17h 52m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:00 am
DSM
- CLE
1 stop16h 07m
Multiple Airlines
Wed 5/137:24 pm
CLE
- DSM
2 stops20h 51m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:16 pm
DSM
- CLE
1 stop20h 26m
Multiple Airlines
Tue 5/198:07 pm
CLE
- DSM
1 stop17h 52m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:16 pm
DSM
- CLE
1 stop20h 26m
Multiple Airlines
Wed 5/203:49 pm
CLE
- DSM
2 stops31h 42m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$273
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:56 pm
DSM
- CLE
1 stop3h 24m
Delta
Wed 5/206:00 am
CLE
- DSM
1 stop5h 16m
Delta
Deal found 4/20![Delta logo]()
$257
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:15 am
DSM
- CLE
1 stop6h 08m
Delta
Tue 5/196:00 am
CLE
- DSM
1 stop5h 16m
Delta
Deal found 4/20![Delta logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:30 am
DSM
- CLE
1 stop10h 11m
Multiple Airlines
Tue 5/198:07 pm
CLE
- DSM
1 stop17h 52m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$264
One-way flights from Des Moines to ClevelandSearch for one-way flight options from Des Moines to Cleveland. Find affordable one-way fares based on user searches. Data last updated April 25, 2026.
Search for one-way flight options from Des Moines to Cleveland. Find affordable one-way fares based on user searches. Data last updated April 25, 2026.
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:50 pm
DSM
- CLE
1 stop4h 08m
United Airlines
Deal found 4/20![United Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:45 am
DSM
- CLE
2 stops36h 12m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/34:40 pm
DSM
- CLE
1 stop28h 17m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$146
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/261:48 pm
DSM
- CLE
2 stops7h 28m
American Airlines
Deal found 4/20![American Airlines logo]()
$149
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2511:23 am
DSM
- CLE
1 stop5h 46m
United Airlines
Deal found 4/20![United Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/253:57 pm
DSM
- CLE
2 stops26h 22m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$154
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:37 pm
DSM
- CLE
1 stop7h 39m
American Airlines
Deal found 4/21![American Airlines logo]()
$176
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:10 am
DSM
- CLE
2 stops9h 10m
Southwest
Deal found 4/21![Southwest logo]()
$200
Find flight deals from Des Moines to Cleveland
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Cleveland (CLE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $220 (Trip.com) |
One-way from | $126 (Delta) |
Popular in | April |
Cheapest in | February |
Average price | $866 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2026.
Use the filters below to find and compare flights from Des Moines to Cleveland that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesCleveland
DSM - CLE
DSMCLE
Des Moines
Tue 6/2
5:30 am-5:00 pm
2 stops10h 30m
Cleveland Hopkins Intl
Tue 6/9
5:35 am-3:05 pm
1 stop10h 30m
$269
Des MoinesCleveland
DSM - CLE
DSMCLE
Des Moines
Wed 6/3
10:56 am-6:31 pm
1 stop6h 35m
Cleveland Hopkins Intl
Sun 6/7
6:00 am-10:14 am
1 stop5h 14m
$319
Des MoinesCleveland
DSM - CLE
DSMCLE
Des Moines
Tue 6/9
6:25 am-6:35 pm
2 stops11h 10m
Cleveland Hopkins Intl
Tue 6/16
8:25 am-11:30 am
1 stop4h 05m
$340
Des MoinesCleveland
DSM - CLE
DSMCLE
Des Moines
Wed 6/10
5:00 am-11:41 am
1 stop5h 41m
Cleveland Hopkins Intl
Sat 6/13
6:00 pm-9:40 pm
1 stop4h 40m
$367
Des MoinesCleveland
DSM - CLE
DSMCLE
Des Moines
Wed 5/13
5:28 pm-11:10 pm
1 stop4h 42m
Cleveland Hopkins Intl
Mon 5/18
2:13 pm-4:48 pm
1 stop3h 35m
$371
Quickest round-trip
Des MoinesCleveland
DSM - CLE
DSMCLE
Des Moines
Fri 7/17
5:10 am-10:10 am
1 stop4h 00m
Cleveland Hopkins Intl
Sun 7/19
8:20 am-11:25 am
1 stop4h 05m
$387
Des MoinesCleveland
DSM - CLE
DSMCLE
Des Moines
Mon 6/1
5:00 am-9:54 am
1 stop3h 54m
Cleveland Hopkins Intl
Fri 6/5
6:00 pm-9:40 pm
1 stop4h 40m
$408
Des MoinesCleveland
DSM - CLE
DSMCLE
Des Moines
Thu 7/16
1:30 pm-11:25 pm
2 stops8h 55m
Cleveland Hopkins Intl
Mon 7/20
12:05 pm-10:20 pm
2 stops11h 15m
$417
Cheapest one-way
Quickest one-way
Des MoinesCleveland
DSM - CLE
DSMCLE
Des Moines
Tue 5/26
6:50 pm-11:58 pm
1 stop4h 08m
$126
Des MoinesCleveland
DSM - CLE
DSMCLE
Des Moines
Tue 5/26
5:28 pm-11:10 pm
1 stop4h 42m
$126
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Cleveland
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Cleveland in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Cleveland flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Cleveland flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Cleveland flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Cleveland flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Cleveland flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Cleveland
Have a flexible travel schedule? Discover the best time to fly to Cleveland from Des Moines with our price prediction graph.
DSM-CLE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Cleveland
Reviews of airlines servicing Cleveland
Get insights into the airlines that provide service to Cleveland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cleveland. Reviews last updated April 25, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to Cleveland have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Cleveland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Cleveland?
Book flights to Cleveland if you plan to visit one of these locationsSandusky
Mentor
Avon
Mansfield
Beachwood
Wooster
Independence
Strongsville
Lakewood
Streetsboro
Medina
North Olmsted
Cuyahoga Falls
Cleveland Heights
Macedonia
Kent
Elyria
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Other flights to Cleveland
Explore flights to Cleveland departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 25, 2026.
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Des Moines and Cleveland flights
Browse other Des Moines and Cleveland flight options. Last updated on April 25, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on April 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Des Moines to Cleveland
Discover the top 4 airlines that operate flights from Des Moines to Cleveland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$108 | Average$386 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$256 | Average$386 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$256 | Average$331 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$416 | FlexibilityNo cancel fee | On-time69% |