$90+ Cheap flights from Des Moines (DSM) to Ohio
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CVG
May 24 — May 311
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to OhioExplore the most affordable flight options available from Des Moines to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
Explore the most affordable flight options available from Des Moines to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
This Priceline deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:16 pm
DSM
- DTW
1 stop8h 43m
Frontier
Mon 5/187:55 am
DTW
- DSM
1 stop6h 36m
Frontier
Deal found 4/22![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:16 pm
DSM
- DTW
1 stop8h 43m
Frontier
Fri 5/297:55 am
DTW
- DSM
1 stop6h 36m
Frontier
Deal found 4/20![Frontier logo]()
$180
This Trip.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:16 pm
DSM
- CLE
1 stop20h 36m
Frontier
Sun 5/1012:47 pm
CLE
- DSM
1 stop25h 44m
Frontier
Deal found 4/22![Frontier logo]()
$220
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:15 am
DSM
- CMH
1 stop6h 10m
Delta
Wed 6/107:01 am
CMH
- DSM
1 stop4h 42m
Delta
Deal found 4/23![Delta logo]()
$221
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/252:40 pm
DSM
- CMH
2 stops5h 20m
Southwest
Tue 9/16:35 am
CMH
- DSM
1 stop8h 20m
Southwest
Deal found 4/20![Southwest logo]()
$228
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/52:16 pm
DSM
- DTW
1 stop8h 43m
Frontier
Fri 6/127:45 am
DTW
- DSM
1 stop6h 46m
Frontier
Deal found 4/20![Frontier logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:00 am
DSM
- CLE
1 stop16h 07m
Multiple Airlines
Wed 5/137:24 pm
CLE
- DSM
2 stops20h 51m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$228
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:30 am
DSM
- CMH
1 stop3h 45m
Southwest
Wed 6/105:40 am
CMH
- DSM
2 stops6h 50m
Southwest
Deal found 4/21![Southwest logo]()
$236
This Trip.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:16 pm
DSM
- DTW
1 stop8h 43m
Frontier
Sun 5/101:20 pm
DTW
- DSM
1 stop25h 11m
Frontier
Deal found 4/19![Frontier logo]()
$241
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/261:37 pm
DSM
- CMH
1 stop6h 17m
American Airlines
Thu 5/288:23 am
CMH
- DSM
1 stop5h 55m
American Airlines
Deal found 4/20![American Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/107:45 am
DSM
- CLE
2 stops27h 05m
Multiple Airlines
Tue 5/198:07 pm
CLE
- DSM
1 stop17h 52m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:16 pm
DSM
- CLE
1 stop20h 26m
Multiple Airlines
Tue 5/198:07 pm
CLE
- DSM
1 stop17h 52m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$251
Best flights from Des Moines to OhioDiscover carefully curated flight deals from Des Moines to Ohio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
Discover carefully curated flight deals from Des Moines to Ohio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:45 am
DSM
- CMH
1 stop6h 15m
Delta
Tue 9/11:35 pm
CMH
- DSM
1 stop4h 34m
Delta
Deal found 4/20![Delta logo]()
$221
This Frontier deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:16 pm
DSM
- DTW
1 stop8h 43m
Frontier
Fri 5/297:55 am
DTW
- DSM
1 stop6h 36m
Frontier
Deal found 4/23![Frontier logo]()
$225
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:30 am
DSM
- CLE
2 stops10h 30m
Southwest
Tue 6/95:35 am
CLE
- DSM
1 stop10h 30m
Southwest
Deal found 4/23![Southwest logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/74:01 pm
DSM
- CAK
1 stop6h 56m
Multiple Airlines
Sun 6/147:55 pm
CAK
- DSM
1 stop22h 59m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$272
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:40 pm
DSM
- CMH
1 stop8h 11m
United Airlines
Wed 8/197:00 am
CMH
- DSM
1 stop4h 11m
United Airlines
Deal found 4/23![United Airlines logo]()
$296
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/61:37 pm
DSM
- CAK
1 stop5h 39m
American Airlines
Sat 6/136:47 pm
CAK
- DSM
1 stop6h 23m
American Airlines
Deal found 4/22![American Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:45 am
DSM
- CVG
1 stop12h 24m
Allegiant Air
Wed 5/204:48 pm
CVG
- DSM
1 stop17h 05m
Allegiant Air
Deal found 4/24![Allegiant Air logo]()
$391
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2311:57 am
DSM
- CMH
1 stop6h 46m
Delta
Tue 5/2610:47 am
CMH
- DSM
1 stop7h 19m
Delta
Deal found 4/23![Delta logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:07 pm
DSM
- CVG
2 stops18h 07m
Multiple Airlines
Mon 6/156:04 pm
CVG
- DSM
1 stop21h 00m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
DSM
- PIT
1 stop6h 09m
United Airlines
Wed 5/274:04 pm
PIT
- DSM
1 stop6h 41m
United Airlines
Deal found 4/20![United Airlines logo]()
$331
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:10 am
DSM
- CMH
2 stops10h 45m
Southwest
Wed 6/105:40 am
CMH
- DSM
2 stops6h 50m
Southwest
Deal found 4/23![Southwest logo]()
$335
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:56 am
DSM
- DAY
2 stops9h 16m
American Airlines
Sat 5/912:53 pm
DAY
- DSM
1 stop6h 42m
American Airlines
Deal found 4/20![American Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:41 pm
DSM
- CMH
1 stop4h 49m
Delta
Thu 6/112:00 pm
CMH
- DSM
1 stop3h 54m
Delta
Deal found 4/21![Delta logo]()
$326
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/82:16 pm
DSM
- CLE
1 stop19h 47m
Multiple Airlines
Mon 6/157:45 am
CLE
- DSM
1 stop11h 09m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$332
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:00 am
DSM
- PIT
1 stop7h 09m
United Airlines
Mon 5/254:04 pm
PIT
- DSM
1 stop4h 21m
United Airlines
Deal found 4/21![United Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
DSM
- CAK
2 stops10h 23m
American Airlines
Sat 5/98:23 am
CAK
- DSM
2 stops11h 12m
American Airlines
Deal found 4/20![American Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:30 am
DSM
- DTW
2 stops6h 30m
Southwest
Tue 6/168:55 am
DTW
- DSM
1 stop3h 35m
Southwest
Deal found 4/23![Southwest logo]()
$351
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:26 am
DSM
- CLE
1 stop3h 39m
Delta
Sun 6/76:00 am
CLE
- DSM
1 stop5h 14m
Delta
Deal found 4/23![Delta logo]()
$327
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:00 am
DSM
- CMH
2 stops8h 12m
United Airlines
Mon 5/255:54 pm
CMH
- DSM
1 stop4h 51m
United Airlines
Deal found 4/21![United Airlines logo]()
$356
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:30 am
DSM
- CLE
2 stops7h 30m
Southwest
Fri 5/155:10 pm
CLE
- DSM
2 stops6h 55m
Southwest
Deal found 4/22![Southwest logo]()
$356
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:56 pm
DSM
- PIT
1 stop3h 26m
Delta
Tue 5/195:59 pm
PIT
- DSM
1 stop3h 37m
Delta
Deal found 4/19![Delta logo]()
$337
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:30 pm
DSM
- CVG
1 stop7h 23m
American Airlines
Mon 5/258:59 pm
CVG
- DSM
1 stop4h 09m
American Airlines
Deal found 4/19![American Airlines logo]()
$387
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:01 pm
DSM
- CVG
1 stop7h 43m
United Airlines
Sat 5/306:50 am
CVG
- DSM
1 stop4h 37m
United Airlines
Deal found 4/23![United Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:40 am
DSM
- DTW
2 stops6h 00m
Southwest
Mon 8/247:30 pm
DTW
- DSM
1 stop3h 40m
Southwest
Deal found 4/21![Southwest logo]()
$360
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:51 am
DSM
- DAY
1 stop5h 08m
Delta
Sat 5/96:00 am
DAY
- DSM
1 stop6h 08m
Delta
Deal found 4/20![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:50 pm
DSM
- PIT
1 stop4h 09m
United Airlines
Wed 6/36:11 pm
PIT
- DSM
1 stop6h 05m
United Airlines
Deal found 4/23![United Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:41 pm
DSM
- CVG
1 stop4h 53m
Delta
Thu 6/116:23 am
CVG
- DSM
1 stop4h 20m
Delta
Deal found 4/20![Delta logo]()
$345
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:40 am
DSM
- PIT
2 stops6h 20m
Southwest
Sun 8/304:15 pm
PIT
- DSM
2 stops7h 20m
Southwest
Deal found 4/23![Southwest logo]()
$381
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:00 am
DSM
- DAY
1 stop6h 39m
United Airlines
Mon 5/115:43 am
DAY
- DSM
1 stop4h 40m
United Airlines
Deal found 4/21![United Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:37 pm
DSM
- DAY
1 stop7h 29m
American Airlines
Mon 5/254:16 pm
DAY
- DSM
1 stop4h 16m
American Airlines
Deal found 4/22![American Airlines logo]()
$461
Last-minute flights from Des Moines to OhioDiscover last-minute flight deals from Des Moines to Ohio. Data last updated April 24, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Ohio. Data last updated April 24, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:16 pm
DSM
- CLE
1 stop20h 36m
Frontier
Sun 5/1012:47 pm
CLE
- DSM
1 stop25h 44m
Frontier
Deal found 4/22![Frontier logo]()
$220
This Trip.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:16 pm
DSM
- DTW
1 stop8h 43m
Frontier
Sun 5/101:20 pm
DTW
- DSM
1 stop25h 11m
Frontier
Deal found 4/19![Frontier logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/107:45 am
DSM
- CLE
2 stops27h 05m
Multiple Airlines
Tue 5/198:07 pm
CLE
- DSM
1 stop17h 52m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:00 am
DSM
- CLE
1 stop16h 07m
Multiple Airlines
Wed 5/137:24 pm
CLE
- DSM
2 stops20h 51m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:16 pm
DSM
- CLE
1 stop20h 26m
Multiple Airlines
Tue 5/198:07 pm
CLE
- DSM
1 stop17h 52m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$251
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:56 pm
DSM
- CLE
1 stop3h 24m
Delta
Wed 5/206:00 am
CLE
- DSM
1 stop5h 16m
Delta
Deal found 4/20![Delta logo]()
$257
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:15 am
DSM
- CLE
1 stop6h 08m
Delta
Tue 5/196:00 am
CLE
- DSM
1 stop5h 16m
Delta
Deal found 4/20![Delta logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:30 am
DSM
- CLE
1 stop10h 11m
Multiple Airlines
Tue 5/198:07 pm
CLE
- DSM
1 stop17h 52m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$264
This Priceline deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:16 pm
DSM
- DTW
1 stop8h 43m
Frontier
Mon 5/187:55 am
DTW
- DSM
1 stop6h 36m
Frontier
Deal found 4/22![Frontier logo]()
$160
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
DSM
- CMH
1 stop4h 10m
American Airlines
Wed 5/208:32 am
CMH
- DSM
1 stop5h 39m
American Airlines
Deal found 4/22![American Airlines logo]()
$263
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/261:37 pm
DSM
- CMH
1 stop6h 17m
American Airlines
Thu 5/288:23 am
CMH
- DSM
1 stop5h 55m
American Airlines
Deal found 4/20![American Airlines logo]()
$243
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:16 pm
DSM
- DTW
1 stop8h 43m
Frontier
Fri 5/297:55 am
DTW
- DSM
1 stop6h 36m
Frontier
Deal found 4/20![Frontier logo]()
$180
One-way flights from Des Moines to OhioSearch for one-way flight options from Des Moines to Ohio. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
Search for one-way flight options from Des Moines to Ohio. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:16 pm
DSM
- DTW
1 stop8h 43m
Frontier
Deal found 4/20![Frontier logo]()
$90
This Frontier deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/242:16 pm
DSM
- DTW
1 stop8h 43m
Frontier
Deal found 4/22![Frontier logo]()
$95
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
DSM
- CMH
1 stop6h 12m
United Airlines
Deal found 4/20![United Airlines logo]()
$111
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/222:16 pm
DSM
- DTW
1 stop8h 43m
Frontier
Deal found 4/20![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:02 pm
DSM
- DTW
1 stop23h 14m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$119
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:50 pm
DSM
- CLE
1 stop4h 08m
United Airlines
Deal found 4/20![United Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:53 pm
DSM
- CVG
1 stop15h 17m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:08 pm
DSM
- CAK
1 stop5h 49m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$128
This Trip.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:00 am
DSM
- CVG
1 stop14h 55m
Allegiant Air
Deal found 4/19![Allegiant Air logo]()
$130
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:30 am
DSM
- CMH
2 stops11h 50m
Southwest
Deal found 4/23![Southwest logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:45 am
DSM
- CLE
2 stops36h 12m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$131
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:00 am
DSM
- CMH
1 stop3h 57m
United Airlines
Deal found 4/23![United Airlines logo]()
$133
Find flight deals from Des Moines to Ohio
Keep the following information in mind while searching for Des Moines to Ohio flight deals. Data was last updated April 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $160 (Priceline) |
One-way from | $90 (Frontier) |
Popular in | August |
Cheapest in | February |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Des Moines to Ohio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesColumbus
DSM - CMH
DSMCMH
Des Moines
Tue 8/25
5:45 am-1:00 pm
1 stop6h 15m
Columbus
Tue 9/1
1:35 pm-5:09 pm
1 stop4h 34m
$221
Des MoinesDetroit
DSM - DTW
DSMDTW
Des Moines
Wed 5/27
2:16 pm-11:59 pm
1 stop8h 43m
Detroit Metropolitan Wayne County
Fri 5/29
7:55 am-1:31 pm
1 stop6h 36m
$225
Des MoinesColumbus
DSM - CMH
DSMCMH
Des Moines
Sat 5/23
11:57 am-7:43 pm
1 stop6h 46m
Columbus
Tue 5/26
10:47 am-5:06 pm
1 stop7h 19m
$243
Des MoinesCleveland
DSM - CLE
DSMCLE
Des Moines
Tue 6/2
5:30 am-5:00 pm
2 stops10h 30m
Cleveland Hopkins Intl
Tue 6/9
5:35 am-3:05 pm
1 stop10h 30m
$269
Des MoinesAkron
DSM - CAK
DSMCAK
Des Moines
Sun 6/7
4:01 pm-11:57 pm
1 stop6h 56m
Akron/Canton
Sun 6/14
7:55 pm-5:54 pm
1 stop22h 59m
$272
Des MoinesColumbus
DSM - CMH
DSMCMH
Des Moines
Tue 8/18
1:40 pm-10:51 pm
1 stop8h 11m
Columbus
Wed 8/19
7:00 am-10:11 am
1 stop4h 11m
$296
Des MoinesCincinnati
DSM - CVG
DSMCVG
Des Moines
Mon 6/8
4:07 pm-11:14 am
2 stops18h 07m
Cincinnati Cinci./N. Kentucky
Mon 6/15
6:04 pm-2:04 pm
1 stop21h 00m
$309
Des MoinesColumbus
DSM - CMH
DSMCMH
Des Moines
Thu 6/4
6:41 pm-12:30 am
1 stop4h 49m
Columbus
Thu 6/11
2:00 pm-4:54 pm
1 stop3h 54m
$326
Des MoinesCleveland
DSM - CLE
DSMCLE
Des Moines
Wed 6/3
10:26 am-3:05 pm
1 stop3h 39m
Cleveland Hopkins Intl
Sun 6/7
6:00 am-10:14 am
1 stop5h 14m
$327
Des MoinesAkron
DSM - CAK
DSMCAK
Des Moines
Sat 6/6
1:37 pm-8:16 pm
1 stop5h 39m
Akron/Canton
Sat 6/13
6:47 pm-12:10 am
1 stop6h 23m
$329
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Ohio
Have a flexible travel schedule? Discover the best time to fly to Ohio from Des Moines with our price prediction graph.
DSM-DTW
DSM-CLE
DSM-CMH
DSM-CVG
DSM-PIT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Ohio
DSM-USOH
DSM-DTW
DSM-CLE
DSM-CMH
DSM-CVG
What is the cheapest month to book a flight from Des Moines to Ohio?
Currently, July is the cheapest month in which you can book a flight from Des Moines to Ohio (average of $108). Flying from Des Moines to Ohio in January is currently the most expensive (average of $309). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Ohio?
Reviews of airlines servicing Ohio
Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated April 24, 2026.
Read through reviews of airlines operating flights from Des Moines to Ohio, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Ohio
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Complete your trip
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Des Moines and Ohio flights
Browse other Des Moines and Ohio flight options. Last updated on April 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Des Moines to Ohio flights
Consider these flights traveling from Des Moines to Ohio.
Top 4 airlines flying from Des Moines to Ohio
Discover the top 4 airlines that operate flights from Des Moines to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$108 | Average$395 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$197 | Average$391 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$250 | Average$351 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$256 | Average$376 | FlexibilityNo cancel fee | On-time63% |