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Des Moines

$100+ Cheap flights from Ohio to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — DSM
Aug 23 — Aug 301
Sun 8/23
Sun 8/30
1 adult, Economy
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Cheap flight deals from Ohio to Des Moines

Cheapest flights from Ohio to Des Moines
Explore the most affordable flight options available from Ohio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.

This Frontier deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:30 pm
CVG
-
DSM
1 stop17h 26m
Frontier
Fri 9/182:51 pm
DSM
-
CVG
1 stop19h 29m
Frontier
Deal found 7/20$249
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:18 pm
CVG
-
DSM
2 stops12h 01m
Multiple Airlines
Sun 8/165:12 pm
DSM
-
CVG
1 stop23h 34m
Multiple Airlines
Deal found 7/19$254
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:51 pm
CVG
-
DSM
1 stop29h 17m
Multiple Airlines
Fri 9/182:51 pm
DSM
-
CVG
2 stops19h 52m
Multiple Airlines
Deal found 7/20$268
This Frontier deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:55 am
DTW
-
DSM
1 stop6h 39m
Frontier
Mon 9/72:19 pm
DSM
-
DTW
1 stop9h 54m
Frontier
Deal found 7/23$270
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:10 am
CLE
-
DSM
1 stop9h 52m
Multiple Airlines
Sun 11/18:00 am
DSM
-
CLE
2 stops28h 29m
Multiple Airlines
Deal found 7/22$283
This Priceline deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:40 am
DTW
-
DSM
1 stop6h 54m
Frontier
Mon 8/242:19 pm
DSM
-
DTW
1 stop9h 54m
Frontier
Deal found 7/20$284
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:45 am
CLE
-
DSM
1 stop10h 32m
Multiple Airlines
Mon 8/176:07 pm
DSM
-
CLE
1 stop28h 22m
Multiple Airlines
Deal found 7/21$287
This Priceline deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:40 am
DTW
-
DSM
1 stop6h 54m
Frontier
Fri 8/212:19 pm
DSM
-
DTW
1 stop9h 54m
Frontier
Deal found 7/22$294
This Frontier deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:30 pm
CVG
-
DSM
1 stop18h 04m
Frontier
Mon 9/142:51 pm
DSM
-
CVG
1 stop19h 29m
Frontier
Deal found 7/22$294
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:50 pm
DTW
-
DSM
1 stop7h 04m
Multiple Airlines
Sun 8/231:55 pm
DSM
-
DTW
2 stops34h 09m
Multiple Airlines
Deal found 7/20$302
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/199:00 am
CMH
-
DSM
1 stop6h 16m
United Airlines
Sat 8/226:00 am
DSM
-
CMH
1 stop4h 39m
United Airlines
Deal found 7/22$303
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:05 pm
PIT
-
DSM
1 stop8h 10m
Southwest
Mon 9/215:40 am
DSM
-
PIT
1 stop4h 05m
Southwest
Deal found 7/21$303

Find flight deals from Ohio to Des Moines

Keep the following information in mind while searching for Ohio to Des Moines flight deals. Data was last updated July 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$249
(Frontier)

One-way from

$100
(Frontier)

Popular in

June

Cheapest in

November

Average price

$493
Provider with most accurate pricing for Cleveland Hopkins Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Des Moines flights.
Search Deals
From Ohio to Des Moines
Search Deals
One-way flight from Ohio to Des Moines
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($79 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
Use the filters below to find and compare flights from Ohio to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Thu 8/20

7:05 am-10:43 am

1 stop4h 38m

Des Moines

Sun 8/23

6:35 pm-12:58 am

1 stop5h 23m

$303

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Thu 9/3

6:11 pm-9:23 pm

1 stop4h 12m

Des Moines

Mon 9/7

6:00 am-11:40 am

1 stop4h 40m

$303

PittsburghDes Moines

PIT - DSM

PITDSM

Pittsburgh

Mon 8/17

7:30 pm-10:10 pm

1 stop3h 40m

Des Moines

Thu 8/20

5:40 am-10:45 am

1 stop4h 05m

$303

CincinnatiDes Moines

CVG - DSM

CVGDSM

Cincinnati Cinci./N. Kentucky

Sat 9/12

2:05 pm-5:28 pm

1 stop4h 23m

Des Moines

Mon 9/14

3:22 pm-10:32 pm

1 stop6h 10m

$303

CincinnatiDes Moines

CVG - DSM

CVGDSM

Cincinnati Cinci./N. Kentucky

Thu 8/20

9:00 am-12:20 pm

1 stop4h 20m

Des Moines

Thu 8/27

1:21 pm-8:43 pm

1 stop6h 22m

$303

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Tue 9/15

7:30 pm-9:55 pm

1 stop3h 25m

Des Moines

Mon 9/21

5:40 am-1:45 pm

2 stops7h 05m

$308

PittsburghDes Moines

PIT - DSM

PITDSM

Pittsburgh

Thu 9/17

7:00 am-10:31 am

1 stop4h 31m

Des Moines

Mon 9/21

6:24 am-2:11 pm

2 stops6h 47m

$308

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Sat 8/22

3:06 pm-9:23 pm

2 stops7h 17m

Des Moines

Sat 8/29

3:20 pm-8:21 pm

1 stop4h 01m

$308

AkronDes Moines

CAK - DSM

CAKDSM

Akron/Canton

Sat 8/29

5:56 pm-11:10 pm

1 stop6h 14m

Des Moines

Sun 8/30

2:28 pm-8:26 pm

1 stop4h 58m

$309

AkronDes Moines

CAK - DSM

CAKDSM

Akron/Canton

Fri 9/4

6:09 pm-12:20 am

1 stop7h 11m

Des Moines

Mon 9/7

1:08 pm-9:49 pm

1 stop7h 41m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/20

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Ohio to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Des Moines

What is the cheapest month to book a flight from Ohio to Des Moines?

Currently, October is the cheapest month in which you can book a flight from Ohio to Des Moines (average of $334). Flying from Ohio to Des Moines in January is currently the most expensive (average of $577). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Ohio to Des Moines?

Airfare is below average for this route at the moment.
Ohio to Des Moines flights typically cost between $342 and $494 in October.
The cheapest round-trip price found within the last 5 days was $283 on Multiple Airlines (Oct 29-Nov 1).

Related info for your journey

Find useful and relevant information for your journey from Ohio to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Ohio?

    If you book a flight to Des Moines from Ohio, you will be flying to Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • How long is the flight from Ohio to Des Moines?

    There are many flights that can get you from Ohio to Des Moines in 3h 40m. Fly via Delta, United Airlines, or Southwest to get the fastest option. The distance between Ohio and Des Moines is about 702 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Ohio to Des Moines one-way?

    To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $118. American Airlines flights start at $118 while deals on Delta start at $118 one-way.

  • What are the most popular routes from Ohio to Des Moines?

    While some choose either Detroit Metropolitan Wayne County - Des Moines or Cincinnati Cinci./N. Kentucky - Des Moines, Columbus - Des Moines is the most popular route from Ohio to Des Moines.

  • Can I find deals for flights from Ohio to Des Moines that include hotel bookings?

    Yes. In addition to deals on Ohio to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Des Moines.

  • Can I find deals for business class flights from Ohio to Des Moines?

    Yes. Cheapflights offers flight deals from Ohio to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Des Moines?

    Currently, October is the cheapest month in which you can book a flight from Ohio to Des Moines (average of $334). Flying from Ohio to Des Moines in January is currently the most expensive (average of $577). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny

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Alternative routes for Ohio to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Ohio to Des Moines

Discover the top 4 airlines that operate flights from Ohio to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$361FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$400FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$249Average$409FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$319Average$446FlexibilityNo cancel feeOn-time63%

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