$174+ Cheap flights from Columbus (CMH) to Des Moines (DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — DSM
Oct 6 — Oct 131
Round-trip
1 adult, Economy
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Find cheap flights from Columbus to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbus to Des Moines
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Cheapest flights from Columbus to Des MoinesExplore the most affordable flight options available from Columbus to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.
Explore the most affordable flight options available from Columbus to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:17 am -
1 stop4h 14m
Thu 10/86:00 am -
1 stop4h 55m
Deal found 9/2![United Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:00 am -
1 stop4h 42m
Sat 10/174:01 pm -
1 stop6h 50m
Deal found 9/2![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:45 am -
1 stop4h 49m
Wed 9/306:00 am -
2 stops7h 08m
Deal found 9/1![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:00 am -
1 stop4h 42m
Fri 10/165:50 pm -
1 stop5h 08m
Deal found 9/2![Delta logo]()
$322
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:05 pm -
2 stops10h 00m
Wed 10/75:35 am -
1 stop5h 10m
Deal found 9/1![Southwest logo]()
$327
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:42 pm -
1 stop25h 26m
Mon 9/288:30 pm -
2 stops21h 25m
Deal found 9/2![Multiple Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:16 am -
1 stop4h 12m
Wed 11/187:23 am -
1 stop4h 43m
Deal found 9/4![American Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:00 am -
1 stop4h 31m
Sun 10/258:00 am -
1 stop4h 10m
Deal found 9/3![United Airlines logo]()
$348
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:45 pm -
2 stops7h 15m
Wed 11/183:30 pm -
1 stop4h 40m
Deal found 9/4![Southwest logo]()
$352
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:28 am -
1 stop4h 11m
Sun 10/45:57 pm -
1 stop5h 02m
Deal found 9/2![American Airlines logo]()
$353
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:24 am -
1 stop4h 32m
Sat 10/177:29 am -
1 stop5h 03m
Deal found 9/5![American Airlines logo]()
$355
Best flights from Columbus to Des MoinesDiscover carefully curated flight deals from Columbus to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 6, 2026.
Discover carefully curated flight deals from Columbus to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 6, 2026.
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:45 am -
1 stop4h 49m
Wed 9/303:11 pm -
1 stop4h 23m
Deal found 9/1![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:50 am -
1 stop6h 58m
Wed 10/76:00 am -
1 stop4h 15m
Deal found 9/1![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:45 pm -
2 stops7h 15m
Wed 11/186:00 am -
2 stops10h 25m
Deal found 9/4![Southwest logo]()
$357
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:17 am -
1 stop4h 14m
Sun 10/186:55 pm -
1 stop3h 59m
Deal found 9/3![United Airlines logo]()
$361
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/196:40 am -
1 stop6h 11m
Sun 12/206:42 pm -
1 stop4h 51m
Deal found 9/3![Delta logo]()
$400
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/281:10 pm -
2 stops10h 05m
Wed 9/306:10 am -
2 stops10h 45m
Deal found 9/1![Southwest logo]()
$408
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:36 pm -
2 stops12h 12m
Wed 10/216:55 pm -
1 stop3h 59m
Deal found 9/2![United Airlines logo]()
$394
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:02 am -
2 stops7h 32m
Sat 10/173:11 pm -
2 stops7h 48m
Deal found 9/2![United Airlines logo]()
$399
Last-minute flights from Columbus to Des MoinesDiscover last-minute flight deals from Columbus to Des Moines. Data last updated September 6, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to Des Moines. Data last updated September 6, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:42 pm -
1 stop20h 27m
Fri 9/253:04 pm -
2 stops26h 23m
Deal found 9/2![Multiple Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:42 pm -
1 stop25h 26m
Mon 9/288:30 pm -
2 stops21h 25m
Deal found 9/2![Multiple Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:42 pm -
1 stop25h 26m
Thu 10/18:10 am -
2 stops33h 45m
Deal found 9/2![Multiple Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:45 am -
1 stop4h 49m
Wed 9/306:00 am -
2 stops7h 08m
Deal found 9/1![United Airlines logo]()
$314
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:05 pm -
2 stops10h 00m
Wed 10/75:35 am -
1 stop5h 10m
Deal found 9/1![Southwest logo]()
$327
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:28 am -
1 stop4h 11m
Sun 10/45:57 pm -
1 stop5h 02m
Deal found 9/2![American Airlines logo]()
$353
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:17 am -
1 stop4h 14m
Thu 10/86:00 am -
1 stop4h 55m
Deal found 9/2![United Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:00 am -
1 stop4h 42m
Fri 10/165:50 pm -
1 stop5h 08m
Deal found 9/2![Delta logo]()
$322
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:00 am -
1 stop4h 42m
Sat 10/174:01 pm -
1 stop6h 50m
Deal found 9/2![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:24 am -
1 stop4h 32m
Sat 10/177:29 am -
1 stop5h 03m
Deal found 9/5![American Airlines logo]()
$355
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:00 am -
1 stop4h 31m
Sun 10/258:00 am -
1 stop4h 10m
Deal found 9/3![United Airlines logo]()
$348
One-way flights from Columbus to Des MoinesSearch for one-way flight options from Columbus to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 6, 2026.
Search for one-way flight options from Columbus to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 6, 2026.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:46 am -
1 stop4h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![American Airlines logo]()
$174
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2512:10 pm -
2 stops11h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Southwest logo]()
$231
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:00 am -
1 stop4h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![United Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:30 am -
3 stops57h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$250
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:05 pm -
2 stops10h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Southwest logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:28 am -
3 stops27h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$459
Find flight deals from Columbus to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Columbus (CMH) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $304 (United Airlines) |
One-way from | $174 (American Airlines) |
Popular in | February |
Cheapest in | December |
Average price | $361 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 6, 2026.
Use the filters below to find and compare flights from Columbus Airport to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ColumbusDes Moines
CMH Columbus - DSM Des Moines
CMHDSM
Columbus
Wed 11/25
5:46 am-9:00 am
1 stop4h 14m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$174
ColumbusDes Moines
CMH Columbus - DSM Des Moines
CMHDSM
Columbus
Wed 11/25
12:10 pm-10:30 pm
2 stops11h 20m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$231
ColumbusDes Moines
CMH Columbus - DSM Des Moines
CMHDSM
Columbus
Fri 9/18
9:00 am-12:16 pm
1 stop4h 16m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$239
ColumbusDes Moines
CMH Columbus - DSM Des Moines
CMHDSM
Columbus
Fri 9/18
1:05 pm-10:15 pm
2 stops10h 10m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$265
ColumbusDes Moines
CMH Columbus - DSM Des Moines
CMHDSM
Columbus
Mon 9/28
8:45 am-12:34 pm
1 stop4h 49m
Des Moines
Wed 9/30
3:11 pm-8:34 pm
1 stop4h 23m
$309
ColumbusDes Moines
CMH Columbus - DSM Des Moines
CMHDSM
Columbus
Wed 9/30
10:50 am-4:48 pm
1 stop6h 58m
Des Moines
Wed 10/7
6:00 am-11:15 am
1 stop4h 15m
$309
ColumbusDes Moines
CMH Columbus - DSM Des Moines
CMHDSM
Columbus
Tue 11/17
3:45 pm-10:00 pm
2 stops7h 15m
Des Moines
Wed 11/18
6:00 am-5:25 pm
2 stops10h 25m
$357
ColumbusDes Moines
CMH Columbus - DSM Des Moines
CMHDSM
Columbus
Fri 10/16
7:17 am-10:31 am
1 stop4h 14m
Des Moines
Sun 10/18
6:55 pm-11:54 pm
1 stop3h 59m
$361
ColumbusDes Moines
CMH Columbus - DSM Des Moines
CMHDSM
Columbus
Tue 10/20
12:36 pm-11:48 pm
2 stops12h 12m
Des Moines
Wed 10/21
6:55 pm-11:54 pm
1 stop3h 59m
$394
ColumbusDes Moines
CMH Columbus - DSM Des Moines
CMHDSM
Columbus
Wed 10/14
6:02 am-12:34 pm
2 stops7h 32m
Des Moines
Sat 10/17
3:11 pm-11:59 pm
2 stops7h 48m
$399
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Columbus to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbus to Des Moines in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Columbus Airport-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbus Airport-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbus Airport-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Columbus Airport-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbus Airport-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Columbus to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Columbus with our price prediction graph.
CMH-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to Des Moines
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 6, 2026.
Read through reviews of airlines operating flights from Columbus Airport to Des Moines, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Boarding
8.1
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Boarding
8.1
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Boarding
8.1
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Boarding
8.1
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Columbus to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Other flights to Des Moines
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Columbus and Des Moines flights
Browse other Columbus and Des Moines flight options. Last updated on September 6, 2026.
Other flights from Columbus
Browse through other flights departing from Columbus. Flights are based on user searches made on Cheapflights and were last updated on September 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Columbus to Des Moines
Discover the top 4 airlines that operate flights from Columbus to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$203 | Average$371 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$256 | Average$481 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$296 | Average$391 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$302 | Average$416 | FlexibilityNo cancel fee | On-time63% |