$56+ Cheap flights from Cleveland to St. Louis (CLE - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — STL
Oct 21 — Oct 281
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Cleveland to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Cleveland Hopkins Intl to Lambert-St Louis are usually found in October or July, booked 83 days in advance, depart on a Saturday or Wednesday and return on a Wednesday
Cheap flight deals from Cleveland to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Cleveland to St. LouisExplore the most affordable flight options available from Cleveland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from Cleveland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:00 am -
1 stop11h 40m
Wed 11/116:44 pm -
1 stop16h 32m
Deal found 9/19![Frontier logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:46 pm -
1 stop26h 54m
Wed 10/216:35 pm -
1 stop16h 34m
Deal found 9/19![Frontier logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:00 am -
1 stop11h 40m
Mon 11/96:44 pm -
1 stop16h 32m
Deal found 9/19![Frontier logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:46 pm -
1 stop26h 54m
Mon 10/196:35 pm -
1 stop25h 17m
Deal found 9/19![Frontier logo]()
$116
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:10 am -
Nonstop1h 35m
Mon 10/127:55 pm -
Nonstop1h 35m
Deal found 9/18![Southwest logo]()
$117
This Frontier deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/101:20 pm -
1 stop10h 53m
Sat 10/174:30 pm -
1 stop6h 49m
Deal found 9/18![Frontier logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:00 am -
1 stop11h 40m
Fri 11/66:44 pm -
1 stop17h 50m
Deal found 9/19![Frontier logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:00 am -
1 stop11h 40m
Fri 11/66:44 pm -
1 stop17h 50m
Deal found 9/19![Frontier logo]()
$126
Best flights from Cleveland to St. LouisDiscover carefully curated flight deals from Cleveland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from Cleveland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:25 pm -
1 stop4h 00m
Sat 10/174:55 pm -
Nonstop1h 40m
Deal found 9/19![Southwest logo]()
$127
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:10 am -
Nonstop1h 35m
Mon 10/125:40 pm -
1 stop5h 10m
Deal found 9/18![Southwest logo]()
$127
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:50 pm -
Nonstop1h 35m
Mon 10/267:55 pm -
Nonstop1h 35m
Deal found 9/19![Southwest logo]()
$213
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:50 pm -
2 stops7h 10m
Wed 11/187:35 am -
2 stops7h 35m
Deal found 9/16![Southwest logo]()
$241
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:05 am -
Nonstop1h 40m
Wed 11/1810:30 am -
Nonstop1h 35m
Deal found 9/16![Southwest logo]()
$244
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:10 pm -
Nonstop1h 50m
Tue 11/172:25 pm -
1 stop5h 00m
Deal found 9/16![Southwest logo]()
$256
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:05 am -
Nonstop1h 35m
Sat 10/3110:15 am -
Nonstop1h 35m
Deal found 9/17![Southwest logo]()
$276
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:50 pm -
Nonstop1h 35m
Mon 10/267:55 pm -
Nonstop1h 35m
Deal found 9/16![Southwest logo]()
$279
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:35 pm -
1 stop7h 35m
Sun 11/88:40 pm -
Nonstop1h 35m
Deal found 9/17![Southwest logo]()
$285
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:05 am -
Nonstop1h 35m
Sun 11/14:30 pm -
1 stop5h 20m
Deal found 9/18![Southwest logo]()
$287
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:05 am -
Nonstop1h 40m
Wed 11/256:30 pm -
1 stop3h 55m
Deal found 9/16![Southwest logo]()
$297
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/294:00 pm -
1 stop8h 50m
Sun 11/11:25 pm -
2 stops8h 25m
Deal found 9/17![Southwest logo]()
$300
Last-minute flights from Cleveland to St. LouisDiscover last-minute flight deals from Cleveland to St. Louis. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from Cleveland to St. Louis. Data last updated September 21, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:10 am -
Nonstop1h 35m
Mon 10/127:55 pm -
Nonstop1h 35m
Deal found 9/18![Southwest logo]()
$117
This Frontier deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/101:20 pm -
1 stop10h 53m
Sat 10/174:30 pm -
1 stop6h 49m
Deal found 9/18![Frontier logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:46 pm -
1 stop26h 54m
Wed 10/216:35 pm -
1 stop16h 34m
Deal found 9/19![Frontier logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:46 pm -
1 stop26h 54m
Mon 10/196:35 pm -
1 stop25h 17m
Deal found 9/19![Frontier logo]()
$116
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:10 am -
Nonstop1h 35m
Wed 10/148:30 am -
2 stops7h 15m
Deal found 9/18![Southwest logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:46 pm -
1 stop26h 54m
Wed 10/216:35 pm -
1 stop16h 34m
Deal found 9/19![Frontier logo]()
$133
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:40 pm -
1 stop3h 40m
Mon 10/195:40 pm -
1 stop5h 10m
Deal found 9/20![Southwest logo]()
$137
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:35 am -
Nonstop1h 35m
Sat 10/315:20 am -
2 stops12h 00m
Deal found 9/20![Southwest logo]()
$138
One-way flights from Cleveland to St. LouisSearch for one-way flight options from Cleveland to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
Search for one-way flight options from Cleveland to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:46 pm -
1 stop26h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Frontier logo]()
$56
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:10 am -
Nonstop1h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Southwest logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/183:46 pm -
1 stop27h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Frontier logo]()
$63
This Super.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
1 stop18h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Frontier logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:46 pm -
1 stop26h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$68
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/139:59 pm -
2 stops20h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:59 pm -
2 stops20h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Frontier logo]()
$73
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1410:46 am -
1 stop6h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Delta logo]()
$74
Find flight deals from Cleveland to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $108 (Kiwi.com) |
One-way from | $56 (Kiwi.com) |
Popular in | January |
Cheapest in | October |
Average price | $335 |
Good round-trip deal | $319 or less |
Good one-way deal | $183 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Cleveland to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from Cleveland to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ClevelandSt. Louis
CLE Cleveland Hopkins Intl - STL Lambert-St Louis
CLESTL
Cleveland Hopkins Intl
Thu 11/19
7:05 am-7:45 am
Nonstop1h 40m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$59
ClevelandSt. Louis
CLE Cleveland Hopkins Intl - STL Lambert-St Louis
CLESTL
Cleveland Hopkins Intl
Thu 10/15
6:10 am-9:49 am
1 stop4h 39m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$79
ClevelandSt. Louis
CLE Cleveland Hopkins Intl - STL Lambert-St Louis
CLESTL
Cleveland Hopkins Intl
Wed 10/14
10:27 am-1:53 pm
1 stop4h 26m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$116
ClevelandSt. Louis
CLE Cleveland Hopkins Intl - STL Lambert-St Louis
CLESTL
Cleveland Hopkins Intl
Sat 10/10
5:25 pm-8:25 pm
1 stop4h 00m
Lambert-St Louis
Sat 10/17
4:55 pm-7:35 pm
Nonstop1h 40m
$127
ClevelandSt. Louis
CLE Cleveland Hopkins Intl - STL Lambert-St Louis
CLESTL
Cleveland Hopkins Intl
Sat 10/10
7:10 am-7:45 am
Nonstop1h 35m
Lambert-St Louis
Mon 10/12
5:40 pm-11:50 pm
1 stop5h 10m
$127
ClevelandSt. Louis
CLE Cleveland Hopkins Intl - STL Lambert-St Louis
CLESTL
Cleveland Hopkins Intl
Sat 11/14
10:46 am-3:47 pm
1 stop6h 01m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$146
Quickest round-trip
ClevelandSt. Louis
CLE Cleveland Hopkins Intl - STL Lambert-St Louis
CLESTL
Cleveland Hopkins Intl
Mon 10/19
4:50 pm-5:25 pm
Nonstop1h 35m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$155
ClevelandSt. Louis
CLE Cleveland Hopkins Intl - STL Lambert-St Louis
CLESTL
Cleveland Hopkins Intl
Sun 11/1
8:10 pm-9:00 pm
Nonstop1h 50m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$155
ClevelandSt. Louis
CLE Cleveland Hopkins Intl - STL Lambert-St Louis
CLESTL
Cleveland Hopkins Intl
Sun 10/25
8:20 pm-8:55 pm
Nonstop1h 35m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$155
ClevelandSt. Louis
CLE Cleveland Hopkins Intl - STL Lambert-St Louis
CLESTL
Cleveland Hopkins Intl
Thu 10/15
4:50 pm-5:25 pm
Nonstop1h 35m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$155
Showing 1-10 of 23 resultsSorted by cheapest first
Compare providers for flights from Cleveland to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Cleveland to St. Louis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Cleveland-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Cleveland-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Cleveland-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Cleveland-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cleveland-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Cleveland to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Cleveland with our price prediction graph.
CLE-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Cleveland to St. Louis
Prices
Airlines
How far ahead should I book a flight from Cleveland to St. Louis?
To ensure you get the cheapest price possible for a flight from Cleveland to St. Louis, you should look to book at least 82 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Cleveland to St. Louis?
Currently, October is the cheapest month in which you can book a flight from Cleveland to St. Louis (average of $230). Flying from Cleveland to St. Louis in January is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CLE to STL?
Find hourly flight availability from Cleveland to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 21, 2026.
One of the essential ways to save on airfare from Cleveland to St. Louis is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 33% on airfare.
The best insider tips for Cleveland to St. Louis flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Cleveland to St. Louis trip
Our travel experts
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 21, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Cleveland to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Cleveland to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Maryland Heights
Collinsville
Edwardsville
Glencoe
Chesterfield
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Cleveland
Popular flights
St. Louis flight routes
Alternative routes for Cleveland to St. Louis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Cleveland to St. Louis by cabin class
Find flights from Cleveland to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Cleveland and St. Louis flights
Browse other Cleveland and St. Louis flight options. Last updated on September 21, 2026.
Other flights from Cleveland
Browse through other flights departing from Cleveland. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Top 5 airlines flying from Cleveland to St. Louis
Discover the top 5 airlines that operate flights from Cleveland to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$99 | Average$366 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$124 | Average$230 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$167 | Average$353 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$210 | Average$377 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$228 | Average$366 | FlexibilityNo cancel fee | On-time71% |