$79+ Cheap flights from Detroit Metropolitan Wayne County Airport to St. Louis (DTW - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — STL
Dec 4 — Dec 111
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Lambert-St Louis are usually found in September or August, booked 35 days in advance, depart on a Saturday or Thursday and return on a Saturday
Cheap flight deals from Detroit to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to St. LouisExplore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
Explore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:08 pm -
1 stop18h 02m
Fri 12/412:02 pm -
1 stop7h 46m
Deal found 11/1![Frontier logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/32:27 pm -
2 stops21h 50m
Wed 12/912:02 pm -
1 stop24h 45m
Deal found 11/1![Frontier logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:35 am -
2 stops25h 42m
Mon 12/77:54 pm -
1 stop28h 16m
Deal found 11/3![Frontier logo]()
$195
This Trip.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:40 pm -
1 stop11h 32m
Mon 12/77:54 pm -
1 stop28h 16m
Deal found 11/3![Frontier logo]()
$206
This Expedia deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop7h 25m
Fri 12/412:02 pm -
1 stop7h 46m
Deal found 10/30![Frontier logo]()
$213
This CheapOair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:39 pm -
1 stop16h 27m
Tue 12/86:20 pm -
1 stop18h 48m
Deal found 11/3![Frontier logo]()
$218
This Expedia deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:25 am -
1 stop12h 17m
Wed 11/251:20 pm -
1 stop20h 12m
Deal found 11/2![Frontier logo]()
$220
Best flights from Detroit to St. LouisDiscover carefully curated flight deals from Detroit to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
Discover carefully curated flight deals from Detroit to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/299:15 am -
Nonstop1h 50m
Fri 1/16:20 am -
Nonstop1h 42m
Deal found 11/3![Delta logo]()
$315
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:55 am -
Nonstop1h 50m
Tue 12/225:05 pm -
1 stop6h 30m
Deal found 10/31![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:26 am -
1 stop5h 44m
Sat 11/286:50 pm -
1 stop4h 07m
Deal found 10/30![United Airlines logo]()
$393
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:45 pm -
Nonstop1h 47m
Wed 12/92:17 pm -
Nonstop1h 36m
Deal found 11/3![Delta logo]()
$315
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:55 am -
Nonstop1h 50m
Wed 12/98:25 am -
1 stop7h 55m
Deal found 11/3![Southwest logo]()
$325
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:15 am -
1 stop5h 05m
Mon 11/236:40 am -
2 stops9h 35m
Deal found 10/31![Southwest logo]()
$340
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:45 pm -
1 stop5h 20m
Sun 12/136:05 pm -
Nonstop1h 40m
Deal found 11/1![Delta logo]()
$353
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:40 am -
2 stops10h 40m
Wed 11/256:30 pm -
1 stop4h 10m
Deal found 11/1![Southwest logo]()
$365
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/188:20 am -
2 stops6h 35m
Sun 12/2010:35 am -
1 stop5h 05m
Deal found 10/31![Southwest logo]()
$368
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:40 am -
Nonstop1h 55m
Mon 12/287:55 pm -
Nonstop1h 35m
Deal found 11/1![Southwest logo]()
$403
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:15 pm -
Nonstop1h 45m
Mon 11/307:55 pm -
Nonstop1h 35m
Deal found 10/31![Southwest logo]()
$403
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:40 am -
Nonstop1h 55m
Sun 12/277:55 pm -
Nonstop1h 35m
Deal found 11/1![Southwest logo]()
$403
Last-minute flights from Detroit to St. LouisDiscover last-minute flight deals from Detroit to St. Louis. Data last updated November 4, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to St. Louis. Data last updated November 4, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:25 am -
1 stop12h 17m
Wed 11/251:20 pm -
1 stop20h 12m
Deal found 11/2![Frontier logo]()
$220
This Expedia deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop7h 25m
Fri 12/412:02 pm -
1 stop7h 46m
Deal found 10/30![Frontier logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:08 pm -
1 stop18h 02m
Fri 12/412:02 pm -
1 stop7h 46m
Deal found 11/1![Frontier logo]()
$150
This CheapOair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:39 pm -
1 stop16h 27m
Tue 12/86:20 pm -
1 stop18h 48m
Deal found 11/3![Frontier logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/32:27 pm -
2 stops21h 50m
Wed 12/912:02 pm -
1 stop24h 45m
Deal found 11/1![Frontier logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:35 am -
2 stops25h 42m
Mon 12/77:54 pm -
1 stop28h 16m
Deal found 11/3![Frontier logo]()
$195
This Trip.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:40 pm -
1 stop11h 32m
Mon 12/77:54 pm -
1 stop28h 16m
Deal found 11/3![Frontier logo]()
$206
One-way flights from Detroit to St. LouisSearch for one-way flight options from Detroit to St. Louis. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
Search for one-way flight options from Detroit to St. Louis. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/148:01 pm -
2 stops40h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Frontier logo]()
$79
This Orbitz deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/258:05 pm -
1 stop28h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:28 pm -
2 stops23h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Frontier logo]()
$113
This Frontier deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/231:33 pm -
1 stop5h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Frontier logo]()
$118
This CheapOair deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:34 pm -
1 stop16h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Frontier logo]()
$126
This Frontier deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:15 am -
1 stop10h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Frontier logo]()
$127
This CheapOair deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:35 pm -
1 stop19h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Frontier logo]()
$128
This Frontier deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:41 am -
1 stop10h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Frontier logo]()
$140
Find flight deals from Detroit to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $150 (Kiwi.com) |
One-way from | $79 (Kiwi.com) |
Popular in | January |
Cheapest in | September |
Average price | $405 |
Good round-trip deal | $316 or less |
Good one-way deal | $189 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Fri 12/18
7:51 am-3:26 pm
1 stop8h 35m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$140
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Wed 12/16
12:07 pm-12:41 am
2 stops37h 34m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$142
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Wed 12/16
6:55 am-7:45 am
Nonstop1h 50m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$158
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Fri 11/27
8:15 pm-9:00 pm
Nonstop1h 45m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$158
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Fri 12/18
8:15 pm-9:00 pm
Nonstop1h 45m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$158
Quickest round-trip
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Thu 1/21
5:15 pm-5:55 pm
Nonstop1h 40m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$158
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Wed 11/25
9:00 pm-6:55 am
2 stops10h 55m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$179
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Sun 11/22
8:15 pm-9:00 pm
Nonstop1h 45m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$186
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Sun 12/20
6:40 am-7:35 am
Nonstop1h 55m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$186
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Tue 12/15
6:20 pm-7:10 pm
Nonstop1h 50m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$193
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Detroit to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to St. Louis in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Detroit with our price prediction graph.
DTW-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to St. Louis
Prices
Airlines
How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to St. Louis?
The price you pay for your flight from Detroit Metropolitan Wayne County Airport to St. Louis may vary depending on when you book. For the best chance of a lower fare, look to book 34 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to St. Louis?
Currently, September is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to St. Louis (average of $299). Flying from Detroit Metropolitan Wayne County Airport to St. Louis in January is currently the most expensive (average of $479). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTW to STL?
Find hourly flight availability from Detroit to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 4, 2026.
Unlike in the morning, when flights are generally more expensive, you can save up to 21% on flights from Detroit Metropolitan Wayne County Airport to St. Louis by exploring options for tickets at noon.
What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to St. Louis?
Use this chart to determine the cheapest time to fly round-trip from Detroit to St. Louis. Price data was last updated on October 31, 2026.
Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to St. Louis flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
The best insider tips for Detroit Metropolitan Wayne County Airport to St. Louis flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Detroit Metropolitan Wayne County Airport to St. Louis trip
Our travel experts
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated November 4, 2026.
Read reviews from past customers who have flown Southwest,Delta, andFrontier from Detroit Metropolitan Wayne County Airport to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Detroit to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Maryland Heights
Chesterfield
Edwardsville
Glencoe
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Detroit and St. Louis flights
Browse other Detroit and St. Louis flight options. Last updated on November 4, 2026.
Other flights from Detroit
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Other flights to St. Louis
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Top 3 airlines flying from Detroit to St. Louis
Discover the top 3 airlines that operate flights from Detroit to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$177 | Average$403 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$181 | Average$348 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$215 | Average$363 | FlexibilityNo cancel fee | On-time63% |