$253+ Cheap flights from Manchester, NH to Des Moines (MHT - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/30. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — DSM
May 31 — Jun 71
Round-trip
1 adult, Economy
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Find cheap flights from Manchester to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Manchester to Des Moines
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Best
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Cheapest flights from Manchester to Des MoinesExplore the most affordable flight options available from Manchester to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
Explore the most affordable flight options available from Manchester to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:10 pm
MHT
- DSM
1 stop8h 07m
American Airlines
Mon 6/15:00 am
DSM
- MHT
1 stop5h 50m
American Airlines
Deal found 5/1![American Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:35 am
MHT
- DSM
1 stop6h 25m
American Airlines
Mon 6/15:00 am
DSM
- MHT
1 stop5h 50m
American Airlines
Deal found 5/1![American Airlines logo]()
$416
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:20 pm
MHT
- DSM
1 stop5h 49m
American Airlines
Thu 11/52:16 pm
DSM
- MHT
1 stop7h 36m
American Airlines
Deal found 4/27![American Airlines logo]()
$427
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:25 am
MHT
- DSM
2 stops8h 37m
United Airlines
Wed 8/1911:34 am
DSM
- MHT
2 stops11h 22m
United Airlines
Deal found 4/27![United Airlines logo]()
$452
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:30 pm
MHT
- DSM
2 stops10h 31m
United Airlines
Thu 11/55:00 am
DSM
- MHT
2 stops9h 03m
United Airlines
Deal found 4/27![United Airlines logo]()
$473
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:50 am
MHT
- DSM
2 stops14h 10m
Southwest
Thu 11/55:25 am
DSM
- MHT
1 stop10h 15m
Southwest
Deal found 4/27![Southwest logo]()
$478
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:25 pm
MHT
- DSM
1 stop4h 45m
Southwest
Sun 8/95:40 am
DSM
- MHT
1 stop6h 55m
Southwest
Deal found 4/28![Southwest logo]()
$493
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:45 am
MHT
- DSM
1 stop7h 18m
American Airlines
Fri 8/71:12 pm
DSM
- MHT
1 stop7h 53m
American Airlines
Deal found 4/27![American Airlines logo]()
$507
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:45 am
MHT
- DSM
2 stops10h 50m
Southwest
Fri 8/73:50 pm
DSM
- MHT
1 stop4h 35m
Southwest
Deal found 4/27![Southwest logo]()
$542
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:25 am
MHT
- DSM
2 stops8h 55m
Southwest
Mon 6/14:20 pm
DSM
- MHT
1 stop4h 35m
Southwest
Deal found 5/1![Southwest logo]()
$558
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:10 pm
MHT
- DSM
1 stop8h 07m
American Airlines
Sun 5/318:02 pm
DSM
- MHT
1 stop14h 48m
American Airlines
Deal found 4/27![American Airlines logo]()
$561
Best flights from Manchester to Des MoinesDiscover carefully curated flight deals from Manchester to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
Discover carefully curated flight deals from Manchester to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:25 am
MHT
- DSM
2 stops8h 37m
United Airlines
Wed 8/193:24 pm
DSM
- MHT
2 stops7h 32m
United Airlines
Deal found 4/30![United Airlines logo]()
$452
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:25 am
MHT
- DSM
2 stops8h 55m
Southwest
Mon 6/14:20 pm
DSM
- MHT
1 stop4h 35m
Southwest
Deal found 5/1![Southwest logo]()
$558
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:45 am
MHT
- DSM
2 stops10h 50m
Southwest
Fri 8/75:40 am
DSM
- MHT
2 stops11h 05m
Southwest
Deal found 4/27![Southwest logo]()
$589
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:10 pm
MHT
- DSM
2 stops10h 45m
Southwest
Mon 6/15:25 am
DSM
- MHT
2 stops8h 15m
Southwest
Deal found 5/1![Southwest logo]()
$606
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:31 pm
MHT
- DSM
2 stops16h 06m
United Airlines
Tue 5/198:00 am
DSM
- MHT
2 stops9h 56m
United Airlines
Deal found 4/30![United Airlines logo]()
$806
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:40 am
MHT
- DSM
2 stops9h 05m
Southwest
Sun 8/95:40 am
DSM
- MHT
2 stops10h 50m
Southwest
Deal found 4/28![Southwest logo]()
$747
Last-minute flights from Manchester to Des MoinesDiscover last-minute flight deals from Manchester to Des Moines. Data last updated May 1, 2026 and is based on user searches.
Discover last-minute flight deals from Manchester to Des Moines. Data last updated May 1, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:31 pm
MHT
- DSM
2 stops16h 06m
United Airlines
Tue 5/198:00 am
DSM
- MHT
2 stops9h 56m
United Airlines
Deal found 4/30![United Airlines logo]()
$806
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:35 am
MHT
- DSM
1 stop6h 25m
American Airlines
Mon 6/15:00 am
DSM
- MHT
1 stop5h 50m
American Airlines
Deal found 5/1![American Airlines logo]()
$416
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:10 pm
MHT
- DSM
1 stop8h 07m
American Airlines
Sun 5/318:02 pm
DSM
- MHT
1 stop14h 48m
American Airlines
Deal found 4/27![American Airlines logo]()
$561
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:10 pm
MHT
- DSM
2 stops10h 55m
Southwest
Mon 6/14:20 pm
DSM
- MHT
1 stop4h 35m
Southwest
Deal found 5/1![Southwest logo]()
$588
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:10 pm
MHT
- DSM
1 stop4h 55m
Southwest
Sun 5/316:40 am
DSM
- MHT
2 stops10h 45m
Southwest
Deal found 5/1![Southwest logo]()
$988
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:37 pm
MHT
- DSM
2 stops10h 07m
United Airlines
Mon 6/18:00 am
DSM
- MHT
3 stops10h 02m
United Airlines
Deal found 5/1![United Airlines logo]()
$1,225
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:10 pm
MHT
- DSM
1 stop8h 07m
American Airlines
Mon 6/15:00 am
DSM
- MHT
1 stop5h 50m
American Airlines
Deal found 5/1![American Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:25 am
MHT
- DSM
2 stops8h 55m
Southwest
Mon 6/14:20 pm
DSM
- MHT
1 stop4h 35m
Southwest
Deal found 5/1![Southwest logo]()
$558
One-way flights from Manchester to Des MoinesSearch for one-way flight options from Manchester to Des Moines. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
Search for one-way flight options from Manchester to Des Moines. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/309:25 am
MHT
- DSM
2 stops11h 00m
United Airlines
Deal found 4/28![United Airlines logo]()
$253
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/49:25 am
MHT
- DSM
2 stops12h 05m
United Airlines
Deal found 4/27![United Airlines logo]()
$534
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:36 pm
MHT
- DSM
2 stops10h 08m
United Airlines
Deal found 4/27![United Airlines logo]()
$715
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/182:43 pm
MHT
- DSM
2 stops9h 18m
United Airlines
Deal found 4/28![United Airlines logo]()
$915
Find flight deals from Manchester to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $405 (American Airlines) |
One-way from | $253 (United Airlines) |
Popular in | February |
Cheapest in | December |
Average price | $299 |
Cheapflights Fare Finder
Customize your flight search to find flights from Manchester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from Manchester to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Tue 8/18
9:25 am-5:02 pm
2 stops8h 37m
Des Moines
Wed 8/19
3:24 pm-11:56 pm
2 stops7h 32m
$452
Quickest round-trip
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Sat 5/30
5:25 am-1:20 pm
2 stops8h 55m
Des Moines
Mon 6/1
4:20 pm-9:55 pm
1 stop4h 35m
$558
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Sun 6/7
5:45 am-3:35 pm
2 stops10h 50m
Des Moines
Fri 8/7
5:40 am-5:45 pm
2 stops11h 05m
$589
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Fri 5/29
12:10 pm-9:55 pm
2 stops10h 45m
Des Moines
Mon 6/1
5:25 am-2:40 pm
2 stops8h 15m
$606
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Fri 8/7
5:40 am-1:45 pm
2 stops9h 05m
Des Moines
Sun 8/9
5:40 am-5:30 pm
2 stops10h 50m
$747
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Fri 5/15
7:31 pm-10:37 am
2 stops16h 06m
Des Moines
Tue 5/19
8:00 am-6:56 pm
2 stops9h 56m
$806
Cheapest one-way
Quickest one-way
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Wed 5/13
2:36 pm-11:44 pm
2 stops10h 08m
$715
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Sun 10/18
9:25 am-7:25 pm
2 stops11h 00m
$915
Sorted by cheapest first
Compare providers for flights from Manchester to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to Des Moines in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Manchester, New Hampshire-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Manchester, New Hampshire-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Manchester, New Hampshire-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Manchester to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Manchester with our price prediction graph.
MHT-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated May 1, 2026.
Get a feel of what it's like to fly with American Airlines from Manchester to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.1
Boarding
7.5
Entertainment
6.9
Food
6.4
Comfort
7.2
Crew
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Overall
7.1
Boarding
7.5
Entertainment
6.9
Food
6.4
Comfort
7.2
Crew
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Related info for your journey
Find useful and relevant information for your journey from Manchester to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny
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Manchester and Des Moines flights
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Top airline flying from Manchester to Des Moines
Discover the top airline that operate flights from Manchester to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$316 | Average$512 | FlexibilityNo cancel fee | On-time71% |