$167+ Cheap flights from Manchester, NH to Des Moines (MHT - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — DSM
Jul 15 — Jul 221
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Manchester to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Manchester to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Manchester to Des MoinesExplore the most affordable flight options available from Manchester to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 15, 2026.
Explore the most affordable flight options available from Manchester to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 15, 2026.
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:35 am
MHT
- DSM
1 stop5h 59m
American Airlines
Tue 7/212:41 pm
DSM
- MHT
1 stop8h 07m
American Airlines
Deal found 6/14![American Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:18 pm
MHT
- DSM
1 stop6h 43m
American Airlines
Tue 8/45:00 am
DSM
- MHT
1 stop5h 31m
American Airlines
Deal found 6/13![American Airlines logo]()
$380
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:46 pm
MHT
- DSM
2 stops9h 58m
United Airlines
Wed 9/26:00 am
DSM
- MHT
2 stops12h 00m
United Airlines
Deal found 6/14![United Airlines logo]()
$433
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:00 pm
MHT
- DSM
1 stop5h 35m
Southwest
Wed 7/295:20 am
DSM
- MHT
1 stop4h 30m
Southwest
Deal found 6/12![Southwest logo]()
$485
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:00 pm
MHT
- DSM
1 stop5h 35m
Southwest
Mon 8/34:40 pm
DSM
- MHT
1 stop4h 20m
Southwest
Deal found 6/12![Southwest logo]()
$493
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/197:10 pm
MHT
- DSM
1 stop5h 40m
Southwest
Fri 7/245:10 am
DSM
- MHT
1 stop4h 40m
Southwest
Deal found 6/13![Southwest logo]()
$497
Best flights from Manchester to Des MoinesDiscover carefully curated flight deals from Manchester to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 15, 2026.
Discover carefully curated flight deals from Manchester to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 15, 2026.
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:14 am
MHT
- DSM
1 stop6h 51m
American Airlines
Tue 7/211:35 pm
DSM
- MHT
2 stops9h 13m
American Airlines
Deal found 6/14![American Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:46 pm
MHT
- DSM
2 stops9h 58m
United Airlines
Wed 9/26:00 am
DSM
- MHT
2 stops12h 00m
United Airlines
Deal found 6/14![United Airlines logo]()
$433
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/197:10 pm
MHT
- DSM
1 stop5h 40m
Southwest
Fri 7/244:40 pm
DSM
- MHT
2 stops6h 30m
Southwest
Deal found 6/13![Southwest logo]()
$502
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:18 pm
MHT
- DSM
1 stop6h 43m
American Airlines
Tue 8/45:00 am
DSM
- MHT
2 stops10h 40m
American Airlines
Deal found 6/13![American Airlines logo]()
$385
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:30 pm
MHT
- DSM
2 stops10h 31m
United Airlines
Wed 10/2811:30 am
DSM
- MHT
2 stops11h 29m
United Airlines
Deal found 6/15![United Airlines logo]()
$433
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2712:30 pm
MHT
- DSM
2 stops10h 55m
Southwest
Wed 7/295:20 am
DSM
- MHT
2 stops9h 00m
Southwest
Deal found 6/12![Southwest logo]()
$558
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:18 pm
MHT
- DSM
1 stop6h 43m
American Airlines
Thu 7/305:00 am
DSM
- MHT
1 stop5h 31m
American Airlines
Deal found 6/11![American Airlines logo]()
$527
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:25 am
MHT
- DSM
2 stops9h 08m
United Airlines
Mon 10/53:11 pm
DSM
- MHT
2 stops7h 45m
United Airlines
Deal found 6/15![United Airlines logo]()
$567
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:40 pm
MHT
- DSM
1 stop5h 20m
Southwest
Sun 11/296:10 pm
DSM
- MHT
1 stop4h 30m
Southwest
Deal found 6/12![Southwest logo]()
$597
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/142:37 pm
MHT
- DSM
2 stops7h 45m
United Airlines
Tue 7/216:00 am
DSM
- MHT
3 stops12h 02m
United Airlines
Deal found 6/14![United Airlines logo]()
$616
Last-minute flights from Manchester to Des MoinesDiscover last-minute flight deals from Manchester to Des Moines. Data last updated June 15, 2026 and is based on user searches.
Discover last-minute flight deals from Manchester to Des Moines. Data last updated June 15, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:35 am
MHT
- DSM
1 stop5h 59m
American Airlines
Tue 7/212:41 pm
DSM
- MHT
1 stop8h 07m
American Airlines
Deal found 6/14![American Airlines logo]()
$333
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/197:10 pm
MHT
- DSM
1 stop5h 40m
Southwest
Fri 7/245:10 am
DSM
- MHT
1 stop4h 40m
Southwest
Deal found 6/13![Southwest logo]()
$497
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:00 pm
MHT
- DSM
1 stop5h 35m
Southwest
Wed 7/295:20 am
DSM
- MHT
1 stop4h 30m
Southwest
Deal found 6/12![Southwest logo]()
$485
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:18 pm
MHT
- DSM
1 stop6h 43m
American Airlines
Tue 8/45:00 am
DSM
- MHT
1 stop5h 31m
American Airlines
Deal found 6/13![American Airlines logo]()
$380
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:00 pm
MHT
- DSM
1 stop5h 35m
Southwest
Mon 8/34:40 pm
DSM
- MHT
1 stop4h 20m
Southwest
Deal found 6/12![Southwest logo]()
$493
One-way flights from Manchester to Des MoinesSearch for one-way flight options from Manchester to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 15, 2026.
Search for one-way flight options from Manchester to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 15, 2026.
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:15 pm
MHT
- DSM
1 stop5h 35m
Southwest
Deal found 6/15![Southwest logo]()
$167
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:46 pm
MHT
- DSM
2 stops7h 42m
United Airlines
Deal found 6/14![United Airlines logo]()
$172
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:45 am
MHT
- DSM
1 stop5h 05m
Southwest
Deal found 6/14![Southwest logo]()
$188
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:25 pm
MHT
- DSM
1 stop4h 45m
Southwest
Deal found 6/14![Southwest logo]()
$214
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:05 am
MHT
- DSM
2 stops8h 45m
Southwest
Deal found 6/15![Southwest logo]()
$259
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/111:30 am
MHT
- DSM
2 stops11h 30m
Southwest
Deal found 6/15![Southwest logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/19:51 am
MHT
- DSM
3 stops54h 59m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$303
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:18 pm
MHT
- DSM
1 stop6h 43m
American Airlines
Deal found 6/15![American Airlines logo]()
$320
Find flight deals from Manchester to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $333 (American Airlines) |
One-way from | $167 (Southwest) |
Popular in | February |
Cheapest in | April |
Average price | $348 |
Cheapflights Fare Finder
Customize your flight search to find flights from Manchester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 15, 2026.
Use the filters below to find and compare flights from Manchester to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Tue 7/14
7:14 am-1:05 pm
1 stop6h 51m
Des Moines
Tue 7/21
1:35 pm-11:48 pm
2 stops9h 13m
$338
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Thu 7/30
6:18 pm-12:01 am
1 stop6h 43m
Des Moines
Tue 8/4
5:00 am-4:40 pm
2 stops10h 40m
$385
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Tue 9/1
2:46 pm-11:44 pm
2 stops9h 58m
Des Moines
Wed 9/2
6:00 am-7:00 pm
2 stops12h 00m
$433
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Tue 10/27
1:30 pm-11:01 pm
2 stops10h 31m
Des Moines
Wed 10/28
11:30 am-11:59 pm
2 stops11h 29m
$433
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Sun 7/19
7:10 pm-11:50 pm
1 stop5h 40m
Des Moines
Fri 7/24
4:40 pm-12:10 am
2 stops6h 30m
$502
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Thu 7/23
6:18 pm-12:01 am
1 stop6h 43m
Des Moines
Thu 7/30
5:00 am-11:31 am
1 stop5h 31m
$527
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Mon 7/27
12:30 pm-10:25 pm
2 stops10h 55m
Des Moines
Wed 7/29
5:20 am-3:20 pm
2 stops9h 00m
$558
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Fri 10/2
9:25 am-5:33 pm
2 stops9h 08m
Des Moines
Mon 10/5
3:11 pm-11:56 pm
2 stops7h 45m
$567
Quickest round-trip
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Fri 11/27
6:40 pm-11:00 pm
1 stop5h 20m
Des Moines
Sun 11/29
6:10 pm-11:40 pm
1 stop4h 30m
$597
ManchesterDes Moines
MHT - DSM
MHTDSM
Manchester
Tue 7/14
2:37 pm-9:22 pm
2 stops7h 45m
Des Moines
Tue 7/21
6:00 am-7:02 pm
3 stops12h 02m
$616
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Manchester to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to Des Moines in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Manchester, New Hampshire-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Manchester, New Hampshire-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Manchester, New Hampshire-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Manchester to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Manchester with our price prediction graph.
MHT-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated June 15, 2026.
Get a feel of what it's like to fly with American Airlines from Manchester to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Overall
7.1
Crew
7.9
Comfort
7.2
Food
6.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Boarding
7.5
Overall
7.1
Crew
7.9
Comfort
7.2
Food
6.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Related info for your journey
Find useful and relevant information for your journey from Manchester to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Ames
Johnston
Clive
Boone
West Des Moines
Ankeny
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Des Moines flight routes
Flights by cabin class
Other flight options
Other flights from Manchester
Popular flights
Alternative routes for Manchester to Des Moines
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 15, 2026.
Search flights from Manchester to Des Moines by cabin class
Find flights from Manchester to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Manchester and Des Moines flights
Browse other Manchester and Des Moines flight options. Last updated on June 15, 2026.
Other flights from Manchester
Browse through other flights departing from Manchester. Flights are based on user searches made on Cheapflights and were last updated on June 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Manchester to Des Moines
Discover the top airline that operate flights from Manchester to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$316 | Average$571 | FlexibilityNo cancel fee | On-time71% |