$148+ Cheap flights from Manchester, NH to Des Moines (MHT - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/26. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — DSM
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Manchester to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Manchester to Des Moines
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Cheapest flights from Manchester to Des MoinesExplore the most affordable flight options available from Manchester to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Manchester to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:22 pm -
2 stops7h 57m
Mon 11/231:58 pm -
2 stops8h 55m
Deal found 10/29![American Airlines logo]()
$305
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:00 pm -
1 stop5h 00m
Mon 11/234:25 pm -
1 stop4h 35m
Deal found 10/29![Southwest logo]()
$325
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:35 am -
1 stop4h 55m
Mon 12/215:10 am -
2 stops8h 05m
Deal found 10/25![Southwest logo]()
$330
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:26 pm -
2 stops7h 53m
Mon 11/231:58 pm -
2 stops8h 55m
Deal found 10/29![American Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:35 am -
1 stop4h 55m
Sun 12/205:10 am -
2 stops8h 05m
Deal found 10/25![Southwest logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:25 am -
2 stops9h 03m
Mon 11/231:27 pm -
2 stops9h 32m
Deal found 10/29![United Airlines logo]()
$456
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:22 pm -
2 stops7h 57m
Wed 11/251:58 pm -
2 stops8h 01m
Deal found 10/29![American Airlines logo]()
$484
Best flights from Manchester to Des MoinesDiscover carefully curated flight deals from Manchester to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Manchester to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:35 am -
1 stop4h 55m
Mon 12/215:10 am -
2 stops8h 05m
Deal found 10/25![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:25 am -
2 stops9h 03m
Wed 11/259:00 am -
2 stops13h 59m
Deal found 10/29![United Airlines logo]()
$456
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/85:52 pm -
1 stop6h 41m
Wed 1/272:39 pm -
2 stops8h 39m
Deal found 10/25![American Airlines logo]()
$497
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/85:10 pm -
1 stop5h 20m
Fri 1/293:00 pm -
1 stop4h 50m
Deal found 10/25![Southwest logo]()
$355
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/17:15 am -
1 stop5h 10m
Tue 1/53:30 pm -
1 stop4h 50m
Deal found 10/29![Southwest logo]()
$355
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:38 pm -
2 stops8h 17m
Wed 11/259:00 am -
2 stops13h 59m
Deal found 10/29![United Airlines logo]()
$485
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:40 pm -
1 stop5h 25m
Sun 12/205:10 am -
1 stop9h 45m
Deal found 10/25![Southwest logo]()
$410
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/187:00 pm -
1 stop5h 05m
Sat 4/245:35 pm -
2 stops13h 30m
Deal found 10/26![Southwest logo]()
$527
Last-minute flights from Manchester to Des MoinesDiscover last-minute flight deals from Manchester to Des Moines. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Manchester to Des Moines. Data last updated October 30, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:18 pm -
2 stops28h 53m
Mon 11/233:08 pm -
1 stop17h 37m
Deal found 10/29![Multiple Airlines logo]()
$528
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:15 pm -
2 stops12h 11m
Mon 11/231:58 pm -
2 stops8h 55m
Deal found 10/29![American Airlines logo]()
$542
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:25 am -
2 stops9h 03m
Mon 11/231:27 pm -
2 stops9h 32m
Deal found 10/29![United Airlines logo]()
$456
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:25 am -
2 stops9h 03m
Fri 11/206:45 pm -
2 stops28h 14m
Deal found 10/29![United Airlines logo]()
$552
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:22 pm -
2 stops7h 57m
Mon 11/231:58 pm -
2 stops8h 55m
Deal found 10/29![American Airlines logo]()
$305
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:00 pm -
1 stop5h 00m
Mon 11/234:25 pm -
1 stop4h 35m
Deal found 10/29![Southwest logo]()
$325
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:22 pm -
2 stops7h 57m
Wed 11/251:58 pm -
2 stops8h 01m
Deal found 10/29![American Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:26 pm -
2 stops7h 53m
Mon 11/231:58 pm -
2 stops8h 55m
Deal found 10/29![American Airlines logo]()
$355
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:38 pm -
2 stops8h 17m
Wed 11/259:00 am -
2 stops13h 59m
Deal found 10/29![United Airlines logo]()
$485
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:25 am -
2 stops10h 51m
Wed 11/259:00 am -
2 stops13h 59m
Deal found 10/29![United Airlines logo]()
$526
One-way flights from Manchester to Des MoinesSearch for one-way flight options from Manchester to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Manchester to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/261:20 pm -
1 stop4h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Southwest logo]()
$148
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
2 stops8h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![American Airlines logo]()
$198
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:32 pm -
2 stops7h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![American Airlines logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:24 pm -
3 stops26h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$346
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:40 pm -
1 stop5h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Southwest logo]()
$357
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/182:35 pm -
2 stops9h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![United Airlines logo]()
$469
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:24 pm -
3 stops32h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$481
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/292:35 pm -
2 stops7h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![United Airlines logo]()
$554
Find flight deals from Manchester to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $305 (American Airlines) |
One-way from | $148 (Southwest) |
Popular in | February |
Cheapest in | April |
Average price | $389 |
Cheapflights Fare Finder
Customize your flight search to find flights from Manchester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Manchester to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ManchesterDes Moines
MHT Manchester - DSM Des Moines
MHTDSM
Manchester
Thu 11/26
1:20 pm-5:15 pm
1 stop4h 55m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$148
ManchesterDes Moines
MHT Manchester - DSM Des Moines
MHTDSM
Manchester
Thu 12/17
7:35 am-11:30 am
1 stop4h 55m
Des Moines
Mon 12/21
5:10 am-2:15 pm
2 stops8h 05m
$330
ManchesterDes Moines
MHT Manchester - DSM Des Moines
MHTDSM
Manchester
Fri 1/8
5:10 pm-9:30 pm
1 stop5h 20m
Des Moines
Fri 1/29
3:00 pm-8:50 pm
1 stop4h 50m
$355
ManchesterDes Moines
MHT Manchester - DSM Des Moines
MHTDSM
Manchester
Fri 1/1
7:15 am-11:25 am
1 stop5h 10m
Des Moines
Tue 1/5
3:30 pm-9:20 pm
1 stop4h 50m
$355
ManchesterDes Moines
MHT Manchester - DSM Des Moines
MHTDSM
Manchester
Sun 11/15
6:40 pm-11:05 pm
1 stop5h 25m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$357
ManchesterDes Moines
MHT Manchester - DSM Des Moines
MHTDSM
Manchester
Thu 12/17
6:40 pm-11:05 pm
1 stop5h 25m
Des Moines
Sun 12/20
5:10 am-3:55 pm
1 stop9h 45m
$410
ManchesterDes Moines
MHT Manchester - DSM Des Moines
MHTDSM
Manchester
Thu 11/19
9:25 am-5:28 pm
2 stops9h 03m
Des Moines
Wed 11/25
9:00 am-11:59 pm
2 stops13h 59m
$456
ManchesterDes Moines
MHT Manchester - DSM Des Moines
MHTDSM
Manchester
Fri 12/18
2:35 pm-11:17 pm
2 stops9h 42m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$469
ManchesterDes Moines
MHT Manchester - DSM Des Moines
MHTDSM
Manchester
Sun 11/15
12:24 pm-7:35 pm
3 stops32h 11m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$481
ManchesterDes Moines
MHT Manchester - DSM Des Moines
MHTDSM
Manchester
Sun 11/22
2:38 pm-9:55 pm
2 stops8h 17m
Des Moines
Wed 11/25
9:00 am-11:59 pm
2 stops13h 59m
$485
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Manchester to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to Des Moines in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Manchester, New Hampshire-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Manchester, New Hampshire-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Manchester, New Hampshire-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Manchester to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Manchester with our price prediction graph.
MHT-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 30, 2026.
Get a feel of what it's like to fly with Southwest and American Airlines from Manchester to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.4
Overall
7.9
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.4
Overall
7.9
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.4
Overall
7.9
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Manchester to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
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Manchester and Des Moines flights
Browse other Manchester and Des Moines flight options. Last updated on October 30, 2026.
Other flights from Manchester
Browse through other flights departing from Manchester. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Manchester to Des Moines
Discover the top 2 airlines that operate flights from Manchester to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$355 | Average$589 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$379 | Average$512 | FlexibilityNo cancel fee | On-time71% |