$235+ Cheap flights from Portland, ME to Des Moines (PWM - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — DSM
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Des Moines
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Best
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One-way
Cheapest flights from Portland to Des MoinesExplore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:00 am -
1 stop9h 13m
Tue 12/16:13 am -
1 stop4h 44m
Deal found 10/27![Delta logo]()
$395
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:08 pm -
1 stop6h 51m
Tue 11/178:00 am -
1 stop5h 16m
Deal found 10/26![United Airlines logo]()
$426
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:08 pm -
1 stop6h 51m
Tue 12/19:30 am -
2 stops10h 12m
Deal found 10/27![United Airlines logo]()
$462
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:49 am -
2 stops9h 39m
Tue 11/243:24 pm -
1 stop5h 27m
Deal found 10/28![United Airlines logo]()
$467
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/224:50 pm -
1 stop4h 53m
Tue 11/245:30 am -
1 stop6h 31m
Deal found 10/26![Delta logo]()
$507
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:20 am -
2 stops17h 45m
Tue 11/176:00 am -
2 stops7h 45m
Deal found 10/26![Southwest logo]()
$538
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:23 pm -
1 stop9h 19m
Thu 11/126:05 am -
1 stop7h 11m
Deal found 10/26![United Airlines logo]()
$557
Best flights from Portland to Des MoinesDiscover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:00 am -
1 stop9h 13m
Tue 12/16:13 am -
1 stop4h 44m
Deal found 10/27![Delta logo]()
$395
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:10 am -
2 stops9h 41m
Sat 1/98:00 am -
1 stop5h 51m
Deal found 10/29![United Airlines logo]()
$454
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:20 am -
2 stops17h 45m
Tue 11/176:00 am -
2 stops7h 45m
Deal found 10/26![Southwest logo]()
$538
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/224:50 pm -
1 stop4h 53m
Tue 11/245:30 am -
1 stop6h 31m
Deal found 10/26![Delta logo]()
$507
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2410:50 am -
2 stops7h 38m
Tue 12/11:15 pm -
2 stops9h 09m
Deal found 10/27![United Airlines logo]()
$523
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:49 am -
2 stops9h 39m
Tue 11/246:05 am -
2 stops7h 22m
Deal found 10/26![United Airlines logo]()
$538
Last-minute flights from Portland to Des MoinesDiscover last-minute flight deals from Portland to Des Moines. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Des Moines. Data last updated October 30, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:23 pm -
1 stop9h 19m
Thu 11/126:05 am -
1 stop7h 11m
Deal found 10/26![United Airlines logo]()
$557
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:08 pm -
1 stop6h 51m
Tue 11/178:00 am -
1 stop5h 16m
Deal found 10/26![United Airlines logo]()
$426
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:20 am -
2 stops17h 45m
Tue 11/176:00 am -
2 stops7h 45m
Deal found 10/26![Southwest logo]()
$538
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:49 am -
2 stops9h 39m
Tue 11/243:24 pm -
1 stop5h 27m
Deal found 10/28![United Airlines logo]()
$467
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/224:50 pm -
1 stop4h 53m
Tue 11/245:30 am -
1 stop6h 31m
Deal found 10/26![Delta logo]()
$507
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:00 am -
1 stop9h 13m
Tue 12/16:13 am -
1 stop4h 44m
Deal found 10/27![Delta logo]()
$395
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:08 pm -
1 stop6h 51m
Tue 12/19:30 am -
2 stops10h 12m
Deal found 10/27![United Airlines logo]()
$462
One-way flights from Portland to Des MoinesSearch for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:09 pm -
2 stops39h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Multiple Airlines logo]()
$235
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:10 pm -
1 stop6h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:50 am -
2 stops9h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![United Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:53 pm -
3 stops43h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Multiple Airlines logo]()
$499
Find flight deals from Portland to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $395 (Delta) |
One-way from | $235 (Kiwi.com) |
Popular in | January |
Cheapest in | August |
Average price | $611 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Wed 11/11
5:09 pm-7:54 am
2 stops39h 45m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$235
Quickest round-trip
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Wed 11/11
4:10 pm-9:54 pm
1 stop6h 44m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$279
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Fri 11/13
3:23 pm-11:42 pm
1 stop9h 19m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$279
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Wed 11/11
10:50 am-7:16 pm
2 stops9h 26m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$284
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Fri 11/13
4:10 pm-12:26 am
2 stops9h 16m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$284
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Tue 11/24
6:00 am-2:13 pm
1 stop9h 13m
Des Moines
Tue 12/1
6:13 am-11:57 am
1 stop4h 44m
$395
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Wed 1/6
7:10 am-3:51 pm
2 stops9h 41m
Des Moines
Sat 1/9
8:00 am-2:51 pm
1 stop5h 51m
$454
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Fri 11/13
3:53 pm-10:08 am
3 stops43h 15m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$499
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Sun 11/22
4:50 pm-8:43 pm
1 stop4h 53m
Des Moines
Tue 11/24
5:30 am-1:01 pm
1 stop6h 31m
$507
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Tue 11/24
10:50 am-5:28 pm
2 stops7h 38m
Des Moines
Tue 12/1
1:15 pm-11:24 pm
2 stops9h 09m
$523
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Portland to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Des Moines in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland, Maine-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland, Maine-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland, Maine-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland, Maine-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Portland with our price prediction graph.
PWM-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Des Moines
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 30, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Portland to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Comfort
7.3
Boarding
7.7
Entertainment
7.1
Overall
7.3
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Crew
8.1
Comfort
7.3
Boarding
7.7
Entertainment
7.1
Overall
7.3
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Crew
8.1
Comfort
7.3
Boarding
7.7
Entertainment
7.1
Overall
7.3
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Portland to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
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Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
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Find flights from Portland to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Des Moines flights
Browse other Portland and Des Moines flight options. Last updated on October 30, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Portland to Des Moines
Discover the top 2 airlines that operate flights from Portland to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$309 | Average$498 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$390 | Average$539 | FlexibilityNo cancel fee | On-time69% |