$224+ Cheap flights from Des Moines to Portland, ME (DSM - PWM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PWM
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Portland with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Portland
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to PortlandExplore the most affordable flight options available from Des Moines to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Des Moines to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:26 am -
1 stop6h 38m
Sat 10/3110:07 am -
1 stop5h 24m
Deal found 9/15![American Airlines logo]()
$255
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:11 pm -
1 stop5h 35m
Wed 10/216:00 am -
1 stop7h 34m
Deal found 9/14![United Airlines logo]()
$320
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:26 am -
1 stop6h 38m
Sat 10/245:30 am -
1 stop8h 15m
Deal found 9/10![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:01 pm -
2 stops8h 58m
Wed 10/215:37 pm -
2 stops7h 37m
Deal found 9/14![American Airlines logo]()
$377
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:11 pm -
1 stop5h 43m
Fri 10/166:00 am -
1 stop5h 31m
Deal found 9/10![United Airlines logo]()
$398
Best flights from Des Moines to PortlandDiscover carefully curated flight deals from Des Moines to Portland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Des Moines to Portland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:26 am -
2 stops11h 10m
Sat 10/3110:07 am -
1 stop5h 24m
Deal found 9/15![American Airlines logo]()
$260
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/301:02 pm -
2 stops7h 46m
Wed 2/37:23 am -
2 stops8h 11m
Deal found 9/14![United Airlines logo]()
$355
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:11 pm -
1 stop5h 43m
Fri 10/166:00 am -
1 stop5h 31m
Deal found 9/10![United Airlines logo]()
$398
Last-minute flights from Des Moines to PortlandDiscover last-minute flight deals from Des Moines to Portland. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Portland. Data last updated September 15, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:11 pm -
1 stop5h 43m
Fri 10/166:00 am -
1 stop5h 31m
Deal found 9/10![United Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:11 pm -
1 stop5h 35m
Wed 10/216:00 am -
1 stop7h 34m
Deal found 9/14![United Airlines logo]()
$320
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:01 pm -
2 stops8h 58m
Wed 10/215:37 pm -
2 stops7h 37m
Deal found 9/14![American Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:26 am -
1 stop6h 38m
Sat 10/245:30 am -
1 stop8h 15m
Deal found 9/10![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:26 am -
1 stop6h 38m
Sat 10/3110:07 am -
1 stop5h 24m
Deal found 9/15![American Airlines logo]()
$255
One-way flights from Des Moines to PortlandSearch for one-way flight options from Des Moines to Portland. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Des Moines to Portland. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:01 pm -
2 stops8h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![American Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:10 am -
2 stops47h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$227
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:18 pm -
1 stop7h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Delta logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:43 am -
3 stops37h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$268
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:24 pm -
1 stop7h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$272
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:01 pm -
2 stops8h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![American Airlines logo]()
$294
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:05 am -
1 stop15h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![American Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am -
1 stop7h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$411
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:00 am -
3 stops14h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![United Airlines logo]()
$420
Find flight deals from Des Moines to Portland
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Portland (PWM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $320 (United Airlines) |
One-way from | $224 (American Airlines) |
Popular in | November |
Cheapest in | May |
Average price | $428 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Portland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Des Moines to Portland that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesPortland
DSM Des Moines - PWM Portland
DSMPWM
Des Moines
Fri 10/16
2:01 pm-11:59 pm
2 stops8h 58m
Portland
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$224
Quickest round-trip
Des MoinesPortland
DSM Des Moines - PWM Portland
DSMPWM
Des Moines
Fri 10/16
3:18 pm-11:35 pm
1 stop7h 17m
Portland
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$229
Des MoinesPortland
DSM Des Moines - PWM Portland
DSMPWM
Des Moines
Wed 10/28
9:26 am-9:36 pm
2 stops11h 10m
Portland
Sat 10/31
10:07 am-2:31 pm
1 stop5h 24m
$260
Des MoinesPortland
DSM Des Moines - PWM Portland
DSMPWM
Des Moines
Sat 1/30
1:02 pm-9:48 pm
2 stops7h 46m
Portland
Wed 2/3
7:23 am-2:34 pm
2 stops8h 11m
$355
Des MoinesPortland
DSM Des Moines - PWM Portland
DSMPWM
Des Moines
Thu 10/1
7:05 am-11:47 pm
1 stop15h 42m
Portland
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$375
Des MoinesPortland
DSM Des Moines - PWM Portland
DSMPWM
Des Moines
Tue 10/13
3:11 pm-9:54 pm
1 stop5h 43m
Portland
Fri 10/16
6:00 am-10:31 am
1 stop5h 31m
$398
Des MoinesPortland
DSM Des Moines - PWM Portland
DSMPWM
Des Moines
Thu 10/1
6:00 am-2:38 pm
1 stop7h 38m
Portland
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$411
Des MoinesPortland
DSM Des Moines - PWM Portland
DSMPWM
Des Moines
Fri 10/16
8:00 am-11:28 pm
3 stops14h 28m
Portland
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$420
Sorted by cheapest first
Compare providers for flights from Des Moines to Portland
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Portland in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Portland, Maine flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Portland, Maine flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Portland, Maine flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Portland, Maine flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Portland, Maine flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Portland
Have a flexible travel schedule? Discover the best time to fly to Portland from Des Moines with our price prediction graph.
DSM-PWM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Portland
Reviews of airlines servicing Portland
Get insights into the airlines that provide service to Portland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Portland. Reviews last updated September 15, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Des Moines to Portland by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Portland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Portland?
Book flights to Portland if you plan to visit one of these locationsNorth Conway
Lewiston
Brunswick
Conway
Browse thousands of different options on Cheapflights for your next trip
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Complete your trip
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Des Moines and Portland flights
Browse other Des Moines and Portland flight options. Last updated on September 15, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Portland
Explore flights to Portland departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Top 3 airlines flying from Des Moines to Portland
Discover the top 3 airlines that operate flights from Des Moines to Portland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$296 | Average$462 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$356 | Average$458 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$384 | Average$500 | FlexibilityNo cancel fee | On-time71% |