HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Portland

$369+ Cheap flights from Des Moines to Portland, ME (DSM - PWM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PWM
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Portland with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Des Moines to Portland are usually found in September or February, booked 45 days in advance, depart on a Tuesday or Monday and return on a Wednesday

Cheap flight deals from Des Moines to Portland

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Portland (PWM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$416
(United Airlines)

One-way from

$369
(American Airlines)

Popular in

November

Cheapest in

September

Average price

$739
Provider with most accurate pricing for Des Moines-Portland flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Portland flights.
Search Deals
From Des Moines to Portland
Search Deals
One-way flight from Des Moines to Portland
Search Deals
Highest demand for flights based on searches. 26% potential increase in price ($159 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Des Moines to Portland

Cheapest flights from Des Moines to Portland
Explore the most affordable flight options available from Des Moines to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/28:00 amDSM - PWM
1 stop5h 22mUnited Airlines
Wed 12/34:25 pmPWM - DSM
1 stop6h 12mUnited Airlines
Deal found 11/6$416
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:40 amDSM - PWM
2 stops26h 56mMultiple Airlines
Tue 11/257:35 pmPWM - DSM
1 stop26h 34mMultiple Airlines
Deal found 11/6$459
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:21 amDSM - PWM
1 stop4h 46mDelta
Tue 11/256:00 amPWM - DSM
1 stop8h 32mDelta
Deal found 11/6$487
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/218:02 amDSM - PWM
1 stop5h 10mUnited Airlines
Tue 11/255:00 pmPWM - DSM
1 stop5h 32mUnited Airlines
Deal found 11/6$567
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2311:35 amDSM - PWM
1 stop8h 54mUnited Airlines
Fri 12/269:30 amPWM - DSM
1 stop6h 03mUnited Airlines
Deal found 11/6$587
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:30 amDSM - PWM
2 stops17h 35mSouthwest
Fri 12/265:30 amPWM - DSM
2 stops19h 35mSouthwest
Deal found 11/6$594

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Portland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Des Moines to Portland that are best for you.

Fly from

Des Moines

Fly to

Portland

Route

Depart

Return

Price

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Tue 12/2

8:00 am-2:22 pm

1 stop5h 22m

Portland

Wed 12/3

4:25 pm-9:37 pm

1 stop6h 12m

$416

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Fri 11/21

6:40 am-10:36 am

2 stops26h 56m

Portland

Tue 11/25

7:35 pm-9:09 pm

1 stop26h 34m

$459

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Fri 11/21

10:21 am-4:07 pm

1 stop4h 46m

Portland

Tue 11/25

6:00 am-1:32 pm

1 stop8h 32m

$487

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Fri 11/21

8:02 am-2:12 pm

1 stop5h 10m

Portland

Tue 11/25

5:00 pm-9:32 pm

1 stop5h 32m

$567

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Tue 12/23

11:35 am-9:29 pm

1 stop8h 54m

Portland

Fri 12/26

9:30 am-2:33 pm

1 stop6h 03m

$587

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Tue 12/23

5:30 am-12:05 am

2 stops17h 35m

Portland

Fri 12/26

5:30 am-12:05 am

2 stops19h 35m

$594

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Tue 11/11

6:00 am-11:46 am

1 stop4h 46m

$369

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Tue 11/11

11:28 am-11:19 pm

2 stops10h 51m

$374

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Fri 11/14

6:00 am-11:46 am

1 stop4h 46m

$442

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Tue 11/11

8:02 am-2:12 pm

1 stop5h 10m

$455

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Compare providers for flights from Des Moines to Portland

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Portland in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Portland, Maine flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Portland, Maine flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Portland, Maine flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Portland, Maine flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Portland, Maine flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Portland

Have a flexible travel schedule? Discover the best time to fly to Portland from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Portland

How far ahead should I book a flight from Des Moines to Portland, Maine?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Portland. Price data was last updated on October 31, 2025.

To ensure you get the cheapest price possible for a flight from Des Moines to Portland, Maine, you should look to book at least 43 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Des Moines to Portland, Maine?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Portland, Maine (average of $96). Flying from Des Moines to Portland, Maine in February is currently the most expensive (average of $351). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Portland, Maine?

Reviews of airlines servicing Portland

Get insights into the airlines that provide service to Portland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Portland. Reviews last updated November 6, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Portland by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,001 reviews

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,001 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,007 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Portland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Portland, Maine?

    For as low as $487, United Airlines can have you in Portland, Maine from Des Moines in 4h 46m. Des Moines and Portland, Maine are separated by a distance of 1192 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Des Moines to Portland, Maine round-trip?

    According to our current data, Delta ($276), American Airlines ($296), and United Airlines ($321) offers the cheapest pricing from Des Moines to Portland, Maine. These flights start at 38% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Des Moines to Portland, Maine one-way?

    $369 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $374 and $455, respectively.

  • Can I find deals for flights from Des Moines to Portland that include hotel bookings?

    Yes. In addition to deals on Des Moines to Portland flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Portland?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Portland.

  • Can I find deals for business class flights from Des Moines to Portland?

    Yes. Cheapflights offers flight deals from Des Moines to Portland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Portland, Maine?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Portland, Maine (average of $96). Flying from Des Moines to Portland, Maine in February is currently the most expensive (average of $351). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Portland?

Book flights to Portland if you plan to visit one of these locations
North Conway
Brunswick
Auburn
Conway

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Des Moines to Portland

Discover the top 3 airlines that operate flights from Des Moines to Portland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$276Average$481FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$296Average$422FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$321Average$487FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.