$172+ Cheap flights from Des Moines to Portland, ME (DSM - PWM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/6. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PWM
Aug 24 — Aug 311
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Portland with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Portland
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Best
Last-minute
One-way
Cheapest flights from Des Moines to PortlandExplore the most affordable flight options available from Des Moines to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 25, 2026.
Explore the most affordable flight options available from Des Moines to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 25, 2026.
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:09 pm
DSM
- PWM
1 stop7h 12m
American Airlines
Sat 9/56:46 am
PWM
- DSM
1 stop7h 39m
American Airlines
Deal found 7/22![American Airlines logo]()
$333
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:28 am
DSM
- PWM
2 stops11h 02m
Delta
Sat 9/56:10 am
PWM
- DSM
1 stop6h 31m
Delta
Deal found 7/23![Delta logo]()
$338
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:11 pm
DSM
- PWM
1 stop6h 02m
Delta
Sun 9/66:05 am
PWM
- DSM
1 stop6h 16m
Delta
Deal found 7/22![Delta logo]()
$343
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:59 am
DSM
- PWM
2 stops9h 32m
Delta
Sat 9/126:30 am
PWM
- DSM
1 stop6h 02m
Delta
Deal found 7/25![Delta logo]()
$354
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
DSM
- PWM
2 stops9h 49m
Delta
Wed 9/166:30 am
PWM
- DSM
2 stops8h 19m
Delta
Deal found 7/24![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:20 am
DSM
- PWM
1 stop4h 33m
Delta
Mon 11/233:00 pm
PWM
- DSM
1 stop6h 00m
Delta
Deal found 7/22![Delta logo]()
$362
Best flights from Des Moines to PortlandDiscover carefully curated flight deals from Des Moines to Portland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 25, 2026.
Discover carefully curated flight deals from Des Moines to Portland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 25, 2026.
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:11 pm
DSM
- PWM
1 stop6h 18m
Delta
Wed 9/166:00 am
PWM
- DSM
1 stop8h 49m
Delta
Deal found 7/23![Delta logo]()
$333
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/263:11 pm
DSM
- PWM
1 stop5h 35m
United Airlines
Tue 9/295:15 am
PWM
- DSM
2 stops10h 00m
United Airlines
Deal found 7/24![United Airlines logo]()
$344
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:20 pm
DSM
- PWM
1 stop5h 03m
United Airlines
Tue 9/19:49 am
PWM
- DSM
2 stops8h 29m
United Airlines
Deal found 7/25![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:28 am
DSM
- PWM
2 stops11h 02m
Delta
Sun 9/66:05 am
PWM
- DSM
1 stop6h 16m
Delta
Deal found 7/22![Delta logo]()
$348
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am
DSM
- PWM
1 stop7h 34m
United Airlines
Sun 9/136:00 am
PWM
- DSM
1 stop5h 31m
United Airlines
Deal found 7/25![United Airlines logo]()
$388
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:59 am
DSM
- PWM
2 stops9h 32m
Delta
Mon 9/146:00 am
PWM
- DSM
1 stop8h 49m
Delta
Deal found 7/25![Delta logo]()
$408
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/121:24 pm
DSM
- PWM
1 stop7h 22m
United Airlines
Fri 10/165:08 pm
PWM
- DSM
1 stop7h 27m
United Airlines
Deal found 7/25![United Airlines logo]()
$415
Last-minute flights from Des Moines to PortlandDiscover last-minute flight deals from Des Moines to Portland. Data last updated July 25, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Portland. Data last updated July 25, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:40 am
DSM
- PWM
1 stop7h 41m
American Airlines
Mon 8/247:28 am
PWM
- DSM
1 stop6h 06m
American Airlines
Deal found 7/23![American Airlines logo]()
$395
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:40 am
DSM
- PWM
1 stop7h 41m
American Airlines
Sun 8/307:33 am
PWM
- DSM
1 stop6h 01m
American Airlines
Deal found 7/24![American Airlines logo]()
$388
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:09 pm
DSM
- PWM
1 stop7h 12m
American Airlines
Sat 9/56:46 am
PWM
- DSM
1 stop7h 39m
American Airlines
Deal found 7/22![American Airlines logo]()
$333
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:28 am
DSM
- PWM
2 stops11h 02m
Delta
Sat 9/56:10 am
PWM
- DSM
1 stop6h 31m
Delta
Deal found 7/23![Delta logo]()
$338
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:11 pm
DSM
- PWM
1 stop6h 02m
Delta
Sun 9/66:05 am
PWM
- DSM
1 stop6h 16m
Delta
Deal found 7/22![Delta logo]()
$343
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:11 pm
DSM
- PWM
1 stop6h 02m
Delta
Tue 9/86:00 am
PWM
- DSM
1 stop5h 46m
Delta
Deal found 7/22![Delta logo]()
$396
One-way flights from Des Moines to PortlandSearch for one-way flight options from Des Moines to Portland. Find affordable one-way fares based on user searches. Data last updated July 25, 2026.
Search for one-way flight options from Des Moines to Portland. Find affordable one-way fares based on user searches. Data last updated July 25, 2026.
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:40 am
DSM
- PWM
1 stop6h 27m
Delta
Deal found 7/22![Delta logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am
DSM
- PWM
3 stops56h 44m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$193
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:10 am
DSM
- PWM
2 stops9h 23m
American Airlines
Deal found 7/22![American Airlines logo]()
$196
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:00 am
DSM
- PWM
3 stops14h 32m
United Airlines
Deal found 7/21![United Airlines logo]()
$222
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/43:11 pm
DSM
- PWM
1 stop5h 35m
United Airlines
Deal found 7/24![United Airlines logo]()
$268
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/710:59 am
DSM
- PWM
2 stops11h 31m
Delta
Deal found 7/21![Delta logo]()
$310
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/71:08 pm
DSM
- PWM
1 stop7h 52m
American Airlines
Deal found 7/24![American Airlines logo]()
$312
Find flight deals from Des Moines to Portland
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Portland (PWM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $333 (American Airlines) |
One-way from | $167 (United Airlines) |
Popular in | November |
Cheapest in | September |
Average price | $516 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Portland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2026.
Use the filters below to find and compare flights from Des Moines to Portland that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesPortland
DSM - PWM
DSMPWM
Des Moines
Wed 9/9
4:11 pm-11:29 pm
1 stop6h 18m
Portland
Wed 9/16
6:00 am-1:49 pm
1 stop8h 49m
$333
Des MoinesPortland
DSM - PWM
DSMPWM
Des Moines
Sat 9/26
3:11 pm-9:46 pm
1 stop5h 35m
Portland
Tue 9/29
5:15 am-2:15 pm
2 stops10h 00m
$344
Des MoinesPortland
DSM - PWM
DSMPWM
Des Moines
Thu 8/27
3:20 pm-9:23 pm
1 stop5h 03m
Portland
Tue 9/1
9:49 am-5:18 pm
2 stops8h 29m
$344
Des MoinesPortland
DSM - PWM
DSMPWM
Des Moines
Mon 8/31
11:28 am-11:30 pm
2 stops11h 02m
Portland
Sun 9/6
6:05 am-11:21 am
1 stop6h 16m
$348
Quickest round-trip
Des MoinesPortland
DSM - PWM
DSMPWM
Des Moines
Sat 9/5
6:00 am-2:34 pm
1 stop7h 34m
Portland
Sun 9/13
6:00 am-10:31 am
1 stop5h 31m
$388
Des MoinesPortland
DSM - PWM
DSMPWM
Des Moines
Sat 9/5
10:59 am-9:31 pm
2 stops9h 32m
Portland
Mon 9/14
6:00 am-1:49 pm
1 stop8h 49m
$408
Des MoinesPortland
DSM - PWM
DSMPWM
Des Moines
Mon 10/12
1:24 pm-9:46 pm
1 stop7h 22m
Portland
Fri 10/16
5:08 pm-11:35 pm
1 stop7h 27m
$415
Cheapest one-way
Des MoinesPortland
DSM - PWM
DSMPWM
Des Moines
Sun 9/6
5:40 am-1:07 pm
1 stop6h 27m
$172
Des MoinesPortland
DSM - PWM
DSMPWM
Des Moines
Sun 9/6
6:10 am-4:33 pm
2 stops9h 23m
$201
Des MoinesPortland
DSM - PWM
DSMPWM
Des Moines
Sun 9/6
8:00 am-11:32 pm
3 stops14h 32m
$227
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Portland
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Portland in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Portland, Maine flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Portland, Maine flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Portland, Maine flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Portland, Maine flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Portland, Maine flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Portland
Have a flexible travel schedule? Discover the best time to fly to Portland from Des Moines with our price prediction graph.
DSM-PWM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Portland
Reviews of airlines servicing Portland
Get insights into the airlines that provide service to Portland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Portland. Reviews last updated July 25, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Des Moines to Portland by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Portland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Portland?
Book flights to Portland if you plan to visit one of these locationsNorth Conway
Lewiston
Brunswick
Conway
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Des Moines and Portland flights
Browse other Des Moines and Portland flight options. Last updated on July 25, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on July 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Portland
Explore flights to Portland departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 25, 2026.
Top 3 airlines flying from Des Moines to Portland
Discover the top 3 airlines that operate flights from Des Moines to Portland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$271 | Average$478 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$284 | Average$462 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$326 | Average$487 | FlexibilityNo cancel fee | On-time69% |