$253+ Cheap flights from Des Moines to Manchester, NH (DSM - MHT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MHT
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Manchester with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
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One-way
Cheapest flights from Des Moines to ManchesterExplore the most affordable flight options available from Des Moines to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Des Moines to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:00 pm -
1 stop5h 10m
Tue 10/275:50 pm -
1 stop5h 10m
Deal found 9/16![Southwest logo]()
$281
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:01 pm -
2 stops8h 35m
Tue 10/2712:55 pm -
1 stop7h 59m
Deal found 9/16![American Airlines logo]()
$286
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/294:30 pm -
1 stop4h 25m
Tue 11/37:15 am -
1 stop5h 10m
Deal found 9/14![Southwest logo]()
$301
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:30 pm -
1 stop4h 25m
Tue 10/205:50 pm -
1 stop5h 10m
Deal found 9/15![Southwest logo]()
$320
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:05 am -
1 stop7h 29m
Wed 10/215:05 pm -
1 stop8h 09m
Deal found 9/16![American Airlines logo]()
$357
Best flights from Des Moines to ManchesterDiscover carefully curated flight deals from Des Moines to Manchester that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Des Moines to Manchester that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:00 pm -
1 stop5h 10m
Tue 10/275:50 pm -
1 stop5h 10m
Deal found 9/14![Southwest logo]()
$282
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:10 am -
1 stop4h 40m
Tue 11/35:35 am -
2 stops6h 50m
Deal found 9/14![Southwest logo]()
$306
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:30 pm -
1 stop4h 25m
Tue 10/275:50 pm -
1 stop5h 10m
Deal found 9/14![Southwest logo]()
$359
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:25 am -
1 stop10h 15m
Fri 11/137:35 am -
1 stop4h 55m
Deal found 9/15![Southwest logo]()
$404
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:30 pm -
1 stop4h 25m
Mon 10/266:55 pm -
1 stop5h 20m
Deal found 9/14![Southwest logo]()
$437
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:10 am -
2 stops8h 50m
Wed 10/213:50 pm -
2 stops7h 10m
Deal found 9/16![Southwest logo]()
$476
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:35 am -
2 stops8h 40m
Mon 10/261:40 pm -
2 stops10h 35m
Deal found 9/16![Southwest logo]()
$497
Last-minute flights from Des Moines to ManchesterDiscover last-minute flight deals from Des Moines to Manchester. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Manchester. Data last updated September 17, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:05 am -
1 stop7h 29m
Wed 10/215:05 pm -
1 stop8h 09m
Deal found 9/16![American Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:30 pm -
1 stop4h 25m
Tue 10/205:50 pm -
1 stop5h 10m
Deal found 9/15![Southwest logo]()
$320
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:00 pm -
1 stop5h 10m
Tue 10/275:50 pm -
1 stop5h 10m
Deal found 9/16![Southwest logo]()
$281
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:01 pm -
2 stops8h 35m
Wed 10/285:05 pm -
1 stop8h 09m
Deal found 9/16![American Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:01 pm -
2 stops9h 22m
Tue 10/275:24 pm -
2 stops7h 50m
Deal found 9/16![American Airlines logo]()
$291
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/294:30 pm -
1 stop4h 25m
Tue 11/37:15 am -
1 stop5h 10m
Deal found 9/14![Southwest logo]()
$301
One-way flights from Des Moines to ManchesterSearch for one-way flight options from Des Moines to Manchester. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Des Moines to Manchester. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/185:30 am -
2 stops8h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$253
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:57 pm -
1 stop5h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![American Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:30 am -
2 stops8h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Southwest logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:54 pm -
3 stops21h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$427
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:24 pm -
2 stops7h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$459
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:00 am -
3 stops10h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![United Airlines logo]()
$554
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/298:00 am -
2 stops14h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![United Airlines logo]()
$1,013
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:23 am -
3 stops11h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$1,028
Find flight deals from Des Moines to Manchester
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Manchester (MHT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $281 (Southwest) |
One-way from | $253 (Southwest) |
Popular in | July |
Cheapest in | January |
Average price | $456 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Des Moines to Manchester that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Sun 10/18
5:30 am-2:55 pm
2 stops8h 25m
Manchester
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$253
Quickest round-trip
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Sat 9/26
5:57 pm-12:22 am
1 stop5h 25m
Manchester
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$269
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Sat 9/26
5:30 am-2:55 pm
2 stops8h 25m
Manchester
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$274
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Wed 10/21
3:00 pm-9:10 pm
1 stop5h 10m
Manchester
Tue 10/27
5:50 pm-10:00 pm
1 stop5h 10m
$282
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Thu 10/29
5:10 am-10:50 am
1 stop4h 40m
Manchester
Tue 11/3
5:35 am-11:25 am
2 stops6h 50m
$306
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Thu 10/22
4:30 pm-9:55 pm
1 stop4h 25m
Manchester
Tue 10/27
5:50 pm-10:00 pm
1 stop5h 10m
$359
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Sun 11/1
5:25 am-4:40 pm
1 stop10h 15m
Manchester
Fri 11/13
7:35 am-11:30 am
1 stop4h 55m
$404
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Sun 10/18
3:54 pm-2:34 pm
3 stops21h 40m
Manchester
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$427
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Thu 10/22
4:30 pm-9:55 pm
1 stop4h 25m
Manchester
Mon 10/26
6:55 pm-11:15 pm
1 stop5h 20m
$437
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Fri 10/30
3:24 pm-11:59 pm
2 stops7h 35m
Manchester
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$459
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Manchester
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Manchester in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Manchester, New Hampshire flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Manchester, New Hampshire flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Manchester, New Hampshire flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Manchester, New Hampshire flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Manchester, New Hampshire flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Manchester
Have a flexible travel schedule? Discover the best time to fly to Manchester from Des Moines with our price prediction graph.
DSM-MHT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Manchester
Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated September 17, 2026.
See what other customers who have flown with Southwest and American Airlines from Des Moines to Manchester have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Crew
8.6
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Crew
8.6
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Manchester?
Book flights to Manchester if you plan to visit one of these locationsKeene
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Other flights to Manchester
Explore flights to Manchester departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 17, 2026.
Des Moines and Manchester flights
Browse other Des Moines and Manchester flight options. Last updated on September 17, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Manchester
Discover the top 2 airlines that operate flights from Des Moines to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$307 | Average$359 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$379 | Average$486 | FlexibilityNo cancel fee | On-time63% |