$222+ Cheap flights from Des Moines to Manchester, NH (DSM - MHT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/20. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MHT
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Manchester with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Manchester
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Best
Last-minute
One-way
Cheapest flights from Des Moines to ManchesterExplore the most affordable flight options available from Des Moines to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Des Moines to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:25 am -
2 stops11h 23m
Sat 11/215:22 pm -
2 stops7h 57m
Deal found 10/26![American Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/223:26 pm -
2 stops7h 32m
Tue 12/296:00 am -
2 stops9h 56m
Deal found 10/26![American Airlines logo]()
$468
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:30 pm -
1 stop4h 50m
Sun 11/226:40 pm -
1 stop5h 25m
Deal found 10/29![Southwest logo]()
$476
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:25 pm -
1 stop4h 40m
Sat 11/217:00 pm -
1 stop5h 00m
Deal found 10/29![Southwest logo]()
$479
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:30 pm -
1 stop4h 50m
Sat 11/143:40 pm -
1 stop5h 05m
Deal found 10/26![Southwest logo]()
$557
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:23 am -
2 stops8h 29m
Sat 11/146:00 am -
2 stops8h 28m
Deal found 10/26![American Airlines logo]()
$567
Best flights from Des Moines to ManchesterDiscover carefully curated flight deals from Des Moines to Manchester that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Des Moines to Manchester that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:25 pm -
1 stop4h 40m
Sat 11/217:00 pm -
1 stop5h 00m
Deal found 10/29![Southwest logo]()
$479
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:47 am -
1 stop17h 11m
Tue 12/296:00 am -
2 stops9h 56m
Deal found 10/29![American Airlines logo]()
$653
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:24 pm -
2 stops7h 35m
Sat 11/149:25 am -
2 stops9h 08m
Deal found 10/26![United Airlines logo]()
$677
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:42 pm -
2 stops18h 18m
Sat 1/22:35 pm -
2 stops9h 42m
Deal found 10/26![United Airlines logo]()
$899
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:00 am -
3 stops14h 59m
Sat 11/219:25 am -
2 stops13h 30m
Deal found 10/29![United Airlines logo]()
$948
Last-minute flights from Des Moines to ManchesterDiscover last-minute flight deals from Des Moines to Manchester. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Manchester. Data last updated October 30, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:30 pm -
1 stop4h 50m
Sat 11/143:40 pm -
1 stop5h 05m
Deal found 10/26![Southwest logo]()
$557
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:23 am -
2 stops8h 29m
Sat 11/146:00 am -
2 stops8h 28m
Deal found 10/26![American Airlines logo]()
$567
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:24 pm -
2 stops7h 35m
Sat 11/149:25 am -
2 stops9h 08m
Deal found 10/26![United Airlines logo]()
$677
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:25 am -
2 stops11h 23m
Sat 11/215:22 pm -
2 stops7h 57m
Deal found 10/26![American Airlines logo]()
$467
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:25 pm -
1 stop4h 40m
Sat 11/217:00 pm -
1 stop5h 00m
Deal found 10/29![Southwest logo]()
$479
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:30 pm -
1 stop4h 50m
Sun 11/226:40 pm -
1 stop5h 25m
Deal found 10/29![Southwest logo]()
$476
One-way flights from Des Moines to ManchesterSearch for one-way flight options from Des Moines to Manchester. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Des Moines to Manchester. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/205:10 am -
2 stops8h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Southwest logo]()
$222
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop5h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![American Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/63:11 pm -
1 stop17h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/611:22 am -
2 stops11h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![United Airlines logo]()
$412
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/54:15 pm -
2 stops42h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$448
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:25 am -
1 stop10h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Southwest logo]()
$476
Find flight deals from Des Moines to Manchester
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Manchester (MHT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $467 (American Airlines) |
One-way from | $222 (Southwest) |
Popular in | September |
Cheapest in | January |
Average price | $429 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Des Moines to Manchester that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Sun 12/20
5:10 am-3:55 pm
1 stop9h 45m
Manchester
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$263
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Tue 11/10
6:00 am-12:34 pm
1 stop5h 34m
Manchester
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$279
Quickest round-trip
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Wed 11/11
3:30 pm-9:20 pm
1 stop4h 50m
Manchester
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$279
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Wed 11/11
1:27 pm-11:59 pm
2 stops9h 32m
Manchester
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$284
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Fri 11/6
11:22 am-11:59 pm
2 stops11h 37m
Manchester
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$412
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Thu 11/5
4:15 pm-11:38 am
2 stops42h 23m
Manchester
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$448
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Thu 11/5
5:25 am-4:40 pm
1 stop10h 15m
Manchester
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$476
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Sun 11/15
4:25 pm-10:05 pm
1 stop4h 40m
Manchester
Sat 11/21
7:00 pm-11:00 pm
1 stop5h 00m
$479
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Fri 11/6
6:40 am-8:30 pm
2 stops12h 50m
Manchester
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$497
Des MoinesManchester
DSM Des Moines - MHT Manchester
DSMMHT
Des Moines
Tue 11/10
11:22 am-11:59 pm
3 stops11h 37m
Manchester
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$502
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Manchester
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Manchester in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Manchester, New Hampshire flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Manchester, New Hampshire flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Manchester, New Hampshire flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Manchester, New Hampshire flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Manchester, New Hampshire flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Manchester
Have a flexible travel schedule? Discover the best time to fly to Manchester from Des Moines with our price prediction graph.
DSM-MHT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Manchester
Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated October 30, 2026.
See what other customers who have flown with Southwest and American Airlines from Des Moines to Manchester have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Boarding
8.1
Entertainment
7.4
Food
7.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Boarding
8.1
Entertainment
7.4
Food
7.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Boarding
8.1
Entertainment
7.4
Food
7.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Manchester?
Book flights to Manchester if you plan to visit one of these locationsKeene
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Other flights to Manchester
Explore flights to Manchester departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Des Moines and Manchester flights
Browse other Des Moines and Manchester flight options. Last updated on October 30, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Manchester
Discover the top 2 airlines that operate flights from Des Moines to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$307 | Average$382 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$379 | Average$486 | FlexibilityNo cancel fee | On-time63% |