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Des Moines

$197+ Cheap flights from Gulfport to Des Moines (GPT - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
GPT — DSM
May 24 — May 311
Sun 5/24
Sun 5/31
1 adult, Economy
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Cheap flight deals from Gulfport to Des Moines

Cheapest flights from Gulfport to Des Moines
Explore the most affordable flight options available from Gulfport to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.

This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:00 am
GPT
-
DSM
1 stop6h 26m
American Airlines
Sun 5/105:00 am
DSM
-
GPT
1 stop5h 33m
American Airlines
Deal found 4/19$334
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:03 pm
GPT
-
DSM
1 stop6h 56m
American Airlines
Tue 5/1212:06 pm
DSM
-
GPT
2 stops11h 20m
American Airlines
Deal found 4/21$339
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:50 pm
GPT
-
DSM
1 stop13h 43m
Multiple Airlines
Sun 5/107:45 am
DSM
-
GPT
2 stops23h 56m
Multiple Airlines
Deal found 4/19$410
This deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:02 pm
GPT
-
DSM
1 stop4h 30m
Delta
Sat 6/64:00 pm
DSM
-
GPT
1 stop5h 51m
Delta
Deal found 4/23$429
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:00 am
GPT
-
DSM
1 stop6h 10m
American Airlines
Mon 4/275:00 am
DSM
-
GPT
1 stop5h 33m
American Airlines
Deal found 4/21$446
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:32 am
GPT
-
DSM
1 stop4h 36m
Delta
Wed 5/2711:57 am
DSM
-
GPT
1 stop5h 17m
Delta
Deal found 4/23$494
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:00 pm
GPT
-
DSM
2 stops9h 55m
United Airlines
Wed 9/26:00 am
DSM
-
GPT
2 stops10h 02m
United Airlines
Deal found 4/19$499

Find flight deals from Gulfport to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Gulfport (GPT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$334
(American Airlines)

One-way from

$197
(Kiwi.com)
Provider with most accurate pricing for Gulfport Biloxi Regional-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Des Moines flights.
Search Deals
From Gulfport Biloxi Regional to Des Moines
Search Deals
One-way flight from Gulfport Biloxi Regional to Des Moines
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Gulfport to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Gulfport to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GulfportDes Moines

GPT - DSM

GPTDSM

Gulfport Biloxi Regional

Fri 5/8

5:03 pm-11:59 pm

1 stop6h 56m

Des Moines

Tue 5/12

5:00 am-10:33 am

1 stop5h 33m

$334

GulfportDes Moines

GPT - DSM

GPTDSM

Gulfport Biloxi Regional

Thu 5/7

12:42 pm-11:49 pm

2 stops11h 07m

Des Moines

Sun 5/10

5:00 am-10:33 am

1 stop5h 33m

$394

GulfportDes Moines

GPT - DSM

GPTDSM

Gulfport Biloxi Regional

Fri 6/5

6:02 pm-10:32 pm

1 stop4h 30m

Des Moines

Sat 6/6

4:00 pm-9:51 pm

1 stop5h 51m

$429
Quickest round-trip

GulfportDes Moines

GPT - DSM

GPTDSM

Gulfport Biloxi Regional

Mon 5/25

6:32 am-11:08 am

1 stop4h 36m

Des Moines

Wed 5/27

11:57 am-5:14 pm

1 stop5h 17m

$494

GulfportDes Moines

GPT - DSM

GPTDSM

Gulfport Biloxi Regional

Sat 8/29

2:00 pm-11:55 pm

2 stops9h 55m

Des Moines

Wed 9/2

5:00 am-4:02 pm

2 stops11h 02m

$499
Cheapest one-way
Quickest one-way

GulfportDes Moines

GPT - DSM

GPTDSM

Gulfport Biloxi Regional

Thu 5/28

6:38 pm-12:17 am

1 stop5h 39m

$211

GulfportDes Moines

GPT - DSM

GPTDSM

Gulfport Biloxi Regional

Thu 5/28

7:50 pm-1:35 pm

3 stops41h 45m

$290

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/24

Sorted by cheapest first

Compare providers for flights from Gulfport to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Gulfport to Des Moines in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Gulfport-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Gulfport-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Gulfport-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Gulfport-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gulfport-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Gulfport to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Gulfport with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated April 24, 2026.
Get a feel of what it's like to fly with Delta from Gulfport to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,450 reviews

Comfort

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,450 reviews
Delta
7.9
Good
8,450 reviews

Comfort

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Gulfport to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Gulfport to Des Moines?

    There are many flights that can get you from Gulfport to Des Moines in 4h 30m. Fly via American Airlines or Delta to get the fastest option. Airlines will cover a distance of 810 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Gulfport to Des Moines round-trip?

    Our cheapest airline available from Gulfport to Des Moines is Delta. Our recent data shows that you can find tickets from as low as $124 on this airline.

  • Can I find deals for flights from Gulfport to Des Moines that include hotel bookings?

    Yes. In addition to deals on Gulfport to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gulfport to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gulfport to Des Moines.

  • Can I find deals for business class flights from Gulfport to Des Moines?

    Yes. Cheapflights offers flight deals from Gulfport to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny

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Top airline flying from Gulfport to Des Moines

Discover the top airline that operate flights from Gulfport to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$124Average$268FlexibilityNo cancel feeOn-timeN/A

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