$229+ Cheap flights from Tucson to Des Moines (TUS - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
TUS — DSM
Nov 20 — Nov 271
Round-trip
1 adult, Economy
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Find cheap flights from Tucson to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Tucson to Des Moines
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Cheapest flights from Tucson to Des MoinesExplore the most affordable flight options available from Tucson to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 21, 2026.
Explore the most affordable flight options available from Tucson to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 21, 2026.
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/178:45 am -
2 stops8h 50m
Mon 1/1112:15 pm -
1 stop6h 20m
Deal found 10/20![Southwest logo]()
$272
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/305:55 pm -
1 stop4h 49m
Tue 1/55:00 am -
1 stop5h 17m
Deal found 10/19![American Airlines logo]()
$303
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/265:29 pm -
1 stop5h 30m
Wed 1/69:00 am -
1 stop7h 42m
Deal found 10/20![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3011:15 am -
1 stop6h 20m
Tue 1/56:30 pm -
1 stop4h 55m
Deal found 10/18![Southwest logo]()
$362
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:00 am -
2 stops6h 15m
Wed 1/66:55 am -
2 stops9h 40m
Deal found 10/20![Southwest logo]()
$402
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/292:46 pm -
1 stop4h 39m
Sat 1/25:30 am -
1 stop5h 30m
Deal found 10/19![United Airlines logo]()
$414
Best flights from Tucson to Des MoinesDiscover carefully curated flight deals from Tucson to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 21, 2026.
Discover carefully curated flight deals from Tucson to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 21, 2026.
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:30 am -
1 stop8h 20m
Mon 1/116:55 am -
1 stop4h 55m
Deal found 10/20![Southwest logo]()
$286
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/265:29 pm -
1 stop5h 30m
Wed 1/69:00 am -
1 stop7h 42m
Deal found 10/20![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/295:55 pm -
1 stop4h 49m
Sat 1/22:32 pm -
1 stop5h 01m
Deal found 10/19![American Airlines logo]()
$467
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3011:15 am -
1 stop6h 20m
Tue 1/56:30 pm -
1 stop4h 55m
Deal found 10/18![Southwest logo]()
$362
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:30 am -
1 stop5h 01m
Sat 11/75:09 pm -
1 stop5h 25m
Deal found 10/17![United Airlines logo]()
$477
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:30 am -
2 stops9h 58m
Sat 11/285:30 am -
1 stop5h 16m
Deal found 10/17![United Airlines logo]()
$494
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:05 am -
2 stops6h 35m
Sat 11/76:00 pm -
1 stop4h 45m
Deal found 10/17![Southwest logo]()
$510
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2910:45 am -
2 stops9h 38m
Sat 1/25:30 am -
1 stop5h 30m
Deal found 10/18![United Airlines logo]()
$509
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/295:40 am -
2 stops8h 25m
Sat 1/25:55 pm -
2 stops6h 45m
Deal found 10/18![Southwest logo]()
$526
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:25 am -
1 stop5h 26m
Sat 1/25:30 am -
1 stop5h 30m
Deal found 10/18![United Airlines logo]()
$528
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:30 am -
1 stop5h 01m
Thu 11/55:30 am -
1 stop5h 16m
Deal found 10/17![United Airlines logo]()
$557
Last-minute flights from Tucson to Des MoinesDiscover last-minute flight deals from Tucson to Des Moines. Data last updated October 21, 2026 and is based on user searches.
Discover last-minute flight deals from Tucson to Des Moines. Data last updated October 21, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:42 am -
1 stop7h 17m
Sat 10/245:06 am -
1 stop6h 42m
Deal found 10/17![American Airlines logo]()
$629
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:31 pm -
1 stop7h 43m
Tue 11/37:23 am -
1 stop8h 20m
Deal found 10/17![American Airlines logo]()
$557
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:15 am -
2 stops8h 35m
Tue 11/312:05 pm -
1 stop6h 15m
Deal found 10/17![Southwest logo]()
$562
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:30 am -
1 stop5h 01m
Sat 11/75:09 pm -
1 stop5h 25m
Deal found 10/17![United Airlines logo]()
$477
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:05 am -
2 stops6h 35m
Sat 11/76:00 pm -
1 stop4h 45m
Deal found 10/17![Southwest logo]()
$510
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:33 pm -
1 stop7h 53m
Sat 11/217:16 pm -
1 stop6h 01m
Deal found 10/17![American Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/142:00 pm -
2 stops8h 42m
Sat 11/215:30 am -
1 stop5h 16m
Deal found 10/17![United Airlines logo]()
$449
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:00 am -
2 stops9h 20m
Sat 11/215:55 pm -
2 stops6h 45m
Deal found 10/17![Southwest logo]()
$537
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:51 pm -
1 stop7h 45m
Sun 11/295:00 am -
1 stop8h 05m
Deal found 10/16![American Airlines logo]()
$602
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/242:30 pm -
1 stop5h 06m
Sat 11/285:30 am -
1 stop5h 16m
Deal found 10/17![United Airlines logo]()
$453
One-way flights from Tucson to Des MoinesSearch for one-way flight options from Tucson to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 21, 2026.
Search for one-way flight options from Tucson to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 21, 2026.
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1911:19 am -
1 stop8h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![United Airlines logo]()
$229
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:33 pm -
1 stop7h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![American Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am -
2 stops9h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Southwest logo]()
$244
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:56 pm -
1 stop6h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/171:53 pm -
1 stop7h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![American Airlines logo]()
$332
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:42 am -
1 stop4h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![United Airlines logo]()
$361
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:55 am -
2 stops8h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Southwest logo]()
$362
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/205:50 am -
1 stop5h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![United Airlines logo]()
$368
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/187:00 am -
1 stop7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![United Airlines logo]()
$383
Find flight deals from Tucson to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Tucson (TUS) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $272 (Southwest) |
One-way from | $229 (United Airlines) |
Popular in | October |
Cheapest in | August |
Average price | $846 |
Cheapflights Fare Finder
Customize your flight search to find flights from Tucson to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 21, 2026.
Use the filters below to find and compare flights from Tucson to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
TucsonDes Moines
TUS Tucson - DSM Des Moines
TUSDSM
Tucson
Fri 3/19
11:19 am-9:35 pm
1 stop8h 16m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$229
TucsonDes Moines
TUS Tucson - DSM Des Moines
TUSDSM
Tucson
Sat 11/7
3:33 pm-12:26 am
1 stop7h 53m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$239
TucsonDes Moines
TUS Tucson - DSM Des Moines
TUSDSM
Tucson
Thu 12/17
6:30 am-3:50 pm
1 stop8h 20m
Des Moines
Mon 1/11
6:55 am-10:50 am
1 stop4h 55m
$286
TucsonDes Moines
TUS Tucson - DSM Des Moines
TUSDSM
Tucson
Sat 12/26
5:29 pm-11:59 pm
1 stop5h 30m
Des Moines
Wed 1/6
9:00 am-3:42 pm
1 stop7h 42m
$339
TucsonDes Moines
TUS Tucson - DSM Des Moines
TUSDSM
Tucson
Fri 3/19
7:10 am-6:30 pm
2 stops9h 20m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$360
Quickest round-trip
TucsonDes Moines
TUS Tucson - DSM Des Moines
TUSDSM
Tucson
Mon 10/26
9:42 am-4:07 pm
1 stop4h 25m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$361
TucsonDes Moines
TUS Tucson - DSM Des Moines
TUSDSM
Tucson
Sun 11/8
5:55 am-3:50 pm
2 stops8h 55m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$362
TucsonDes Moines
TUS Tucson - DSM Des Moines
TUSDSM
Tucson
Wed 12/30
11:15 am-6:35 pm
1 stop6h 20m
Des Moines
Tue 1/5
6:30 pm-10:25 pm
1 stop4h 55m
$362
TucsonDes Moines
TUS Tucson - DSM Des Moines
TUSDSM
Tucson
Mon 10/26
11:53 am-11:07 pm
2 stops9h 14m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$366
TucsonDes Moines
TUS Tucson - DSM Des Moines
TUSDSM
Tucson
Tue 12/29
5:55 pm-11:44 pm
1 stop4h 49m
Des Moines
Sat 1/2
2:32 pm-6:33 pm
1 stop5h 01m
$467
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Tucson to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Tucson to Des Moines in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Tucson-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Tucson-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Tucson-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Tucson-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Tucson-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Tucson to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Tucson with our price prediction graph.
TUS-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 21, 2026.
Read reviews from past customers who have flown Southwest,United Airlines, andAmerican Airlines from Tucson to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Entertainment
7.4
Crew
8.6
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Entertainment
7.4
Crew
8.6
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Entertainment
7.4
Crew
8.6
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Entertainment
7.4
Crew
8.6
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Tucson to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 21, 2026.
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Tucson and Des Moines flights
Browse other Tucson and Des Moines flight options. Last updated on October 21, 2026.
Other flights from Tucson
Browse through other flights departing from Tucson. Flights are based on user searches made on Cheapflights and were last updated on October 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Tucson to Des Moines
Discover the top 3 airlines that operate flights from Tucson to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$332 | Average$505 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$332 | Average$497 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$396 | Average$452 | FlexibilityNo cancel fee | On-time63% |