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$254+ Cheap flights from Des Moines to Tucson (DSM - TUS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — TUS
May 28 — Jun 41
Thu 5/28
Thu 6/4
1 adult, Economy
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Cheap flight deals from Des Moines to Tucson

Cheapest flights from Des Moines to Tucson
Explore the most affordable flight options available from Des Moines to Tucson. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.

This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:48 pm
DSM
-
TUS
1 stop5h 11m
American Airlines
Wed 6/172:58 pm
TUS
-
DSM
1 stop6h 49m
American Airlines
Deal found 4/27$351
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/209:06 am
DSM
-
TUS
1 stop7h 58m
United Airlines
Sun 5/245:45 am
TUS
-
DSM
1 stop4h 51m
United Airlines
Deal found 4/25$389
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:45 am
DSM
-
TUS
1 stop5h 47m
American Airlines
Sat 5/303:55 pm
TUS
-
DSM
1 stop6h 02m
American Airlines
Deal found 4/26$405
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:02 pm
DSM
-
TUS
1 stop6h 14m
American Airlines
Sun 6/285:50 am
TUS
-
DSM
1 stop5h 49m
American Airlines
Deal found 4/24$425
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:20 am
DSM
-
TUS
1 stop5h 47m
United Airlines
Sun 5/315:45 am
TUS
-
DSM
1 stop4h 51m
United Airlines
Deal found 4/24$427
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/114:48 pm
DSM
-
TUS
1 stop8h 27m
American Airlines
Thu 6/183:54 pm
TUS
-
DSM
1 stop6h 04m
American Airlines
Deal found 4/27$428
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:27 am
DSM
-
TUS
1 stop9h 05m
Delta
Sun 5/317:10 am
TUS
-
DSM
2 stops7h 56m
Delta
Deal found 4/24$432
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:25 am
DSM
-
TUS
2 stops9h 45m
Southwest
Sun 6/287:10 am
TUS
-
DSM
2 stops8h 20m
Southwest
Deal found 4/24$433
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:17 pm
DSM
-
TUS
1 stop4h 55m
United Airlines
Wed 6/35:45 am
TUS
-
DSM
1 stop4h 51m
United Airlines
Deal found 4/26$441

Find flight deals from Des Moines to Tucson

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Tucson (TUS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$351
(American Airlines)

One-way from

$254
(American Airlines)

Popular in

November

Cheapest in

August

Average price

$439
Provider with most accurate pricing for Des Moines-Tucson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Tucson flights.
Search Deals
From Des Moines to Tucson
Search Deals
One-way flight from Des Moines to Tucson
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($51 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Tucson that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Des Moines to Tucson that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesTucson

DSM - TUS

DSMTUS

Des Moines

Wed 6/10

4:48 pm-7:59 pm

1 stop5h 11m

Tucson

Wed 6/17

2:58 pm-11:47 pm

1 stop6h 49m

$351

Des MoinesTucson

DSM - TUS

DSMTUS

Des Moines

Wed 5/20

9:06 am-3:04 pm

1 stop7h 58m

Tucson

Sun 5/24

5:45 am-12:36 pm

1 stop4h 51m

$389

Des MoinesTucson

DSM - TUS

DSMTUS

Des Moines

Sun 5/24

6:20 am-10:07 am

1 stop5h 47m

Tucson

Sun 5/31

5:45 am-12:36 pm

1 stop4h 51m

$427

Des MoinesTucson

DSM - TUS

DSMTUS

Des Moines

Thu 7/16

4:40 pm-11:40 pm

2 stops9h 00m

Tucson

Mon 7/20

3:15 pm-10:20 pm

1 stop5h 05m

$432

Des MoinesTucson

DSM - TUS

DSMTUS

Des Moines

Fri 6/26

1:30 pm-7:20 pm

1 stop7h 50m

Tucson

Mon 6/29

2:25 pm-11:30 pm

2 stops7h 05m

$432
Quickest round-trip

Des MoinesTucson

DSM - TUS

DSMTUS

Des Moines

Tue 6/2

5:17 pm-8:12 pm

1 stop4h 55m

Tucson

Wed 6/3

5:45 am-12:36 pm

1 stop4h 51m

$441

Des MoinesTucson

DSM - TUS

DSMTUS

Des Moines

Wed 6/10

6:25 am-2:10 pm

2 stops9h 45m

Tucson

Wed 6/17

5:40 am-6:20 pm

2 stops10h 40m

$484

Des MoinesTucson

DSM - TUS

DSMTUS

Des Moines

Wed 5/20

6:55 am-11:55 am

2 stops7h 00m

Tucson

Sun 5/24

6:40 am-3:20 pm

1 stop6h 40m

$492

Des MoinesTucson

DSM - TUS

DSMTUS

Des Moines

Fri 6/12

1:30 pm-7:20 pm

1 stop7h 50m

Tucson

Fri 6/19

7:15 am-10:20 pm

2 stops13h 05m

$507
Cheapest one-way
Quickest one-way

Des MoinesTucson

DSM - TUS

DSMTUS

Des Moines

Wed 5/13

7:05 pm-10:55 pm

1 stop5h 50m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/25

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Compare providers for flights from Des Moines to Tucson

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Tucson in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Tucson flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Tucson flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Tucson flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Tucson flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Tucson flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Tucson

Have a flexible travel schedule? Discover the best time to fly to Tucson from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Tucson

What is the cheapest month to book a flight from Des Moines to Tucson?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Tucson (average of $309). Flying from Des Moines to Tucson in November is currently the most expensive (average of $626). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Tucson?

Reviews of airlines servicing Tucson

Get insights into the airlines that provide service to Tucson. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Tucson. Reviews last updated April 28, 2026.
Read reviews from past customers who have flown Southwest,United Airlines, andAmerican Airlines from Des Moines to Tucson. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,314 reviews

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,314 reviews
Southwest
8.0
Very good
4,314 reviews

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
United Airlines
7.4
Good
9,672 reviews
Southwest
8.0
Very good
4,314 reviews

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,677 reviews
Southwest
8.0
Very good
4,314 reviews

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Tucson. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Tucson?

    Departing from Des Moines to Tucson will take you 5h 11m. Airlines will cover a distance of 1152 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Des Moines to Tucson round-trip?

    According to our current data, American Airlines ($182), Southwest ($299), and United Airlines ($360) offers the cheapest pricing from Des Moines to Tucson. You may be able to fly from Des Moines to Tucson for 59% less than the average price by searching for these airlines.

  • Can I find deals for flights from Des Moines to Tucson that include hotel bookings?

    Yes. In addition to deals on Des Moines to Tucson flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Tucson?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Tucson.

  • Can I find deals for business class flights from Des Moines to Tucson?

    Yes. Cheapflights offers flight deals from Des Moines to Tucson by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Tucson?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Tucson (average of $309). Flying from Des Moines to Tucson in November is currently the most expensive (average of $626). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Tucson?

Book flights to Tucson if you plan to visit one of these locations
Sierra Vista
Bisbee

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Top 3 airlines flying from Des Moines to Tucson

Discover the top 3 airlines that operate flights from Des Moines to Tucson. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$182Average$443FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$299Average$496FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$360Average$449FlexibilityNo cancel feeOn-time69%

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