HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
North America

$48+ Cheap flights from Missouri to North America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — LAX
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to North America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to North America

Cheapest flights from Missouri to North America
Explore the most affordable flight options available from Missouri to North America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

This Priceline deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:45 pmMCI - PHX
1 stop4h 44mFrontier
Thu 1/17:20 amPHX - MCI
Nonstop2h 38mFrontier
Deal found 12/25$261
This United Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:35 pmSTL - EWR
1 stop4h 51mUnited Airlines
Thu 1/111:30 amEWR - STL
1 stop7h 24mUnited Airlines
Deal found 12/27$261
This Kiwi.com deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2910:10 pmSTL - LAS
Nonstop3h 52mFrontier
Thu 2/53:50 pmLAS - STL
Nonstop3h 16mFrontier
Deal found 12/27$280
This Mytrip deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:45 pmMCI - PHX
1 stop25h 41mFrontier
Sat 1/313:55 pmPHX - MCI
1 stop26h 56mFrontier
Deal found 12/25$285
This United Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:10 pmSTL - EWR
1 stop7h 05mUnited Airlines
Wed 1/78:35 amEWR - STL
Nonstop3h 06mUnited Airlines
Deal found 12/26$293
This Cheapflightsfares deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:45 pmMCI - PHX
1 stop4h 44mFrontier
Mon 1/128:17 amPHX - MCI
Nonstop2h 38mFrontier
Deal found 12/26$294
This Travelocity deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:45 pmMCI - MCO
1 stop7h 46mMultiple Airlines
Wed 2/41:55 pmMCO - MCI
Nonstop3h 14mMultiple Airlines
Deal found 12/26$299
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:00 amSTL - LGA
1 stop5h 04mAmerican Airlines
Thu 1/17:59 amLGA - STL
1 stop6h 15mAmerican Airlines
Deal found 12/26$303
This Cheapflightsfares deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:47 pmMCI - MCO
Nonstop2h 56mSpirit Airlines
Sat 1/38:52 pmMCO - MCI
Nonstop3h 07mSpirit Airlines
Deal found 12/27$304
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amSTL - LGA
1 stop6h 12mDelta
Thu 1/111:25 amLGA - STL
Nonstop2h 52mDelta
Deal found 12/26$307
This Cheapflightsfares deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/303:47 pmMCI - MCO
Nonstop2h 56mSpirit Airlines
Fri 1/28:52 pmMCO - MCI
Nonstop3h 07mSpirit Airlines
Deal found 12/26$308
This Cheapflightsfares deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:47 pmMCI - MCO
Nonstop2h 56mSpirit Airlines
Thu 1/18:52 pmMCO - MCI
Nonstop3h 07mSpirit Airlines
Deal found 12/27$313

Find flight deals from Missouri to North America

Keep the following information in mind while searching for Missouri to North America flight deals. Data was last updated December 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$66
(Kiwi.com)

One-way from

$48
(Kiwi.com)

Popular in

November

Cheapest in

April

Average price

$357

Good round-trip deal

$95 or less

Good one-way deal

$64 or less
Provider with most accurate pricing for Lambert-St Louis-New York (NYC) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-New York (NYC) flights.
Search Deals
From Missouri to North America
Search Deals
One-way flight from Missouri to North America
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Missouri to North America.
Search Deals
Price to beat on a one-way flight from Missouri to North America.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to North America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Missouri to North America that are best for you.

Fly from

Missouri

Fly to

North America

Route

Depart

Return

Price

St. LouisOrlando

STL - MCO

STLMCO

Lambert-St Louis

Sun 1/18

5:11 pm-8:27 pm

Nonstop2h 16m

Orlando

Sat 1/24

9:20 am-11:11 am

Nonstop2h 51m

$78

St. LouisOrlando

STL - MCO

STLMCO

Lambert-St Louis

Sun 2/8

8:59 am-12:27 pm

Nonstop2h 28m

Orlando

Mon 2/16

10:16 pm-11:59 pm

Nonstop2h 43m

$142

St. LouisOrlando

STL - MCO

STLMCO

Lambert-St Louis

Wed 1/28

5:42 pm-8:58 pm

Nonstop2h 16m

Orlando

Sun 2/1

1:45 pm-12:50 pm

1 stop24h 05m

$144

Kansas CityOrlando

MCI - MCO

MCIMCO

Kansas City

Mon 1/26

5:04 pm-8:51 pm

Nonstop2h 47m

Orlando

Sun 2/1

6:00 am-10:31 am

1 stop5h 31m

$153

Kansas CityLas Vegas

MCI - LAS

MCILAS

Kansas City

Sat 2/21

8:36 pm-11:44 pm

1 stop5h 08m

Las Vegas Harry Reid Intl

Thu 2/26

10:59 am-5:59 pm

1 stop5h 00m

$154

St. LouisOrlando

STL - MCO

STLMCO

Lambert-St Louis

Fri 1/23

3:50 pm-10:00 pm

1 stop5h 10m

Orlando

Fri 1/30

9:30 am-11:15 am

Nonstop2h 45m

$157

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Sun 1/18

11:49 am-2:12 pm

Nonstop3h 23m

Phoenix Sky Harbor Intl

Wed 1/21

4:21 pm-11:33 pm

1 stop6h 12m

$157

St. LouisOrlando

STL - MCO

STLMCO

Lambert-St Louis

Sun 3/8

4:51 pm-8:13 pm

Nonstop2h 22m

Orlando

Fri 3/13

5:30 am-7:22 am

Nonstop2h 52m

$158

St. LouisOrlando

STL - MCO

STLMCO

Lambert-St Louis

Tue 1/20

8:20 am-1:25 pm

1 stop4h 05m

Orlando

Sat 1/31

6:10 am-1:50 pm

1 stop8h 40m

$167

Kansas CityOrlando

MCI - MCO

MCIMCO

Kansas City

Mon 2/16

4:24 pm-8:12 pm

Nonstop2h 48m

Orlando

Mon 2/23

6:00 am-10:30 am

1 stop5h 30m

$170

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Missouri to North America

Have a flexible travel schedule? Discover the best time to fly to North America from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to North America

What is the cheapest month to book a flight from Missouri to North America?

Currently, January is the cheapest month in which you can book a flight from Missouri to North America (average of $48). Flying from Missouri to North America in June is currently the most expensive (average of $108). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to NA?

Find hourly flight availability from Missouri to North America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 28, 2025.

It’s typically best to fly out from Missouri to North America in the evening. Doing so could potentially save you 7% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Missouri to North America?

Use this chart to determine the cheapest time to fly round-trip from Missouri to North America. Price data was last updated on December 27, 2025.

Travelers seeking maximum savings on their Missouri to North America flight should consider departing on Sunday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Missouri to North America

Explore weekly flight availability from Missouri to North America. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 28, 2025.

The most flights from USMO to 0NA are scheduled on a Monday (11 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (8 on average).

Reviews of airlines servicing North America

Get insights into the airlines that provide service to North America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North America. Reviews last updated December 28, 2025.
Read reviews from past customers who have flown Southwest from Missouri to North America. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,256 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,256 reviews
Southwest
8.0
Very good
4,256 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Missouri to North America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Missouri to North America flight route?

    The Missouri to North America flight path was viewed by 17 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to North America?

    Departing from Missouri to North America will take you 2h 16m. Airlines will cover a distance of 882 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to North America one-way?

    One-way options have recently been found by users for as low as $30 on Spirit Airlines. Other airlines that offer cheap prices include Frontier from $30 and Southern / Mokulele from $33 one-way.

  • Can I find deals for flights from Missouri to North America that include hotel bookings?

    Yes. In addition to deals on Missouri to North America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to North America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to North America.

  • Can I find deals for business class flights from Missouri to North America?

    Yes. Cheapflights offers flight deals from Missouri to North America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to North America?

    Currently, January is the cheapest month in which you can book a flight from Missouri to North America (average of $48). Flying from Missouri to North America in June is currently the most expensive (average of $108). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to North America

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Fort Lauderdale flights
Newark to Fort Lauderdale flights
John F Kennedy Intl to Cancún flights
John F Kennedy Intl to Miami flights
LaGuardia to Fort Lauderdale flights
Newark to Miami flights
LaGuardia to Miami flights
Newark to Cancún flights
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Las Vegas flights
Los Angeles to John F Kennedy Intl flights
Los Angeles to Haneda flights
Newark to West Palm Beach flights
Newark to Las Vegas flights
Newark to Orlando flights
O'Hare Intl to Cancún flights
O'Hare Intl to Las Vegas flights
John F Kennedy Intl to West Palm Beach flights
Dallas/Fort Worth to Las Vegas flights
John F Kennedy Intl to Heathrow flights
John F Kennedy Intl to Luis Munoz Marin Intl flights
John F Kennedy Intl to Orlando flights
LaGuardia to Orlando flights
Dulles Intl to Cancún flights
Newark to Luis Munoz Marin Intl flights
John F Kennedy Intl to Mexico City flights
San Francisco to Las Vegas flights
Newark to Heathrow flights
Minneapolis to Sky Harbor Intl flights
O'Hare Intl to Dallas/Fort Worth flights
Dallas/Fort Worth to LaGuardia flights
John F Kennedy Intl to Charles de Gaulle flights
LaGuardia to Cancún flights
Dallas/Fort Worth to Cancún flights
Boston to Fort Lauderdale flights
John F Kennedy Intl to Dallas/Fort Worth flights
Newark to Mexico City flights
John F Kennedy Intl to Haneda flights
Dallas/Fort Worth to John F Kennedy Intl flights
Los Angeles to Narita flights
Boston to Orlando flights
Boston to Miami flights
Seattle to Los Angeles flights
Dulles Intl to Miami flights
Los Angeles to Newark flights
O'Hare Intl to John F Kennedy Intl flights
Dallas/Fort Worth to O'Hare Intl flights
O'Hare Intl to Sky Harbor Intl flights
John F Kennedy Intl to Sky Harbor Intl flights
LaGuardia to Dallas/Fort Worth flights

Top 9 airlines flying from Missouri to North America

Discover the top 9 airlines that operate flights from Missouri to North America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$71Average$222FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$73Average$213FlexibilityNo cancel feeOn-time65%
Allegiant AirCheapest$130Average$234FlexibilityNo cancel feeOn-time88%
DeltaCheapest$133Average$407FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$150Average$438FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$180Average$440FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$187Average$431FlexibilityNo cancel feeOn-time63%
Alaska AirlinesCheapest$256Average$441FlexibilityNo cancel feeOn-time75%
AeromexicoCheapest$487Average$624FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.