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$44+ Cheap flights from Missouri to North America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
STL — LAX
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Missouri to North America

Keep the following information in mind while searching for Missouri to North America flight deals. Data was last updated September 17, 2025.

Round-trip from

$131
(Cheapflightsfares)

One-way from

$44
(Cheapflightsfares)

Popular in

December

Cheapest in

October

Average price

$298

Good round-trip deal

$78 or less

Good one-way deal

$61 or less
From Missouri to North America
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One-way flight from Missouri to North America
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Highest demand for flights based on searches. 7% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Missouri to North America.
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Price to beat on a one-way flight from Missouri to North America.
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Find flight deals from Missouri to North America

Cheapest flights from Missouri to North America
Explore the most affordable flight options available from Missouri to North America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/106:05 pmSTL - MCO
Nonstop2h 25mFrontier
Sun 10/1211:07 amMCO - STL
Nonstop2h 39mFrontier
Deal found 9/16$131
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/114:33 pmSTL - MCO
Nonstop2h 23mFrontier
Sun 10/126:00 amMCO - STL
1 stop28h 07mFrontier
Deal found 9/15$132
This Frontier deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/294:00 pmSTL - MCO
1 stop7h 09mFrontier
Sun 10/1211:07 amMCO - STL
Nonstop2h 39mFrontier
Deal found 9/17$133
This Frontier deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/69:32 pmSTL - MCO
Nonstop2h 27mFrontier
Thu 10/93:29 pmMCO - STL
Nonstop2h 41mFrontier
Deal found 9/16$134
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/212:55 pmMCI - LAS
Nonstop3h 02mSpirit Airlines
Tue 10/289:07 amLAS - MCI
Nonstop2h 53mSpirit Airlines
Deal found 9/15$134
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/142:55 pmMCI - LAS
Nonstop3h 02mSpirit Airlines
Tue 10/219:07 amLAS - MCI
Nonstop2h 53mSpirit Airlines
Deal found 9/14$135
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/18:28 pmMCI - LAS
1 stop5h 01mMultiple Airlines
Sat 11/87:47 pmLAS - MCI
Nonstop2h 53mMultiple Airlines
Deal found 9/16$137
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/14:51 pmSTL - LAS
Nonstop3h 39mFrontier
Thu 11/68:48 pmLAS - STL
1 stop10h 19mFrontier
Deal found 9/15$137
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/114:33 pmSTL - MCO
Nonstop2h 23mMultiple Airlines
Sun 10/196:06 amMCO - STL
1 stop4h 56mMultiple Airlines
Deal found 9/17$138
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/82:55 pmMCI - LAS
Nonstop3h 02mMultiple Airlines
Sat 10/1110:07 amLAS - MCI
1 stop5h 48mMultiple Airlines
Deal found 9/17$138
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:11 pmSTL - MCO
Nonstop2h 28mFrontier
Tue 12/168:56 pmMCO - STL
Nonstop2h 50mFrontier
Deal found 9/15$139
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/157:02 pmMCI - LAS
1 stop6h 27mMultiple Airlines
Wed 10/229:07 amLAS - MCI
Nonstop2h 53mMultiple Airlines
Deal found 9/15$139

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to North America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Missouri to North America that are best for you.

Fly from

Missouri

Fly to

North America

Route

Depart

Return

Price

St. LouisOrlando

STL - MCO

STLMCO

Lambert-St Louis

Thu 10/23

1:41 pm-5:05 pm

Nonstop2h 24m

Orlando

Thu 10/30

11:38 am-1:17 pm

Nonstop2h 39m

$148

St. LouisOrlando

STL - MCO

STLMCO

Lambert-St Louis

Tue 11/18

7:00 am-2:24 pm

1 stop6h 24m

Orlando

Mon 11/24

10:30 am-3:46 pm

1 stop6h 16m

$151

St. LouisOrlando

STL - MCO

STLMCO

Lambert-St Louis

Wed 11/19

7:00 am-2:24 pm

1 stop6h 24m

Orlando

Fri 11/21

9:40 am-3:46 pm

1 stop7h 06m

$151

St. LouisOrlando

STL - MCO

STLMCO

Lambert-St Louis

Thu 11/13

7:45 pm-5:44 am

1 stop8h 59m

Orlando

Sun 11/16

5:25 am-10:12 am

1 stop5h 47m

$152

St. LouisOrlando

STL - MCO

STLMCO

Lambert-St Louis

Thu 11/13

7:45 pm-5:44 am

1 stop8h 59m

Orlando

Mon 11/17

8:00 am-9:40 am

Nonstop2h 40m

$154

St. LouisOrlando

STL - MCO

STLMCO

Lambert-St Louis

Wed 11/12

11:33 am-6:45 pm

1 stop6h 12m

Orlando

Sat 11/15

5:15 am-12:37 pm

1 stop8h 22m

$159

St. LouisOrlando

STL - MCO

STLMCO

Lambert-St Louis

Mon 9/29

4:00 pm-12:09 am

1 stop7h 09m

Orlando

Wed 10/15

8:59 pm-9:07 am

1 stop13h 08m

$162

St. LouisLas Vegas

STL - LAS

STLLAS

Lambert-St Louis

Mon 11/24

4:43 pm-8:45 pm

1 stop6h 02m

Las Vegas Harry Reid Intl

Wed 11/26

12:59 am-10:39 am

1 stop7h 40m

$167

St. LouisOrlando

STL - MCO

STLMCO

Lambert-St Louis

Tue 11/18

2:36 pm-8:39 pm

1 stop5h 03m

Orlando

Fri 11/28

6:15 am-10:04 am

1 stop4h 49m

$197

Kansas CityLas Vegas

MCI - LAS

MCILAS

Kansas City

Tue 12/9

5:10 pm-9:00 pm

1 stop5h 50m

Las Vegas Harry Reid Intl

Sat 12/13

1:35 pm-11:07 pm

2 stops7h 32m

$200

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to North America

Have a flexible travel schedule? Discover the best time to fly to North America from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to North America

What is the cheapest month to book a flight from Missouri to North America?

Currently, January is the cheapest month in which you can book a flight from Missouri to North America (average of $246). Flying from Missouri to North America in March is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to NA?

Find hourly flight availability from Missouri to North America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

When flying from Missouri to North America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Missouri to North America

Explore weekly flight availability from Missouri to North America. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 17, 2025.

The most flights from USMO to 0NA are scheduled on a Monday (10 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing North America

Get insights into the airlines that provide service to North America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North America. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown Southwest from Missouri to North America. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Missouri to North America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Missouri to North America flight route?

    The Missouri to North America flight path was viewed by 15 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to North America?

    Departing from Missouri to North America will take you 2h 24m. Airlines will cover a distance of 882 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to North America one-way?

    One-way options have recently been found by users for as low as $67 on Spirit Airlines. Other airlines that offer cheap prices include Frontier from $72 and American Airlines from $80 one-way.

  • Can I find deals for flights from Missouri to North America that include hotel bookings?

    Yes. In addition to deals on Missouri to North America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to North America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to North America.

  • Can I find deals for business class flights from Missouri to North America?

    Yes. Cheapflights offers flight deals from Missouri to North America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to North America?

    Currently, January is the cheapest month in which you can book a flight from Missouri to North America (average of $246). Flying from Missouri to North America in March is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to North America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from Missouri to North America

Discover the top 10 airlines that operate flights from Missouri to North America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$46Average$213FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$76Average$209FlexibilityNo cancel feeOn-time65%
Allegiant AirCheapest$104Average$233FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$126Average$430FlexibilityNo cancel feeOn-time69%
DeltaCheapest$128Average$388FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$142Average$404FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$157Average$446FlexibilityNo cancel feeOn-time71%
Southern / MokuleleCheapest$194Average$264FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$256Average$432FlexibilityNo cancel feeOn-time75%
AeromexicoCheapest$487Average$598FlexibilityNo cancel feeOn-timeN/A

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