$176+ Cheap flights from San Francisco to St. Louis (SFO - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — STL
Oct 21 — Oct 281
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Francisco to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Francisco to Lambert-St Louis are usually found in April or November, booked 82 days in advance, depart on a Wednesday or Thursday and return on a Thursday
Cheap flight deals from San Francisco to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Francisco to St. LouisExplore the most affordable flight options available from San Francisco to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from San Francisco to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This Frontier deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:24 pm -
1 stop12h 53m
Mon 10/58:10 pm -
1 stop6h 04m
Deal found 9/16![Frontier logo]()
$388
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:20 pm -
1 stop5h 49m
Mon 11/93:30 pm -
2 stops10h 01m
Deal found 9/18![Delta logo]()
$390
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:02 am -
1 stop27h 01m
Sat 11/213:04 pm -
1 stop11h 39m
Deal found 9/18![Frontier logo]()
$391
This Alaska Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/71:51 pm -
1 stop8h 08m
Tue 10/137:02 am -
2 stops11h 14m
Deal found 9/18![Alaska Airlines logo]()
$392
This Mytrip deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:04 am -
1 stop11h 13m
Wed 10/72:29 pm -
2 stops11h 45m
Deal found 9/18![Frontier logo]()
$393
This Booking.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:14 pm -
2 stops20h 26m
Thu 10/292:00 pm -
3 stops20h 19m
Deal found 9/18![Multiple Airlines logo]()
$394
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:04 am -
1 stop11h 13m
Thu 10/154:30 pm -
2 stops33h 45m
Deal found 9/20![Frontier logo]()
$395
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:19 pm -
1 stop12h 16m
Sun 10/1812:16 pm -
1 stop21h 57m
Deal found 9/17![Frontier logo]()
$396
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:15 pm -
Nonstop3h 50m
Thu 10/298:00 am -
Nonstop4h 36m
Deal found 9/18![United Airlines logo]()
$397
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:23 pm -
2 stops18h 51m
Sun 11/81:28 pm -
2 stops28h 34m
Deal found 9/17![Frontier logo]()
$398
This Cheapflightsfares deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2111:29 pm -
1 stop6h 25m
Fri 11/273:04 pm -
1 stop11h 39m
Deal found 9/20![Frontier logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:42 am -
1 stop5h 35m
Tue 10/612:17 pm -
2 stops29h 16m
Deal found 9/17![Frontier logo]()
$401
Best flights from San Francisco to St. LouisDiscover carefully curated flight deals from San Francisco to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from San Francisco to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:50 am -
1 stop5h 42m
Tue 10/2712:28 pm -
2 stops9h 50m
Deal found 9/16![Delta logo]()
$393
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:15 pm -
Nonstop3h 50m
Thu 10/298:00 am -
Nonstop4h 36m
Deal found 9/18![United Airlines logo]()
$397
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:05 pm -
Nonstop3h 45m
Mon 11/24:30 pm -
1 stop8h 50m
Deal found 9/16![Southwest logo]()
$473
This Alaska Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:51 pm -
1 stop8h 08m
Wed 10/76:04 am -
2 stops13h 57m
Deal found 9/20![Alaska Airlines logo]()
$498
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:38 am -
2 stops10h 40m
Mon 11/232:20 pm -
2 stops11h 11m
Deal found 9/16![Delta logo]()
$403
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:25 pm -
Nonstop3h 50m
Wed 11/118:50 am -
1 stop6h 22m
Deal found 9/21![United Airlines logo]()
$460
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:00 am -
1 stop7h 45m
Sat 1/166:20 am -
1 stop6h 40m
Deal found 9/20![Southwest logo]()
$487
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2511:20 pm -
Nonstop4h 06m
Wed 12/306:58 pm -
1 stop8h 01m
Deal found 9/19![United Airlines logo]()
$462
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:35 am -
2 stops8h 34m
Sun 10/256:21 am -
1 stop6h 31m
Deal found 9/19![Delta logo]()
$476
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:15 pm -
Nonstop3h 50m
Mon 11/96:15 am -
1 stop8h 04m
Deal found 9/19![United Airlines logo]()
$489
Last-minute flights from San Francisco to St. LouisDiscover last-minute flight deals from San Francisco to St. Louis. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to St. Louis. Data last updated September 21, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:42 am -
1 stop5h 35m
Tue 10/612:17 pm -
2 stops29h 16m
Deal found 9/17![Frontier logo]()
$401
This Frontier deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:24 pm -
1 stop12h 53m
Mon 10/58:10 pm -
1 stop6h 04m
Deal found 9/16![Frontier logo]()
$388
This Mytrip deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:04 am -
1 stop11h 13m
Wed 10/72:29 pm -
2 stops11h 45m
Deal found 9/18![Frontier logo]()
$393
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:04 am -
1 stop11h 13m
Thu 10/154:30 pm -
2 stops33h 45m
Deal found 9/20![Frontier logo]()
$395
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/410:05 pm -
1 stop13h 05m
Tue 10/67:02 am -
1 stop9h 21m
Deal found 9/20![Multiple Airlines logo]()
$404
This Alaska Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/71:51 pm -
1 stop8h 08m
Tue 10/137:02 am -
2 stops11h 14m
Deal found 9/18![Alaska Airlines logo]()
$392
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:19 pm -
1 stop12h 16m
Sun 10/1812:16 pm -
1 stop21h 57m
Deal found 9/17![Frontier logo]()
$396
This Expedia deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:03 am -
2 stops14h 56m
Sat 10/245:40 am -
2 stops14h 21m
Deal found 9/17![Alaska Airlines logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:19 pm -
1 stop12h 16m
Fri 10/306:44 pm -
2 stops21h 36m
Deal found 9/20![Frontier logo]()
$405
This Booking.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:14 pm -
2 stops20h 26m
Thu 10/292:00 pm -
3 stops20h 19m
Deal found 9/18![Multiple Airlines logo]()
$394
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:15 pm -
Nonstop3h 50m
Thu 10/298:00 am -
Nonstop4h 36m
Deal found 9/18![United Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:58 pm -
2 stops11h 40m
Mon 11/25:38 pm -
1 stop8h 18m
Deal found 9/17![Delta logo]()
$403
One-way flights from San Francisco to St. LouisSearch for one-way flight options from San Francisco to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
Search for one-way flight options from San Francisco to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:15 pm -
2 stops9h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Southwest logo]()
$176
This Cheapflightsfares deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/82:21 pm -
1 stop20h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Frontier logo]()
$178
This Frontier deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2111:29 pm -
1 stop6h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Frontier logo]()
$179
This Expedia deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/285:05 am -
1 stop11h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Frontier logo]()
$185
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:15 pm -
Nonstop3h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![United Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:44 am -
2 stops24h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Frontier logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:57 pm -
2 stops40h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$191
This Frontier deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/209:23 pm -
1 stop11h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1811:59 pm -
1 stop14h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:59 pm -
2 stops18h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 am -
1 stop11h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Frontier logo]()
$196
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:41 am -
1 stop7h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$197
Find flight deals from San Francisco to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $388 (Frontier) |
One-way from | $176 (Southwest) |
Popular in | March |
Cheapest in | April |
Average price | $518 |
Good round-trip deal | $486 or less |
Good one-way deal | $258 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from San Francisco to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San FranciscoSt. Louis
SFO San Francisco - STL Lambert-St Louis
SFOSTL
San Francisco
Fri 10/30
12:15 pm-6:05 pm
Nonstop3h 50m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$213
San FranciscoSt. Louis
SFO San Francisco - STL Lambert-St Louis
SFOSTL
San Francisco
Tue 11/17
12:15 pm-6:05 pm
Nonstop3h 50m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$221
San FranciscoSt. Louis
SFO San Francisco - STL Lambert-St Louis
SFOSTL
San Francisco
Wed 10/14
12:45 pm-6:43 pm
Nonstop3h 58m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$222
San FranciscoSt. Louis
SFO San Francisco - STL Lambert-St Louis
SFOSTL
San Francisco
Sat 10/17
12:45 pm-6:43 pm
Nonstop3h 58m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$222
San FranciscoSt. Louis
SFO San Francisco - STL Lambert-St Louis
SFOSTL
San Francisco
Fri 10/16
5:13 pm-12:44 am
1 stop5h 31m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$250
San FranciscoSt. Louis
SFO San Francisco - STL Lambert-St Louis
SFOSTL
San Francisco
Mon 10/12
9:54 am-12:44 am
2 stops12h 50m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$254
San FranciscoSt. Louis
SFO San Francisco - STL Lambert-St Louis
SFOSTL
San Francisco
Mon 11/16
12:15 pm-6:05 pm
Nonstop3h 50m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$259
San FranciscoSt. Louis
SFO San Francisco - STL Lambert-St Louis
SFOSTL
San Francisco
Sat 10/17
6:20 am-9:09 pm
2 stops12h 49m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$272
San FranciscoSt. Louis
SFO San Francisco - STL Lambert-St Louis
SFOSTL
San Francisco
Wed 12/16
12:20 pm-6:11 pm
Nonstop3h 51m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$274
San FranciscoSt. Louis
SFO San Francisco - STL Lambert-St Louis
SFOSTL
San Francisco
Fri 10/16
12:45 pm-6:43 pm
Nonstop3h 58m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$274
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from San Francisco to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to St. Louis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from San Francisco with our price prediction graph.
SFO-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to St. Louis
How far ahead should I book a flight from San Francisco to St. Louis?
To ensure you get the cheapest price possible for a flight from San Francisco to St. Louis, you should look to book at least 81 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from San Francisco to St. Louis?
Currently, April is the cheapest month in which you can book a flight from San Francisco to St. Louis (average of $488). Flying from San Francisco to St. Louis in March is currently the most expensive (average of $623). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SFO to STL?
Find hourly flight availability from San Francisco to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 21, 2026.
It’s optimal to fly from San Francisco to St. Louis at noon. By choosing this option you can save up to 36% on the cost of your flight, compared to a flight in the afternoon.
The best insider tips for San Francisco to St. Louis flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your San Francisco to St. Louis trip
Our travel experts
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 21, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from San Francisco to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Maryland Heights
Collinsville
Edwardsville
Glencoe
Chesterfield
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from San Francisco
Popular flights
St. Louis flight routes
Alternative routes for San Francisco to St. Louis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Francisco to St. Louis by cabin class
Find flights from San Francisco to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Francisco and St. Louis flights
Browse other San Francisco and St. Louis flight options. Last updated on September 21, 2026.
Other flights from San Francisco
Browse through other flights departing from San Francisco. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Top 6 airlines flying from San Francisco to St. Louis
Discover the top 6 airlines that operate flights from San Francisco to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$118 | Average$471 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$138 | Average$354 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$290 | Average$527 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$356 | Average$595 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$381 | Average$565 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$389 | Average$514 | FlexibilityNo cancel fee | On-time75% |