$77+ Cheap flights from San Francisco (SFO) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — STL
Apr 9 — Apr 161
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Missouri with Cheapflights
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Cheapest flights from San Francisco to MissouriExplore the most affordable flight options available from San Francisco to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
Explore the most affordable flight options available from San Francisco to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:09 pm
SFO
- MCI
2 stops19h 00m
Multiple Airlines
Mon 4/68:43 pm
MCI
- SFO
1 stop29h 45m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$278
This Expedia deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:13 am
SFO
- MCI
1 stop10h 46m
Multiple Airlines
Tue 4/78:43 pm
MCI
- SFO
1 stop5h 45m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$280
This Expedia deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
SFO
- MCI
1 stop5h 30m
Frontier
Sun 5/32:15 pm
MCI
- SFO
1 stop20h 58m
Frontier
Deal found 3/7![Frontier logo]()
$281
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:55 am
SFO
- MCI
2 stops9h 38m
Delta
Sat 5/167:26 am
MCI
- SFO
1 stop8h 10m
Delta
Deal found 3/9![Delta logo]()
$282
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:45 am
SFO
- MCI
1 stop6h 17m
American Airlines
Sun 8/233:00 pm
MCI
- SFO
1 stop5h 58m
American Airlines
Deal found 3/9![American Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:14 pm
SFO
- MCI
2 stops21h 44m
Multiple Airlines
Mon 4/136:04 pm
MCI
- SFO
1 stop26h 41m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/39:24 pm
SFO
- MCI
1 stop16h 28m
Multiple Airlines
Thu 5/72:15 pm
MCI
- SFO
2 stops22h 51m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:48 pm
SFO
- MCI
1 stop16h 21m
Multiple Airlines
Fri 4/36:04 pm
MCI
- SFO
1 stop17h 12m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:35 am
SFO
- STL
1 stop7h 25m
Multiple Airlines
Wed 5/68:13 pm
STL
- SFO
2 stops22h 39m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/304:45 pm
SFO
- MCI
Nonstop3h 44m
United Airlines
Sat 4/47:00 am
MCI
- SFO
Nonstop4h 05m
United Airlines
Deal found 3/8![United Airlines logo]()
$289
This Expedia deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
SFO
- STL
1 stop25h 48m
Frontier
Sun 4/510:12 pm
STL
- SFO
1 stop11h 51m
Frontier
Deal found 3/7![Frontier logo]()
$290
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:32 am
SFO
- MCI
2 stops12h 06m
Delta
Tue 4/217:42 am
MCI
- SFO
1 stop8h 23m
Delta
Deal found 3/9![Delta logo]()
$290
Best flights from San Francisco to MissouriDiscover carefully curated flight deals from San Francisco to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
Discover carefully curated flight deals from San Francisco to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:32 am
SFO
- STL
2 stops11h 53m
Delta
Fri 4/172:20 pm
STL
- SFO
2 stops11h 17m
Delta
Deal found 3/7![Delta logo]()
$305
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1511:28 pm
SFO
- COU
1 stop8h 18m
American Airlines
Tue 5/194:28 pm
COU
- SFO
1 stop9h 31m
American Airlines
Deal found 3/5![American Airlines logo]()
$318
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/173:25 pm
SFO
- MCI
1 stop7h 00m
Southwest
Thu 5/215:55 am
MCI
- SFO
1 stop8h 40m
Southwest
Deal found 3/9![Southwest logo]()
$349
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/112:00 pm
SFO
- STL
Nonstop4h 24m
United Airlines
Thu 4/28:30 am
STL
- SFO
Nonstop4h 43m
United Airlines
Deal found 3/8![United Airlines logo]()
$359
This Alaska Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:45 am
SFO
- SGF
2 stops10h 01m
Alaska Airlines
Wed 5/62:33 pm
SGF
- SFO
2 stops10h 28m
Alaska Airlines
Deal found 3/9![Alaska Airlines logo]()
$409
This KAYAK deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:21 pm
SFO
- UIN
2 stops22h 39m
Multiple Airlines
Mon 5/185:25 pm
UIN
- SFO
2 stops19h 24m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$585
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/209:53 am
SFO
- MCI
1 stop6h 22m
Delta
Sun 8/234:00 pm
MCI
- SFO
1 stop7h 35m
Delta
Deal found 3/8![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:00 pm
SFO
- MCI
1 stop8h 10m
Delta
Sat 8/156:40 am
MCI
- SFO
1 stop7h 50m
Delta
Deal found 3/6![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:20 am
SFO
- MCI
2 stops8h 10m
Southwest
Tue 4/1412:25 pm
MCI
- SFO
2 stops8h 05m
Southwest
Deal found 3/9![Southwest logo]()
$359
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:20 pm
SFO
- STL
Nonstop4h 30m
United Airlines
Thu 4/168:15 pm
STL
- SFO
1 stop7h 20m
United Airlines
Deal found 3/8![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/211:35 pm
SFO
- SGF
1 stop9h 32m
Delta
Sat 5/24:00 pm
SGF
- SFO
1 stop8h 47m
Delta
Deal found 3/6![Delta logo]()
$334
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:05 am
SFO
- MCI
2 stops7h 00m
Southwest
Sun 7/265:15 am
MCI
- SFO
1 stop5h 55m
Southwest
Deal found 3/6![Southwest logo]()
$369
This Alaska Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2510:08 pm
SFO
- MCI
1 stop16h 48m
Alaska Airlines
Sun 6/287:58 pm
MCI
- SFO
1 stop15h 22m
Alaska Airlines
Deal found 3/9![Alaska Airlines logo]()
$413
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:45 am
SFO
- MCI
Nonstop3h 45m
United Airlines
Sat 8/155:22 pm
MCI
- SFO
1 stop7h 34m
United Airlines
Deal found 3/6![United Airlines logo]()
$385
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/131:15 pm
SFO
- STL
1 stop8h 35m
Southwest
Tue 4/145:30 am
STL
- SFO
2 stops9h 05m
Southwest
Deal found 3/9![Southwest logo]()
$373
This Alaska Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1110:08 pm
SFO
- MCI
1 stop16h 48m
Alaska Airlines
Tue 6/165:50 pm
MCI
- SFO
1 stop7h 46m
Alaska Airlines
Deal found 3/7![Alaska Airlines logo]()
$428
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:05 am
SFO
- SGF
1 stop7h 16m
United Airlines
Wed 8/266:35 pm
SGF
- SFO
1 stop7h 45m
United Airlines
Deal found 3/8![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:25 am
SFO
- STL
2 stops8h 20m
Southwest
Tue 4/145:30 am
STL
- SFO
2 stops9h 05m
Southwest
Deal found 3/5![Southwest logo]()
$387
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/111:56 pm
SFO
- COU
1 stop8h 59m
United Airlines
Fri 5/85:00 am
COU
- SFO
1 stop10h 23m
United Airlines
Deal found 3/7![United Airlines logo]()
$408
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:31 am
SFO
- STL
2 stops11h 50m
Delta
Thu 4/26:29 am
STL
- SFO
2 stops11h 35m
Delta
Deal found 3/6![Delta logo]()
$415
This KAYAK deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:45 pm
SFO
- TBN
2 stops21h 05m
Multiple Airlines
Sun 8/302:30 pm
TBN
- SFO
2 stops11h 29m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$587
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:50 am
SFO
- COU
1 stop8h 13m
United Airlines
Wed 4/223:23 pm
COU
- SFO
1 stop9h 22m
United Airlines
Deal found 3/7![United Airlines logo]()
$408
This Alaska Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:00 am
SFO
- SGF
2 stops10h 17m
Alaska Airlines
Sat 8/84:18 pm
SGF
- SFO
2 stops9h 11m
Alaska Airlines
Deal found 3/7![Alaska Airlines logo]()
$508
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/204:53 pm
SFO
- STL
1 stop5h 37m
Delta
Sun 5/244:00 pm
STL
- SFO
1 stop6h 37m
Delta
Deal found 3/9![Delta logo]()
$430
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/299:15 pm
SFO
- STL
1 stop10h 45m
Southwest
Wed 6/35:30 am
STL
- SFO
2 stops9h 05m
Southwest
Deal found 3/9![Southwest logo]()
$435
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:52 pm
SFO
- COU
1 stop9h 03m
United Airlines
Tue 5/511:30 am
COU
- SFO
1 stop9h 08m
United Airlines
Deal found 3/8![United Airlines logo]()
$408
This Alaska Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:00 am
SFO
- SGF
2 stops12h 09m
Alaska Airlines
Wed 8/2610:04 am
SGF
- SFO
2 stops11h 36m
Alaska Airlines
Deal found 3/7![Alaska Airlines logo]()
$508
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:45 am
SFO
- COU
1 stop8h 10m
United Airlines
Thu 5/711:30 am
COU
- SFO
1 stop7h 42m
United Airlines
Deal found 3/7![United Airlines logo]()
$408
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:25 am
SFO
- MCI
1 stop5h 55m
Southwest
Mon 4/133:10 pm
MCI
- SFO
2 stops9h 00m
Southwest
Deal found 3/6![Southwest logo]()
$463
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/54:29 pm
SFO
- MCI
Nonstop3h 46m
United Airlines
Mon 6/84:56 pm
MCI
- SFO
1 stop10h 46m
United Airlines
Deal found 3/7![United Airlines logo]()
$424
Last-minute flights from San Francisco to MissouriDiscover last-minute flight deals from San Francisco to Missouri. Data last updated March 10, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Missouri. Data last updated March 10, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2310:38 pm
SFO
- STL
1 stop9h 54m
Frontier
Tue 3/2412:14 pm
STL
- SFO
1 stop8h 23m
Frontier
Deal found 3/5![Frontier logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:48 pm
SFO
- MCI
1 stop16h 21m
Multiple Airlines
Fri 4/36:04 pm
MCI
- SFO
1 stop17h 12m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$288
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/304:45 pm
SFO
- MCI
Nonstop3h 44m
United Airlines
Sat 4/47:00 am
MCI
- SFO
Nonstop4h 05m
United Airlines
Deal found 3/8![United Airlines logo]()
$289
This Expedia deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:13 am
SFO
- MCI
1 stop10h 46m
Multiple Airlines
Tue 4/78:43 pm
MCI
- SFO
1 stop5h 45m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$280
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:01 pm
SFO
- MCI
1 stop5h 45m
Delta
Tue 4/73:45 pm
MCI
- SFO
2 stops10h 12m
Delta
Deal found 3/6![Delta logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:09 pm
SFO
- MCI
2 stops19h 00m
Multiple Airlines
Mon 4/68:43 pm
MCI
- SFO
1 stop29h 45m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$278
This CheapOair deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:00 pm
SFO
- MCI
1 stop21h 01m
Frontier
Sun 4/58:28 pm
MCI
- SFO
1 stop25h 47m
Frontier
Deal found 3/9![Frontier logo]()
$291
This Expedia deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
SFO
- STL
1 stop25h 48m
Frontier
Sun 4/510:12 pm
STL
- SFO
1 stop11h 51m
Frontier
Deal found 3/7![Frontier logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:14 pm
SFO
- MCI
2 stops21h 44m
Multiple Airlines
Mon 4/136:04 pm
MCI
- SFO
1 stop26h 41m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/129:00 pm
SFO
- STL
1 stop10h 48m
Frontier
Wed 4/158:23 pm
STL
- SFO
1 stop23h 11m
Frontier
Deal found 3/9![Frontier logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:35 am
SFO
- STL
1 stop7h 25m
Multiple Airlines
Wed 5/68:13 pm
STL
- SFO
2 stops22h 39m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:32 am
SFO
- MCI
2 stops12h 06m
Delta
Tue 4/217:42 am
MCI
- SFO
1 stop8h 23m
Delta
Deal found 3/9![Delta logo]()
$290
One-way flights from San Francisco to MissouriSearch for one-way flight options from San Francisco to Missouri. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
Search for one-way flight options from San Francisco to Missouri. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:00 am
SFO
- MCI
1 stop6h 06m
Frontier
Deal found 3/6![Frontier logo]()
$77
This Trip.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:00 am
SFO
- STL
1 stop11h 32m
Frontier
Deal found 3/10![Frontier logo]()
$90
This Trip.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
SFO
- STL
1 stop11h 32m
Frontier
Deal found 3/10![Frontier logo]()
$93
This CheapOair deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:38 pm
SFO
- STL
1 stop9h 52m
Frontier
Deal found 3/10![Frontier logo]()
$95
This Orbitz deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:26 am
SFO
- MCI
1 stop6h 41m
Frontier
Deal found 3/8![Frontier logo]()
$95
This Super.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:05 pm
SFO
- STL
1 stop10h 43m
Frontier
Deal found 3/9![Frontier logo]()
$99
This Trip.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:38 pm
SFO
- STL
1 stop9h 52m
Frontier
Deal found 3/10![Frontier logo]()
$100
This Frontier deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/319:04 pm
SFO
- STL
1 stop10h 44m
Frontier
Deal found 3/9![Frontier logo]()
$101
This Expedia deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:00 am
SFO
- MCI
1 stop11h 58m
Frontier
Deal found 3/8![Frontier logo]()
$101
This Trip.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:24 pm
SFO
- STL
1 stop17h 21m
Frontier
Deal found 3/10![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:16 pm
SFO
- STL
2 stops32h 34m
Frontier
Deal found 3/10![Frontier logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:00 am
SFO
- MCI
1 stop28h 30m
Frontier
Deal found 3/6![Frontier logo]()
$109
Find flight deals from San Francisco to Missouri
Keep the following information in mind while searching for San Francisco to Missouri flight deals. Data was last updated March 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $278 (Kiwi.com) |
One-way from | $77 (Kiwi.com) |
Popular in | February |
Cheapest in | September |
Average price | $571 |
Good round-trip deal | $349 or less |
Good one-way deal | $254 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from San Francisco to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoSt. Louis
SFO - STL
SFOSTL
San Francisco
Wed 4/15
10:32 am-12:25 am
2 stops11h 53m
Lambert-St Louis
Fri 4/17
2:20 pm-11:37 pm
2 stops11h 17m
$305
San FranciscoKansas City
SFO - MCI
SFOMCI
San Francisco
Thu 8/20
9:53 am-6:15 pm
1 stop6h 22m
Kansas City
Sun 8/23
4:00 pm-9:35 pm
1 stop7h 35m
$309
San FranciscoKansas City
SFO - MCI
SFOMCI
San Francisco
Thu 8/13
1:00 pm-11:10 pm
1 stop8h 10m
Kansas City
Sat 8/15
6:40 am-12:30 pm
1 stop7h 50m
$309
San FranciscoColumbia
SFO - COU
SFOCOU
San Francisco
Fri 5/15
11:28 pm-9:46 am
1 stop8h 18m
Columbia Regional
Tue 5/19
4:28 pm-11:59 pm
1 stop9h 31m
$318
San FranciscoSpringfield
SFO - SGF
SFOSGF
San Francisco
Thu 4/2
11:35 pm-11:07 am
1 stop9h 32m
Springfield-Branson
Sat 5/2
4:00 pm-10:47 pm
1 stop8h 47m
$334
San FranciscoKansas City
SFO - MCI
SFOMCI
San Francisco
Sun 5/17
3:25 pm-12:25 am
1 stop7h 00m
Kansas City
Thu 5/21
5:55 am-12:35 pm
1 stop8h 40m
$349
Quickest round-trip
San FranciscoSt. Louis
SFO - STL
SFOSTL
San Francisco
Wed 4/1
12:00 pm-6:24 pm
Nonstop4h 24m
Lambert-St Louis
Thu 4/2
8:30 am-11:13 am
Nonstop4h 43m
$359
San FranciscoKansas City
SFO - MCI
SFOMCI
San Francisco
Tue 4/7
7:20 am-5:30 pm
2 stops8h 10m
Kansas City
Tue 4/14
12:25 pm-6:30 pm
2 stops8h 05m
$359
San FranciscoSt. Louis
SFO - STL
SFOSTL
San Francisco
Thu 4/9
11:20 pm-5:50 am
Nonstop4h 30m
Lambert-St Louis
Thu 4/16
8:15 pm-1:35 am
1 stop7h 20m
$369
San FranciscoKansas City
SFO - MCI
SFOMCI
San Francisco
Fri 7/17
6:05 am-3:05 pm
2 stops7h 00m
Kansas City
Sun 7/26
5:15 am-9:10 am
1 stop5h 55m
$369
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Francisco to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from San Francisco with our price prediction graph.
SFO-MCI
SFO-TBN
SFO-STL
SFO-COU
SFO-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Missouri
SFO-USMO
SFO-MCI
SFO-TBN
SFO-STL
SFO-COU
What is the cheapest month to book a flight from San Francisco to Missouri?
Currently, June is the cheapest month in which you can book a flight from San Francisco to Missouri (average of $114). Flying from San Francisco to Missouri in December is currently the most expensive (average of $245). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SFO to MO?
Find hourly flight availability from San Francisco to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 10, 2026.
When flying from San Francisco to Missouri, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 21% versus a flight in the morning.
Weekly flight availability from San Francisco to Missouri
Explore weekly flight availability from San Francisco to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 10, 2026.
The most flights from SFO to USMO are scheduled on a Monday (4 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 10, 2026.
Read through reviews of airlines operating flights from San Francisco to Missouri, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Francisco to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Francisco to Missouri by cabin class
Find flights from San Francisco to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Francisco and Missouri flights
Browse other San Francisco and Missouri flight options. Last updated on March 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Francisco to Missouri flights
Consider these flights traveling from San Francisco to Missouri.
Top 6 airlines flying from San Francisco to Missouri
Discover the top 6 airlines that operate flights from San Francisco to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$123 | Average$283 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$189 | Average$366 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$202 | Average$426 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$284 | Average$494 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$325 | Average$508 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$337 | Average$528 | FlexibilityNo cancel fee | On-time75% |