$73+ Cheap flights from Missouri to San Francisco (SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SFO
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to San Francisco
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Cheapest flights from Missouri to San FranciscoExplore the most affordable flight options available from Missouri to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Missouri to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:12 pm -
1 stop7h 14m
Thu 12/1711:37 am -
Nonstop3h 32m
Deal found 10/27![United Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:00 am -
Nonstop4h 02m
Fri 11/2711:33 am -
Nonstop3h 34m
Deal found 10/27![United Airlines logo]()
$311
This Cheapflightsfares deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:43 pm -
1 stop16h 34m
Fri 11/203:29 pm -
1 stop19h 05m
Deal found 10/26![Frontier logo]()
$312
This Frontier deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:32 pm -
2 stops15h 02m
Sat 12/126:30 am -
1 stop11h 05m
Deal found 10/28![Frontier logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:43 pm -
1 stop5h 37m
Mon 11/164:57 pm -
2 stops24h 50m
Deal found 10/26![Frontier logo]()
$316
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:43 pm -
1 stop16h 34m
Mon 11/1612:20 pm -
1 stop5h 27m
Deal found 10/27![Frontier logo]()
$318
This Expedia deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:43 pm -
1 stop5h 37m
Fri 11/136:02 am -
1 stop11h 45m
Deal found 10/28![Frontier logo]()
$320
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:55 am -
1 stop6h 50m
Wed 11/252:15 pm -
Nonstop3h 25m
Deal found 10/28![Southwest logo]()
$321
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:43 pm -
2 stops25h 49m
Fri 11/2010:59 pm -
2 stops18h 35m
Deal found 10/26![Frontier logo]()
$323
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:00 am -
Nonstop4h 05m
Thu 2/182:15 pm -
Nonstop3h 24m
Deal found 10/26![United Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/208:51 pm -
1 stop5h 44m
Sat 1/165:57 pm -
2 stops47h 39m
Deal found 10/28![Frontier logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:59 pm -
1 stop6h 21m
Fri 11/206:15 am -
1 stop26h 48m
Deal found 10/29![Frontier logo]()
$362
Best flights from Missouri to San FranciscoDiscover carefully curated flight deals from Missouri to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Missouri to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:00 am -
Nonstop4h 05m
Thu 12/1711:59 pm -
Nonstop3h 31m
Deal found 10/26![United Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/123:05 pm -
1 stop7h 05m
Mon 12/1411:15 am -
Nonstop3h 55m
Deal found 10/29![Southwest logo]()
$365
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/245:35 pm -
1 stop7h 51m
Fri 2/2612:47 am -
1 stop8h 26m
Deal found 10/25![American Airlines logo]()
$368
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/13:30 pm -
1 stop10h 45m
Tue 4/137:30 am -
1 stop8h 46m
Deal found 10/29![Delta logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:15 pm -
1 stop8h 14m
Sat 11/1411:47 pm -
1 stop9h 58m
Deal found 10/26![Multiple Airlines logo]()
$399
This Alaska Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/94:22 pm -
2 stops18h 30m
Sat 1/167:00 am -
1 stop6h 26m
Deal found 10/28![Alaska Airlines logo]()
$435
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:40 am -
1 stop8h 35m
Mon 12/712:20 pm -
Nonstop3h 51m
Deal found 10/29![United Airlines logo]()
$365
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:05 pm -
1 stop8h 27m
Fri 12/116:11 am -
1 stop9h 48m
Deal found 10/29![American Airlines logo]()
$368
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1910:35 am -
2 stops7h 25m
Thu 1/2111:55 am -
2 stops7h 55m
Deal found 10/29![Southwest logo]()
$387
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:05 pm -
Nonstop4h 33m
Mon 11/3012:15 am -
1 stop7h 30m
Deal found 10/26![United Airlines logo]()
$365
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:17 am -
1 stop8h 13m
Wed 12/911:12 am -
1 stop8h 27m
Deal found 10/26![American Airlines logo]()
$368
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/2510:35 am -
2 stops7h 25m
Thu 1/2811:55 am -
2 stops7h 55m
Deal found 10/25![Southwest logo]()
$387
This Alaska Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
2 stops11h 48m
Mon 11/237:20 am -
2 stops14h 39m
Deal found 10/28![Alaska Airlines logo]()
$441
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:13 pm -
1 stop7h 49m
Sun 12/2011:59 pm -
Nonstop3h 31m
Deal found 10/27![United Airlines logo]()
$365
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:43 am -
1 stop9h 42m
Sun 12/137:50 am -
1 stop6h 13m
Deal found 10/25![American Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:03 pm -
Nonstop4h 07m
Mon 11/3011:33 am -
Nonstop3h 34m
Deal found 10/27![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/198:45 am -
Nonstop4h 30m
Fri 1/2210:20 am -
Nonstop4h 00m
Deal found 10/25![Southwest logo]()
$437
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1412:15 pm -
1 stop12h 14m
Wed 11/1811:47 pm -
1 stop9h 58m
Deal found 10/29![Multiple Airlines logo]()
$569
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:11 pm -
1 stop7h 20m
Mon 11/166:01 am -
1 stop9h 51m
Deal found 10/29![American Airlines logo]()
$438
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/318:30 am -
1 stop8h 25m
Thu 1/710:20 am -
Nonstop4h 00m
Deal found 10/28![Southwest logo]()
$455
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:17 am -
Nonstop4h 38m
Sat 12/1212:20 pm -
Nonstop3h 51m
Deal found 10/25![United Airlines logo]()
$437
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/199:45 pm -
1 stop11h 45m
Wed 1/610:20 am -
Nonstop4h 00m
Deal found 10/28![Southwest logo]()
$461
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/315:05 am -
1 stop7h 35m
Thu 12/3111:00 pm -
Nonstop4h 06m
Deal found 10/29![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/126:43 am -
1 stop8h 46m
Mon 2/1512:15 pm -
1 stop7h 07m
Deal found 10/29![American Airlines logo]()
$483
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:20 pm -
1 stop7h 49m
Sat 11/284:51 pm -
Nonstop3h 24m
Deal found 10/26![United Airlines logo]()
$442
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:17 am -
Nonstop4h 38m
Wed 12/912:45 am -
1 stop7h 00m
Deal found 10/25![United Airlines logo]()
$447
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/249:35 am -
1 stop8h 00m
Thu 12/3111:00 pm -
Nonstop4h 06m
Deal found 10/26![United Airlines logo]()
$447
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/97:00 am -
Nonstop4h 27m
Sat 1/162:15 pm -
Nonstop3h 29m
Deal found 10/25![United Airlines logo]()
$477
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:00 am -
1 stop8h 10m
Wed 1/132:15 pm -
Nonstop3h 29m
Deal found 10/29![United Airlines logo]()
$487
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:00 am -
1 stop8h 15m
Mon 12/712:10 am -
1 stop8h 25m
Deal found 10/28![United Airlines logo]()
$488
Last-minute flights from Missouri to San FranciscoDiscover last-minute flight deals from Missouri to San Francisco. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to San Francisco. Data last updated October 30, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:43 pm -
1 stop16h 34m
Mon 11/1612:20 pm -
1 stop5h 27m
Deal found 10/27![Frontier logo]()
$318
This Expedia deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:43 pm -
1 stop5h 37m
Fri 11/136:02 am -
1 stop11h 45m
Deal found 10/28![Frontier logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:43 pm -
1 stop5h 37m
Mon 11/164:57 pm -
2 stops24h 50m
Deal found 10/26![Frontier logo]()
$316
This Expedia deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:52 pm -
2 stops20h 00m
Sat 11/1412:20 pm -
1 stop5h 27m
Deal found 10/29![Multiple Airlines logo]()
$332
This Trip.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:43 pm -
1 stop5h 37m
Sun 11/1511:06 am -
1 stop22h 49m
Deal found 10/26![Frontier logo]()
$324
This Cheapflightsfares deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:43 pm -
1 stop16h 34m
Fri 11/203:29 pm -
1 stop19h 05m
Deal found 10/26![Frontier logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:59 pm -
1 stop6h 21m
Fri 11/206:15 am -
1 stop26h 48m
Deal found 10/29![Frontier logo]()
$362
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:43 pm -
2 stops25h 49m
Fri 11/2010:59 pm -
2 stops18h 35m
Deal found 10/26![Frontier logo]()
$323
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:55 am -
1 stop6h 50m
Wed 11/252:15 pm -
Nonstop3h 25m
Deal found 10/28![Southwest logo]()
$321
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:00 am -
Nonstop4h 02m
Fri 11/274:51 pm -
Nonstop3h 24m
Deal found 10/27![United Airlines logo]()
$331
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:04 pm -
1 stop20h 40m
Sun 11/299:23 pm -
1 stop11h 40m
Deal found 10/27![Frontier logo]()
$364
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:00 am -
Nonstop4h 02m
Fri 11/2711:33 am -
Nonstop3h 34m
Deal found 10/27![United Airlines logo]()
$311
One-way flights from Missouri to San FranciscoSearch for one-way flight options from Missouri to San Francisco. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Missouri to San Francisco. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:54 pm -
2 stops26h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Frontier logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:40 am -
1 stop14h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Frontier logo]()
$79
This WAYA deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:54 pm -
1 stop15h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Frontier logo]()
$80
This Super.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:54 pm -
1 stop15h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Frontier logo]()
$87
This Expedia deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/203:04 pm -
1 stop20h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Frontier logo]()
$89
This Super.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:32 pm -
1 stop6h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Frontier logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:20 pm -
1 stop8h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Frontier logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:32 pm -
2 stops25h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Frontier logo]()
$96
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/214:21 pm -
1 stop6h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Frontier logo]()
$101
This Booking.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:43 pm -
2 stops25h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Frontier logo]()
$101
This Cheapflightsfares deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/157:02 pm -
1 stop7h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/44:21 pm -
1 stop10h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Frontier logo]()
$104
Find flight deals from Missouri to San Francisco
Keep the following information in mind while searching for Missouri to San Francisco flight deals. Data was last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $234 (Kiwi.com) |
One-way from | $73 (Kiwi.com) |
Popular in | November |
Cheapest in | January |
Average price | $516 |
Good round-trip deal | $471 or less |
Good one-way deal | $231 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Missouri to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSan Francisco
STL Lambert-St Louis - SFO San Francisco
STLSFO
Lambert-St Louis
Mon 11/9
7:59 pm-12:20 am
1 stop6h 21m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$102
Kansas CitySan Francisco
MCI Kansas City - SFO San Francisco
MCISFO
Kansas City
Fri 1/22
4:22 pm-8:52 am
2 stops18h 30m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$133
St. LouisSan Francisco
STL Lambert-St Louis - SFO San Francisco
STLSFO
Lambert-St Louis
Thu 12/31
5:37 pm-7:04 am
1 stop15h 27m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$164
St. LouisSan Francisco
STL Lambert-St Louis - SFO San Francisco
STLSFO
Lambert-St Louis
Thu 11/26
7:05 pm-9:38 pm
Nonstop4h 33m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$178
St. LouisSan Francisco
STL Lambert-St Louis - SFO San Francisco
STLSFO
Lambert-St Louis
Fri 12/11
8:17 am-10:55 am
Nonstop4h 38m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$198
Kansas CitySan Francisco
MCI Kansas City - SFO San Francisco
MCISFO
Kansas City
Sun 12/6
7:00 am-9:05 am
Nonstop4h 05m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$199
St. LouisSan Francisco
STL Lambert-St Louis - SFO San Francisco
STLSFO
Lambert-St Louis
Wed 12/30
7:46 pm-12:23 am
1 stop6h 37m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$209
St. LouisSan Francisco
STL Lambert-St Louis - SFO San Francisco
STLSFO
Lambert-St Louis
Fri 2/26
5:10 pm-7:45 pm
Nonstop4h 35m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$219
St. LouisSan Francisco
STL Lambert-St Louis - SFO San Francisco
STLSFO
Lambert-St Louis
Mon 2/15
5:10 pm-7:45 pm
Nonstop4h 35m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$219
St. LouisSan Francisco
STL Lambert-St Louis - SFO San Francisco
STLSFO
Lambert-St Louis
Tue 1/5
8:25 am-10:50 am
Nonstop4h 25m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$219
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Missouri with our price prediction graph.
MCI-SFO
STL-SFO
SGF-SFO
COU-SFO
TBN-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to San Francisco
USMO-SFO
MCI-SFO
STL-SFO
SGF-SFO
COU-SFO
What is the cheapest month to book a flight from Missouri to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Missouri to San Francisco (average of $380). Flying from Missouri to San Francisco in November is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to SFO?
Find hourly flight availability from Missouri to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2026.
It’s typically best to fly out from Missouri to San Francisco at noon. Doing so could potentially save you 36% on the flight price compared to flying in the evening, which is usually more expensive.
How much does it cost to fly round-trip from Missouri to San Francisco?
Airfare is below average for this route at the moment.
Missouri to San Francisco flights typically cost between $425 and $626 in November.The cheapest round-trip price found within the last 5 days was $362 on Frontier (Nov 16-Nov 20).
How far ahead should I book a flight from Missouri to San Francisco?
Booking 86 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from Missouri to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Hayward
Emeryville
Newark
Burlingame
Rancho Cordova
Vallejo
Cupertino
Fairfield
Redwood City
Manteca
San Bruno
San Carlos
San Ramon
Turlock
Davis
Morgan Hill
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to San Francisco by cabin class
Find flights from Missouri to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and San Francisco flights
Browse other Missouri and San Francisco flight options. Last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Missouri to San Francisco flights
Consider these flights traveling from Missouri to San Francisco.
Top 6 airlines flying from Missouri to San Francisco
Discover the top 6 airlines that operate flights from Missouri to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$146 | Average$297 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$236 | Average$406 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$322 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$250 | Average$475 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$284 | Average$491 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$289 | Average$488 | FlexibilityNo cancel fee | On-time69% |