$94+ Cheap flights from Missouri to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SFO
Sep 1 — Sep 81
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to San Francisco
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Cheapest flights from Missouri to San FranciscoExplore the most affordable flight options available from Missouri to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2026.
Explore the most affordable flight options available from Missouri to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1412:52 pm
SGF
- SFO
1 stop21h 22m
Multiple Airlines
Fri 9/181:10 pm
SFO
- SGF
1 stop20h 52m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$303
This Expedia deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/182:17 pm
MCI
- SFO
2 stops10h 51m
Multiple Airlines
Thu 8/2011:00 am
SFO
- MCI
1 stop27h 02m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$323
This Super.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:32 pm
MCI
- SFO
1 stop5h 38m
Frontier
Thu 8/206:00 am
SFO
- MCI
1 stop5h 20m
Frontier
Deal found 8/1![Frontier logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:17 pm
MCI
- SFO
2 stops11h 34m
Frontier
Fri 10/307:17 pm
SFO
- MCI
1 stop16h 05m
Frontier
Deal found 7/28![Frontier logo]()
$327
This Super.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/134:32 pm
MCI
- SFO
1 stop5h 38m
Frontier
Fri 8/146:04 pm
SFO
- MCI
1 stop16h 56m
Frontier
Deal found 7/28![Frontier logo]()
$328
This Frontier deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/111:50 pm
MCI
- SFO
1 stop12h 01m
Frontier
Sun 10/186:00 am
SFO
- MCI
1 stop5h 22m
Frontier
Deal found 8/1![Frontier logo]()
$329
This Expedia deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:48 pm
MCI
- SFO
2 stops10h 24m
Multiple Airlines
Thu 9/38:56 pm
SFO
- MCI
1 stop17h 06m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$330
This Super.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:32 pm
MCI
- SFO
1 stop5h 38m
Frontier
Sun 8/164:47 pm
SFO
- MCI
1 stop18h 13m
Frontier
Deal found 8/1![Frontier logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:17 pm
MCI
- SFO
1 stop11h 58m
Frontier
Fri 10/309:00 pm
SFO
- MCI
2 stops14h 22m
Frontier
Deal found 7/28![Frontier logo]()
$332
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:30 am
MCI
- SFO
1 stop6h 37m
American Airlines
Mon 8/3110:53 pm
SFO
- MCI
1 stop7h 47m
American Airlines
Deal found 7/30![American Airlines logo]()
$333
This Super.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/91:45 pm
MCI
- SFO
1 stop6h 24m
Frontier
Mon 8/106:04 pm
SFO
- MCI
1 stop16h 56m
Frontier
Deal found 7/28![Frontier logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/182:17 pm
MCI
- SFO
1 stop11h 58m
Multiple Airlines
Thu 10/298:20 am
SFO
- MCI
2 stops13h 39m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$335
Best flights from Missouri to San FranciscoDiscover carefully curated flight deals from Missouri to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 2, 2026.
Discover carefully curated flight deals from Missouri to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 2, 2026.
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:29 pm
MCI
- SFO
Nonstop3h 54m
United Airlines
Tue 8/258:48 am
SFO
- MCI
Nonstop3h 45m
United Airlines
Deal found 7/28![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/222:05 pm
MCI
- SFO
2 stops7h 30m
Southwest
Tue 8/255:50 am
SFO
- MCI
2 stops7h 35m
Southwest
Deal found 7/28![Southwest logo]()
$343
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:46 pm
STL
- SFO
1 stop8h 11m
Delta
Sat 9/198:59 pm
SFO
- STL
2 stops9h 41m
Delta
Deal found 8/1![Delta logo]()
$373
This Alaska Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:56 pm
STL
- SFO
1 stop15h 41m
Alaska Airlines
Tue 8/259:13 pm
SFO
- STL
2 stops17h 57m
Alaska Airlines
Deal found 7/31![Alaska Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:59 am
COU
- SFO
1 stop9h 18m
American Airlines
Fri 10/166:00 am
SFO
- COU
1 stop9h 54m
American Airlines
Deal found 7/28![American Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:15 am
COU
- SFO
1 stop7h 10m
United Airlines
Mon 9/712:35 am
SFO
- COU
1 stop8h 04m
United Airlines
Deal found 8/1![United Airlines logo]()
$348
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:25 am
STL
- SFO
1 stop6h 00m
Southwest
Thu 10/11:05 pm
SFO
- STL
Nonstop3h 45m
Southwest
Deal found 7/29![Southwest logo]()
$363
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:32 pm
STL
- SFO
2 stops11h 18m
Delta
Wed 9/210:00 pm
SFO
- STL
1 stop9h 20m
Delta
Deal found 7/28![Delta logo]()
$375
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:24 pm
MCI
- SFO
1 stop7h 27m
United Airlines
Sat 10/1710:53 am
SFO
- MCI
Nonstop3h 31m
United Airlines
Deal found 7/31![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:08 am
STL
- SFO
Nonstop4h 22m
United Airlines
Thu 10/112:45 pm
SFO
- STL
Nonstop3h 58m
United Airlines
Deal found 7/30![United Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:20 pm
STL
- SFO
2 stops8h 15m
Southwest
Mon 9/216:00 am
SFO
- STL
2 stops9h 55m
Southwest
Deal found 7/31![Southwest logo]()
$423
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:05 am
COU
- SFO
1 stop7h 19m
American Airlines
Tue 12/299:12 am
SFO
- COU
1 stop6h 42m
American Airlines
Deal found 7/31![American Airlines logo]()
$479
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:13 pm
MCI
- SFO
1 stop7h 42m
United Airlines
Mon 9/75:00 am
SFO
- MCI
1 stop5h 37m
United Airlines
Deal found 8/1![United Airlines logo]()
$361
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:40 am
MCI
- SFO
2 stops8h 15m
Southwest
Wed 8/265:50 am
SFO
- MCI
2 stops7h 35m
Southwest
Deal found 7/28![Southwest logo]()
$424
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:05 pm
COU
- SFO
1 stop8h 27m
American Airlines
Tue 12/299:12 am
SFO
- COU
1 stop6h 42m
American Airlines
Deal found 8/1![American Airlines logo]()
$479
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:15 am
STL
- SFO
1 stop7h 29m
United Airlines
Mon 9/2812:45 pm
SFO
- STL
Nonstop3h 58m
United Airlines
Deal found 7/29![United Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:17 pm
COU
- SFO
1 stop7h 01m
American Airlines
Sun 9/136:36 am
SFO
- COU
1 stop9h 20m
American Airlines
Deal found 7/28![American Airlines logo]()
$483
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:25 am
STL
- SFO
1 stop6h 00m
Southwest
Sun 9/1312:00 pm
SFO
- STL
Nonstop3h 50m
Southwest
Deal found 7/28![Southwest logo]()
$454
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:13 pm
MCI
- SFO
1 stop7h 42m
United Airlines
Mon 8/248:48 am
SFO
- MCI
Nonstop3h 45m
United Airlines
Deal found 8/1![United Airlines logo]()
$380
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:35 am
STL
- SFO
Nonstop4h 22m
United Airlines
Sat 9/195:00 am
SFO
- STL
1 stop8h 38m
United Airlines
Deal found 8/1![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:13 pm
MCI
- SFO
1 stop7h 42m
United Airlines
Sun 8/168:48 am
SFO
- MCI
Nonstop3h 45m
United Airlines
Deal found 7/28![United Airlines logo]()
$415
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:29 pm
MCI
- SFO
Nonstop3h 54m
United Airlines
Tue 9/158:48 am
SFO
- MCI
Nonstop3h 45m
United Airlines
Deal found 7/31![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:38 am
MCI
- SFO
Nonstop3h 52m
United Airlines
Mon 10/54:15 pm
SFO
- MCI
Nonstop3h 37m
United Airlines
Deal found 8/1![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/193:29 pm
MCI
- SFO
Nonstop3h 54m
United Airlines
Sat 9/2610:53 am
SFO
- MCI
Nonstop3h 34m
United Airlines
Deal found 8/1![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:29 pm
MCI
- SFO
Nonstop3h 54m
United Airlines
Thu 8/278:48 am
SFO
- MCI
Nonstop3h 45m
United Airlines
Deal found 7/31![United Airlines logo]()
$443
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:12 pm
COU
- SFO
1 stop9h 47m
United Airlines
Wed 9/910:43 am
SFO
- COU
1 stop7h 56m
United Airlines
Deal found 8/1![United Airlines logo]()
$448
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:15 am
COU
- SFO
1 stop7h 10m
United Airlines
Sun 9/2712:35 am
SFO
- COU
1 stop8h 04m
United Airlines
Deal found 7/31![United Airlines logo]()
$448
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:42 am
STL
- SFO
Nonstop4h 22m
United Airlines
Sun 9/1312:00 pm
SFO
- STL
Nonstop3h 59m
United Airlines
Deal found 7/31![United Airlines logo]()
$448
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:30 pm
JLN
- SFO
1 stop5h 53m
United Airlines
Sat 10/2412:55 am
SFO
- JLN
1 stop9h 42m
United Airlines
Deal found 8/1![United Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:15 pm
SGF
- SFO
1 stop8h 21m
United Airlines
Tue 12/85:00 am
SFO
- SGF
1 stop9h 03m
United Airlines
Deal found 8/1![United Airlines logo]()
$459
Last-minute flights from Missouri to San FranciscoDiscover last-minute flight deals from Missouri to San Francisco. Data last updated August 2, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to San Francisco. Data last updated August 2, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/41:45 pm
MCI
- SFO
1 stop12h 38m
Frontier
Tue 8/1112:38 pm
SFO
- MCI
1 stop22h 22m
Frontier
Deal found 7/28![Frontier logo]()
$340
This Super.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/91:45 pm
MCI
- SFO
1 stop6h 24m
Frontier
Mon 8/106:04 pm
SFO
- MCI
1 stop16h 56m
Frontier
Deal found 7/28![Frontier logo]()
$334
This Super.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/134:32 pm
MCI
- SFO
1 stop5h 38m
Frontier
Fri 8/146:04 pm
SFO
- MCI
1 stop16h 56m
Frontier
Deal found 7/28![Frontier logo]()
$328
This Super.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:32 pm
MCI
- SFO
1 stop5h 38m
Frontier
Thu 8/206:00 am
SFO
- MCI
1 stop5h 20m
Frontier
Deal found 8/1![Frontier logo]()
$325
This Super.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:32 pm
MCI
- SFO
1 stop5h 38m
Frontier
Sun 8/164:47 pm
SFO
- MCI
1 stop18h 13m
Frontier
Deal found 8/1![Frontier logo]()
$331
This Expedia deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/182:17 pm
MCI
- SFO
2 stops10h 51m
Multiple Airlines
Thu 8/2011:00 am
SFO
- MCI
1 stop27h 02m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$323
This Alaska Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:48 pm
MCI
- SFO
1 stop7h 06m
Alaska Airlines
Thu 8/277:00 am
SFO
- MCI
1 stop14h 59m
Alaska Airlines
Deal found 7/31![Alaska Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:13 pm
MCI
- SFO
1 stop7h 42m
United Airlines
Tue 8/258:48 am
SFO
- MCI
Nonstop3h 45m
United Airlines
Deal found 7/28![United Airlines logo]()
$332
This Expedia deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/234:47 pm
MCI
- SFO
1 stop25h 49m
Multiple Airlines
Wed 8/268:23 am
SFO
- MCI
2 stops13h 36m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$338
This Expedia deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:48 pm
MCI
- SFO
2 stops10h 24m
Multiple Airlines
Thu 9/38:56 pm
SFO
- MCI
1 stop17h 06m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:30 am
MCI
- SFO
1 stop6h 37m
American Airlines
Mon 8/3110:53 pm
SFO
- MCI
1 stop7h 47m
American Airlines
Deal found 7/30![American Airlines logo]()
$333
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:29 pm
MCI
- SFO
Nonstop3h 54m
United Airlines
Wed 9/912:45 am
SFO
- MCI
1 stop7h 21m
United Airlines
Deal found 7/28![United Airlines logo]()
$336
One-way flights from Missouri to San FranciscoSearch for one-way flight options from Missouri to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 2, 2026.
Search for one-way flight options from Missouri to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:10 pm
STL
- SFO
2 stops27h 17m
Frontier
Deal found 7/28![Frontier logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:10 pm
STL
- SFO
2 stops27h 17m
Frontier
Deal found 7/31![Frontier logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/237:58 pm
STL
- SFO
2 stops26h 42m
Frontier
Deal found 7/29![Frontier logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:10 pm
STL
- SFO
2 stops38h 13m
Frontier
Deal found 7/31![Frontier logo]()
$116
This Alaska Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:29 am
STL
- SFO
2 stops12h 53m
Alaska Airlines
Deal found 7/29![Alaska Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:10 pm
STL
- SFO
2 stops20h 19m
Frontier
Deal found 7/31![Frontier logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:10 pm
STL
- SFO
2 stops27h 08m
Frontier
Deal found 7/27![Frontier logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:10 pm
STL
- SFO
2 stops40h 12m
Frontier
Deal found 7/28![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:58 pm
STL
- SFO
2 stops26h 48m
Frontier
Deal found 7/29![Frontier logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:58 pm
STL
- SFO
2 stops26h 42m
Frontier
Deal found 7/27![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:49 pm
SGF
- SFO
1 stop22h 35m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/301:18 pm
SGF
- SFO
1 stop28h 38m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$166
Find flight deals from Missouri to San Francisco
Keep the following information in mind while searching for Missouri to San Francisco flight deals. Data was last updated August 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $303 (Kiwi.com) |
One-way from | $94 (Kiwi.com) |
Popular in | June |
Cheapest in | February |
Average price | $349 |
Good round-trip deal | $439 or less |
Good one-way deal | $209 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2026.
Use the filters below to find and compare flights from Missouri to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Sat 8/22
3:29 pm-5:23 pm
Nonstop3h 54m
San Francisco
Tue 8/25
8:48 am-2:33 pm
Nonstop3h 45m
$339
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Sat 8/22
2:05 pm-7:35 pm
2 stops7h 30m
San Francisco
Tue 8/25
5:50 am-3:25 pm
2 stops7h 35m
$343
ColumbiaSan Francisco
COU - SFO
COUSFO
Columbia Regional
Thu 9/3
6:15 am-11:25 am
1 stop7h 10m
San Francisco
Mon 9/7
12:35 am-10:39 am
1 stop8h 04m
$348
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Thu 10/15
5:24 pm-10:51 pm
1 stop7h 27m
San Francisco
Sat 10/17
10:53 am-4:24 pm
Nonstop3h 31m
$349
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Tue 9/29
7:08 am-9:30 am
Nonstop4h 22m
San Francisco
Thu 10/1
12:45 pm-6:43 pm
Nonstop3h 58m
$357
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Sat 9/5
5:13 pm-10:55 pm
1 stop7h 42m
San Francisco
Mon 9/7
5:00 am-12:37 pm
1 stop5h 37m
$361
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Mon 9/28
6:25 am-10:25 am
1 stop6h 00m
San Francisco
Thu 10/1
1:05 pm-6:50 pm
Nonstop3h 45m
$363
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Thu 9/24
6:15 am-11:44 am
1 stop7h 29m
San Francisco
Mon 9/28
12:45 pm-6:43 pm
Nonstop3h 58m
$367
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Wed 9/9
5:46 pm-11:57 pm
1 stop8h 11m
San Francisco
Sat 9/19
8:59 pm-8:40 am
2 stops9h 41m
$373
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Fri 8/28
2:32 pm-11:50 pm
2 stops11h 18m
San Francisco
Wed 9/2
10:00 pm-9:20 am
1 stop9h 20m
$375
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Missouri with our price prediction graph.
STL-SFO
SGF-SFO
MCI-SFO
COU-SFO
JLN-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to San Francisco
USMO-SFO
STL-SFO
SGF-SFO
MCI-SFO
COU-SFO
What is the cheapest month to book a flight from Missouri to San Francisco?
Currently, October is the cheapest month in which you can book a flight from Missouri to San Francisco (average of $382). Flying from Missouri to San Francisco in March is currently the most expensive (average of $503). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to SFO?
Find hourly flight availability from Missouri to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 2, 2026.
It’s typically best to fly out from Missouri to San Francisco in the morning. Doing so could potentially save you 24% on the flight price compared to flying in the afternoon, which is usually more expensive.
Weekly flight availability from Missouri to San Francisco
Explore weekly flight availability from Missouri to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 2, 2026.
The most flights from USMO to SFO are scheduled on a Monday (5 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Missouri to San Francisco?
Airfare is typical for this route at the moment.
Missouri to San Francisco flights typically cost between $310 and $552 in September.The cheapest round-trip price found within the last 5 days was $349 on Delta (Sep 30-Oct 3).
How far ahead should I book a flight from Missouri to San Francisco?
Booking 61 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from Missouri to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Fairfield
Emeryville
Roseville
Burlingame
Rancho Cordova
San Bruno
Cupertino
Newark
Hayward
San Ramon
Redwood City
San Carlos
Turlock
Vallejo
San Lorenzo
Davis
Vacaville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to San Francisco
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Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to San Francisco by cabin class
Find flights from Missouri to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and San Francisco flights
Browse other Missouri and San Francisco flight options. Last updated on August 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 2, 2026.
Missouri to San Francisco flights
Consider these flights traveling from Missouri to San Francisco.
Top 6 airlines flying from Missouri to San Francisco
Discover the top 6 airlines that operate flights from Missouri to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$144 | Average$265 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$182 | Average$458 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$216 | Average$376 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$322 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$278 | Average$459 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$284 | Average$483 | FlexibilityNo cancel fee | On-time63% |