$99+ Cheap flights from Missouri to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/11. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — SFO
Jul 15 — Jul 221
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to San Francisco with Cheapflights
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Cheapest flights from Missouri to San FranciscoExplore the most affordable flight options available from Missouri to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 15, 2026.
Explore the most affordable flight options available from Missouri to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:03 pm
STL
- SFO
1 stop17h 27m
Frontier
Tue 7/1410:23 pm
SFO
- STL
2 stops41h 52m
Frontier
Deal found 6/11![Frontier logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:08 pm
STL
- SFO
1 stop6h 15m
Frontier
Wed 7/159:00 pm
SFO
- STL
1 stop19h 15m
Frontier
Deal found 6/13![Frontier logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:10 pm
STL
- SFO
1 stop17h 20m
Frontier
Thu 7/239:00 pm
SFO
- STL
1 stop19h 15m
Frontier
Deal found 6/11![Frontier logo]()
$310
This CheapOair deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/67:10 pm
STL
- SFO
1 stop26h 42m
Frontier
Wed 7/84:30 pm
SFO
- STL
1 stop23h 45m
Frontier
Deal found 6/11![Frontier logo]()
$313
This Frontier deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:08 pm
STL
- SFO
1 stop6h 10m
Frontier
Mon 8/176:00 am
SFO
- STL
1 stop11h 23m
Frontier
Deal found 6/15![Frontier logo]()
$314
This Orbitz deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:08 pm
STL
- SFO
1 stop22h 44m
Frontier
Tue 8/44:30 pm
SFO
- STL
1 stop23h 35m
Frontier
Deal found 6/11![Frontier logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:38 pm
STL
- SFO
1 stop6h 49m
Frontier
Tue 7/79:00 pm
SFO
- STL
1 stop19h 05m
Frontier
Deal found 6/10![Frontier logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:03 pm
STL
- SFO
1 stop15h 45m
Frontier
Fri 7/318:23 pm
SFO
- STL
2 stops19h 52m
Frontier
Deal found 6/10![Frontier logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:41 pm
STL
- SFO
1 stop9h 18m
Frontier
Tue 7/218:23 pm
SFO
- STL
2 stops19h 42m
Frontier
Deal found 6/11![Frontier logo]()
$318
This Frontier deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:08 pm
STL
- SFO
1 stop6h 15m
Frontier
Tue 8/116:00 am
SFO
- STL
1 stop11h 23m
Frontier
Deal found 6/10![Frontier logo]()
$319
This Frontier deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:33 pm
STL
- SFO
1 stop9h 24m
Frontier
Wed 9/26:00 am
SFO
- STL
1 stop11h 23m
Frontier
Deal found 6/12![Frontier logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:38 pm
STL
- SFO
1 stop6h 49m
Frontier
Tue 7/79:00 pm
SFO
- STL
1 stop19h 05m
Frontier
Deal found 6/10![Frontier logo]()
$322
Best flights from Missouri to San FranciscoDiscover carefully curated flight deals from Missouri to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 15, 2026.
Discover carefully curated flight deals from Missouri to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 15, 2026.
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1512:23 pm
MCI
- SFO
1 stop6h 52m
Delta
Mon 10/125:00 pm
SFO
- MCI
1 stop5h 21m
Delta
Deal found 6/14![Delta logo]()
$337
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:26 pm
COU
- SFO
1 stop7h 17m
American Airlines
Sat 7/115:29 am
SFO
- COU
1 stop9h 20m
American Airlines
Deal found 6/12![American Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:10 pm
MCI
- SFO
1 stop5h 46m
United Airlines
Fri 8/148:48 am
SFO
- MCI
Nonstop3h 45m
United Airlines
Deal found 6/13![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:40 am
MCI
- SFO
2 stops8h 15m
Southwest
Tue 9/2911:15 am
SFO
- MCI
2 stops9h 55m
Southwest
Deal found 6/11![Southwest logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:51 pm
SGF
- SFO
1 stop7h 01m
Multiple Airlines
Thu 7/169:00 pm
SFO
- SGF
1 stop13h 31m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$512
This Alaska Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:16 am
STL
- SFO
2 stops9h 06m
Alaska Airlines
Wed 9/28:23 am
SFO
- STL
1 stop6h 47m
Alaska Airlines
Deal found 6/13![Alaska Airlines logo]()
$515
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:00 pm
MCI
- SFO
Nonstop4h 03m
United Airlines
Sat 11/75:20 am
SFO
- MCI
1 stop7h 11m
United Airlines
Deal found 6/14![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:30 pm
SGF
- SFO
1 stop9h 21m
Delta
Tue 11/37:30 am
SFO
- SGF
1 stop8h 40m
Delta
Deal found 6/13![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:40 pm
SGF
- SFO
1 stop7h 03m
American Airlines
Mon 7/1311:07 pm
SFO
- SGF
1 stop8h 56m
American Airlines
Deal found 6/15![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:42 am
MCI
- SFO
1 stop7h 44m
Delta
Fri 10/235:00 pm
SFO
- MCI
1 stop5h 21m
Delta
Deal found 6/12![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:25 am
STL
- SFO
Nonstop4h 10m
Southwest
Wed 9/2311:50 am
SFO
- STL
Nonstop3h 50m
Southwest
Deal found 6/11![Southwest logo]()
$409
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:59 pm
MCI
- SFO
Nonstop3h 51m
United Airlines
Mon 8/1011:30 pm
SFO
- MCI
1 stop7h 28m
United Airlines
Deal found 6/15![United Airlines logo]()
$373
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:39 pm
COU
- SFO
1 stop7h 09m
American Airlines
Sun 6/2812:26 am
SFO
- COU
1 stop8h 48m
American Airlines
Deal found 6/12![American Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:59 pm
MCI
- SFO
Nonstop3h 51m
United Airlines
Mon 7/610:38 pm
SFO
- MCI
1 stop8h 04m
United Airlines
Deal found 6/15![United Airlines logo]()
$374
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1811:55 am
STL
- SFO
Nonstop4h 15m
Southwest
Wed 10/2811:40 am
SFO
- STL
Nonstop3h 50m
Southwest
Deal found 6/10![Southwest logo]()
$422
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:37 pm
SGF
- SFO
1 stop7h 53m
United Airlines
Sun 8/237:05 am
SFO
- SGF
1 stop7h 06m
United Airlines
Deal found 6/11![United Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:25 am
STL
- SFO
1 stop6h 00m
Southwest
Tue 9/1511:50 am
SFO
- STL
Nonstop3h 50m
Southwest
Deal found 6/12![Southwest logo]()
$460
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:39 pm
SGF
- SFO
1 stop8h 18m
Delta
Fri 10/166:00 am
SFO
- SGF
1 stop10h 10m
Delta
Deal found 6/15![Delta logo]()
$479
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:19 pm
COU
- SFO
1 stop7h 09m
American Airlines
Sat 7/1111:07 pm
SFO
- COU
1 stop8h 54m
American Airlines
Deal found 6/13![American Airlines logo]()
$491
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:25 am
STL
- SFO
Nonstop4h 15m
Southwest
Tue 10/66:50 am
SFO
- STL
1 stop5h 30m
Southwest
Deal found 6/12![Southwest logo]()
$460
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:29 pm
MCI
- SFO
Nonstop3h 54m
United Airlines
Wed 10/72:20 pm
SFO
- MCI
1 stop7h 24m
United Airlines
Deal found 6/12![United Airlines logo]()
$423
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:42 am
STL
- SFO
Nonstop4h 22m
United Airlines
Tue 9/292:20 pm
SFO
- STL
1 stop7h 24m
United Airlines
Deal found 6/11![United Airlines logo]()
$425
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:15 pm
STL
- SFO
1 stop7h 05m
Southwest
Mon 11/91:05 pm
SFO
- STL
Nonstop3h 50m
Southwest
Deal found 6/14![Southwest logo]()
$481
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:00 am
MCI
- SFO
Nonstop4h 03m
United Airlines
Sun 11/1511:27 am
SFO
- MCI
Nonstop3h 22m
United Airlines
Deal found 6/14![United Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:55 am
COU
- SFO
1 stop9h 49m
United Airlines
Tue 9/111:30 pm
SFO
- COU
1 stop8h 46m
United Airlines
Deal found 6/11![United Airlines logo]()
$438
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:29 pm
MCI
- SFO
Nonstop3h 54m
United Airlines
Wed 9/1612:45 am
SFO
- MCI
1 stop7h 21m
United Airlines
Deal found 6/10![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:59 pm
MCI
- SFO
Nonstop3h 51m
United Airlines
Sat 7/1111:30 pm
SFO
- MCI
1 stop7h 12m
United Airlines
Deal found 6/11![United Airlines logo]()
$440
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:53 pm
JLN
- SFO
1 stop7h 45m
United Airlines
Mon 8/314:18 pm
SFO
- JLN
1 stop5h 26m
United Airlines
Deal found 6/14![United Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:35 am
SGF
- SFO
1 stop7h 43m
United Airlines
Tue 11/177:00 am
SFO
- SGF
1 stop7h 03m
United Airlines
Deal found 6/14![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:25 am
SGF
- SFO
1 stop7h 49m
United Airlines
Sat 9/510:35 pm
SFO
- SGF
1 stop10h 13m
United Airlines
Deal found 6/10![United Airlines logo]()
$449
Last-minute flights from Missouri to San FranciscoDiscover last-minute flight deals from Missouri to San Francisco. Data last updated June 15, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to San Francisco. Data last updated June 15, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:38 pm
STL
- SFO
1 stop6h 49m
Frontier
Tue 7/79:00 pm
SFO
- STL
1 stop19h 05m
Frontier
Deal found 6/10![Frontier logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:38 pm
STL
- SFO
1 stop6h 49m
Frontier
Tue 7/79:00 pm
SFO
- STL
1 stop19h 05m
Frontier
Deal found 6/10![Frontier logo]()
$316
This CheapOair deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/67:10 pm
STL
- SFO
1 stop26h 42m
Frontier
Wed 7/84:30 pm
SFO
- STL
1 stop23h 45m
Frontier
Deal found 6/11![Frontier logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:03 pm
STL
- SFO
1 stop17h 27m
Frontier
Tue 7/1410:23 pm
SFO
- STL
2 stops41h 52m
Frontier
Deal found 6/11![Frontier logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:08 pm
STL
- SFO
1 stop6h 15m
Frontier
Wed 7/159:00 pm
SFO
- STL
1 stop19h 15m
Frontier
Deal found 6/13![Frontier logo]()
$308
This Frontier deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:08 pm
STL
- SFO
1 stop6h 15m
Frontier
Wed 7/156:00 am
SFO
- STL
1 stop11h 23m
Frontier
Deal found 6/14![Frontier logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:41 pm
STL
- SFO
1 stop9h 18m
Frontier
Tue 7/218:23 pm
SFO
- STL
2 stops19h 42m
Frontier
Deal found 6/11![Frontier logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:08 pm
STL
- SFO
1 stop6h 15m
Frontier
Tue 7/218:23 pm
SFO
- STL
2 stops19h 42m
Frontier
Deal found 6/10![Frontier logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:10 pm
STL
- SFO
1 stop17h 20m
Frontier
Thu 7/239:00 pm
SFO
- STL
1 stop19h 15m
Frontier
Deal found 6/11![Frontier logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/211:45 pm
MCI
- SFO
1 stop12h 38m
Frontier
Tue 7/2810:23 pm
SFO
- MCI
2 stops39h 24m
Frontier
Deal found 6/14![Frontier logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:03 pm
STL
- SFO
1 stop15h 45m
Frontier
Fri 7/318:23 pm
SFO
- STL
2 stops19h 52m
Frontier
Deal found 6/10![Frontier logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:10 pm
STL
- SFO
1 stop15h 38m
Frontier
Mon 8/310:23 pm
SFO
- STL
2 stops19h 00m
Frontier
Deal found 6/14![Frontier logo]()
$323
One-way flights from Missouri to San FranciscoSearch for one-way flight options from Missouri to San Francisco. Find affordable one-way fares based on user searches. Data last updated June 15, 2026.
Search for one-way flight options from Missouri to San Francisco. Find affordable one-way fares based on user searches. Data last updated June 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:03 pm
STL
- SFO
1 stop17h 22m
Frontier
Deal found 6/11![Frontier logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:10 pm
STL
- SFO
1 stop17h 20m
Frontier
Deal found 6/12![Frontier logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:32 pm
MCI
- SFO
1 stop19h 55m
Frontier
Deal found 6/10![Frontier logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:10 pm
STL
- SFO
1 stop22h 15m
Frontier
Deal found 6/14![Frontier logo]()
$117
This Trip.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:10 pm
STL
- SFO
1 stop26h 42m
Frontier
Deal found 6/13![Frontier logo]()
$118
This Super.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:08 pm
STL
- SFO
1 stop6h 15m
Frontier
Deal found 6/11![Frontier logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/34:32 pm
MCI
- SFO
1 stop19h 58m
Frontier
Deal found 6/14![Frontier logo]()
$120
This Priceline deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:08 pm
STL
- SFO
1 stop6h 15m
Frontier
Deal found 6/11![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:33 pm
STL
- SFO
1 stop28h 07m
Frontier
Deal found 6/12![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:03 pm
STL
- SFO
1 stop22h 22m
Frontier
Deal found 6/14![Frontier logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:32 pm
MCI
- SFO
1 stop29h 20m
Frontier
Deal found 6/12![Frontier logo]()
$123
This Frontier deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/134:32 pm
MCI
- SFO
1 stop6h 03m
Frontier
Deal found 6/13![Frontier logo]()
$125
Find flight deals from Missouri to San Francisco
Keep the following information in mind while searching for Missouri to San Francisco flight deals. Data was last updated June 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $307 (Kiwi.com) |
One-way from | $99 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $483 |
Good round-trip deal | $408 or less |
Good one-way deal | $264 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 15, 2026.
Use the filters below to find and compare flights from Missouri to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Tue 9/15
12:23 pm-5:15 pm
1 stop6h 52m
San Francisco
Mon 10/12
5:00 pm-12:21 am
1 stop5h 21m
$337
ColumbiaSan Francisco
COU - SFO
COUSFO
Columbia Regional
Thu 7/9
7:26 pm-12:43 am
1 stop7h 17m
San Francisco
Sat 7/11
5:29 am-4:49 pm
1 stop9h 20m
$338
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Fri 7/31
7:10 pm-10:56 pm
1 stop5h 46m
San Francisco
Fri 8/14
8:48 am-2:33 pm
Nonstop3h 45m
$339
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Mon 11/2
6:00 pm-8:03 pm
Nonstop4h 03m
San Francisco
Sat 11/7
5:20 am-2:31 pm
1 stop7h 11m
$339
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Mon 9/28
11:40 am-5:55 pm
2 stops8h 15m
San Francisco
Tue 9/29
11:15 am-11:10 pm
2 stops9h 55m
$344
SpringfieldSan Francisco
SGF - SFO
SGFSFO
Springfield-Branson
Thu 10/29
3:30 pm-10:51 pm
1 stop9h 21m
San Francisco
Tue 11/3
7:30 am-6:10 pm
1 stop8h 40m
$349
SpringfieldSan Francisco
SGF - SFO
SGFSFO
Springfield-Branson
Thu 7/9
7:40 pm-12:43 am
1 stop7h 03m
San Francisco
Mon 7/13
11:07 pm-10:03 am
1 stop8h 56m
$349
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Sat 9/5
7:42 am-1:26 pm
1 stop7h 44m
San Francisco
Fri 10/23
5:00 pm-12:21 am
1 stop5h 21m
$349
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Thu 8/6
7:59 pm-9:50 pm
Nonstop3h 51m
San Francisco
Mon 8/10
11:30 pm-8:58 am
1 stop7h 28m
$373
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Wed 7/1
7:59 pm-9:50 pm
Nonstop3h 51m
San Francisco
Mon 7/6
10:38 pm-8:42 am
1 stop8h 04m
$374
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Missouri with our price prediction graph.
MCI-SFO
COU-SFO
SGF-SFO
STL-SFO
JLN-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to San Francisco
USMO-SFO
MCI-SFO
COU-SFO
SGF-SFO
STL-SFO
What is the cheapest month to book a flight from Missouri to San Francisco?
Currently, September is the cheapest month in which you can book a flight from Missouri to San Francisco (average of $83). Flying from Missouri to San Francisco in June is currently the most expensive (average of $210). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to SFO?
Find hourly flight availability from Missouri to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 15, 2026.
It’s typically best to fly out from Missouri to San Francisco at noon. Doing so could potentially save you 26% on the flight price compared to flying in the afternoon, which is usually more expensive.
How much does it cost to fly round-trip from Missouri to San Francisco?
How far ahead should I book a flight from Missouri to San Francisco?
Booking 61 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from Missouri to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
Roseville
Cupertino
Emeryville
Newark
San Bruno
Watsonville
San Ramon
Vacaville
San Carlos
Redwood City
Daly City
Sunnyvale
Turlock
Vallejo
San Lorenzo
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to San Francisco
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Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to San Francisco by cabin class
Find flights from Missouri to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and San Francisco flights
Browse other Missouri and San Francisco flight options. Last updated on June 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 15, 2026.
Missouri to San Francisco flights
Consider these flights traveling from Missouri to San Francisco.
Top 6 airlines flying from Missouri to San Francisco
Discover the top 6 airlines that operate flights from Missouri to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$144 | Average$254 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$180 | Average$456 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$216 | Average$357 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$322 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$278 | Average$446 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$284 | Average$476 | FlexibilityNo cancel fee | On-time63% |