$93+ Cheap flights from Missouri to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SFO
Jun 2 — Jun 91
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to San FranciscoExplore the most affordable flight options available from Missouri to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 3, 2026.
Explore the most affordable flight options available from Missouri to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:34 pm
MCI
- SFO
1 stop19h 27m
Frontier
Mon 6/111:59 pm
SFO
- MCI
2 stops35h 50m
Frontier
Deal found 4/30![Frontier logo]()
$289
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:34 pm
MCI
- SFO
1 stop11h 49m
Frontier
Thu 5/286:00 am
SFO
- MCI
1 stop5h 49m
Frontier
Deal found 4/29![Frontier logo]()
$290
This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:34 pm
MCI
- SFO
1 stop11h 49m
Frontier
Tue 5/196:00 am
SFO
- MCI
1 stop5h 49m
Frontier
Deal found 4/28![Frontier logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/22:34 pm
MCI
- SFO
1 stop19h 27m
Frontier
Thu 6/48:41 pm
SFO
- MCI
2 stops18h 48m
Frontier
Deal found 4/30![Frontier logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/302:34 pm
MCI
- SFO
1 stop11h 49m
Frontier
Wed 6/35:25 pm
SFO
- MCI
2 stops18h 24m
Frontier
Deal found 4/29![Frontier logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/301:45 pm
MCI
- SFO
1 stop12h 42m
Frontier
Wed 7/158:23 pm
SFO
- MCI
2 stops42h 58m
Frontier
Deal found 4/29![Frontier logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:34 pm
MCI
- SFO
1 stop11h 49m
Frontier
Sun 5/315:25 pm
SFO
- MCI
2 stops18h 24m
Frontier
Deal found 4/28![Frontier logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/291:45 pm
MCI
- SFO
1 stop9h 13m
Frontier
Tue 7/145:11 pm
SFO
- MCI
2 stops17h 44m
Frontier
Deal found 4/29![Frontier logo]()
$304
This Expedia deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:52 pm
MCI
- SFO
1 stop17h 09m
Multiple Airlines
Thu 6/46:00 am
SFO
- MCI
1 stop5h 49m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:34 pm
MCI
- SFO
1 stop23h 13m
Frontier
Wed 5/2710:01 pm
SFO
- MCI
2 stops37h 48m
Frontier
Deal found 4/28![Frontier logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:34 pm
MCI
- SFO
1 stop11h 49m
Frontier
Sun 6/710:50 pm
SFO
- MCI
2 stops36h 10m
Frontier
Deal found 4/29![Frontier logo]()
$308
This Priceline deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:36 pm
STL
- SFO
1 stop6h 20m
Frontier
Sat 5/238:56 am
SFO
- STL
1 stop8h 27m
Frontier
Deal found 5/1![Frontier logo]()
$310
Best flights from Missouri to San FranciscoDiscover carefully curated flight deals from Missouri to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 3, 2026.
Discover carefully curated flight deals from Missouri to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 3, 2026.
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:00 am
MCI
- SFO
Nonstop3h 50m
United Airlines
Wed 10/214:45 pm
SFO
- MCI
Nonstop3h 33m
United Airlines
Deal found 5/2![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:38 am
SGF
- SFO
1 stop10h 16m
Delta
Tue 7/76:00 am
SFO
- SGF
1 stop10h 08m
Delta
Deal found 4/28![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:35 am
MCI
- SFO
2 stops8h 35m
Southwest
Wed 9/301:25 pm
SFO
- MCI
1 stop5h 45m
Southwest
Deal found 5/1![Southwest logo]()
$388
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:44 am
COU
- SFO
2 stops9h 22m
American Airlines
Wed 6/108:00 am
SFO
- COU
1 stop6h 49m
American Airlines
Deal found 4/29![American Airlines logo]()
$462
This Alaska Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/39:30 am
SGF
- SFO
2 stops12h 42m
Alaska Airlines
Tue 7/76:00 am
SFO
- SGF
2 stops10h 04m
Alaska Airlines
Deal found 4/28![Alaska Airlines logo]()
$552
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:59 pm
MCI
- SFO
Nonstop3h 49m
United Airlines
Tue 7/72:20 pm
SFO
- MCI
1 stop7h 05m
United Airlines
Deal found 4/28![United Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/303:55 pm
MCI
- SFO
1 stop7h 54m
Delta
Mon 8/32:30 pm
SFO
- MCI
1 stop7h 02m
Delta
Deal found 4/28![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:10 pm
MCI
- SFO
1 stop5h 46m
United Airlines
Mon 6/14:29 pm
SFO
- MCI
Nonstop3h 46m
United Airlines
Deal found 5/1![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/119:59 am
MCI
- SFO
1 stop9h 05m
Delta
Wed 7/227:00 am
SFO
- MCI
1 stop5h 50m
Delta
Deal found 5/2![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:45 pm
MCI
- SFO
1 stop8h 05m
Delta
Sun 5/312:43 pm
SFO
- MCI
1 stop7h 16m
Delta
Deal found 5/2![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:23 pm
STL
- SFO
Nonstop4h 20m
United Airlines
Tue 6/25:05 am
SFO
- STL
1 stop8h 41m
United Airlines
Deal found 5/1![United Airlines logo]()
$353
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:25 am
STL
- SFO
Nonstop4h 10m
Southwest
Sun 9/277:55 am
SFO
- STL
2 stops10h 05m
Southwest
Deal found 4/29![Southwest logo]()
$448
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:59 pm
MCI
- SFO
Nonstop3h 50m
United Airlines
Thu 6/46:00 am
SFO
- MCI
1 stop7h 45m
United Airlines
Deal found 4/30![United Airlines logo]()
$360
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:17 pm
COU
- SFO
1 stop7h 53m
American Airlines
Thu 9/36:36 am
SFO
- COU
1 stop8h 10m
American Airlines
Deal found 4/29![American Airlines logo]()
$486
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:57 pm
JLN
- SFO
1 stop7h 43m
United Airlines
Tue 7/76:05 am
SFO
- JLN
1 stop10h 11m
United Airlines
Deal found 4/28![United Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:17 pm
COU
- SFO
1 stop7h 04m
American Airlines
Sun 10/1811:56 pm
SFO
- COU
1 stop9h 11m
American Airlines
Deal found 5/2![American Airlines logo]()
$497
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:25 am
STL
- SFO
Nonstop4h 15m
Southwest
Sun 10/253:05 pm
SFO
- STL
1 stop8h 45m
Southwest
Deal found 4/30![Southwest logo]()
$539
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:59 pm
MCI
- SFO
Nonstop3h 51m
United Airlines
Mon 6/2912:50 am
SFO
- MCI
1 stop7h 39m
United Airlines
Deal found 5/1![United Airlines logo]()
$370
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:23 pm
STL
- SFO
Nonstop4h 20m
United Airlines
Tue 6/96:05 am
SFO
- STL
1 stop7h 41m
United Airlines
Deal found 5/1![United Airlines logo]()
$378
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:52 pm
SGF
- SFO
1 stop7h 54m
Delta
Tue 5/1911:41 am
SFO
- SGF
1 stop8h 38m
Delta
Deal found 4/29![Delta logo]()
$509
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2212:07 pm
SGF
- SFO
1 stop8h 58m
Delta
Mon 5/258:25 am
SFO
- SGF
1 stop7h 39m
Delta
Deal found 5/2![Delta logo]()
$514
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/257:10 pm
MCI
- SFO
1 stop5h 46m
United Airlines
Tue 6/304:29 pm
SFO
- MCI
Nonstop3h 46m
United Airlines
Deal found 5/2![United Airlines logo]()
$398
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:53 pm
SGF
- SFO
1 stop7h 43m
Delta
Sun 8/26:00 am
SFO
- SGF
1 stop10h 08m
Delta
Deal found 4/29![Delta logo]()
$529
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:25 am
SGF
- SFO
1 stop7h 14m
United Airlines
Tue 10/2712:50 am
SFO
- SGF
1 stop7h 44m
United Airlines
Deal found 4/30![United Airlines logo]()
$405
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:59 pm
MCI
- SFO
Nonstop3h 50m
United Airlines
Mon 6/1511:30 pm
SFO
- MCI
1 stop7h 12m
United Airlines
Deal found 5/2![United Airlines logo]()
$406
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:59 pm
MCI
- SFO
Nonstop3h 51m
United Airlines
Mon 6/811:30 pm
SFO
- MCI
1 stop7h 37m
United Airlines
Deal found 4/29![United Airlines logo]()
$406
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/139:00 am
COU
- SFO
1 stop6h 15m
United Airlines
Sun 5/1711:10 pm
SFO
- COU
1 stop9h 45m
United Airlines
Deal found 4/28![United Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:23 pm
STL
- SFO
Nonstop4h 20m
United Airlines
Tue 6/212:12 pm
SFO
- STL
Nonstop4h 05m
United Airlines
Deal found 4/28![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/79:14 am
COU
- SFO
1 stop7h 55m
United Airlines
Fri 7/1012:50 am
SFO
- COU
1 stop7h 58m
United Airlines
Deal found 4/28![United Airlines logo]()
$411
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:23 pm
STL
- SFO
Nonstop4h 20m
United Airlines
Tue 6/912:12 pm
SFO
- STL
Nonstop4h 05m
United Airlines
Deal found 5/1![United Airlines logo]()
$420
Last-minute flights from Missouri to San FranciscoDiscover last-minute flight deals from Missouri to San Francisco. Data last updated May 3, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to San Francisco. Data last updated May 3, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:36 pm
STL
- SFO
1 stop6h 20m
Frontier
Sat 5/238:56 am
SFO
- STL
1 stop8h 27m
Frontier
Deal found 5/1![Frontier logo]()
$310
This Expedia deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:34 pm
MCI
- SFO
1 stop11h 49m
Frontier
Fri 5/1512:52 pm
SFO
- MCI
1 stop22h 57m
Frontier
Deal found 4/29![Frontier logo]()
$310
This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:34 pm
MCI
- SFO
1 stop11h 49m
Frontier
Tue 5/196:00 am
SFO
- MCI
1 stop5h 49m
Frontier
Deal found 4/28![Frontier logo]()
$291
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:34 pm
MCI
- SFO
1 stop11h 49m
Frontier
Thu 5/286:00 am
SFO
- MCI
1 stop5h 49m
Frontier
Deal found 4/29![Frontier logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:34 pm
MCI
- SFO
1 stop23h 13m
Frontier
Wed 5/2710:01 pm
SFO
- MCI
2 stops37h 48m
Frontier
Deal found 4/28![Frontier logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/219:06 pm
STL
- SFO
1 stop13h 43m
Frontier
Thu 6/43:21 pm
SFO
- STL
2 stops39h 34m
Frontier
Deal found 5/2![Frontier logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:34 pm
MCI
- SFO
1 stop11h 49m
Frontier
Sun 5/315:25 pm
SFO
- MCI
2 stops18h 24m
Frontier
Deal found 4/28![Frontier logo]()
$303
This Expedia deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:52 pm
MCI
- SFO
1 stop17h 09m
Multiple Airlines
Thu 6/46:00 am
SFO
- MCI
1 stop5h 49m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:34 pm
MCI
- SFO
1 stop19h 27m
Frontier
Mon 6/111:59 pm
SFO
- MCI
2 stops35h 50m
Frontier
Deal found 4/30![Frontier logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/302:34 pm
MCI
- SFO
1 stop11h 49m
Frontier
Wed 6/35:25 pm
SFO
- MCI
2 stops18h 24m
Frontier
Deal found 4/29![Frontier logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/302:34 pm
MCI
- SFO
1 stop11h 49m
Frontier
Fri 6/512:52 pm
SFO
- MCI
1 stop22h 57m
Frontier
Deal found 4/29![Frontier logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:08 pm
STL
- SFO
1 stop6h 15m
Frontier
Wed 6/1010:58 pm
SFO
- STL
2 stops16h 32m
Frontier
Deal found 5/1![Frontier logo]()
$311
One-way flights from Missouri to San FranciscoSearch for one-way flight options from Missouri to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 3, 2026.
Search for one-way flight options from Missouri to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:51 pm
STL
- SFO
1 stop17h 39m
Frontier
Deal found 4/29![Frontier logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:08 pm
STL
- SFO
1 stop30h 19m
Frontier
Deal found 4/29![Frontier logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/22:34 pm
MCI
- SFO
2 stops31h 02m
Frontier
Deal found 5/1![Frontier logo]()
$102
This Super.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/63:25 pm
STL
- SFO
1 stop9h 39m
Frontier
Deal found 4/29![Frontier logo]()
$104
This Super.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:18 pm
STL
- SFO
1 stop13h 12m
Frontier
Deal found 4/30![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:34 pm
MCI
- SFO
2 stops22h 04m
Frontier
Deal found 4/28![Frontier logo]()
$106
This Super.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:03 pm
STL
- SFO
1 stop17h 22m
Frontier
Deal found 5/2![Frontier logo]()
$110
This Super.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:45 pm
MCI
- SFO
1 stop23h 51m
Frontier
Deal found 4/30![Frontier logo]()
$110
This Orbitz deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:51 pm
STL
- SFO
1 stop23h 50m
Frontier
Deal found 5/1![Frontier logo]()
$111
This Frontier deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/302:34 pm
MCI
- SFO
1 stop11h 49m
Frontier
Deal found 4/30![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/313:30 pm
STL
- SFO
1 stop9h 34m
Frontier
Deal found 5/2![Frontier logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:34 pm
MCI
- SFO
2 stops29h 23m
Frontier
Deal found 5/2![Frontier logo]()
$115
Find flight deals from Missouri to San Francisco
Keep the following information in mind while searching for Missouri to San Francisco flight deals. Data was last updated May 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $289 (Kiwi.com) |
One-way from | $93 (Kiwi.com) |
Popular in | March |
Cheapest in | October |
Average price | $483 |
Good round-trip deal | $409 or less |
Good one-way deal | $274 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
Use the filters below to find and compare flights from Missouri to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Wed 10/14
7:00 am-8:50 am
Nonstop3h 50m
San Francisco
Wed 10/21
4:45 pm-10:18 pm
Nonstop3h 33m
$329
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Fri 7/3
7:59 pm-9:48 pm
Nonstop3h 49m
San Francisco
Tue 7/7
2:20 pm-11:25 pm
1 stop7h 05m
$335
SpringfieldSan Francisco
SGF - SFO
SGFSFO
Springfield-Branson
Fri 7/3
11:38 am-7:54 pm
1 stop10h 16m
San Francisco
Tue 7/7
6:00 am-6:08 pm
1 stop10h 08m
$337
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Fri 5/29
7:10 pm-10:56 pm
1 stop5h 46m
San Francisco
Mon 6/1
4:29 pm-10:15 pm
Nonstop3h 46m
$339
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Thu 7/30
3:55 pm-9:49 pm
1 stop7h 54m
San Francisco
Mon 8/3
2:30 pm-11:32 pm
1 stop7h 02m
$349
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Sat 7/11
9:59 am-5:04 pm
1 stop9h 05m
San Francisco
Wed 7/22
7:00 am-2:50 pm
1 stop5h 50m
$349
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Wed 5/27
5:45 pm-11:50 pm
1 stop8h 05m
San Francisco
Sun 5/31
2:43 pm-11:59 pm
1 stop7h 16m
$349
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Sat 5/30
7:23 pm-9:43 pm
Nonstop4h 20m
San Francisco
Tue 6/2
5:05 am-3:46 pm
1 stop8h 41m
$353
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
Thu 5/28
7:59 pm-9:49 pm
Nonstop3h 50m
San Francisco
Thu 6/4
6:00 am-3:45 pm
1 stop7h 45m
$360
JoplinSan Francisco
JLN - SFO
JLNSFO
Joplin
Fri 7/3
1:57 pm-7:40 pm
1 stop7h 43m
San Francisco
Tue 7/7
6:05 am-6:16 pm
1 stop10h 11m
$364
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Missouri with our price prediction graph.
MCI-SFO
STL-SFO
SGF-SFO
COU-SFO
JLN-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to San Francisco
USMO-SFO
MCI-SFO
STL-SFO
SGF-SFO
COU-SFO
How far ahead should I book a flight from Missouri to San Francisco?
Booking 61 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Missouri to San Francisco?
Currently, September is the cheapest month in which you can book a flight from Missouri to San Francisco (average of $83). Flying from Missouri to San Francisco in March is currently the most expensive (average of $200). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to SFO?
Find hourly flight availability from Missouri to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 3, 2026.
It’s typically best to fly out from Missouri to San Francisco at noon. Doing so could potentially save you 47% on the flight price compared to flying in the afternoon, which is usually more expensive.
Weekly flight availability from Missouri to San Francisco
Explore weekly flight availability from Missouri to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 3, 2026.
The most flights from USMO to SFO are scheduled on a Monday (7 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (3 on average).
How much does it cost to fly round-trip from Missouri to San Francisco?
Related info for your journey
Find useful and relevant information for your journey from Missouri to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
San Bruno
Watsonville
San Ramon
Emeryville
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to San Francisco by cabin class
Find flights from Missouri to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and San Francisco flights
Browse other Missouri and San Francisco flight options. Last updated on May 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 3, 2026.
Missouri to San Francisco flights
Consider these flights traveling from Missouri to San Francisco.
Top 6 airlines flying from Missouri to San Francisco
Discover the top 6 airlines that operate flights from Missouri to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$120 | Average$240 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$176 | Average$427 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$216 | Average$339 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$322 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$278 | Average$437 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$284 | Average$469 | FlexibilityNo cancel fee | On-time63% |