$79+ Cheap flights from St. Louis to San Francisco (STL - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SFO
May 22 — May 291
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Lambert-St Louis to San Francisco are usually found in October or August, booked 17 days in advance, depart on a Friday or Thursday and return on a Thursday
Cheap flight deals from St. Louis to San Francisco
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Last-minute
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Cheapest flights from St. Louis to San FranciscoExplore the most affordable flight options available from St. Louis to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.
Explore the most affordable flight options available from St. Louis to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/144:17 pm
STL
- SFO
1 stop20h 17m
Frontier
Tue 6/235:16 pm
SFO
- STL
2 stops24h 07m
Frontier
Deal found 4/19![Frontier logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:08 pm
STL
- SFO
1 stop6h 19m
Frontier
Thu 6/255:16 pm
SFO
- STL
2 stops24h 07m
Frontier
Deal found 4/21![Frontier logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:36 pm
STL
- SFO
1 stop6h 20m
Frontier
Wed 5/1311:59 pm
SFO
- STL
2 stops17h 24m
Frontier
Deal found 4/18![Frontier logo]()
$332
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:21 am
STL
- SFO
1 stop8h 46m
Delta
Tue 5/264:55 pm
SFO
- STL
1 stop5h 35m
Delta
Deal found 4/20![Delta logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:08 pm
STL
- SFO
1 stop30h 15m
Frontier
Thu 5/149:56 pm
SFO
- STL
2 stops19h 27m
Frontier
Deal found 4/21![Frontier logo]()
$334
This Frontier deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/192:56 pm
STL
- SFO
1 stop7h 00m
Frontier
Tue 6/236:00 am
SFO
- STL
1 stop11h 23m
Frontier
Deal found 4/17![Frontier logo]()
$335
This Super.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:17 pm
STL
- SFO
1 stop14h 56m
Frontier
Mon 4/276:00 am
SFO
- STL
1 stop11h 32m
Frontier
Deal found 4/21![Frontier logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:08 pm
STL
- SFO
2 stops15h 22m
Frontier
Mon 5/186:00 am
SFO
- STL
1 stop11h 23m
Frontier
Deal found 4/19![Frontier logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:08 pm
STL
- SFO
1 stop6h 15m
Frontier
Sun 5/1012:52 pm
SFO
- STL
2 stops18h 03m
Frontier
Deal found 4/18![Frontier logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:18 pm
STL
- SFO
1 stop13h 12m
Frontier
Sun 5/1012:52 pm
SFO
- STL
2 stops18h 03m
Frontier
Deal found 4/18![Frontier logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:51 pm
STL
- SFO
1 stop17h 50m
Multiple Airlines
Wed 5/1312:54 pm
SFO
- STL
1 stop9h 00m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$342
Best flights from St. Louis to San FranciscoDiscover carefully curated flight deals from St. Louis to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2026.
Discover carefully curated flight deals from St. Louis to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2026.
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/244:48 pm
STL
- SFO
1 stop8h 08m
United Airlines
Sat 6/2712:12 pm
SFO
- STL
Nonstop4h 05m
United Airlines
Deal found 4/17![United Airlines logo]()
$443
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:19 am
STL
- SFO
1 stop9h 30m
Delta
Tue 5/1211:59 pm
SFO
- STL
1 stop7h 45m
Delta
Deal found 4/17![Delta logo]()
$523
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:15 am
STL
- SFO
Nonstop4h 05m
Southwest
Sat 8/89:25 am
SFO
- STL
Nonstop3h 50m
Southwest
Deal found 4/21![Southwest logo]()
$529
This Alaska Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:00 am
STL
- SFO
2 stops12h 21m
Alaska Airlines
Wed 5/138:23 am
SFO
- STL
1 stop8h 22m
Alaska Airlines
Deal found 4/19![Alaska Airlines logo]()
$541
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:30 am
STL
- SFO
Nonstop4h 41m
United Airlines
Sun 5/176:45 am
SFO
- STL
1 stop8h 12m
United Airlines
Deal found 4/20![United Airlines logo]()
$522
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:23 pm
STL
- SFO
Nonstop4h 20m
United Airlines
Sat 7/2512:12 pm
SFO
- STL
Nonstop4h 05m
United Airlines
Deal found 4/18![United Airlines logo]()
$529
This Alaska Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:33 pm
STL
- SFO
1 stop17h 28m
Alaska Airlines
Sun 5/319:57 am
SFO
- STL
2 stops11h 57m
Alaska Airlines
Deal found 4/20![Alaska Airlines logo]()
$614
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:23 pm
STL
- SFO
Nonstop4h 20m
United Airlines
Sun 7/512:12 pm
SFO
- STL
Nonstop4h 05m
United Airlines
Deal found 4/21![United Airlines logo]()
$529
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:10 am
STL
- SFO
1 stop6h 08m
United Airlines
Sat 6/2712:12 pm
SFO
- STL
Nonstop4h 05m
United Airlines
Deal found 4/19![United Airlines logo]()
$539
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:45 am
STL
- SFO
1 stop7h 27m
United Airlines
Mon 5/2512:12 pm
SFO
- STL
Nonstop4h 05m
United Airlines
Deal found 4/17![United Airlines logo]()
$626
Last-minute flights from St. Louis to San FranciscoDiscover last-minute flight deals from St. Louis to San Francisco. Data last updated April 22, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to San Francisco. Data last updated April 22, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:17 pm
STL
- SFO
1 stop14h 56m
Frontier
Mon 4/276:00 am
SFO
- STL
1 stop11h 32m
Frontier
Deal found 4/21![Frontier logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:55 pm
STL
- SFO
1 stop16h 27m
Frontier
Sat 5/27:40 pm
SFO
- STL
2 stops25h 39m
Frontier
Deal found 4/17![Frontier logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:51 pm
STL
- SFO
1 stop17h 50m
Multiple Airlines
Wed 5/1312:54 pm
SFO
- STL
1 stop9h 00m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:36 pm
STL
- SFO
1 stop6h 20m
Frontier
Wed 5/1311:59 pm
SFO
- STL
2 stops17h 24m
Frontier
Deal found 4/18![Frontier logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:18 pm
STL
- SFO
1 stop13h 12m
Frontier
Sun 5/1012:52 pm
SFO
- STL
2 stops18h 03m
Frontier
Deal found 4/18![Frontier logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:08 pm
STL
- SFO
1 stop6h 15m
Frontier
Sun 5/1012:52 pm
SFO
- STL
2 stops18h 03m
Frontier
Deal found 4/18![Frontier logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:08 pm
STL
- SFO
1 stop30h 15m
Frontier
Thu 5/149:56 pm
SFO
- STL
2 stops19h 27m
Frontier
Deal found 4/21![Frontier logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:08 pm
STL
- SFO
2 stops15h 22m
Frontier
Mon 5/186:00 am
SFO
- STL
1 stop11h 23m
Frontier
Deal found 4/19![Frontier logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:51 pm
STL
- SFO
2 stops18h 56m
Frontier
Tue 5/268:44 pm
SFO
- STL
1 stop19h 22m
Frontier
Deal found 4/19![Frontier logo]()
$335
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:21 am
STL
- SFO
1 stop8h 46m
Delta
Tue 5/264:55 pm
SFO
- STL
1 stop5h 35m
Delta
Deal found 4/20![Delta logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:08 pm
STL
- SFO
1 stop13h 53m
Frontier
Sun 5/246:00 am
SFO
- STL
1 stop11h 23m
Frontier
Deal found 4/20![Frontier logo]()
$344
One-way flights from St. Louis to San FranciscoSearch for one-way flight options from St. Louis to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 22, 2026.
Search for one-way flight options from St. Louis to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 22, 2026.
This Super.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:36 pm
STL
- SFO
1 stop6h 20m
Frontier
Deal found 4/21![Frontier logo]()
$79
This Frontier deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:18 pm
STL
- SFO
1 stop13h 12m
Frontier
Deal found 4/17![Frontier logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/119:18 pm
STL
- SFO
1 stop15h 23m
Frontier
Deal found 4/17![Frontier logo]()
$93
This Super.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:08 pm
STL
- SFO
1 stop6h 15m
Frontier
Deal found 4/17![Frontier logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:51 pm
STL
- SFO
1 stop17h 50m
Frontier
Deal found 4/21![Frontier logo]()
$105
This Super.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/304:17 pm
STL
- SFO
1 stop20h 17m
Frontier
Deal found 4/17![Frontier logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:08 pm
STL
- SFO
1 stop6h 14m
Frontier
Deal found 4/17![Frontier logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:51 pm
STL
- SFO
1 stop21h 50m
Frontier
Deal found 4/17![Frontier logo]()
$118
This Frontier deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:08 pm
STL
- SFO
1 stop6h 19m
Frontier
Deal found 4/17![Frontier logo]()
$125
This Super.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:51 pm
STL
- SFO
1 stop26h 58m
Frontier
Deal found 4/21![Frontier logo]()
$129
This Trip.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/128:21 pm
STL
- SFO
1 stop14h 25m
Frontier
Deal found 4/22![Frontier logo]()
$134
Find flight deals from St. Louis to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $328 (Kiwi.com) |
One-way from | $79 (Super.com) |
Popular in | March |
Cheapest in | October |
Average price | $481 |
Good round-trip deal | $532 or less |
Good one-way deal | $274 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
Use the filters below to find and compare flights from St. Louis to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Wed 6/24
4:48 pm-10:56 pm
1 stop8h 08m
San Francisco
Sat 6/27
12:12 pm-6:17 pm
Nonstop4h 05m
$443
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Tue 5/12
8:30 am-11:11 am
Nonstop4h 41m
San Francisco
Sun 5/17
6:45 am-4:57 pm
1 stop8h 12m
$522
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Tue 5/12
10:19 am-5:49 pm
1 stop9h 30m
San Francisco
Tue 5/12
11:59 pm-9:44 am
1 stop7h 45m
$523
Quickest round-trip
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Mon 8/3
8:15 am-10:20 am
Nonstop4h 05m
San Francisco
Sat 8/8
9:25 am-3:15 pm
Nonstop3h 50m
$529
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Thu 7/16
7:23 pm-9:43 pm
Nonstop4h 20m
San Francisco
Sat 7/25
12:12 pm-6:17 pm
Nonstop4h 05m
$529
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Fri 6/26
7:23 pm-9:43 pm
Nonstop4h 20m
San Francisco
Sun 7/5
12:12 pm-6:17 pm
Nonstop4h 05m
$529
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Sun 6/21
5:10 am-9:18 am
1 stop6h 08m
San Francisco
Sat 6/27
12:12 pm-6:17 pm
Nonstop4h 05m
$539
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Sat 5/9
7:00 am-5:21 pm
2 stops12h 21m
San Francisco
Wed 5/13
8:23 am-6:45 pm
1 stop8h 22m
$541
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Thu 5/28
5:33 pm-9:01 am
1 stop17h 28m
San Francisco
Sun 5/31
9:57 am-11:54 pm
2 stops11h 57m
$614
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
Wed 5/20
7:45 am-1:12 pm
1 stop7h 27m
San Francisco
Mon 5/25
12:12 pm-6:17 pm
Nonstop4h 05m
$626
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from St. Louis to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to San Francisco in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on St. Louis-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from St. Louis with our price prediction graph.
STL-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to San Francisco
Prices
Airlines
How far ahead should I book a flight from St. Louis to San Francisco?
Use this chart to determine the optimal time to book a round-trip flight from St. Louis to San Francisco. Price data was last updated on April 17, 2026.
The best time to book flights from St. Louis to San Francisco is 17 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from St. Louis to San Francisco?
Currently, October is the cheapest month in which you can book a flight from St. Louis to San Francisco (average of $365). Flying from St. Louis to San Francisco in March is currently the most expensive (average of $543). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from STL to SFO?
Find hourly flight availability from St. Louis to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2026.
It’s typically best to fly out from St. Louis to San Francisco at noon. Doing so could potentially save you 61% on the flight price compared to flying in the evening, which is usually more expensive.
The best insider tips for St. Louis to San Francisco flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your St. Louis to San Francisco trip
Our travel experts
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated April 22, 2026.
Read through reviews of airlines operating flights from St. Louis to San Francisco, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from St. Louis to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Rancho Cordova
San Bruno
Watsonville
San Ramon
Union City
Emeryville
Newark
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
San Lorenzo
Davis
Manteca
Elk Grove
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St. Louis and San Francisco flights
Browse other St. Louis and San Francisco flight options. Last updated on April 22, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on April 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 22, 2026.
Top 5 airlines flying from St. Louis to San Francisco
Discover the top 5 airlines that operate flights from St. Louis to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$122 | Average$250 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$180 | Average$392 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$376 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$291 | Average$486 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$332 | Average$500 | FlexibilityNo cancel fee | On-time63% |