$94+ Cheap flights from St. Louis to San Diego (STL - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SAN
Aug 24 — Aug 311
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Lambert-St Louis to San Diego are usually found in September or October, booked 36 days in advance, depart on a Wednesday or Thursday and return on a Thursday
Cheap flight deals from St. Louis to San Diego
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to San DiegoExplore the most affordable flight options available from St. Louis to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 25, 2026.
Explore the most affordable flight options available from St. Louis to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:46 pm
STL
- SAN
1 stop25h 39m
Frontier
Mon 9/216:25 am
SAN
- STL
1 stop10h 50m
Frontier
Deal found 7/20![Frontier logo]()
$256
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:45 pm
STL
- SAN
1 stop27h 19m
Frontier
Mon 8/318:59 pm
SAN
- STL
1 stop18h 51m
Frontier
Deal found 7/22![Frontier logo]()
$258
This Travelocity deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:08 pm
STL
- SAN
1 stop15h 02m
Frontier
Mon 8/108:51 pm
SAN
- STL
1 stop19h 14m
Frontier
Deal found 7/23![Frontier logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:08 pm
STL
- SAN
1 stop15h 02m
Frontier
Tue 8/113:03 pm
SAN
- STL
2 stops26h 20m
Frontier
Deal found 7/21![Frontier logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:46 pm
STL
- SAN
1 stop10h 02m
Frontier
Mon 9/288:32 pm
SAN
- STL
2 stops35h 08m
Frontier
Deal found 7/22![Frontier logo]()
$261
This Super.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Mon 8/178:51 pm
SAN
- STL
1 stop18h 59m
Frontier
Deal found 7/24![Frontier logo]()
$262
This CheapOair deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:45 pm
STL
- SAN
1 stop27h 29m
Frontier
Sun 8/308:59 pm
SAN
- STL
1 stop18h 51m
Frontier
Deal found 7/20![Frontier logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:35 am
STL
- SAN
2 stops31h 06m
Frontier
Wed 11/188:32 pm
SAN
- STL
1 stop20h 43m
Frontier
Deal found 7/22![Frontier logo]()
$266
This Booking.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:45 pm
STL
- SAN
1 stop27h 29m
Multiple Airlines
Tue 8/256:55 am
SAN
- STL
1 stop8h 15m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$267
This Expedia deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:08 pm
STL
- SAN
1 stop15h 02m
Frontier
Sat 8/156:35 am
SAN
- STL
1 stop6h 21m
Frontier
Deal found 7/22![Frontier logo]()
$268
Best flights from St. Louis to San DiegoDiscover carefully curated flight deals from St. Louis to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 25, 2026.
Discover carefully curated flight deals from St. Louis to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 25, 2026.
This Alaska Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:29 am
STL
- SAN
1 stop8h 52m
Alaska Airlines
Wed 9/306:55 am
SAN
- STL
1 stop8h 15m
Alaska Airlines
Deal found 7/24![Alaska Airlines logo]()
$283
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:30 pm
STL
- SAN
1 stop6h 40m
United Airlines
Mon 8/316:20 am
SAN
- STL
2 stops8h 14m
United Airlines
Deal found 7/19![United Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/73:39 pm
STL
- SAN
1 stop9h 21m
Delta
Sun 8/99:30 pm
SAN
- STL
1 stop8h 38m
Delta
Deal found 7/22![Delta logo]()
$307
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:50 pm
STL
- SAN
2 stops7h 40m
Southwest
Tue 9/89:05 am
SAN
- STL
2 stops7h 40m
Southwest
Deal found 7/24![Southwest logo]()
$382
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:28 pm
STL
- SAN
1 stop7h 47m
Delta
Sun 10/259:45 pm
SAN
- STL
1 stop9h 04m
Delta
Deal found 7/23![Delta logo]()
$307
This Alaska Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:08 pm
STL
- SAN
1 stop18h 22m
Alaska Airlines
Tue 9/88:06 pm
SAN
- STL
2 stops16h 15m
Alaska Airlines
Deal found 7/21![Alaska Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:15 am
STL
- SAN
1 stop6h 29m
Delta
Sat 9/193:20 pm
SAN
- STL
1 stop5h 56m
Delta
Deal found 7/21![Delta logo]()
$307
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:36 pm
STL
- SAN
2 stops8h 19m
United Airlines
Fri 8/1410:40 pm
SAN
- STL
1 stop9h 32m
United Airlines
Deal found 7/21![United Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1712:59 pm
STL
- SAN
2 stops8h 56m
United Airlines
Fri 8/2111:00 am
SAN
- STL
1 stop7h 46m
United Airlines
Deal found 7/20![United Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:23 pm
STL
- SAN
1 stop7h 08m
United Airlines
Wed 8/126:20 am
SAN
- STL
2 stops8h 14m
United Airlines
Deal found 7/24![United Airlines logo]()
$412
Last-minute flights from St. Louis to San DiegoDiscover last-minute flight deals from St. Louis to San Diego. Data last updated July 25, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to San Diego. Data last updated July 25, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:03 pm
STL
- SAN
1 stop21h 05m
Frontier
Tue 8/116:35 am
SAN
- STL
2 stops24h 22m
Frontier
Deal found 7/21![Frontier logo]()
$274
This Travelocity deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:08 pm
STL
- SAN
1 stop15h 02m
Frontier
Mon 8/108:51 pm
SAN
- STL
1 stop19h 14m
Frontier
Deal found 7/23![Frontier logo]()
$259
This Expedia deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:08 pm
STL
- SAN
1 stop15h 02m
Frontier
Sat 8/156:35 am
SAN
- STL
1 stop6h 21m
Frontier
Deal found 7/22![Frontier logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:08 pm
STL
- SAN
1 stop15h 02m
Frontier
Tue 8/113:03 pm
SAN
- STL
2 stops26h 20m
Frontier
Deal found 7/21![Frontier logo]()
$260
This Super.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Mon 8/178:51 pm
SAN
- STL
1 stop18h 59m
Frontier
Deal found 7/24![Frontier logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:08 pm
STL
- SAN
2 stops20h 00m
Frontier
Thu 8/1310:10 am
SAN
- STL
1 stop7h 13m
Frontier
Deal found 7/21![Frontier logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Wed 8/126:35 am
SAN
- STL
2 stops33h 02m
Frontier
Deal found 7/20![Frontier logo]()
$273
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:45 pm
STL
- SAN
1 stop27h 19m
Frontier
Mon 8/318:59 pm
SAN
- STL
1 stop18h 51m
Frontier
Deal found 7/22![Frontier logo]()
$258
This Booking.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:45 pm
STL
- SAN
1 stop27h 29m
Multiple Airlines
Tue 8/256:55 am
SAN
- STL
1 stop8h 15m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$267
This CheapOair deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:45 pm
STL
- SAN
1 stop27h 29m
Frontier
Sun 8/308:59 pm
SAN
- STL
1 stop18h 51m
Frontier
Deal found 7/20![Frontier logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:17 pm
STL
- SAN
2 stops23h 24m
Frontier
Thu 9/36:25 am
SAN
- STL
1 stop10h 48m
Frontier
Deal found 7/23![Frontier logo]()
$276
One-way flights from St. Louis to San DiegoSearch for one-way flight options from St. Louis to San Diego. Find affordable one-way fares based on user searches. Data last updated July 25, 2026.
Search for one-way flight options from St. Louis to San Diego. Find affordable one-way fares based on user searches. Data last updated July 25, 2026.
This Alaska Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:02 am
STL
- SAN
1 stop9h 38m
Alaska Airlines
Deal found 7/22![Alaska Airlines logo]()
$94
This Alaska Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:08 pm
STL
- SAN
1 stop18h 22m
Alaska Airlines
Deal found 7/21![Alaska Airlines logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:10 pm
STL
- SAN
1 stop21h 31m
Frontier
Deal found 7/22![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:58 pm
STL
- SAN
1 stop15h 07m
Frontier
Deal found 7/22![Frontier logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:17 pm
STL
- SAN
2 stops40h 48m
Frontier
Deal found 7/20![Frontier logo]()
$108
This CheapOair deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:08 pm
STL
- SAN
1 stop18h 22m
Alaska Airlines
Deal found 7/20![Alaska Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:17 pm
STL
- SAN
2 stops31h 34m
Frontier
Deal found 7/20![Frontier logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:17 pm
STL
- SAN
2 stops40h 48m
Frontier
Deal found 7/20![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2210:35 am
STL
- SAN
2 stops39h 24m
Frontier
Deal found 7/22![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:10 pm
STL
- SAN
2 stops26h 38m
Frontier
Deal found 7/23![Frontier logo]()
$117
Find flight deals from St. Louis to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $256 (Kiwi.com) |
One-way from | $94 (Alaska Airlines) |
Popular in | December |
Cheapest in | September |
Average price | $370 |
Good round-trip deal | $473 or less |
Good one-way deal | $230 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2026.
Use the filters below to find and compare flights from St. Louis to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Sun 9/27
6:29 am-1:21 pm
1 stop8h 52m
San Diego
Wed 9/30
6:55 am-5:10 pm
1 stop8h 15m
$283
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Wed 8/26
5:30 pm-10:10 pm
1 stop6h 40m
San Diego
Mon 8/31
6:20 am-4:34 pm
2 stops8h 14m
$302
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Fri 8/7
3:39 pm-11:00 pm
1 stop9h 21m
San Diego
Sun 8/9
9:30 pm-8:08 am
1 stop8h 38m
$307
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Fri 10/16
5:28 pm-11:15 pm
1 stop7h 47m
San Diego
Sun 10/25
9:45 pm-8:49 am
1 stop9h 04m
$307
Quickest round-trip
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Sat 9/19
6:15 am-10:44 am
1 stop6h 29m
San Diego
Sat 9/19
3:20 pm-11:16 pm
1 stop5h 56m
$307
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Sat 9/5
6:08 pm-10:30 am
1 stop18h 22m
San Diego
Tue 9/8
8:06 pm-2:21 pm
2 stops16h 15m
$310
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Wed 9/2
2:50 pm-8:30 pm
2 stops7h 40m
San Diego
Tue 9/8
9:05 am-6:45 pm
2 stops7h 40m
$382
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Tue 8/11
1:36 pm-7:55 pm
2 stops8h 19m
San Diego
Fri 8/14
10:40 pm-10:12 am
1 stop9h 32m
$402
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Mon 8/17
12:59 pm-7:55 pm
2 stops8h 56m
San Diego
Fri 8/21
11:00 am-8:46 pm
1 stop7h 46m
$402
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Sat 8/8
7:23 pm-12:31 am
1 stop7h 08m
San Diego
Wed 8/12
6:20 am-4:34 pm
2 stops8h 14m
$412
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from St. Louis to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to San Diego in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from St. Louis with our price prediction graph.
STL-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to San Diego
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How far ahead should I book a flight from St. Louis to San Diego?
To ensure you get the cheapest price possible for a flight from St. Louis to San Diego, you should look to book at least 35 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from St. Louis to San Diego?
Currently, September is the cheapest month in which you can book a flight from St. Louis to San Diego (average of $309). Flying from St. Louis to San Diego in January is currently the most expensive (average of $442). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from STL to SAN?
Find hourly flight availability from St. Louis to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 25, 2026.
Unlike at noon, when flights are generally more expensive, you can save up to 27% on flights from St. Louis to San Diego by exploring options for tickets in the afternoon.
What’s the top layover airport for flights from St. Louis to San Diego?
Share of 1-stop round-trip flights from St. Louis to San Diego chosen by Cheapflights users in the past 12 months, using the same layover each way.
Salt Lake City (SLC) – chosen by Cheapflights users on 50% of 1-stop itineraries from St. Louis to San Diego on Cheapflights.
What’s the cheapest layover airport for flights from St. Louis to San Diego?
Average round-trip fare for 1-stop flights from St. Louis to San Diego, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Las Vegas (LAS) is the most affordable 1-stop option, with an average round-trip price of $176.
What’s the fastest layover option from St. Louis to San Diego?
Shortest average travel time for 1-stop one-way flights from St. Louis to San Diego, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Salt Lake City (SLC) have the shortest average one-way travel time for 1-stop routes: 6h 19m.
Which airport typically offers the quickest layover for flights from St. Louis to San Diego?
Average layover duration for 1-stop one-way flights from St. Louis to San Diego, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Salt Lake City (SLC) offer the fastest connection on this route, with an average layover time of 0h 53m.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated July 25, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from St. Louis to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Related info for your journey
Find useful and relevant information for your journey from St. Louis to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
Poway
La Mesa
Coronado
Santee
San Ysidro
Julian
Lemon Grove
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St. Louis and San Diego flights
Browse other St. Louis and San Diego flight options. Last updated on July 25, 2026.
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Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on July 25, 2026.
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Top 5 airlines flying from St. Louis to San Diego
Discover the top 5 airlines that operate flights from St. Louis to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$144 | Average$253 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$182 | Average$334 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$226 | Average$378 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$324 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$280 | Average$450 | FlexibilityNo cancel fee | On-time63% |