$93+ Cheap flights from St. Louis to San Diego (STL - SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SAN
Oct 11 — Oct 181
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Lambert-St Louis to San Diego are usually found in July or September, booked 70 days in advance, depart on a Thursday or Wednesday and return on a Thursday
Cheap flight deals from St. Louis to San Diego
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to San DiegoExplore the most affordable flight options available from St. Louis to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
Explore the most affordable flight options available from St. Louis to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:59 pm -
1 stop5h 58m
Tue 11/34:53 pm -
2 stops22h 47m
Deal found 9/7![Frontier logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:59 pm -
1 stop5h 58m
Thu 11/58:32 pm -
1 stop14h 01m
Deal found 9/6![Frontier logo]()
$264
This Expedia deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:10 pm -
1 stop5h 41m
Tue 10/1311:10 am -
1 stop10h 49m
Deal found 9/7![Multiple Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:59 pm -
1 stop5h 58m
Tue 11/34:53 pm -
1 stop20h 30m
Deal found 9/7![Frontier logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:59 pm -
1 stop5h 58m
Sun 11/158:32 pm -
1 stop14h 01m
Deal found 9/10![Frontier logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:10 pm -
1 stop5h 41m
Tue 10/66:25 am -
2 stops28h 45m
Deal found 9/7![Frontier logo]()
$282
This Travelocity deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:02 am -
1 stop8h 21m
Sat 10/246:25 am -
1 stop10h 32m
Deal found 9/7![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:10 pm -
1 stop5h 41m
Tue 10/65:54 pm -
1 stop15h 38m
Deal found 9/11![Frontier logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:00 pm -
1 stop5h 56m
Mon 10/198:34 pm -
2 stops40h 50m
Deal found 9/8![Frontier logo]()
$285
This Frontier deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:10 pm -
1 stop5h 41m
Wed 10/146:25 am -
1 stop6h 59m
Deal found 9/8![Frontier logo]()
$287
Best flights from St. Louis to San DiegoDiscover carefully curated flight deals from St. Louis to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
Discover carefully curated flight deals from St. Louis to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:28 pm -
2 stops10h 24m
Tue 12/157:20 am -
2 stops12h 08m
Deal found 9/10![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/208:25 am -
Nonstop4h 00m
Fri 1/2211:10 am -
Nonstop3h 25m
Deal found 9/10![Southwest logo]()
$376
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:00 pm -
1 stop7h 40m
Mon 11/233:40 pm -
1 stop5h 38m
Deal found 9/10![Delta logo]()
$327
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:00 pm -
1 stop6h 53m
Wed 11/259:43 am -
1 stop5h 58m
Deal found 9/8![Delta logo]()
$327
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/157:08 am -
2 stops12h 42m
Tue 1/56:20 am -
1 stop6h 11m
Deal found 9/6![Delta logo]()
$340
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:20 pm -
2 stops10h 34m
Sun 11/156:15 am -
1 stop8h 16m
Deal found 9/6![Delta logo]()
$340
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/146:30 am -
1 stop8h 30m
Sat 2/206:50 am -
2 stops12h 51m
Deal found 9/7![Delta logo]()
$340
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:03 am -
2 stops10h 48m
Mon 12/146:15 am -
1 stop8h 09m
Deal found 9/9![Delta logo]()
$340
Last-minute flights from St. Louis to San DiegoDiscover last-minute flight deals from St. Louis to San Diego. Data last updated September 11, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to San Diego. Data last updated September 11, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:10 pm -
1 stop5h 41m
Tue 10/65:54 pm -
1 stop15h 38m
Deal found 9/11![Frontier logo]()
$284
This Trip.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:20 am -
1 stop9h 40m
Mon 10/59:03 pm -
1 stop12h 29m
Deal found 9/11![Frontier logo]()
$281
This Expedia deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:10 pm -
1 stop5h 41m
Tue 10/1311:10 am -
1 stop10h 49m
Deal found 9/7![Multiple Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:10 pm -
1 stop5h 41m
Tue 10/66:25 am -
2 stops28h 45m
Deal found 9/7![Frontier logo]()
$282
This Expedia deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/410:20 am -
1 stop9h 40m
Sun 10/118:34 pm -
1 stop14h 01m
Deal found 9/6![Frontier logo]()
$288
This Frontier deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:10 pm -
1 stop5h 41m
Wed 10/146:25 am -
1 stop6h 59m
Deal found 9/8![Frontier logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:35 pm -
2 stops31h 21m
Thu 10/158:34 pm -
1 stop14h 01m
Deal found 9/9![Frontier logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:00 pm -
1 stop5h 56m
Mon 10/198:34 pm -
2 stops40h 50m
Deal found 9/8![Frontier logo]()
$285
This Travelocity deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:02 am -
1 stop8h 21m
Sat 10/246:25 am -
1 stop10h 32m
Deal found 9/7![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:59 pm -
1 stop5h 58m
Tue 11/34:53 pm -
2 stops22h 47m
Deal found 9/7![Frontier logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:59 pm -
1 stop5h 58m
Tue 11/34:53 pm -
1 stop20h 30m
Deal found 9/7![Frontier logo]()
$280
One-way flights from St. Louis to San DiegoSearch for one-way flight options from St. Louis to San Diego. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
Search for one-way flight options from St. Louis to San Diego. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
This Priceline deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:42 pm -
1 stop6h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Frontier logo]()
$93
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:59 pm -
1 stop21h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:59 pm -
1 stop5h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:10 pm -
2 stops20h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Frontier logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Mon 10/58:10 pm -
2 stops15h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Frontier logo]()
$119
This Trip.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:42 pm -
1 stop6h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$122
This Frontier deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:28 pm -
1 stop8h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$124
This Booking.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:00 pm -
1 stop21h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$125
Find flight deals from St. Louis to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $262 (Kiwi.com) |
One-way from | $93 (Priceline) |
Popular in | January |
Cheapest in | July |
Average price | $385 |
Good round-trip deal | $510 or less |
Good one-way deal | $359 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
Use the filters below to find and compare flights from St. Louis to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSan Diego
STL Lambert-St Louis - SAN San Diego
STLSAN
Lambert-St Louis
Sun 11/8
8:00 am-1:47 pm
1 stop7h 47m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$159
St. LouisSan Diego
STL Lambert-St Louis - SAN San Diego
STLSAN
Lambert-St Louis
Sun 9/20
6:08 pm-10:30 am
1 stop18h 22m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$159
St. LouisSan Diego
STL Lambert-St Louis - SAN San Diego
STLSAN
Lambert-St Louis
Tue 3/9
10:45 am-6:27 pm
1 stop9h 42m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$164
St. LouisSan Diego
STL Lambert-St Louis - SAN San Diego
STLSAN
Lambert-St Louis
Sun 10/25
5:35 pm-11:48 pm
1 stop8h 13m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$164
St. LouisSan Diego
STL Lambert-St Louis - SAN San Diego
STLSAN
Lambert-St Louis
Tue 10/13
7:02 am-1:23 pm
1 stop8h 21m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$164
St. LouisSan Diego
STL Lambert-St Louis - SAN San Diego
STLSAN
Lambert-St Louis
Thu 12/10
5:25 am-11:27 am
1 stop8h 02m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$164
Quickest round-trip
St. LouisSan Diego
STL Lambert-St Louis - SAN San Diego
STLSAN
Lambert-St Louis
Sun 10/18
6:15 am-10:58 am
1 stop6h 43m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$164
St. LouisSan Diego
STL Lambert-St Louis - SAN San Diego
STLSAN
Lambert-St Louis
Wed 3/10
2:15 pm-10:49 pm
2 stops10h 34m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$177
St. LouisSan Diego
STL Lambert-St Louis - SAN San Diego
STLSAN
Lambert-St Louis
Sat 11/7
11:20 am-10:51 pm
2 stops13h 31m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$177
St. LouisSan Diego
STL Lambert-St Louis - SAN San Diego
STLSAN
Lambert-St Louis
Tue 12/29
3:58 pm-9:16 pm
1 stop7h 18m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$200
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from St. Louis to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to San Diego in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from St. Louis with our price prediction graph.
STL-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to San Diego
Prices
More
How far ahead should I book a flight from St. Louis to San Diego?
To ensure you get the cheapest price possible for a flight from St. Louis to San Diego, you should look to book at least 69 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from St. Louis to San Diego?
Currently, July is the cheapest month in which you can book a flight from St. Louis to San Diego (average of $373). Flying from St. Louis to San Diego in January is currently the most expensive (average of $442). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from STL to SAN?
Find hourly flight availability from St. Louis to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2026.
Unlike at noon, when flights are generally more expensive, you can save up to 29% on flights from St. Louis to San Diego by exploring options for tickets in the afternoon.
What’s the top layover airport for flights from St. Louis to San Diego?
Share of 1-stop round-trip flights from St. Louis to San Diego chosen by Cheapflights users in the past 12 months, using the same layover each way.
Salt Lake City (SLC) – chosen by Cheapflights users on 33% of 1-stop itineraries from St. Louis to San Diego on Cheapflights.
What’s the cheapest layover airport for flights from St. Louis to San Diego?
Average round-trip fare for 1-stop flights from St. Louis to San Diego, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Las Vegas (LAS) is the most affordable 1-stop option, with an average round-trip price of $176.
What’s the fastest layover option from St. Louis to San Diego?
Shortest average travel time for 1-stop one-way flights from St. Louis to San Diego, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Denver (DEN) have the shortest average one-way travel time for 1-stop routes: 5h 41m.
Which airport typically offers the quickest layover for flights from St. Louis to San Diego?
Average layover duration for 1-stop one-way flights from St. Louis to San Diego, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Salt Lake City (SLC) offer the fastest connection on this route, with an average layover time of 0h 53m.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 11, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from St. Louis to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Related info for your journey
Find useful and relevant information for your journey from St. Louis to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top 6 airlines flying from St. Louis to San Diego
Discover the top 6 airlines that operate flights from St. Louis to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$144 | Average$278 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$209 | Average$331 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$222 | Average$312 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$231 | Average$384 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$266 | Average$418 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$289 | Average$454 | FlexibilityNo cancel fee | On-time63% |