$94+ Cheap flights from St. Louis to San Diego (STL - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/4. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SAN
Jul 11 — Jul 181
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Lambert-St Louis to San Diego are usually found in September or October, booked 36 days in advance, depart on a Wednesday or Thursday and return on a Thursday
Cheap flight deals from St. Louis to San Diego
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Last-minute
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Cheapest flights from St. Louis to San DiegoExplore the most affordable flight options available from St. Louis to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.
Explore the most affordable flight options available from St. Louis to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.
This Frontier deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:08 pm
STL
- SAN
1 stop5h 45m
Frontier
Thu 7/96:25 am
SAN
- STL
1 stop10h 58m
Frontier
Deal found 6/6![Frontier logo]()
$274
This Expedia deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Sun 7/198:51 pm
SAN
- STL
1 stop19h 24m
Frontier
Deal found 6/10![Frontier logo]()
$283
This CheapOair deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Sat 7/186:25 am
SAN
- STL
1 stop10h 58m
Frontier
Deal found 6/9![Frontier logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:46 pm
STL
- SAN
1 stop15h 05m
Frontier
Wed 7/83:03 pm
SAN
- STL
1 stop25h 12m
Frontier
Deal found 6/6![Frontier logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:03 pm
STL
- SAN
1 stop21h 05m
Frontier
Tue 7/217:46 pm
SAN
- STL
2 stops44h 29m
Frontier
Deal found 6/8![Frontier logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:10 pm
STL
- SAN
1 stop20h 58m
Frontier
Fri 7/316:25 am
SAN
- STL
1 stop10h 58m
Frontier
Deal found 6/7![Frontier logo]()
$287
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:55 pm
STL
- SAN
1 stop9h 58m
Delta
Sun 9/2010:30 pm
SAN
- STL
1 stop8h 25m
Delta
Deal found 6/10![Delta logo]()
$288
This CheapOair deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Wed 7/293:03 pm
SAN
- STL
1 stop25h 12m
Frontier
Deal found 6/11![Frontier logo]()
$289
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:25 am
STL
- SAN
Nonstop3h 45m
Southwest
Sun 8/2311:40 am
SAN
- STL
1 stop6h 20m
Southwest
Deal found 6/8![Southwest logo]()
$292
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:25 am
STL
- SAN
Nonstop3h 45m
Southwest
Tue 8/183:25 pm
SAN
- STL
1 stop5h 20m
Southwest
Deal found 6/10![Southwest logo]()
$294
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:33 am
STL
- SAN
1 stop9h 41m
Delta
Mon 9/711:48 am
SAN
- STL
1 stop8h 15m
Delta
Deal found 6/8![Delta logo]()
$297
This deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/308:08 pm
STL
- SAN
1 stop5h 45m
Frontier
Tue 9/86:25 am
SAN
- STL
1 stop6h 23m
Frontier
Deal found 6/10![Frontier logo]()
$299
Best flights from St. Louis to San DiegoDiscover carefully curated flight deals from St. Louis to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 11, 2026.
Discover carefully curated flight deals from St. Louis to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 11, 2026.
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:10 pm
STL
- SAN
1 stop10h 06m
Delta
Mon 9/711:48 am
SAN
- STL
1 stop8h 15m
Delta
Deal found 6/9![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:20 pm
STL
- SAN
1 stop5h 50m
Southwest
Fri 7/316:55 pm
SAN
- STL
1 stop5h 00m
Southwest
Deal found 6/6![Southwest logo]()
$297
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:00 am
STL
- SAN
2 stops10h 26m
United Airlines
Wed 9/26:20 am
SAN
- STL
2 stops12h 26m
United Airlines
Deal found 6/10![United Airlines logo]()
$347
This Alaska Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:36 pm
STL
- SAN
1 stop17h 03m
Alaska Airlines
Mon 8/3110:12 am
SAN
- STL
2 stops11h 47m
Alaska Airlines
Deal found 6/10![Alaska Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:20 am
STL
- SAN
1 stop10h 21m
Delta
Mon 11/23:10 pm
SAN
- STL
1 stop6h 08m
Delta
Deal found 6/6![Delta logo]()
$307
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:50 pm
STL
- SAN
2 stops7h 40m
Southwest
Sat 9/56:20 am
SAN
- STL
2 stops7h 05m
Southwest
Deal found 6/10![Southwest logo]()
$324
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:55 pm
STL
- SAN
1 stop9h 58m
Delta
Sun 9/209:45 pm
SAN
- STL
1 stop9h 10m
Delta
Deal found 6/9![Delta logo]()
$318
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:45 am
STL
- SAN
1 stop6h 15m
Southwest
Sat 12/129:05 am
SAN
- STL
Nonstop3h 30m
Southwest
Deal found 6/8![Southwest logo]()
$347
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1712:59 pm
STL
- SAN
2 stops8h 56m
United Airlines
Fri 8/2110:40 pm
SAN
- STL
1 stop9h 32m
United Airlines
Deal found 6/8![United Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/289:30 am
STL
- SAN
2 stops13h 15m
United Airlines
Mon 8/316:20 am
SAN
- STL
2 stops12h 26m
United Airlines
Deal found 6/8![United Airlines logo]()
$407
Last-minute flights from St. Louis to San DiegoDiscover last-minute flight deals from St. Louis to San Diego. Data last updated June 11, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to San Diego. Data last updated June 11, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:38 pm
STL
- SAN
1 stop6h 15m
Frontier
Sat 7/1110:00 am
SAN
- STL
1 stop7h 23m
Frontier
Deal found 6/6![Frontier logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/292:56 pm
STL
- SAN
1 stop19h 52m
Frontier
Tue 7/144:12 pm
SAN
- STL
2 stops23h 53m
Frontier
Deal found 6/6![Frontier logo]()
$305
This Frontier deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:08 pm
STL
- SAN
1 stop5h 45m
Frontier
Thu 7/96:25 am
SAN
- STL
1 stop10h 58m
Frontier
Deal found 6/6![Frontier logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:46 pm
STL
- SAN
1 stop15h 05m
Frontier
Wed 7/83:03 pm
SAN
- STL
1 stop25h 12m
Frontier
Deal found 6/6![Frontier logo]()
$285
This CheapOair deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Mon 7/138:51 pm
SAN
- STL
1 stop19h 14m
Frontier
Deal found 6/9![Frontier logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:03 pm
STL
- SAN
1 stop21h 05m
Frontier
Tue 7/217:46 pm
SAN
- STL
2 stops44h 29m
Frontier
Deal found 6/8![Frontier logo]()
$286
This Frontier deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Sun 7/196:35 am
SAN
- STL
1 stop6h 21m
Frontier
Deal found 6/9![Frontier logo]()
$303
This Expedia deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Sun 7/198:51 pm
SAN
- STL
1 stop19h 24m
Frontier
Deal found 6/10![Frontier logo]()
$283
This CheapOair deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Wed 7/293:03 pm
SAN
- STL
1 stop25h 12m
Frontier
Deal found 6/11![Frontier logo]()
$289
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/244:45 pm
STL
- SAN
2 stops6h 20m
Southwest
Tue 7/288:30 am
SAN
- STL
1 stop7h 15m
Southwest
Deal found 6/10![Southwest logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:10 pm
STL
- SAN
1 stop20h 58m
Frontier
Fri 7/316:25 am
SAN
- STL
1 stop10h 58m
Frontier
Deal found 6/7![Frontier logo]()
$287
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:55 pm
STL
- SAN
1 stop5h 55m
Delta
Wed 8/511:30 am
SAN
- STL
1 stop7h 12m
Delta
Deal found 6/7![Delta logo]()
$297
One-way flights from St. Louis to San DiegoSearch for one-way flight options from St. Louis to San Diego. Find affordable one-way fares based on user searches. Data last updated June 11, 2026.
Search for one-way flight options from St. Louis to San Diego. Find affordable one-way fares based on user searches. Data last updated June 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/42:56 pm
STL
- SAN
1 stop6h 38m
Frontier
Deal found 6/10![Frontier logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/67:10 pm
STL
- SAN
1 stop20h 58m
Frontier
Deal found 6/8![Frontier logo]()
$95
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:35 am
STL
- SAN
1 stop7h 25m
Southwest
Deal found 6/8![Southwest logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:10 pm
STL
- SAN
1 stop20h 58m
Frontier
Deal found 6/10![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:08 pm
STL
- SAN
1 stop14h 34m
Frontier
Deal found 6/8![Frontier logo]()
$117
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:39 pm
STL
- SAN
1 stop7h 19m
Delta
Deal found 6/10![Delta logo]()
$119
This Frontier deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Deal found 6/10![Frontier logo]()
$120
This Trip.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:03 pm
STL
- SAN
1 stop21h 05m
Frontier
Deal found 6/6![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:08 pm
STL
- SAN
1 stop15h 02m
Frontier
Deal found 6/6![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/9![Frontier logo]()
$123
This Super.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/9![Frontier logo]()
$125
Find flight deals from St. Louis to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $272 (Frontier) |
One-way from | $94 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $429 |
Good round-trip deal | $502 or less |
Good one-way deal | $268 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
Use the filters below to find and compare flights from St. Louis to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Thu 9/3
2:10 pm-10:16 pm
1 stop10h 06m
San Diego
Mon 9/7
11:48 am-10:03 pm
1 stop8h 15m
$297
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Fri 7/24
7:20 pm-11:10 pm
1 stop5h 50m
San Diego
Fri 7/31
6:55 pm-1:55 am
1 stop5h 00m
$297
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Thu 10/29
7:20 am-3:41 pm
1 stop10h 21m
San Diego
Mon 11/2
3:10 pm-11:18 pm
1 stop6h 08m
$307
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Thu 9/17
1:55 pm-9:53 pm
1 stop9h 58m
San Diego
Sun 9/20
9:45 pm-8:55 am
1 stop9h 10m
$318
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Tue 9/1
2:50 pm-8:30 pm
2 stops7h 40m
San Diego
Sat 9/5
6:20 am-3:25 pm
2 stops7h 05m
$324
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Tue 9/1
9:00 am-5:26 pm
2 stops10h 26m
San Diego
Wed 9/2
6:20 am-8:46 pm
2 stops12h 26m
$347
Quickest round-trip
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Sat 12/5
8:45 am-1:00 pm
1 stop6h 15m
San Diego
Sat 12/12
9:05 am-2:35 pm
Nonstop3h 30m
$347
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Mon 8/17
12:59 pm-7:55 pm
2 stops8h 56m
San Diego
Fri 8/21
10:40 pm-10:12 am
1 stop9h 32m
$402
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Fri 8/28
7:36 pm-10:39 am
1 stop17h 03m
San Diego
Mon 8/31
10:12 am-11:59 pm
2 stops11h 47m
$405
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Fri 8/28
9:30 am-8:45 pm
2 stops13h 15m
San Diego
Mon 8/31
6:20 am-8:46 pm
2 stops12h 26m
$407
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from St. Louis to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to San Diego in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from St. Louis with our price prediction graph.
STL-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to San Diego
Prices
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How far ahead should I book a flight from St. Louis to San Diego?
To ensure you get the cheapest price possible for a flight from St. Louis to San Diego, you should look to book at least 35 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from St. Louis to San Diego?
Currently, September is the cheapest month in which you can book a flight from St. Louis to San Diego (average of $339). Flying from St. Louis to San Diego in December is currently the most expensive (average of $467). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from STL to SAN?
Find hourly flight availability from St. Louis to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 11, 2026.
Unlike at noon, when flights are generally more expensive, you can save up to 25% on flights from St. Louis to San Diego by exploring options for tickets in the afternoon.
What’s the top layover airport for flights from St. Louis to San Diego?
Share of 1-stop round-trip flights from St. Louis to San Diego chosen by Cheapflights users in the past 12 months, using the same layover each way.
Salt Lake City (SLC) – chosen by Cheapflights users on 50% of 1-stop itineraries from St. Louis to San Diego on Cheapflights.
What’s the cheapest layover airport for flights from St. Louis to San Diego?
Average round-trip fare for 1-stop flights from St. Louis to San Diego, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Denver (DEN) is the most affordable 1-stop option, with an average round-trip price of $312.
What’s the fastest layover option from St. Louis to San Diego?
Shortest average travel time for 1-stop one-way flights from St. Louis to San Diego, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Salt Lake City (SLC) have the shortest average one-way travel time for 1-stop routes: 6h 19m.
Which airport typically offers the quickest layover for flights from St. Louis to San Diego?
Average layover duration for 1-stop one-way flights from St. Louis to San Diego, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Salt Lake City (SLC) offer the fastest connection on this route, with an average layover time of 0h 53m.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated June 11, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from St. Louis to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from St. Louis to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
Poway
Coronado
La Mesa
Santee
Julian
Lemon Grove
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St. Louis and San Diego flights
Browse other St. Louis and San Diego flight options. Last updated on June 11, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on June 11, 2026.
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Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 11, 2026.
Top 5 airlines flying from St. Louis to San Diego
Discover the top 5 airlines that operate flights from St. Louis to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$88 | Average$244 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$182 | Average$334 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$211 | Average$400 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$222 | Average$357 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$289 | Average$455 | FlexibilityNo cancel fee | On-time63% |