$408+ Cheap flights from St. Louis (STL) to Sao Paulo, Brazil (SAO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SAO
Nov 24 — Dec 11
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Sao Paulo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Sao Paulo
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to Sao PauloExplore the most affordable flight options available from St. Louis to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from St. Louis to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This Mytrip deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:20 pm -
3 stops32h 00m
Wed 12/99:45 pm -
2 stops44h 41m
Deal found 10/24![Multiple Airlines logo]()
$1,092
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:26 pm -
1 stop13h 24m
Fri 11/1311:10 am -
2 stops39h 06m
Deal found 10/20![Multiple Airlines logo]()
$1,209
This Booking.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:05 pm -
2 stops39h 20m
Fri 11/139:45 pm -
2 stops44h 41m
Deal found 10/20![Air Canada logo]()
$1,211
This Mytrip deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:20 pm -
3 stops42h 55m
Sun 12/139:55 pm -
3 stops29h 17m
Deal found 10/22![Multiple Airlines logo]()
$1,221
This Air Canada deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:05 pm -
2 stops37h 55m
Wed 12/99:45 pm -
2 stops44h 41m
Deal found 10/24![Air Canada logo]()
$1,238
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:20 pm -
2 stops35h 00m
Wed 12/165:20 am -
1 stop15h 54m
Deal found 10/24![Multiple Airlines logo]()
$1,253
This Ovago deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:00 am -
2 stops22h 30m
Mon 11/231:40 am -
2 stops23h 00m
Deal found 10/20![Copa Airlines logo]()
$1,255
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:20 am -
2 stops17h 30m
Tue 11/2411:10 am -
1 stop29h 14m
Deal found 10/20![Multiple Airlines logo]()
$1,284
Best flights from St. Louis to Sao PauloDiscover carefully curated flight deals from St. Louis to Sao Paulo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from St. Louis to Sao Paulo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:26 pm -
1 stop13h 24m
Fri 11/1311:10 am -
2 stops39h 06m
Deal found 10/20![Multiple Airlines logo]()
$1,209
This Air Canada deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/294:05 pm -
2 stops39h 45m
Wed 3/318:55 pm -
2 stops20h 31m
Deal found 10/21![Air Canada logo]()
$1,372
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1110:30 am -
2 stops17h 40m
Sat 3/2010:15 pm -
1 stop16h 00m
Deal found 10/24![United Airlines logo]()
$1,374
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1110:25 am -
2 stops16h 55m
Fri 3/1912:05 am -
2 stops18h 05m
Deal found 10/24![American Airlines logo]()
$1,379
This GOL deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1212:03 pm -
1 stop18h 22m
Thu 1/2111:10 pm -
1 stop21h 16m
Deal found 10/20![GOL logo]()
$1,399
This Mytrip deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:20 pm -
3 stops42h 55m
Sun 12/139:55 pm -
3 stops29h 17m
Deal found 10/22![Multiple Airlines logo]()
$1,221
This Booking.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/124:05 pm -
2 stops39h 20m
Sat 3/209:45 pm -
2 stops43h 41m
Deal found 10/24![Air Canada logo]()
$1,407
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:20 am -
2 stops17h 30m
Tue 11/2411:10 am -
1 stop29h 14m
Deal found 10/20![Multiple Airlines logo]()
$1,284
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/129:40 am -
1 stop18h 35m
Sat 3/2010:15 pm -
1 stop18h 02m
Deal found 10/24![United Airlines logo]()
$1,414
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1210:23 am -
1 stop19h 07m
Sun 3/2110:35 pm -
1 stop20h 54m
Deal found 10/24![American Airlines logo]()
$1,414
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/610:35 am -
1 stop18h 00m
Sun 12/1310:35 pm -
1 stop14h 30m
Deal found 10/22![American Airlines logo]()
$1,449
Last-minute flights from St. Louis to Sao PauloDiscover last-minute flight deals from St. Louis to Sao Paulo. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Sao Paulo. Data last updated October 25, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:26 pm -
1 stop13h 24m
Fri 11/1311:10 am -
2 stops39h 06m
Deal found 10/20![Multiple Airlines logo]()
$1,209
This Booking.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:05 pm -
2 stops39h 20m
Fri 11/139:45 pm -
2 stops44h 41m
Deal found 10/20![Air Canada logo]()
$1,211
This Ovago deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:00 am -
2 stops22h 30m
Mon 11/231:40 am -
2 stops23h 00m
Deal found 10/20![Copa Airlines logo]()
$1,255
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:20 am -
2 stops17h 30m
Tue 11/2411:10 am -
1 stop29h 14m
Deal found 10/20![Multiple Airlines logo]()
$1,284
This Mytrip deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:20 pm -
3 stops32h 00m
Wed 12/99:45 pm -
2 stops44h 41m
Deal found 10/24![Multiple Airlines logo]()
$1,092
This Air Canada deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:05 pm -
2 stops37h 55m
Wed 12/99:45 pm -
2 stops44h 41m
Deal found 10/24![Air Canada logo]()
$1,238
One-way flights from St. Louis to Sao PauloSearch for one-way flight options from St. Louis to Sao Paulo. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from St. Louis to Sao Paulo. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:35 pm -
3 stops30h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$408
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:21 pm -
3 stops34h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$489
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/286:21 pm -
3 stops58h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$512
Find flight deals from St. Louis to Sao Paulo
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Sao Paulo (SAO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $1,092 (Mytrip) |
One-way from | $408 (Kiwi.com) |
Popular in | February |
Cheapest in | September |
Average price | $1,331 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from St. Louis to Sao Paulo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSao Paulo
STL Lambert-St Louis - GRU Sao Paulo Guarulhos Intl
STLGRU
Lambert-St Louis
Mon 11/23
1:20 pm-10:40 pm
2 stops30h 20m
Sao Paulo Guarulhos Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$528
St. LouisSao Paulo
STL Lambert-St Louis - GRU Sao Paulo Guarulhos Intl
STLGRU
Lambert-St Louis
Tue 12/29
5:58 pm-8:20 am
2 stops35h 22m
Sao Paulo Guarulhos Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$548
St. LouisSao Paulo
STL Lambert-St Louis - GRU Sao Paulo Guarulhos Intl
STLGRU
Lambert-St Louis
Sun 12/27
5:58 pm-3:35 am
2 stops30h 37m
Sao Paulo Guarulhos Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$657
St. LouisSao Paulo
STL Lambert-St Louis - GRU Sao Paulo Guarulhos Intl
STLGRU
Lambert-St Louis
Thu 12/31
6:00 am-2:50 am
2 stops17h 50m
Sao Paulo Guarulhos Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$666
St. LouisSao Paulo
STL Lambert-St Louis - GRU Sao Paulo Guarulhos Intl
STLGRU
Lambert-St Louis
Sat 12/26
5:58 pm-8:20 am
2 stops35h 22m
Sao Paulo Guarulhos Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$825
St. LouisSao Paulo
STL Lambert-St Louis - GRU Sao Paulo Guarulhos Intl
STLGRU
Lambert-St Louis
Wed 11/25
10:05 am-9:35 am
1 stop20h 30m
Sao Paulo Guarulhos Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$836
St. LouisSao Paulo
STL Lambert-St Louis - GRU Sao Paulo Guarulhos Intl
STLGRU
Lambert-St Louis
Wed 11/25
10:37 am-6:20 am
1 stop16h 43m
Sao Paulo Guarulhos Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$876
Quickest round-trip
St. LouisSao Paulo
STL Lambert-St Louis - GRU Sao Paulo Guarulhos Intl
STLGRU
Lambert-St Louis
Tue 12/29
12:06 pm-7:35 am
1 stop16h 29m
Sao Paulo Guarulhos Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$878
St. LouisSao Paulo
STL Lambert-St Louis - GRU Sao Paulo Guarulhos Intl
STLGRU
Lambert-St Louis
Fri 11/6
4:26 pm-8:50 am
1 stop13h 24m
Sao Paulo Guarulhos Intl
Fri 11/13
11:10 am-11:16 pm
2 stops39h 06m
$1,209
St. LouisSao Paulo
STL Lambert-St Louis - GRU Sao Paulo Guarulhos Intl
STLGRU
Lambert-St Louis
Sun 12/6
6:20 pm-4:15 pm
3 stops42h 55m
Sao Paulo Guarulhos Intl
Sun 12/13
9:55 pm-12:12 am
3 stops29h 17m
$1,221
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Sao Paulo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Sao Paulo in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Sao Paulo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Sao Paulo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Sao Paulo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Sao Paulo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Sao Paulo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Sao Paulo
Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from St. Louis with our price prediction graph.
STL-SAO
STL-GRU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Sao Paulo
STL-SAO
STL-GRU
What is the cheapest month to book a flight from St. Louis to Sao Paulo?
Currently, September is the cheapest month in which you can book a flight from St. Louis to Sao Paulo (average of $835). Flying from St. Louis to Sao Paulo in June is currently the most expensive (average of $1,651). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Sao Paulo?
Airfare is below average for this route at the moment.
St. Louis to Sao Paulo flights typically cost between $1,366 and $1,562 in November.The cheapest round-trip price found within the last 5 days was $1,092 on Multiple Airlines (Nov 25-Dec 9).
Reviews of airlines servicing Sao Paulo
Get insights into the airlines that provide service to Sao Paulo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sao Paulo. Reviews last updated October 25, 2026.
Read through reviews of airlines operating flights from St. Louis to Sao Paulo, such as Delta,Air Canada, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Sao Paulo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Sao Paulo?
Book flights to Sao Paulo if you plan to visit one of these locationsSantos
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from St. Louis
Popular flights
Sao Paulo flight routes
Alternative routes for St. Louis to Sao Paulo
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Sao Paulo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Sao Paulo by cabin class
Find flights from St. Louis to Sao Paulo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Sao Paulo flights
Browse other St. Louis and Sao Paulo flight options. Last updated on October 25, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Sao Paulo
Explore flights to Sao Paulo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Top 3 airlines flying from St. Louis to Sao Paulo
Discover the top 3 airlines that operate flights from St. Louis to Sao Paulo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$1,064 | Average$1,362 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$1,188 | Average$1,397 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$1,292 | Average$1,471 | FlexibilityNo cancel fee | On-time69% |