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South America

$217+ Cheap flights from St. Louis (STL) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BOG
mar. 26 — abr. 21
mié. 3/26
mié. 4/2
1 adult, Economy
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Cheap flight deals from St. Louis to South America

Keep the following information in mind while searching for St. Louis to South America flight deals. Data was last updated marzo 21, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$420
(CheapOair)

One-way from

$217
(Avianca)

Popular in

June

Cheapest in

May

Average price

$907
Provider with most accurate pricing for Lambert-St Louis-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Sao Paulo (SAO) flights.
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From Lambert-St Louis to South America
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One-way flight from Lambert-St Louis to South America
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High demand for flights, 2% potential price rise
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Cheapest flight prices on average. 0% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from St. Louis to South America

Cheapest flights from St. Louis to South America
Explore the most affordable flight options available from St. Louis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 21, 2025.

This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/66:10 pmSTL - MDE
1 stop19h 05mSpirit Airlines
sáb. 5/102:13 pmMDE - STL
1 stop19h 02mSpirit Airlines
Deal found 3/20$420
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/26:00 amSTL - BOG
2 stops21h 15mDelta
mar. 4/85:00 amBOG - STL
2 stops18h 29mDelta
Deal found 3/20$475
This LATAM Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/2810:42 amSTL - BOG
1 stop8h 33mLATAM Airlines
vie. 5/309:00 amBOG - STL
1 stop9h 01mLATAM Airlines
Deal found 3/20$485
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/237:04 amSTL - BOG
1 stop15h 26mAmerican Airlines
dom. 4/276:30 amBOG - STL
1 stop15h 44mAmerican Airlines
Deal found 3/20$529
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/246:10 pmSTL - CTG
1 stop17h 57mMultiple Airlines
dom. 4/279:55 pmCTG - STL
2 stops43h 20mMultiple Airlines
Deal found 3/21$561
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/206:00 amSTL - MDE
1 stop15h 10mUnited Airlines
mar. 6/109:45 amMDE - STL
1 stop12h 30mUnited Airlines
Deal found 3/20$566
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/205:12 amSTL - CTG
2 stops8h 58mAmerican Airlines
mar. 6/101:25 pmCTG - STL
2 stops18h 48mAmerican Airlines
Deal found 3/20$579
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/2410:42 amSTL - CTG
2 stops12h 02mDelta
dom. 4/276:42 amCTG - STL
2 stops16h 59mDelta
Deal found 3/21$591
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/315:35 pmSTL - BOG
2 stops25h 45mUnited Airlines
dom. 4/2012:14 amBOG - STL
1 stop21h 55mUnited Airlines
Deal found 3/19$611
This Avianca Connect deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/3110:10 amSTL - BOG
1 stop7h 49mMultiple Airlines
mar. 7/19:00 amBOG - STL
1 stop9h 32mMultiple Airlines
Deal found 3/20$624
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/2110:05 amSTL - MDE
2 stops11h 46mDelta
dom. 5/2510:47 amMDE - STL
2 stops12h 51mDelta
Deal found 3/20$648
This LATAM Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/207:05 amSTL - CTG
1 stop6h 14mLATAM Airlines
mar. 6/102:06 pmCTG - STL
1 stop18h 00mLATAM Airlines
Deal found 3/20$653

Cheapflights Fare Finder

Customize your flight search to find flights from St. Louis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 21, 2025.
Use the filters below to find and compare flights from St. Louis to South America that are best for you.

Fly from

St. Louis

Fly to

South America

Route

Depart

Return

Price

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

mar. 5/6

6:10 pm-1:15 pm

1 stop19h 05m

Medellín Jose Maria Cordova Intl

sáb. 5/10

2:13 pm-9:15 am

1 stop19h 02m

$420

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

mié. 4/2

6:00 am-3:15 am

2 stops21h 15m

Bogotá El Dorado

mar. 4/8

5:00 am-11:29 pm

2 stops18h 29m

$475

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

lun. 4/28

5:26 am-10:30 pm

1 stop17h 04m

Bogotá El Dorado

jue. 5/29

12:25 am-4:22 pm

1 stop15h 57m

$485

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

lun. 4/28

6:00 am-7:58 pm

2 stops13h 58m

Bogotá El Dorado

vie. 5/30

7:00 am-6:01 pm

2 stops11h 01m

$489

St. LouisCartagena

STL - CTG

STLCTG

Lambert-St Louis

jue. 4/24

6:10 pm-12:07 pm

1 stop17h 57m

Cartagena Rafael Nunez

dom. 4/27

9:55 pm-5:15 pm

2 stops43h 20m

$561

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

mar. 5/20

6:00 am-9:10 pm

1 stop15h 10m

Medellín Jose Maria Cordova Intl

lun. 6/9

12:15 am-10:39 am

1 stop10h 24m

$566

St. LouisCartagena

STL - CTG

STLCTG

Lambert-St Louis

mar. 5/20

5:13 am-12:25 pm

1 stop7h 12m

Cartagena Rafael Nunez

mar. 6/10

1:25 pm-8:46 am

2 stops19h 21m

$579

St. LouisCartagena

STL - CTG

STLCTG

Lambert-St Louis

jue. 4/24

10:42 am-10:44 pm

2 stops12h 02m

Cartagena Rafael Nunez

dom. 4/27

6:42 am-11:41 pm

2 stops16h 59m

$591

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

lun. 3/31

5:35 pm-7:20 pm

2 stops25h 45m

Bogotá El Dorado

dom. 4/20

12:14 am-10:09 pm

1 stop21h 55m

$611

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

sáb. 5/31

10:10 am-5:59 pm

1 stop7h 49m

Bogotá El Dorado

mar. 7/1

9:00 am-6:32 pm

1 stop9h 32m

$624

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/20

Showing 1-10 of 48 results
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Best time to book a flight from St. Louis to South America

Have a flexible travel schedule? Discover the best time to fly to South America from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to South America

What is the cheapest month to book a flight from St. Louis to South America?

Currently, May is the cheapest month in which you can book a flight from St. Louis to South America (average of $359). Flying from St. Louis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to SA?

Find hourly flight availability from St. Louis to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated marzo 21, 2025.

When flying from St. Louis to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated marzo 21, 2025.
Delta
8.0
Very good
7,895 reviews

Boarding

8.2

Food

7.3

Comfort

8.0

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,895 reviews
Delta
8.0
Very good
7,895 reviews

Boarding

8.2

Food

7.3

Comfort

8.0

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,400 reviews
Delta
8.0
Very good
7,895 reviews

Boarding

8.2

Food

7.3

Comfort

8.0

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,750 reviews
Delta
8.0
Very good
7,895 reviews

Boarding

8.2

Food

7.3

Comfort

8.0

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,605 reviews
Delta
8.0
Very good
7,895 reviews

Boarding

8.2

Food

7.3

Comfort

8.0

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,895 reviews

Boarding

8.2

Food

7.3

Comfort

8.0

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to South America?

    Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to South America from St. Louis.

  • What are the cheapest airlines to fly from St. Louis to South America one-way?

    $297 is the cheapest one-way deal found within the past few days, from Copa Airlines. You may also be able to find cheap deals on Delta and LATAM Airlines, with prices starting from $323 and $329, respectively.

  • What are the most popular routes from St. Louis to South America?

    The most popular flight routes from St. Louis to South America are Lambert-St Louis - Lima J Chavez Intl, Lambert-St Louis - Medellín Jose Maria Cordova Intl and Lambert-St Louis - Bogotá El Dorado.

  • Can I find deals for flights from St. Louis to South America that include hotel bookings?

    Yes. In addition to deals on St. Louis to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to South America.

  • Can I find deals for business class flights from St. Louis to South America?

    Yes. Cheapflights offers flight deals from St. Louis to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to South America?

    Currently, May is the cheapest month in which you can book a flight from St. Louis to South America (average of $359). Flying from St. Louis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from St. Louis to South America

Discover the top 5 airlines that operate flights from St. Louis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$273Average$396FlexibilityNo cancel feeOn-time65%
DeltaCheapest$289Average$893FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$389Average$885FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$399Average$894FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$463Average$887FlexibilityNo cancel feeOn-time71%
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