$201+ Cheap flights from St. Louis (STL) to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/30. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BOG
Nov 21 — Nov 281
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to South America
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Cheapest flights from St. Louis to South AmericaExplore the most affordable flight options available from St. Louis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
Explore the most affordable flight options available from St. Louis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
This LATAM Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop12h 30m
Mon 11/163:55 pm -
1 stop9h 01m
Deal found 10/20![LATAM Airlines logo]()
$622
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:00 am -
1 stop16h 22m
Fri 12/117:50 am -
1 stop14h 59m
Deal found 10/21![American Airlines logo]()
$623
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/24:48 pm -
1 stop18h 46m
Wed 12/911:55 pm -
1 stop15h 00m
Deal found 10/18![American Airlines logo]()
$635
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:00 am -
2 stops16h 35m
Fri 12/118:15 am -
2 stops15h 44m
Deal found 10/18![United Airlines logo]()
$662
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:15 pm -
1 stop17h 19m
Fri 12/111:40 pm -
1 stop9h 09m
Deal found 10/20![American Airlines logo]()
$666
This LATAM Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2410:05 am -
1 stop10h 20m
Thu 12/38:55 am -
2 stops16h 10m
Deal found 10/20![LATAM Airlines logo]()
$676
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:15 am -
1 stop17h 15m
Wed 12/21:35 am -
1 stop13h 41m
Deal found 10/20![United Airlines logo]()
$698
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/258:30 am -
2 stops15h 00m
Thu 12/31:35 am -
2 stops11h 47m
Deal found 10/19![United Airlines logo]()
$702
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:18 pm -
1 stop25h 07m
Mon 11/3012:55 am -
1 stop11h 34m
Deal found 10/19![Delta logo]()
$706
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:50 pm -
2 stops28h 40m
Sun 11/291:35 am -
1 stop21h 50m
Deal found 10/20![United Airlines logo]()
$729
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:00 am -
1 stop16h 36m
Mon 11/1612:55 am -
1 stop15h 55m
Deal found 10/19![American Airlines logo]()
$738
This Justfly.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:31 pm -
1 stop13h 29m
Tue 12/812:10 pm -
1 stop12h 55m
Deal found 10/21![LATAM Airlines logo]()
$740
Best flights from St. Louis to South AmericaDiscover carefully curated flight deals from St. Louis to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
Discover carefully curated flight deals from St. Louis to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:00 am -
1 stop16h 22m
Fri 12/117:50 am -
2 stops15h 30m
Deal found 10/22![American Airlines logo]()
$627
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/166:00 am -
1 stop7h 25m
Sat 1/234:10 pm -
2 stops19h 38m
Deal found 10/19![Delta logo]()
$653
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:00 am -
2 stops16h 35m
Fri 12/118:15 am -
2 stops15h 44m
Deal found 10/18![United Airlines logo]()
$662
This FlightHub deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/17:02 pm -
2 stops39h 58m
Mon 3/11:10 pm -
1 stop11h 54m
Deal found 10/17![Frontier logo]()
$694
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/168:30 am -
2 stops14h 50m
Sat 1/236:10 am -
2 stops14h 17m
Deal found 10/19![Copa Airlines logo]()
$754
This Travelocity deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/144:05 pm -
1 stop13h 05m
Thu 1/218:00 am -
2 stops32h 26m
Deal found 10/17![Air Canada logo]()
$758
This Avianca deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/16:45 pm -
2 stops15h 50m
Fri 2/59:30 am -
2 stops25h 38m
Deal found 10/18![Avianca logo]()
$866
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:58 pm -
1 stop19h 07m
Tue 1/56:25 pm -
2 stops48h 13m
Deal found 10/20![Multiple Airlines logo]()
$1,001
This LATAM Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/209:00 am -
2 stops30h 00m
Sat 3/69:50 pm -
1 stop13h 22m
Deal found 10/20![LATAM Airlines logo]()
$1,138
This GOL deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/293:45 pm -
2 stops16h 50m
Mon 2/810:30 pm -
1 stop15h 22m
Deal found 10/21![GOL logo]()
$1,294
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:25 am -
2 stops10h 56m
Wed 12/97:50 am -
2 stops15h 20m
Deal found 10/18![American Airlines logo]()
$696
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:15 am -
1 stop17h 15m
Wed 12/21:35 am -
1 stop13h 41m
Deal found 10/20![United Airlines logo]()
$698
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/115:30 pm -
2 stops24h 22m
Tue 3/1611:45 pm -
1 stop14h 58m
Deal found 10/17![Delta logo]()
$702
This Frontier deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/17:02 pm -
2 stops15h 58m
Fri 2/51:10 pm -
1 stop11h 54m
Deal found 10/19![Frontier logo]()
$703
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:40 am -
2 stops13h 50m
Tue 12/11:35 am -
2 stops14h 06m
Deal found 10/19![United Airlines logo]()
$702
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:58 pm -
2 stops23h 22m
Mon 11/93:20 pm -
2 stops20h 33m
Deal found 10/22![American Airlines logo]()
$741
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/105:59 pm -
1 stop29h 31m
Thu 3/111:35 am -
1 stop16h 09m
Deal found 10/17![United Airlines logo]()
$708
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:02 am -
2 stops14h 44m
Wed 12/97:00 am -
2 stops13h 58m
Deal found 10/18![American Airlines logo]()
$751
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:03 am -
1 stop13h 17m
Tue 12/2912:05 pm -
1 stop13h 41m
Deal found 10/21![Delta logo]()
$856
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/141:17 pm -
2 stops34h 13m
Tue 3/1612:35 am -
2 stops16h 34m
Deal found 10/17![United Airlines logo]()
$719
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:21 am -
1 stop12h 06m
Sun 11/228:00 am -
1 stop14h 50m
Deal found 10/22![American Airlines logo]()
$758
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:18 pm -
1 stop25h 02m
Wed 11/2512:15 am -
2 stops20h 54m
Deal found 10/18![Delta logo]()
$865
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/67:04 pm -
2 stops28h 26m
Tue 3/2312:35 am -
1 stop9h 12m
Deal found 10/21![United Airlines logo]()
$727
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:15 pm -
1 stop19h 09m
Thu 12/107:00 am -
1 stop11h 25m
Deal found 10/19![American Airlines logo]()
$761
This Air Canada deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/234:05 pm -
2 stops37h 55m
Fri 12/111:45 pm -
2 stops28h 41m
Deal found 10/20![Multiple Airlines logo]()
$1,121
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:50 pm -
2 stops28h 40m
Mon 11/301:35 am -
1 stop21h 55m
Deal found 10/18![United Airlines logo]()
$729
This LATAM Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/43:40 pm -
2 stops22h 00m
Mon 3/89:05 pm -
1 stop16h 43m
Deal found 10/20![LATAM Airlines logo]()
$1,223
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:15 pm -
1 stop17h 45m
Wed 12/1612:10 pm -
1 stop12h 55m
Deal found 10/22![Delta logo]()
$920
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:26 pm -
1 stop13h 24m
Fri 11/1311:10 am -
2 stops39h 06m
Deal found 10/20![Multiple Airlines logo]()
$1,209
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:15 am -
1 stop14h 55m
Wed 12/3010:40 am -
1 stop12h 50m
Deal found 10/21![United Airlines logo]()
$769
Last-minute flights from St. Louis to South AmericaDiscover last-minute flight deals from St. Louis to South America. Data last updated October 22, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to South America. Data last updated October 22, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:00 am -
1 stop8h 15m
Thu 10/292:15 pm -
2 stops20h 36m
Deal found 10/19![American Airlines logo]()
$751
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:58 pm -
2 stops23h 22m
Mon 11/93:20 pm -
2 stops20h 33m
Deal found 10/21![American Airlines logo]()
$741
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:00 am -
1 stop16h 36m
Mon 11/1612:55 am -
1 stop15h 55m
Deal found 10/19![American Airlines logo]()
$738
This LATAM Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop12h 30m
Mon 11/163:55 pm -
1 stop9h 01m
Deal found 10/20![LATAM Airlines logo]()
$622
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:18 pm -
1 stop25h 07m
Mon 11/3012:55 am -
1 stop11h 34m
Deal found 10/19![Delta logo]()
$706
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:50 pm -
2 stops28h 40m
Sun 11/291:35 am -
1 stop21h 50m
Deal found 10/20![United Airlines logo]()
$729
This Justfly.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:31 pm -
1 stop13h 29m
Tue 12/812:10 pm -
1 stop12h 55m
Deal found 10/21![LATAM Airlines logo]()
$740
This LATAM Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2410:05 am -
1 stop10h 20m
Thu 12/38:55 am -
2 stops16h 10m
Deal found 10/20![LATAM Airlines logo]()
$676
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:15 am -
1 stop17h 15m
Wed 12/21:35 am -
1 stop13h 41m
Deal found 10/20![United Airlines logo]()
$698
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/258:30 am -
2 stops15h 00m
Thu 12/31:35 am -
2 stops11h 47m
Deal found 10/19![United Airlines logo]()
$702
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:00 am -
1 stop16h 22m
Fri 12/117:50 am -
1 stop14h 59m
Deal found 10/21![American Airlines logo]()
$623
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:00 am -
2 stops16h 35m
Fri 12/118:15 am -
2 stops15h 44m
Deal found 10/18![United Airlines logo]()
$662
One-way flights from St. Louis to South AmericaSearch for one-way flight options from St. Louis to South America. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
Search for one-way flight options from St. Louis to South America. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
This Priceline deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/305:58 pm -
1 stop16h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Frontier logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:21 pm -
3 stops28h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:15 pm -
3 stops32h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$327
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:13 pm -
3 stops52h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:34 pm -
3 stops36h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:34 pm -
3 stops27h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/98:45 pm -
2 stops26h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:20 pm -
3 stops57h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:14 pm -
3 stops25h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$366
This Copa Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:00 am -
2 stops26h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Copa Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:14 pm -
3 stops30h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$392
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/811:06 am -
3 stops27h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$405
Find flight deals from St. Louis to South America
Keep the following information in mind while searching for St. Louis to South America flight deals. Data was last updated October 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $551 (FlightHub) |
One-way from | $201 (Priceline) |
Popular in | February |
Cheapest in | September |
Average price | $1,331 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
Use the filters below to find and compare flights from St. Louis to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisLima
STL Lambert-St Louis - LIM Lima J Chavez Intl
STLLIM
Lambert-St Louis
Sat 11/21
5:15 pm-2:31 am
3 stops32h 16m
Lima J Chavez Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$327
St. LouisMedellín
STL Lambert-St Louis - MDE Medellín Jose Maria Cordova Intl
STLMDE
Lambert-St Louis
Wed 11/18
6:34 pm-8:15 am
3 stops36h 41m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$334
St. LouisBogotá
STL Lambert-St Louis - BOG Bogotá El Dorado
STLBOG
Lambert-St Louis
Wed 12/30
5:58 pm-6:45 pm
1 stop23h 47m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$338
St. LouisLima
STL Lambert-St Louis - LIM Lima J Chavez Intl
STLLIM
Lambert-St Louis
Sat 1/9
8:45 pm-12:10 am
2 stops26h 25m
Lima J Chavez Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$349
St. LouisBogotá
STL Lambert-St Louis - BOG Bogotá El Dorado
STLBOG
Lambert-St Louis
Thu 11/12
12:14 pm-2:25 pm
3 stops25h 11m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$366
St. LouisBogotá
STL Lambert-St Louis - BOG Bogotá El Dorado
STLBOG
Lambert-St Louis
Fri 11/27
8:00 am-11:07 am
2 stops26h 07m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$367
St. LouisMedellín
STL Lambert-St Louis - MDE Medellín Jose Maria Cordova Intl
STLMDE
Lambert-St Louis
Thu 11/12
12:14 pm-7:40 pm
3 stops30h 26m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$392
St. LouisBogotá
STL Lambert-St Louis - BOG Bogotá El Dorado
STLBOG
Lambert-St Louis
Fri 11/27
5:00 am-10:22 pm
1 stop16h 22m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$405
St. LouisBogotá
STL Lambert-St Louis - BOG Bogotá El Dorado
STLBOG
Lambert-St Louis
Thu 11/12
10:21 am-11:30 pm
1 stop12h 09m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$405
St. LouisBogotá
STL Lambert-St Louis - BOG Bogotá El Dorado
STLBOG
Lambert-St Louis
Wed 11/18
7:00 am-10:20 pm
2 stops14h 20m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$405
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from St. Louis to South America
Have a flexible travel schedule? Discover the best time to fly to South America from St. Louis with our price prediction graph.
STL-BOG
STL-LIM
STL-MDE
STL-UIO
STL-CLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to South America
STL-0SA
STL-BOG
STL-LIM
STL-MDE
STL-UIO
What is the cheapest month to book a flight from St. Louis to South America?
Currently, September is the cheapest month in which you can book a flight from St. Louis to South America (average of $849). Flying from St. Louis to South America in December is currently the most expensive (average of $1,283). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from St. Louis to South America?
To ensure you get the cheapest price possible for a flight from St. Louis to South America, you should look to book at least 74 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated October 22, 2026.
Peruse reviews from past customers who have flown with Delta,LATAM Airlines, andUnited Airlines from St. Louis to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from St. Louis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for St. Louis to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to South America by cabin class
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St. Louis and South America flights
Browse other St. Louis and South America flight options. Last updated on October 22, 2026.
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Top 4 airlines flying from St. Louis to South America
Discover the top 4 airlines that operate flights from St. Louis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$431 | Average$1,092 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$536 | Average$1,007 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$563 | Average$1,006 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$615 | Average$1,082 | FlexibilityNo cancel fee | On-time69% |