$226+ Cheap flights from St. Louis (STL) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BOG
Aug 23 — Aug 301
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
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Cheapest flights from St. Louis to South AmericaExplore the most affordable flight options available from St. Louis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.
Explore the most affordable flight options available from St. Louis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:00 am
STL
- BOG
1 stop8h 05m
American Airlines
Sat 8/296:30 am
BOG
- STL
1 stop16h 10m
American Airlines
Deal found 7/22![American Airlines logo]()
$481
This LATAM Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 am
STL
- BOG
2 stops14h 10m
LATAM Airlines
Mon 8/242:55 pm
BOG
- STL
1 stop9h 03m
LATAM Airlines
Deal found 7/20![LATAM Airlines logo]()
$486
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:43 am
STL
- BOG
1 stop16h 47m
American Airlines
Tue 9/226:30 am
BOG
- STL
1 stop15h 19m
American Airlines
Deal found 7/21![American Airlines logo]()
$490
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/77:00 am
STL
- BOG
2 stops13h 10m
Delta
Mon 9/1411:00 am
BOG
- STL
2 stops12h 42m
Delta
Deal found 7/24![Delta logo]()
$506
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:20 am
STL
- BOG
2 stops13h 50m
Delta
Sat 8/2911:00 am
BOG
- STL
2 stops22h 37m
Delta
Deal found 7/22![Delta logo]()
$516
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:36 am
STL
- BOG
1 stop15h 58m
American Airlines
Sat 9/512:25 am
BOG
- STL
1 stop19h 26m
American Airlines
Deal found 7/19![American Airlines logo]()
$538
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:16 am
STL
- BOG
1 stop12h 18m
American Airlines
Mon 9/146:30 am
BOG
- STL
1 stop17h 29m
American Airlines
Deal found 7/24![American Airlines logo]()
$551
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:36 am
STL
- BOG
1 stop13h 58m
American Airlines
Mon 9/72:10 pm
BOG
- STL
1 stop20h 29m
American Airlines
Deal found 7/22![American Airlines logo]()
$557
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:11 pm
STL
- CTG
1 stop22h 24m
American Airlines
Tue 9/221:35 pm
CTG
- STL
1 stop8h 14m
American Airlines
Deal found 7/21![American Airlines logo]()
$577
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:00 am
STL
- CTG
1 stop9h 15m
American Airlines
Tue 8/183:15 pm
CTG
- STL
2 stops17h 09m
American Airlines
Deal found 7/20![American Airlines logo]()
$585
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:11 pm
STL
- CTG
2 stops19h 24m
American Airlines
Sat 9/121:35 pm
CTG
- STL
1 stop23h 46m
American Airlines
Deal found 7/22![American Airlines logo]()
$586
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:13 pm
STL
- CTG
2 stops19h 22m
American Airlines
Mon 9/281:35 pm
CTG
- STL
2 stops20h 54m
American Airlines
Deal found 7/20![American Airlines logo]()
$592
Best flights from St. Louis to South AmericaDiscover carefully curated flight deals from St. Louis to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 24, 2026.
Discover carefully curated flight deals from St. Louis to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 24, 2026.
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:00 am
STL
- BOG
1 stop8h 05m
American Airlines
Sat 8/296:30 am
BOG
- STL
1 stop16h 10m
American Airlines
Deal found 7/22![American Airlines logo]()
$481
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/77:00 am
STL
- BOG
2 stops13h 10m
Delta
Mon 9/1411:00 am
BOG
- STL
2 stops12h 42m
Delta
Deal found 7/24![Delta logo]()
$506
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:35 am
STL
- MDE
1 stop12h 35m
United Airlines
Mon 9/289:45 am
MDE
- STL
1 stop12h 45m
United Airlines
Deal found 7/21![United Airlines logo]()
$630
This FlightHub deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:58 pm
STL
- BOG
1 stop24h 17m
LATAM Airlines
Tue 8/42:55 pm
BOG
- STL
1 stop8h 26m
LATAM Airlines
Deal found 7/20![LATAM Airlines logo]()
$646
This Orbitz deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:55 am
STL
- CTG
2 stops26h 35m
Multiple Airlines
Mon 9/218:45 pm
CTG
- STL
2 stops41h 15m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$672
This Air Canada deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:05 pm
STL
- LIM
1 stop13h 05m
Air Canada
Wed 12/98:00 am
LIM
- STL
1 stop32h 26m
Air Canada
Deal found 7/23![Air Canada logo]()
$687
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:53 am
STL
- BOG
2 stops14h 24m
American Airlines
Tue 9/226:30 am
BOG
- STL
2 stops12h 37m
American Airlines
Deal found 7/21![American Airlines logo]()
$494
This GOL deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:20 pm
STL
- GIG
2 stops50h 50m
GOL
Mon 10/198:15 pm
GIG
- STL
2 stops23h 34m
GOL
Deal found 7/19![GOL logo]()
$1,018
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:20 am
STL
- BOG
2 stops13h 50m
Delta
Sat 8/2911:00 am
BOG
- STL
2 stops22h 37m
Delta
Deal found 7/22![Delta logo]()
$516
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:36 am
STL
- BOG
1 stop15h 58m
American Airlines
Sat 9/512:25 am
BOG
- STL
1 stop19h 26m
American Airlines
Deal found 7/19![American Airlines logo]()
$538
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:15 am
STL
- MDE
1 stop14h 55m
United Airlines
Wed 10/289:45 am
MDE
- STL
1 stop12h 35m
United Airlines
Deal found 7/23![United Airlines logo]()
$645
This Air Canada deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:05 pm
STL
- LIM
2 stops27h 25m
Multiple Airlines
Sun 11/228:00 am
LIM
- STL
1 stop32h 26m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$683
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:00 am
STL
- CTG
1 stop9h 15m
American Airlines
Tue 8/183:15 pm
CTG
- STL
2 stops17h 09m
American Airlines
Deal found 7/20![American Airlines logo]()
$585
This oojo deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:00 am
STL
- LIM
2 stops15h 10m
LATAM Airlines
Wed 1/2011:40 pm
LIM
- STL
1 stop19h 21m
LATAM Airlines
Deal found 7/21![LATAM Airlines logo]()
$731
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am
STL
- CTG
1 stop7h 15m
Delta
Sun 9/204:30 am
CTG
- STL
2 stops19h 12m
Delta
Deal found 7/21![Delta logo]()
$702
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:13 pm
STL
- CTG
2 stops19h 22m
American Airlines
Mon 9/281:35 pm
CTG
- STL
2 stops20h 54m
American Airlines
Deal found 7/20![American Airlines logo]()
$592
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:00 am
STL
- CTG
2 stops16h 00m
United Airlines
Mon 8/319:45 am
CTG
- STL
2 stops24h 25m
United Airlines
Deal found 7/23![United Airlines logo]()
$720
This LATAM Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:00 am
STL
- LIM
2 stops12h 25m
Multiple Airlines
Wed 1/2012:00 pm
LIM
- STL
1 stop12h 39m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$765
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/1311:51 am
STL
- LIM
1 stop16h 09m
Delta
Wed 4/712:05 am
LIM
- STL
1 stop17h 01m
Delta
Deal found 7/20![Delta logo]()
$765
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:30 pm
STL
- BOG
2 stops11h 24m
United Airlines
Sun 9/612:14 am
BOG
- STL
2 stops22h 47m
United Airlines
Deal found 7/22![United Airlines logo]()
$798
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:00 am
STL
- MDE
1 stop15h 15m
American Airlines
Sat 9/126:00 am
MDE
- STL
1 stop17h 59m
American Airlines
Deal found 7/22![American Airlines logo]()
$667
This Air Canada deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:55 am
STL
- GRU
1 stop22h 10m
Air Canada
Thu 10/19:00 pm
GRU
- STL
1 stop23h 41m
Air Canada
Deal found 7/19![Air Canada logo]()
$983
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/63:40 pm
STL
- LIM
1 stop12h 20m
Delta
Wed 1/2012:00 pm
LIM
- STL
1 stop12h 39m
Delta
Deal found 7/23![Delta logo]()
$765
This Air Canada deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:10 pm
STL
- GRU
1 stop19h 40m
Air Canada
Sat 10/179:00 pm
GRU
- STL
2 stops19h 00m
Air Canada
Deal found 7/20![Air Canada logo]()
$986
This LATAM Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:00 am
STL
- GIG
2 stops17h 15m
LATAM Airlines
Mon 8/2411:10 am
GIG
- STL
2 stops26h 36m
LATAM Airlines
Deal found 7/20![LATAM Airlines logo]()
$1,004
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:00 am
STL
- BOG
2 stops16h 00m
United Airlines
Tue 8/47:20 am
BOG
- STL
2 stops16h 09m
United Airlines
Deal found 7/20![United Airlines logo]()
$830
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:00 am
STL
- CTG
1 stop7h 35m
American Airlines
Mon 9/141:35 pm
CTG
- STL
2 stops20h 54m
American Airlines
Deal found 7/24![American Airlines logo]()
$692
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/146:00 am
STL
- LIM
2 stops13h 30m
Delta
Wed 4/1412:10 am
LIM
- STL
2 stops17h 51m
Delta
Deal found 7/20![Delta logo]()
$765
This Air Canada deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:55 am
STL
- GRU
2 stops22h 55m
Air Canada
Wed 9/309:00 pm
GRU
- STL
1 stop23h 41m
Air Canada
Deal found 7/20![Air Canada logo]()
$987
This LATAM Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:00 pm
STL
- SCL
2 stops16h 55m
LATAM Airlines
Sun 11/15:00 pm
SCL
- STL
2 stops33h 48m
LATAM Airlines
Deal found 7/21![LATAM Airlines logo]()
$1,007
Last-minute flights from St. Louis to South AmericaDiscover last-minute flight deals from St. Louis to South America. Data last updated July 24, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to South America. Data last updated July 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:48 pm
STL
- CTG
2 stops18h 47m
American Airlines
Tue 7/281:35 pm
CTG
- STL
2 stops19h 11m
American Airlines
Deal found 7/19![American Airlines logo]()
$683
This FlightHub deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:58 pm
STL
- BOG
1 stop24h 17m
LATAM Airlines
Tue 8/42:55 pm
BOG
- STL
1 stop8h 26m
LATAM Airlines
Deal found 7/20![LATAM Airlines logo]()
$646
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:38 am
STL
- BOG
1 stop13h 52m
American Airlines
Tue 8/46:30 am
BOG
- STL
2 stops14h 51m
American Airlines
Deal found 7/20![American Airlines logo]()
$700
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:00 am
STL
- CTG
1 stop9h 15m
American Airlines
Tue 8/183:15 pm
CTG
- STL
2 stops17h 09m
American Airlines
Deal found 7/20![American Airlines logo]()
$585
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:00 am
STL
- CTG
1 stop9h 15m
American Airlines
Mon 8/173:15 pm
CTG
- STL
1 stop19h 24m
American Airlines
Deal found 7/20![American Airlines logo]()
$676
This LATAM Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 am
STL
- BOG
2 stops14h 10m
LATAM Airlines
Mon 8/242:55 pm
BOG
- STL
1 stop9h 03m
LATAM Airlines
Deal found 7/20![LATAM Airlines logo]()
$486
This CheapOair deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:55 am
STL
- BOG
2 stops17h 05m
Multiple Airlines
Mon 8/247:30 am
BOG
- STL
3 stops26h 09m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$699
This Expedia deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/182:40 pm
STL
- MDE
2 stops22h 30m
Multiple Airlines
Thu 8/208:50 pm
MDE
- STL
2 stops23h 34m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$727
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:00 am
STL
- BOG
1 stop8h 05m
American Airlines
Sat 8/296:30 am
BOG
- STL
1 stop16h 10m
American Airlines
Deal found 7/22![American Airlines logo]()
$481
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:20 am
STL
- BOG
2 stops13h 50m
Delta
Sat 8/2911:00 am
BOG
- STL
2 stops22h 37m
Delta
Deal found 7/22![Delta logo]()
$516
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:35 am
STL
- MDE
1 stop8h 40m
American Airlines
Tue 9/16:00 am
MDE
- STL
1 stop16h 40m
American Airlines
Deal found 7/22![American Airlines logo]()
$679
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:15 am
STL
- MDE
1 stop9h 55m
United Airlines
Tue 9/19:45 am
MDE
- STL
1 stop24h 25m
United Airlines
Deal found 7/23![United Airlines logo]()
$742
One-way flights from St. Louis to South AmericaSearch for one-way flight options from St. Louis to South America. Find affordable one-way fares based on user searches. Data last updated July 24, 2026.
Search for one-way flight options from St. Louis to South America. Find affordable one-way fares based on user searches. Data last updated July 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:17 pm
STL
- BOG
2 stops25h 53m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:17 pm
STL
- LIM
3 stops58h 44m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:17 pm
STL
- LIM
3 stops34h 44m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1210:35 am
STL
- CTG
3 stops27h 30m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:57 pm
STL
- MDE
2 stops39h 18m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$279
This eDestinos deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:34 pm
STL
- BOG
3 stops29h 48m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$280
This Justfly.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:55 am
STL
- BOG
1 stop29h 10m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:17 pm
STL
- LIM
3 stops53h 53m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:27 pm
STL
- LIM
3 stops35h 34m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$292
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/123:34 pm
STL
- CTG
2 stops21h 01m
American Airlines
Deal found 7/21![American Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:17 pm
STL
- LIM
3 stops58h 44m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/74:57 pm
STL
- MDE
2 stops39h 18m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$301
Find flight deals from St. Louis to South America
Keep the following information in mind while searching for St. Louis to South America flight deals. Data was last updated July 24, 2026.
Round-trip from | $481 (American Airlines) |
|---|---|
One-way from | $226 (Kiwi.com) |
Popular in | April |
Cheapest in | June |
Average price | $705 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
Use the filters below to find and compare flights from St. Louis to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
St. LouisBogotá
STL - BOG
STLBOG
Lambert-St Louis
Fri 8/21
5:00 am-1:05 pm
1 stop8h 05m
Bogotá El Dorado
Sat 8/29
6:30 am-10:40 pm
1 stop16h 10m
$481
St. LouisBogotá
STL - BOG
STLBOG
Lambert-St Louis
Fri 9/18
6:53 am-9:17 pm
2 stops14h 24m
Bogotá El Dorado
Tue 9/22
6:30 am-7:07 pm
2 stops12h 37m
$494
St. LouisBogotá
STL - BOG
STLBOG
Lambert-St Louis
Mon 9/7
7:00 am-8:10 pm
2 stops13h 10m
Bogotá El Dorado
Mon 9/14
11:00 am-11:42 pm
2 stops12h 42m
$506
St. LouisBogotá
STL - BOG
STLBOG
Lambert-St Louis
Fri 8/21
6:20 am-8:10 pm
2 stops13h 50m
Bogotá El Dorado
Sat 8/29
11:00 am-9:37 am
2 stops22h 37m
$516
St. LouisBogotá
STL - BOG
STLBOG
Lambert-St Louis
Thu 9/3
6:36 am-10:34 pm
1 stop15h 58m
Bogotá El Dorado
Sat 9/5
12:25 am-7:51 pm
1 stop19h 26m
$538
St. LouisCartagena
STL - CTG
STLCTG
Lambert-St Louis
Fri 8/14
5:00 am-2:15 pm
1 stop9h 15m
Cartagena Rafael Nunez
Tue 8/18
3:15 pm-8:24 am
2 stops17h 09m
$585
St. LouisCartagena
STL - CTG
STLCTG
Lambert-St Louis
Fri 9/25
5:13 pm-12:35 pm
2 stops19h 22m
Cartagena Rafael Nunez
Mon 9/28
1:35 pm-10:29 am
2 stops20h 54m
$592
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Wed 9/16
8:35 am-9:10 pm
1 stop12h 35m
Medellín Jose Maria Cordova Intl
Mon 9/28
9:45 am-10:30 pm
1 stop12h 45m
$630
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Fri 10/16
6:15 am-9:10 pm
1 stop14h 55m
Medellín Jose Maria Cordova Intl
Wed 10/28
9:45 am-10:20 pm
1 stop12h 35m
$645
St. LouisBogotá
STL - BOG
STLBOG
Lambert-St Louis
Thu 7/30
6:58 pm-7:15 pm
1 stop24h 17m
Bogotá El Dorado
Tue 8/4
2:55 pm-11:21 pm
1 stop8h 26m
$646
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from St. Louis to South America
Have a flexible travel schedule? Discover the best time to fly to South America from St. Louis with our price prediction graph.
STL-BOG
STL-LIM
STL-CTG
STL-MDE
STL-GIG
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to South America
STL-0SA
STL-BOG
STL-LIM
STL-CTG
STL-MDE
What is the cheapest month to book a flight from St. Louis to South America?
Currently, October is the cheapest month in which you can book a flight from St. Louis to South America (average of $817). Flying from St. Louis to South America in December is currently the most expensive (average of $1,185). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from St. Louis to South America?
To ensure you get the cheapest price possible for a flight from St. Louis to South America, you should look to book at least 47 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 24, 2026.
Peruse reviews from past customers who have flown with Delta,LATAM Airlines, andUnited Airlines from St. Louis to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from St. Louis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for St. Louis to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to South America by cabin class
Find flights from St. Louis to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and South America flights
Browse other St. Louis and South America flight options. Last updated on July 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
St. Louis to South America flights
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Top 4 airlines flying from St. Louis to South America
Discover the top 4 airlines that operate flights from St. Louis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$536 | Average$919 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$554 | Average$1,011 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$582 | Average$936 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$615 | Average$905 | FlexibilityNo cancel fee | On-time69% |