$230+ Cheap flights from St. Louis (STL) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BOG
Jul 12 — Jul 191
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from St. Louis to South AmericaExplore the most affordable flight options available from St. Louis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
Explore the most affordable flight options available from St. Louis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:42 pm
STL
- CTG
1 stop21h 33m
Delta
Tue 3/23:25 pm
CTG
- STL
1 stop9h 14m
Delta
Deal found 6/8![Delta logo]()
$537
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:07 pm
STL
- CTG
2 stops18h 08m
American Airlines
Tue 8/251:35 pm
CTG
- STL
2 stops19h 49m
American Airlines
Deal found 6/10![American Airlines logo]()
$572
This Justfly.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:55 am
STL
- BOG
1 stop21h 00m
Multiple Airlines
Mon 9/284:15 pm
BOG
- STL
1 stop27h 45m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$572
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:13 pm
STL
- CTG
2 stops20h 04m
American Airlines
Sat 7/183:17 pm
CTG
- STL
2 stops19h 18m
American Airlines
Deal found 6/8![American Airlines logo]()
$593
This FlightHub deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:15 pm
STL
- BOG
1 stop12h 55m
Multiple Airlines
Thu 11/2612:10 am
BOG
- STL
1 stop16h 20m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$593
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:00 am
STL
- CTG
1 stop7h 35m
American Airlines
Wed 9/91:35 pm
CTG
- STL
1 stop8h 14m
American Airlines
Deal found 6/11![American Airlines logo]()
$597
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:00 am
STL
- CTG
2 stops9h 14m
American Airlines
Tue 3/28:00 am
CTG
- STL
2 stops13h 18m
American Airlines
Deal found 6/11![American Airlines logo]()
$602
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am
STL
- CTG
1 stop7h 15m
Delta
Wed 11/113:25 pm
CTG
- STL
1 stop9h 14m
Delta
Deal found 6/7![Delta logo]()
$608
This Air Canada deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:15 pm
STL
- LIM
2 stops17h 30m
Air Canada
Sun 11/228:00 am
LIM
- STL
1 stop32h 30m
Air Canada
Deal found 6/9![Air Canada logo]()
$609
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:00 am
STL
- CTG
1 stop7h 15m
Delta
Wed 9/94:25 am
CTG
- STL
2 stops19h 12m
Delta
Deal found 6/8![Delta logo]()
$611
This Air Canada deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:15 pm
STL
- LIM
2 stops23h 15m
Multiple Airlines
Sun 11/225:35 pm
LIM
- STL
2 stops46h 55m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$637
This Avianca deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:15 pm
STL
- BOG
1 stop12h 55m
Multiple Airlines
Thu 11/264:00 am
BOG
- STL
2 stops13h 35m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$638
Best flights from St. Louis to South AmericaDiscover carefully curated flight deals from St. Louis to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
Discover carefully curated flight deals from St. Louis to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:00 am
STL
- CTG
1 stop7h 15m
Delta
Wed 9/94:25 am
CTG
- STL
2 stops19h 12m
Delta
Deal found 6/11![Delta logo]()
$572
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:07 pm
STL
- CTG
2 stops18h 08m
American Airlines
Tue 8/251:35 pm
CTG
- STL
2 stops19h 49m
American Airlines
Deal found 6/10![American Airlines logo]()
$572
This Orbitz deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:55 am
STL
- BOG
2 stops17h 05m
Multiple Airlines
Mon 9/712:05 am
BOG
- STL
1 stop13h 55m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$650
This LATAM Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 am
STL
- BOG
2 stops14h 35m
LATAM Airlines
Tue 9/810:35 am
BOG
- STL
2 stops13h 02m
LATAM Airlines
Deal found 6/9![LATAM Airlines logo]()
$655
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:30 pm
STL
- MDE
2 stops27h 40m
United Airlines
Wed 8/269:45 am
MDE
- STL
2 stops26h 17m
United Airlines
Deal found 6/6![United Airlines logo]()
$669
This GOL deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:21 pm
STL
- GIG
1 stop14h 04m
GOL
Wed 1/1310:30 pm
GIG
- STL
1 stop15h 35m
GOL
Deal found 6/8![GOL logo]()
$944
This Air Canada deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/274:15 pm
STL
- GRU
2 stops37h 45m
Air Canada
Tue 12/19:30 pm
GRU
- STL
1 stop21h 00m
Air Canada
Deal found 6/9![Air Canada logo]()
$967
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:13 pm
STL
- CTG
2 stops20h 04m
American Airlines
Sat 7/183:17 pm
CTG
- STL
2 stops19h 18m
American Airlines
Deal found 6/8![American Airlines logo]()
$593
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:07 pm
STL
- CTG
2 stops18h 08m
American Airlines
Wed 9/91:35 pm
CTG
- STL
2 stops20h 45m
American Airlines
Deal found 6/11![American Airlines logo]()
$602
This LATAM Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:58 pm
STL
- CTG
1 stop18h 11m
LATAM Airlines
Sat 7/182:30 pm
CTG
- STL
1 stop17h 49m
LATAM Airlines
Deal found 6/10![LATAM Airlines logo]()
$684
This Aviatur deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aviatur is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
STL
- BOG
1 stop7h 40m
LATAM Airlines
Wed 8/52:55 pm
BOG
- STL
1 stop18h 59m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$693
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am
STL
- LIM
2 stops15h 40m
Delta
Mon 10/1212:15 am
LIM
- STL
2 stops14h 25m
Delta
Deal found 6/11![Delta logo]()
$770
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:01 am
STL
- BOG
1 stop15h 59m
United Airlines
Wed 7/157:20 am
BOG
- STL
1 stop16h 24m
United Airlines
Deal found 6/10![United Airlines logo]()
$779
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:48 pm
STL
- CTG
2 stops18h 47m
American Airlines
Tue 7/283:17 pm
CTG
- STL
2 stops18h 44m
American Airlines
Deal found 6/7![American Airlines logo]()
$652
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:00 am
STL
- LIM
2 stops14h 35m
Delta
Sun 11/2212:00 pm
LIM
- STL
1 stop21h 12m
Delta
Deal found 6/7![Delta logo]()
$790
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:00 am
STL
- BOG
2 stops22h 54m
United Airlines
Sat 7/1812:14 am
BOG
- STL
1 stop9h 53m
United Airlines
Deal found 6/9![United Airlines logo]()
$810
This LATAM Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:00 am
STL
- LIM
2 stops14h 20m
LATAM Airlines
Wed 9/212:05 pm
LIM
- STL
1 stop11h 16m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$765
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:45 pm
STL
- CTG
2 stops17h 50m
American Airlines
Sun 8/93:15 pm
CTG
- STL
1 stop19h 24m
American Airlines
Deal found 6/7![American Airlines logo]()
$709
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:00 am
STL
- BOG
1 stop7h 40m
Delta
Sun 7/192:55 pm
BOG
- STL
1 stop17h 24m
Delta
Deal found 6/9![Delta logo]()
$795
This GOL deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:35 am
STL
- GIG
1 stop18h 45m
GOL
Thu 9/32:55 pm
GIG
- STL
2 stops21h 50m
GOL
Deal found 6/7![GOL logo]()
$981
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:10 pm
STL
- VCP
1 stop35h 50m
Multiple Airlines
Mon 9/710:40 pm
VCP
- STL
2 stops37h 00m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$986
This Air Canada deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:55 am
STL
- GRU
2 stops22h 55m
Air Canada
Wed 9/309:35 pm
GRU
- STL
1 stop18h 25m
Air Canada
Deal found 6/7![Air Canada logo]()
$1,016
This LATAM Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:00 am
STL
- BOG
2 stops11h 05m
LATAM Airlines
Wed 7/152:55 pm
BOG
- STL
1 stop8h 58m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$768
This GOL deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:34 pm
STL
- GIG
2 stops20h 36m
GOL
Thu 10/12:55 pm
GIG
- STL
2 stops22h 57m
GOL
Deal found 6/8![GOL logo]()
$993
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/179:00 am
STL
- LIM
1 stop20h 00m
Delta
Fri 11/2012:05 am
LIM
- STL
2 stops18h 56m
Delta
Deal found 6/11![Delta logo]()
$829
This FlightHub deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:55 am
STL
- GRU
2 stops22h 55m
Air Canada
Wed 9/169:35 pm
GRU
- STL
1 stop18h 25m
Air Canada
Deal found 6/11![Air Canada logo]()
$1,022
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:17 pm
STL
- SCL
1 stop13h 33m
United Airlines
Tue 11/1010:45 pm
SCL
- STL
1 stop22h 53m
United Airlines
Deal found 6/8![United Airlines logo]()
$948
This LATAM Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
STL
- LIM
1 stop15h 55m
LATAM Airlines
Tue 9/88:55 am
LIM
- STL
2 stops14h 42m
LATAM Airlines
Deal found 6/9![LATAM Airlines logo]()
$790
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:00 am
STL
- LIM
2 stops13h 30m
American Airlines
Mon 10/511:59 pm
LIM
- STL
1 stop17h 24m
American Airlines
Deal found 6/8![American Airlines logo]()
$795
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:30 am
STL
- GRU
2 stops24h 50m
Multiple Airlines
Wed 7/1511:40 am
GRU
- STL
1 stop14h 19m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$1,113
Last-minute flights from St. Louis to South AmericaDiscover last-minute flight deals from St. Louis to South America. Data last updated June 12, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to South America. Data last updated June 12, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:12 pm
STL
- BOG
1 stop18h 28m
Delta
Fri 6/195:00 am
BOG
- STL
2 stops18h 56m
Delta
Deal found 6/11![Delta logo]()
$695
This KAYAK deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/148:35 am
STL
- CTG
2 stops14h 25m
Copa Airlines
Tue 6/166:20 am
CTG
- STL
2 stops16h 25m
Copa Airlines
Deal found 6/10![Copa Airlines logo]()
$765
This Expedia deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:12 pm
STL
- BOG
2 stops25h 23m
LATAM Airlines
Tue 6/232:55 pm
BOG
- STL
1 stop9h 01m
LATAM Airlines
Deal found 6/11![LATAM Airlines logo]()
$731
This Expedia deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/202:15 pm
STL
- MDE
2 stops22h 55m
Multiple Airlines
Wed 6/242:10 pm
MDE
- STL
2 stops22h 11m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$742
This Ovago deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:14 am
STL
- MDE
1 stop14h 56m
Multiple Airlines
Mon 7/69:45 am
MDE
- STL
1 stop13h 00m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$775
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:14 am
STL
- MDE
1 stop14h 56m
United Airlines
Tue 7/149:45 am
MDE
- STL
1 stop13h 00m
United Airlines
Deal found 6/9![United Airlines logo]()
$679
This LATAM Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:00 am
STL
- BOG
2 stops11h 05m
LATAM Airlines
Wed 7/152:55 pm
BOG
- STL
1 stop8h 58m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$768
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:13 pm
STL
- CTG
2 stops20h 04m
American Airlines
Sat 7/183:17 pm
CTG
- STL
2 stops19h 18m
American Airlines
Deal found 6/8![American Airlines logo]()
$593
This LATAM Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:58 pm
STL
- CTG
1 stop18h 11m
LATAM Airlines
Sat 7/182:30 pm
CTG
- STL
1 stop17h 49m
LATAM Airlines
Deal found 6/10![LATAM Airlines logo]()
$684
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:18 am
STL
- MDE
1 stop14h 58m
American Airlines
Thu 7/1612:30 am
MDE
- STL
1 stop9h 54m
American Airlines
Deal found 6/10![American Airlines logo]()
$703
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:48 pm
STL
- CTG
2 stops18h 47m
American Airlines
Tue 7/281:35 pm
CTG
- STL
2 stops19h 17m
American Airlines
Deal found 6/11![American Airlines logo]()
$652
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:14 am
STL
- MDE
1 stop14h 56m
United Airlines
Sun 8/29:45 am
MDE
- STL
2 stops30h 01m
United Airlines
Deal found 6/7![United Airlines logo]()
$770
One-way flights from St. Louis to South AmericaSearch for one-way flight options from St. Louis to South America. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
Search for one-way flight options from St. Louis to South America. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/254:57 pm
STL
- BOG
3 stops48h 23m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:33 pm
STL
- BOG
3 stops41h 07m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:33 pm
STL
- MDE
2 stops29h 17m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$268
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:56 pm
STL
- CTG
2 stops18h 21m
American Airlines
Deal found 6/9![American Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:33 pm
STL
- SCL
3 stops30h 47m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:33 pm
STL
- MDE
3 stops29h 17m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/114:57 pm
STL
- BOG
3 stops31h 09m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:57 pm
STL
- SCL
3 stops49h 39m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:18 am
STL
- CTG
1 stop8h 59m
American Airlines
Deal found 6/8![American Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:32 am
STL
- BOG
2 stops13h 45m
American Airlines
Deal found 6/10![American Airlines logo]()
$373
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:06 pm
STL
- LIM
3 stops35h 55m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:34 pm
STL
- CTG
3 stops28h 26m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$375
Find flight deals from St. Louis to South America
Keep the following information in mind while searching for St. Louis to South America flight deals. Data was last updated June 12, 2026.
Round-trip from | $572 (American Airlines) |
|---|---|
One-way from | $230 (Kiwi.com) |
Popular in | June |
Cheapest in | January |
Average price | $1,200 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from St. Louis to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCartagena
STL - CTG
STLCTG
Lambert-St Louis
Thu 8/27
6:00 am-1:15 pm
1 stop7h 15m
Cartagena Rafael Nunez
Wed 9/9
4:25 am-11:37 pm
2 stops19h 12m
$572
St. LouisCartagena
STL - CTG
STLCTG
Lambert-St Louis
Fri 8/21
8:07 pm-2:15 pm
2 stops18h 08m
Cartagena Rafael Nunez
Tue 8/25
1:35 pm-9:24 am
2 stops19h 49m
$572
St. LouisCartagena
STL - CTG
STLCTG
Lambert-St Louis
Fri 7/10
6:13 pm-2:17 pm
2 stops20h 04m
Cartagena Rafael Nunez
Sat 7/18
3:17 pm-10:35 am
2 stops19h 18m
$593
St. LouisCartagena
STL - CTG
STLCTG
Lambert-St Louis
Thu 8/27
8:07 pm-2:15 pm
2 stops18h 08m
Cartagena Rafael Nunez
Wed 9/9
1:35 pm-10:20 am
2 stops20h 45m
$602
St. LouisBogotá
STL - BOG
STLBOG
Lambert-St Louis
Wed 9/2
8:55 am-2:00 am
2 stops17h 05m
Bogotá El Dorado
Mon 9/7
12:05 am-2:00 pm
1 stop13h 55m
$650
St. LouisCartagena
STL - CTG
STLCTG
Lambert-St Louis
Thu 7/23
5:48 pm-12:35 pm
2 stops18h 47m
Cartagena Rafael Nunez
Tue 7/28
3:17 pm-10:01 am
2 stops18h 44m
$652
St. LouisBogotá
STL - BOG
STLBOG
Lambert-St Louis
Wed 9/2
6:00 am-8:35 pm
2 stops14h 35m
Bogotá El Dorado
Tue 9/8
10:35 am-11:37 pm
2 stops13h 02m
$655
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Sat 8/22
5:30 pm-9:10 pm
2 stops27h 40m
Medellín Jose Maria Cordova Intl
Wed 8/26
9:45 am-12:02 pm
2 stops26h 17m
$669
St. LouisCartagena
STL - CTG
STLCTG
Lambert-St Louis
Fri 7/10
6:58 pm-1:09 pm
1 stop18h 11m
Cartagena Rafael Nunez
Sat 7/18
2:30 pm-8:19 am
1 stop17h 49m
$684
St. LouisBogotá
STL - BOG
STLBOG
Lambert-St Louis
Tue 8/4
6:00 am-1:40 pm
1 stop7h 40m
Bogotá El Dorado
Wed 8/5
2:55 pm-9:54 am
1 stop18h 59m
$693
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from St. Louis to South America
Have a flexible travel schedule? Discover the best time to fly to South America from St. Louis with our price prediction graph.
STL-BOG
STL-MDE
STL-CTG
STL-SCL
STL-LIM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to South America
STL-0SA
STL-BOG
STL-MDE
STL-CTG
STL-SCL
What is the cheapest month to book a flight from St. Louis to South America?
Currently, July is the cheapest month in which you can book a flight from St. Louis to South America (average of $178). Flying from St. Louis to South America in June is currently the most expensive (average of $543). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from St. Louis to South America?
To ensure you get the cheapest price possible for a flight from St. Louis to South America, you should look to book at least 48 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated June 12, 2026.
Peruse reviews from past customers who have flown with Delta,LATAM Airlines, andUnited Airlines from St. Louis to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.9
Comfort
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Overall
7.9
Comfort
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Overall
7.9
Comfort
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Overall
7.9
Comfort
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Overall
7.9
Comfort
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Overall
7.9
Comfort
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from St. Louis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for St. Louis to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to South America by cabin class
Find flights from St. Louis to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and South America flights
Browse other St. Louis and South America flight options. Last updated on June 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
St. Louis to South America flights
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Top 4 airlines flying from St. Louis to South America
Discover the top 4 airlines that operate flights from St. Louis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$536 | Average$981 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$563 | Average$1,004 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$574 | Average$926 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$615 | Average$675 | FlexibilityNo cancel fee | On-time69% |