$234+ Cheap flights from St. Louis (STL) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BOG
Sep 30 — Oct 71
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to South America
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Cheapest flights from St. Louis to South AmericaExplore the most affordable flight options available from St. Louis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 31, 2026.
Explore the most affordable flight options available from St. Louis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 31, 2026.
This eDestinos deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop12h 30m
Wed 1/203:55 pm -
1 stop17h 17m
Deal found 8/26![LATAM Airlines logo]()
$538
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:43 am -
1 stop16h 47m
Fri 9/252:10 pm -
1 stop9h 49m
Deal found 8/26![American Airlines logo]()
$541
This LATAM Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:00 am -
2 stops11h 10m
Wed 1/203:55 pm -
1 stop17h 17m
Deal found 8/26![Multiple Airlines logo]()
$543
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:05 am -
2 stops13h 05m
Mon 9/212:55 pm -
1 stop18h 05m
Deal found 8/27![Delta logo]()
$546
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:36 am -
1 stop13h 58m
Thu 9/312:25 am -
1 stop23h 17m
Deal found 8/28![American Airlines logo]()
$549
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:00 am -
1 stop11h 35m
Wed 11/48:15 am -
1 stop9h 35m
Deal found 8/26![United Airlines logo]()
$556
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:15 am -
1 stop15h 20m
Thu 11/261:30 am -
1 stop13h 43m
Deal found 8/28![United Airlines logo]()
$571
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:00 am -
1 stop8h 05m
Sun 9/206:30 am -
1 stop17h 29m
Deal found 8/27![American Airlines logo]()
$578
This LATAM Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:20 pm -
2 stops23h 45m
Tue 10/137:10 am -
2 stops16h 44m
Deal found 8/27![LATAM Airlines logo]()
$623
This CheapOair deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:05 pm -
2 stops17h 45m
Tue 11/39:45 pm -
2 stops18h 41m
Deal found 8/28![Multiple Airlines logo]()
$672
This LATAM Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop12h 59m
Wed 10/149:00 am -
2 stops14h 54m
Deal found 8/28![LATAM Airlines logo]()
$679
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:00 am -
1 stop11h 59m
Tue 10/1312:59 am -
1 stop15h 29m
Deal found 8/28![Delta logo]()
$687
Best flights from St. Louis to South AmericaDiscover carefully curated flight deals from St. Louis to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 31, 2026.
Discover carefully curated flight deals from St. Louis to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 31, 2026.
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:05 am -
1 stop12h 10m
Mon 9/212:55 pm -
1 stop18h 05m
Deal found 8/27![Delta logo]()
$541
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:00 am -
1 stop11h 35m
Wed 11/48:15 am -
1 stop9h 35m
Deal found 8/28![United Airlines logo]()
$556
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:00 am -
2 stops14h 17m
Sun 10/46:30 am -
1 stop17h 29m
Deal found 8/30![American Airlines logo]()
$670
This LATAM Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop12h 59m
Tue 10/139:00 am -
2 stops14h 54m
Deal found 8/30![LATAM Airlines logo]()
$753
This LATAM Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:35 pm -
1 stop14h 40m
Mon 10/197:05 am -
2 stops18h 49m
Deal found 8/27![Multiple Airlines logo]()
$1,053
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:05 am -
1 stop12h 10m
Mon 9/282:55 pm -
1 stop8h 47m
Deal found 8/27![Delta logo]()
$541
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:15 am -
1 stop15h 20m
Thu 11/261:30 am -
1 stop13h 43m
Deal found 8/28![United Airlines logo]()
$571
This FlightHub deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:05 pm -
1 stop15h 30m
Wed 11/119:30 pm -
1 stop20h 56m
Deal found 8/29![Air Canada logo]()
$1,175
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:00 am -
1 stop7h 40m
Tue 10/209:00 am -
1 stop14h 54m
Deal found 8/28![Delta logo]()
$541
This GOL deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:20 pm -
1 stop15h 40m
Thu 10/2912:05 am -
1 stop19h 22m
Deal found 8/26![GOL logo]()
$1,254
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:00 am -
1 stop15h 15m
Wed 11/47:30 am -
1 stop9h 20m
Deal found 8/31![American Airlines logo]()
$687
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:15 am -
1 stop14h 55m
Wed 10/219:45 am -
1 stop12h 45m
Deal found 8/29![United Airlines logo]()
$687
This FlightHub deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:00 am -
2 stops12h 25m
Sun 11/2212:10 pm -
1 stop12h 46m
Deal found 8/26![LATAM Airlines logo]()
$756
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:00 am -
1 stop11h 59m
Tue 10/1312:59 am -
1 stop15h 29m
Deal found 8/28![Delta logo]()
$687
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:15 am -
1 stop14h 55m
Wed 11/410:40 am -
2 stops24h 52m
Deal found 8/31![United Airlines logo]()
$692
This LATAM Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:00 am -
2 stops14h 50m
Tue 1/1212:15 am -
2 stops33h 37m
Deal found 8/30![LATAM Airlines logo]()
$765
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:29 am -
2 stops13h 57m
Sun 11/2210:55 pm -
1 stop12h 12m
Deal found 8/29![American Airlines logo]()
$770
This LATAM Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:25 am -
2 stops20h 40m
Sun 11/158:40 pm -
2 stops20h 43m
Deal found 8/28![LATAM Airlines logo]()
$765
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am -
2 stops14h 32m
Sun 11/1510:55 pm -
1 stop12h 13m
Deal found 8/28![American Airlines logo]()
$770
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:15 am -
1 stop14h 55m
Sat 10/249:45 am -
1 stop10h 31m
Deal found 8/28![United Airlines logo]()
$704
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:14 am -
1 stop8h 45m
Mon 10/1212:59 am -
1 stop9h 52m
Deal found 8/30![Delta logo]()
$763
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:15 am -
1 stop17h 10m
Sat 10/1712:35 am -
1 stop9h 35m
Deal found 8/27![United Airlines logo]()
$727
This LATAM Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am -
2 stops17h 00m
Mon 9/216:35 pm -
2 stops23h 05m
Deal found 8/30![LATAM Airlines logo]()
$813
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/62:15 pm -
1 stop17h 45m
Wed 1/2012:10 pm -
1 stop21h 02m
Deal found 8/30![Delta logo]()
$765
This deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:30 am -
1 stop12h 40m
Sat 11/710:40 am -
1 stop12h 46m
Deal found 8/28![United Airlines logo]()
$729
This KAYAK deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/33:03 pm -
2 stops22h 42m
Sun 2/72:50 pm -
2 stops24h 23m
Deal found 8/28![Multiple Airlines logo]()
$1,262
This LATAM Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:18 pm -
2 stops22h 34m
Fri 11/2712:55 am -
1 stop16h 48m
Deal found 8/29![LATAM Airlines logo]()
$865
This Air Canada deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:10 pm -
1 stop19h 40m
Wed 9/309:00 pm -
1 stop23h 41m
Deal found 8/26![Air Canada logo]()
$1,278
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:01 pm -
2 stops28h 24m
Mon 10/197:00 am -
2 stops29h 13m
Deal found 8/28![United Airlines logo]()
$730
This GOL deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:07 pm -
2 stops34h 48m
Sun 10/1810:05 pm -
2 stops45h 44m
Deal found 8/27![GOL logo]()
$1,296
Last-minute flights from St. Louis to South AmericaDiscover last-minute flight deals from St. Louis to South America. Data last updated August 31, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to South America. Data last updated August 31, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:40 pm -
2 stops22h 30m
Tue 9/12:10 pm -
2 stops19h 29m
Deal found 8/27![Multiple Airlines logo]()
$826
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:36 am -
1 stop13h 58m
Thu 9/312:25 am -
1 stop23h 17m
Deal found 8/28![American Airlines logo]()
$549
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:25 am -
2 stops21h 29m
Fri 9/48:30 am -
2 stops27h 33m
Deal found 8/28![United Airlines logo]()
$576
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/411:35 am -
1 stop9h 42m
Tue 9/86:30 am -
1 stop16h 10m
Deal found 8/30![American Airlines logo]()
$661
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:00 am -
1 stop8h 05m
Sun 9/206:30 am -
1 stop17h 29m
Deal found 8/27![American Airlines logo]()
$578
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:05 am -
2 stops13h 05m
Mon 9/212:55 pm -
1 stop18h 05m
Deal found 8/27![Delta logo]()
$546
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:43 am -
1 stop16h 47m
Fri 9/252:10 pm -
1 stop9h 49m
Deal found 8/26![American Airlines logo]()
$541
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am -
1 stop12h 59m
Sun 9/2012:59 am -
1 stop14h 55m
Deal found 8/27![Delta logo]()
$813
This Justfly.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:54 pm -
1 stop10h 06m
Mon 10/512:05 pm -
1 stop21h 04m
Deal found 8/28![LATAM Airlines logo]()
$815
This Expedia deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:45 pm -
2 stops25h 25m
Sun 9/278:40 am -
2 stops39h 02m
Deal found 8/27![LATAM Airlines logo]()
$609
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:43 am -
2 stops12h 34m
Mon 9/286:30 am -
2 stops16h 12m
Deal found 8/27![American Airlines logo]()
$561
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:43 am -
1 stop16h 47m
Sun 10/46:30 am -
1 stop17h 29m
Deal found 8/30![American Airlines logo]()
$643
One-way flights from St. Louis to South AmericaSearch for one-way flight options from St. Louis to South America. Find affordable one-way fares based on user searches. Data last updated August 31, 2026.
Search for one-way flight options from St. Louis to South America. Find affordable one-way fares based on user searches. Data last updated August 31, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:05 pm -
3 stops52h 10m
Deal found 8/30![Multiple Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:29 pm -
3 stops33h 37m
Deal found 8/27![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:29 pm -
3 stops44h 57m
Deal found 8/29![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:29 pm -
3 stops30h 12m
Deal found 8/26![Multiple Airlines logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:29 pm -
3 stops38h 32m
Deal found 8/26![Multiple Airlines logo]()
$303
This Mytrip deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/304:05 pm -
1 stop21h 05m
Deal found 8/27![Multiple Airlines logo]()
$322
This Expedia deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:55 am -
2 stops25h 40m
Deal found 8/26![Air Canada logo]()
$342
This Air Canada deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:05 pm -
2 stops34h 10m
Deal found 8/30![Air Canada logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/247:31 pm -
2 stops32h 24m
Deal found 8/30![Multiple Airlines logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:26 pm -
3 stops39h 34m
Deal found 8/30![Multiple Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/229:19 am -
3 stops42h 36m
Deal found 8/30![Multiple Airlines logo]()
$404
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/294:26 pm -
3 stops50h 14m
Deal found 8/26![Multiple Airlines logo]()
$420
Find flight deals from St. Louis to South America
Keep the following information in mind while searching for St. Louis to South America flight deals. Data was last updated August 31, 2026.
Round-trip from | $538 (eDestinos) |
|---|---|
One-way from | $234 (Kiwi.com) |
Popular in | April |
Cheapest in | June |
Average price | $817 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 31, 2026.
Use the filters below to find and compare flights from St. Louis to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisBogotá
STL Lambert-St Louis - BOG Bogotá El Dorado
STLBOG
Lambert-St Louis
Wed 9/16
7:05 am-7:15 pm
1 stop12h 10m
Bogotá El Dorado
Mon 9/21
2:55 pm-9:00 am
1 stop18h 05m
$541
St. LouisBogotá
STL Lambert-St Louis - BOG Bogotá El Dorado
STLBOG
Lambert-St Louis
Wed 9/23
7:05 am-7:15 pm
1 stop12h 10m
Bogotá El Dorado
Mon 9/28
2:55 pm-11:42 pm
1 stop8h 47m
$541
St. LouisBogotá
STL Lambert-St Louis - BOG Bogotá El Dorado
STLBOG
Lambert-St Louis
Mon 9/28
6:00 am-1:40 pm
1 stop7h 40m
Bogotá El Dorado
Tue 10/20
9:00 am-11:54 pm
1 stop14h 54m
$541
St. LouisBogotá
STL Lambert-St Louis - BOG Bogotá El Dorado
STLBOG
Lambert-St Louis
Sat 10/31
11:00 am-10:35 pm
1 stop11h 35m
Bogotá El Dorado
Wed 11/4
8:15 am-4:50 pm
1 stop9h 35m
$556
St. LouisBogotá
STL Lambert-St Louis - BOG Bogotá El Dorado
STLBOG
Lambert-St Louis
Fri 11/13
6:15 am-10:35 pm
1 stop15h 20m
Bogotá El Dorado
Thu 11/26
1:30 am-2:13 pm
1 stop13h 43m
$571
St. LouisBogotá
STL Lambert-St Louis - BOG Bogotá El Dorado
STLBOG
Lambert-St Louis
Sun 9/27
7:00 am-9:17 pm
2 stops14h 17m
Bogotá El Dorado
Sun 10/4
6:30 am-11:59 pm
1 stop17h 29m
$670
St. LouisMedellín
STL Lambert-St Louis - MDE Medellín Jose Maria Cordova Intl
STLMDE
Lambert-St Louis
Wed 10/21
5:00 am-8:15 pm
1 stop15h 15m
Medellín Jose Maria Cordova Intl
Wed 11/4
7:30 am-3:50 pm
1 stop9h 20m
$687
St. LouisMedellín
STL Lambert-St Louis - MDE Medellín Jose Maria Cordova Intl
STLMDE
Lambert-St Louis
Wed 10/14
6:15 am-9:10 pm
1 stop14h 55m
Medellín Jose Maria Cordova Intl
Wed 10/21
9:45 am-10:30 pm
1 stop12h 45m
$687
St. LouisQuito
STL Lambert-St Louis - UIO Quito Mariscal Sucr
STLUIO
Lambert-St Louis
Wed 10/7
7:00 am-6:59 pm
1 stop11h 59m
Quito Mariscal Sucr
Tue 10/13
12:59 am-4:28 pm
1 stop15h 29m
$687
St. LouisMedellín
STL Lambert-St Louis - MDE Medellín Jose Maria Cordova Intl
STLMDE
Lambert-St Louis
Wed 10/21
6:15 am-9:10 pm
1 stop14h 55m
Medellín Jose Maria Cordova Intl
Wed 11/4
10:40 am-10:32 am
2 stops24h 52m
$692
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from St. Louis to South America
Have a flexible travel schedule? Discover the best time to fly to South America from St. Louis with our price prediction graph.
STL-BOG
STL-UIO
STL-GIG
STL-GRU
STL-MDE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to South America
STL-0SA
STL-BOG
STL-UIO
STL-GIG
STL-GRU
What is the cheapest month to book a flight from St. Louis to South America?
Currently, September is the cheapest month in which you can book a flight from St. Louis to South America (average of $834). Flying from St. Louis to South America in December is currently the most expensive (average of $1,286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated August 31, 2026.
Peruse reviews from past customers who have flown with Delta,LATAM Airlines, andUnited Airlines from St. Louis to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from St. Louis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for St. Louis to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to South America by cabin class
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St. Louis and South America flights
Browse other St. Louis and South America flight options. Last updated on August 31, 2026.
Popular flight searches
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Fly to South America countries
Consider these flights traveling to countries located in South America.
St. Louis to South America flights
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Top 4 airlines flying from St. Louis to South America
Discover the top 4 airlines that operate flights from St. Louis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 31, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$536 | Average$936 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$563 | Average$1,057 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$582 | Average$996 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$615 | Average$1,009 | FlexibilityNo cancel fee | On-time69% |