What are the cheapest airlines flying from St. Louis to Guayaquil round-trip?

Delta, at $630, was found to be the cheapest airline from St. Louis to Guayaquil.Alternate airlines to your destination round-trip include United Airlines and LATAM Airlines.

What is the cheapest month to book a flight from St. Louis to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from St. Louis to Guayaquil (average of $440). Flying from St. Louis to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest day to fly from St. Louis to Guayaquil?

Travelers seeking maximum savings on their St. Louis to Guayaquil flight should consider departing on Wednesday mornings when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Guayaquil ranges from 0.0 - 11.0 inches per month. March is typically the wettest month, when rainfall can reach 11.0 in. July is typically the driest time to visit Guayaquil when rainfall is around 0.0 in.

If weather is an important factor for your trip to Guayaquil, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 77.0 F).

What is the cheapest day to fly round-trip from St. Louis to Guayaquil?

Flights from St. Louis to Guayaquil are found to be more expensive on Wednesday. This shouldn't discourage you from searching as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Guayaquil.

What is the cheapest time of day to fly from STL to GYE?

Unlike in the morning, when flights are generally more expensive, you can save up to 7% on flights from St. Louis to Guayaquil by exploring options for tickets at noon.

Can I find deals for flights from St. Louis to Guayaquil that include hotel bookings?

Yes. In addition to deals on St. Louis to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from St. Louis to Guayaquil?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Guayaquil.

Can I find deals for business class flights from St. Louis to Guayaquil?

Yes. Cheapflights offers flight deals from St. Louis to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$625+ Flights from St. Louis to Guayaquil

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from St. Louis to Guayaquil with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from St. Louis to Guayaquil

Round-trip from	$625 (United Airlines)

From Lambert-St Louis to Guayaquil Jose Joaquin de Olmedo

Search Deals

Find flight deals from St. Louis to Guayaquil

Cheapest flights from St. Louis to Guayaquil
Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Sat 8/1611:15 amSTL - GYE

2 stops12h 22mMultiple Airlines

Sat 8/234:15 amGYE - STL

2 stops14h 43mMultiple Airlines

Deal found 7/1

$625

Sun 10/56:42 pmSTL - GYE

2 stops27h 41mDelta

Thu 10/98:30 pmGYE - STL

2 stops21h 32mDelta

Deal found 6/30

$630

Thu 12/44:17 pmSTL - GYE

2 stops33h 28mUnited Airlines

Thu 2/193:55 amGYE - STL

2 stops37h 40mUnited Airlines

Deal found 7/2

$655

Sun 10/56:04 amSTL - GYE

2 stops24h 51mLATAM Airlines

Thu 10/98:30 pmGYE - STL

2 stops21h 32mLATAM Airlines

Deal found 7/1

$802

Thu 12/45:25 amSTL - GYE

1 stop15h 40mAmerican Airlines

Fri 2/207:35 amGYE - STL

1 stop9h 03mAmerican Airlines

Deal found 7/1

$842

Best flights from St. Louis to Guayaquil
Discover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2025.

Sat 8/1611:15 amSTL - GYE

2 stops12h 22mMultiple Airlines

Sat 8/234:15 amGYE - STL

2 stops14h 43mMultiple Airlines

Deal found 7/1

$625

Sun 10/56:42 pmSTL - GYE

2 stops27h 41mDelta

Thu 10/98:30 pmGYE - STL

2 stops21h 32mDelta

Deal found 6/30

$630

Thu 12/44:17 pmSTL - GYE

2 stops33h 28mUnited Airlines

Thu 2/193:55 amGYE - STL

2 stops37h 40mUnited Airlines

Deal found 7/2

$655

Sun 10/56:04 amSTL - GYE

2 stops24h 51mLATAM Airlines

Thu 10/98:30 pmGYE - STL

2 stops21h 32mLATAM Airlines

Deal found 7/1

$802

Thu 12/45:25 amSTL - GYE

1 stop15h 40mAmerican Airlines

Fri 2/207:35 amGYE - STL

1 stop9h 03mAmerican Airlines

Deal found 7/3

$842

Last-minute flights from St. Louis to Guayaquil
Discover last-minute flight deals from St. Louis to Guayaquil. Data last updated July 3, 2025 and is based on user searches.

Sat 8/1611:15 amSTL - GYE

2 stops12h 22mMultiple Airlines

Sat 8/234:15 amGYE - STL

2 stops14h 43mMultiple Airlines

Deal found 7/1

$625

Sat 8/165:26 amSTL - GYE

1 stop14h 11mAmerican Airlines

Sat 8/238:10 amGYE - STL

1 stop15h 49mAmerican Airlines

Deal found 7/1

$1,091

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sat 8/16

11:15 am-11:37 pm

2 stops12h 22m

Guayaquil Jose Joaquin de Olmedo

Sat 8/23

4:15 am-6:58 pm

2 stops14h 43m

$625

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sun 10/5

6:42 pm-10:23 pm

2 stops27h 41m

Guayaquil Jose Joaquin de Olmedo

Thu 10/9

8:30 pm-6:02 pm

2 stops21h 32m

$630

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 12/4

4:17 pm-2:45 am

2 stops33h 28m

Guayaquil Jose Joaquin de Olmedo

Thu 2/19

3:55 am-4:35 pm

2 stops37h 40m

$655

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sun 10/5

6:04 am-6:55 am

2 stops24h 51m

Guayaquil Jose Joaquin de Olmedo

Thu 10/9

8:30 pm-6:02 pm

2 stops21h 32m

$802

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 12/4

5:25 am-10:05 pm

1 stop15h 40m

Guayaquil Jose Joaquin de Olmedo

Fri 2/20

7:35 am-3:38 pm

1 stop9h 03m

$842

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from St. Louis to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Guayaquil

See what other customers who have flown with Delta, LATAM Airlines, and United Airlines from St. Louis to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,982 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

LATAM Airlines

7.5

Good

1,805 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,861 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from St. Louis to Guayaquil round-trip?
Delta, at $630, was found to be the cheapest airline from St. Louis to Guayaquil.Alternate airlines to your destination round-trip include United Airlines and LATAM Airlines.
Can I find deals for flights from St. Louis to Guayaquil that include hotel bookings?
Yes. In addition to deals on St. Louis to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Guayaquil?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Guayaquil.
Can I find deals for business class flights from St. Louis to Guayaquil?
Yes. Cheapflights offers flight deals from St. Louis to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Guayaquil?
Currently, April is the cheapest month in which you can book a flight from St. Louis to Guayaquil (average of $440). Flying from St. Louis to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for St. Louis to Guayaquil

Kansas City to Quito flights

St. Louis to Quito flights

Kansas City to Guayaquil flights

St. Louis to Baltra flights

Kansas City to Cuenca flights

St. Louis to San Cristobal flights

Other flights to Guayaquil

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$625+ Cheap flights from St. Louis (STL) to Guayaquil (GYE)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/16. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Guayaquil with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from St. Louis to Guayaquil

Round-trip from

Find flight deals from St. Louis to Guayaquil

Cheapest flights from St. Louis to GuayaquilExplore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Guayaquil that are best for you.

Best time to book a flight from St. Louis to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from St. Louis with our price prediction graph.

Reviews of airlines servicing Guayaquil

See what other customers who have flown with Delta, LATAM Airlines, and United Airlines from St. Louis to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from St. Louis to Guayaquil round-trip?

Can I find deals for flights from St. Louis to Guayaquil that include hotel bookings?

How can I find direct flights from St. Louis to Guayaquil?

Can I find deals for business class flights from St. Louis to Guayaquil?

What is the cheapest month to book a flight from St. Louis to Guayaquil?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from St. Louis to Guayaquil
Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.