$184+ Cheap flights from Guayaquil (GYE) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — PTY
Nov 23 — Nov 301
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Guayaquil to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl are usually found in May or April, booked 45 days in advance, depart on a Thursday or Tuesday and return on a Sunday
Cheap flight deals from Guayaquil to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Guayaquil to Panama CityExplore the most affordable flight options available from Guayaquil to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2026.
Explore the most affordable flight options available from Guayaquil to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2026.
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:10 am -
1 stop8h 05m
Wed 10/284:10 pm -
1 stop7h 25m
Deal found 10/23![Avianca logo]()
$319
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:35 pm -
1 stop5h 45m
Mon 11/22:30 am -
1 stop6h 30m
Deal found 10/23![Avianca logo]()
$321
This Avianca deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/73:30 am -
1 stop11h 45m
Mon 12/1410:05 am -
1 stop13h 30m
Deal found 10/22![Avianca logo]()
$323
This Copa Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:38 pm -
Nonstop2h 12m
Sun 11/299:24 pm -
Nonstop2h 16m
Deal found 10/23![Copa Airlines logo]()
$324
This Avianca deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:10 am -
1 stop8h 05m
Sun 11/1510:05 am -
2 stops10h 25m
Deal found 10/24![Avianca logo]()
$325
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:40 pm -
2 stops8h 40m
Tue 11/172:30 am -
2 stops9h 15m
Deal found 10/23![Avianca logo]()
$327
This Avianca deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/223:30 am -
1 stop5h 40m
Sun 11/2910:05 am -
2 stops10h 25m
Deal found 10/22![Avianca logo]()
$330
This Avianca deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:35 pm -
1 stop5h 45m
Sat 12/122:30 am -
2 stops9h 55m
Deal found 10/22![Avianca logo]()
$331
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:30 am -
2 stops8h 45m
Tue 11/1010:05 am -
1 stop8h 20m
Deal found 10/23![Avianca logo]()
$333
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:40 pm -
2 stops8h 40m
Wed 12/24:10 pm -
1 stop7h 25m
Deal found 10/23![Avianca logo]()
$339
This Avianca deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:40 pm -
2 stops8h 40m
Mon 11/232:30 am -
2 stops9h 15m
Deal found 10/24![Avianca logo]()
$340
Best flights from Guayaquil to Panama CityDiscover carefully curated flight deals from Guayaquil to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 24, 2026.
Discover carefully curated flight deals from Guayaquil to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 24, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:38 pm -
Nonstop2h 12m
Sun 11/299:24 pm -
Nonstop2h 16m
Deal found 10/24![Copa Airlines logo]()
$324
This Copa Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/82:45 pm -
Nonstop2h 16m
Mon 12/1411:27 am -
Nonstop2h 15m
Deal found 10/22![Copa Airlines logo]()
$339
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/1412:22 pm -
Nonstop2h 17m
Mon 1/186:40 pm -
Nonstop2h 19m
Deal found 10/19![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:38 pm -
Nonstop2h 12m
Sat 11/76:40 pm -
Nonstop2h 16m
Deal found 10/19![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1312:25 pm -
Nonstop2h 15m
Mon 11/169:02 am -
Nonstop2h 16m
Deal found 10/19![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:25 am -
Nonstop2h 14m
Thu 11/269:24 pm -
Nonstop2h 16m
Deal found 10/22![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:25 pm -
Nonstop2h 15m
Sun 11/153:19 pm -
Nonstop2h 16m
Deal found 10/21![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1312:25 pm -
Nonstop2h 15m
Fri 11/209:39 pm -
Nonstop2h 16m
Deal found 10/19![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/56:34 pm -
Nonstop2h 16m
Mon 1/119:24 pm -
Nonstop2h 19m
Deal found 10/21![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1612:25 pm -
Nonstop2h 15m
Thu 11/193:19 pm -
Nonstop2h 16m
Deal found 10/19![Copa Airlines logo]()
$365
Last-minute flights from Guayaquil to Panama CityDiscover last-minute flight deals from Guayaquil to Panama City. Data last updated October 24, 2026 and is based on user searches.
Discover last-minute flight deals from Guayaquil to Panama City. Data last updated October 24, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:35 pm -
1 stop13h 35m
Fri 10/302:30 am -
2 stops9h 15m
Deal found 10/22![Avianca logo]()
$342
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:10 am -
1 stop8h 05m
Wed 10/284:10 pm -
1 stop7h 25m
Deal found 10/23![Avianca logo]()
$319
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:35 pm -
1 stop5h 45m
Mon 11/22:30 am -
1 stop6h 30m
Deal found 10/23![Avianca logo]()
$321
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:30 am -
2 stops8h 45m
Tue 11/1010:05 am -
1 stop8h 20m
Deal found 10/23![Avianca logo]()
$333
This Avianca deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:10 am -
1 stop8h 05m
Sun 11/1510:05 am -
2 stops10h 25m
Deal found 10/24![Avianca logo]()
$325
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:40 pm -
2 stops8h 40m
Tue 11/172:30 am -
2 stops9h 15m
Deal found 10/23![Avianca logo]()
$327
This Avianca deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:40 pm -
2 stops8h 40m
Mon 11/232:30 am -
2 stops9h 15m
Deal found 10/24![Avianca logo]()
$340
This Avianca deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/223:30 am -
1 stop5h 40m
Sun 11/2910:05 am -
2 stops10h 25m
Deal found 10/22![Avianca logo]()
$330
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/223:30 am -
1 stop13h 45m
Thu 11/264:10 pm -
1 stop7h 25m
Deal found 10/21![Avianca logo]()
$345
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:40 pm -
2 stops8h 40m
Wed 12/24:10 pm -
1 stop7h 25m
Deal found 10/23![Avianca logo]()
$339
This Copa Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:38 pm -
Nonstop2h 12m
Sun 11/299:24 pm -
Nonstop2h 16m
Deal found 10/23![Copa Airlines logo]()
$324
One-way flights from Guayaquil to Panama CitySearch for one-way flight options from Guayaquil to Panama City. Find affordable one-way fares based on user searches. Data last updated October 24, 2026.
Search for one-way flight options from Guayaquil to Panama City. Find affordable one-way fares based on user searches. Data last updated October 24, 2026.
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:35 pm -
1 stop5h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Avianca logo]()
$184
This Super.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:54 am -
Nonstop2h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Copa Airlines logo]()
$185
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2812:25 pm -
Nonstop2h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Copa Airlines logo]()
$188
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/63:30 am -
1 stop5h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Avianca logo]()
$195
This Super.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:45 pm -
Nonstop2h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Copa Airlines logo]()
$205
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:38 pm -
Nonstop2h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Copa Airlines logo]()
$209
This Avianca deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1410:10 am -
1 stop15h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Avianca logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:23 pm -
Nonstop2h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Copa Airlines logo]()
$228
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:23 pm -
Nonstop2h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Copa Airlines logo]()
$229
Find flight deals from Guayaquil to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $319 (Avianca) |
One-way from | $184 (Avianca) |
Popular in | December |
Cheapest in | May |
Average price | $356 |
Good round-trip deal | $382 or less |
Good one-way deal | $309 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Guayaquil to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 24, 2026.
Use the filters below to find and compare flights from Guayaquil to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Wed 11/18
10:10 am-5:15 pm
1 stop7h 05m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$184
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Sun 11/8
9:10 am-3:15 pm
1 stop6h 05m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$184
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Thu 11/12
12:25 pm-2:40 pm
Nonstop2h 15m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$185
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Wed 11/18
12:25 pm-2:40 pm
Nonstop2h 15m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
Quickest round-trip
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Sat 11/7
6:38 pm-8:50 pm
Nonstop2h 12m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Wed 12/2
8:23 am-10:39 am
Nonstop2h 16m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Fri 11/13
5:54 am-8:08 am
Nonstop2h 14m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Sat 11/7
4:22 am-6:34 am
Nonstop2h 12m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Thu 1/7
12:22 pm-2:39 pm
Nonstop2h 17m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Wed 1/13
6:34 pm-8:50 pm
Nonstop2h 16m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Guayaquil to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to Panama City in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Guayaquil-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guayaquil-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guayaquil-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Guayaquil-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Guayaquil to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Guayaquil with our price prediction graph.
GYE-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Guayaquil to Panama City
Prices
Airlines
Delays
How far ahead should I book a flight from Guayaquil to Panama City?
The best time to book flights from Guayaquil to Panama City is 44 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Guayaquil to Panama City?
Currently, May is the cheapest month in which you can book a flight from Guayaquil to Panama City (average of $283). Flying from Guayaquil to Panama City in December is currently the most expensive (average of $371). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from GYE to PTY?
Find hourly flight availability from Guayaquil to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 24, 2026.
A simple way to save on the total cost of your ticket is to fly from Guayaquil to Panama City in the afternoon. If you’re flexible enough to do this you can expect to save up to 26% on your trip compared to booking a flight at noon.
What is the cheapest day to fly from Guayaquil to Panama City?
Use this chart to determine the cheapest time to fly round-trip from Guayaquil to Panama City. Price data was last updated on October 24, 2026.
Travelers seeking maximum savings on their Guayaquil to Panama City flight should consider departing on Saturday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
How often are flights from Guayaquil to Panama City delayed?
About 3% of weekly flights between Guayaquil and Panama City have experienced delays in the past year, with the average delay time being 102 minutes.
What is the most punctual flight time for Guayaquil to Panama City flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Thursday tends to have the lowest number of delays on this route, whereas Monday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Guayaquil to Panama City flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 3% of flights being delayed.
The best insider tips for Guayaquil to Panama City flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Guayaquil to Panama City trip
Our travel experts
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 24, 2026.
Read through reviews of airlines operating flights from Guayaquil to Panama City, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
7.8
Comfort
7.4
Crew
8.1
Overall
7.6
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Food
7.0
Boarding
7.8
Comfort
7.4
Crew
8.1
Overall
7.6
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Food
7.0
Boarding
7.8
Comfort
7.4
Crew
8.1
Overall
7.6
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Guayaquil to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Guayaquil
Panama City flight routes
Popular flights
Alternative routes for Guayaquil to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Guayaquil to Panama City by cabin class
Find flights from Guayaquil to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Guayaquil and Panama City flights
Browse other Guayaquil and Panama City flight options. Last updated on October 24, 2026.
Other flights from Guayaquil
Browse through other flights departing from Guayaquil. Flights are based on user searches made on Cheapflights and were last updated on October 24, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Guayaquil to Panama City
Discover the top 2 airlines that operate flights from Guayaquil to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$237 | Average$332 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$273 | Average$369 | FlexibilityNo cancel fee | On-time70% |