$157+ Cheap flights from Guayaquil (GYE) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — PTY
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Find cheap flights from Guayaquil to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl are usually found in May or April, booked 84 days in advance, depart on a Thursday or Saturday and return on a Sunday
Cheap flight deals from Guayaquil to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Guayaquil to Panama CityExplore the most affordable flight options available from Guayaquil to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Guayaquil to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This Avianca deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/269:10 am -
1 stop7h 50m
Tue 9/294:25 am -
1 stop13h 10m
Deal found 9/7![Avianca logo]()
$317
This Avianca deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:45 pm -
1 stop8h 50m
Sun 10/45:55 pm -
1 stop15h 00m
Deal found 9/4![Avianca logo]()
$319
This Avianca deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:35 pm -
1 stop13h 35m
Tue 11/246:10 pm -
1 stop5h 25m
Deal found 9/5![Avianca logo]()
$329
This Avianca deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:50 pm -
1 stop5h 45m
Fri 9/114:25 am -
1 stop13h 10m
Deal found 9/5![Avianca logo]()
$331
This Avianca deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:50 pm -
1 stop5h 45m
Sun 9/205:55 pm -
1 stop15h 00m
Deal found 9/5![Avianca logo]()
$332
This Avianca deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:50 pm -
1 stop14h 25m
Sun 10/184:25 am -
2 stops12h 25m
Deal found 9/4![Avianca logo]()
$339
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:10 am -
1 stop5h 05m
Fri 9/184:25 am -
1 stop13h 10m
Deal found 9/9![Avianca logo]()
$345
This Avianca deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:30 am -
1 stop13h 30m
Sun 10/183:10 pm -
1 stop8h 20m
Deal found 9/5![Avianca logo]()
$348
Best flights from Guayaquil to Panama CityDiscover carefully curated flight deals from Guayaquil to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Guayaquil to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This Avianca deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:35 pm -
1 stop5h 45m
Wed 11/182:30 am -
2 stops9h 15m
Deal found 9/4![Avianca logo]()
$339
This Copa Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:18 pm -
Nonstop2h 16m
Tue 10/276:40 pm -
Nonstop2h 13m
Deal found 9/8![Copa Airlines logo]()
$352
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/42:47 pm -
Nonstop2h 14m
Sun 11/83:19 pm -
Nonstop2h 16m
Deal found 9/4![Copa Airlines logo]()
$364
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:45 pm -
Nonstop2h 16m
Wed 12/96:40 pm -
Nonstop2h 17m
Deal found 9/4![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:30 pm -
Nonstop2h 10m
Fri 10/2311:21 am -
Nonstop2h 12m
Deal found 9/9![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:14 am -
Nonstop2h 11m
Wed 10/76:39 pm -
Nonstop2h 13m
Deal found 9/7![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:28 pm -
Nonstop2h 12m
Sat 9/266:39 pm -
Nonstop2h 13m
Deal found 9/7![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/254:21 am -
Nonstop2h 13m
Sun 1/319:02 am -
Nonstop2h 20m
Deal found 9/5![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:24 pm -
Nonstop2h 15m
Mon 11/3011:27 am -
Nonstop2h 15m
Deal found 9/4![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:30 pm -
Nonstop2h 10m
Tue 10/136:39 pm -
Nonstop2h 13m
Deal found 9/9![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/82:45 pm -
Nonstop2h 16m
Mon 12/1411:27 am -
Nonstop2h 15m
Deal found 9/7![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:28 pm -
Nonstop2h 12m
Sun 9/278:20 am -
Nonstop2h 14m
Deal found 9/6![Copa Airlines logo]()
$365
Last-minute flights from Guayaquil to Panama CityDiscover last-minute flight deals from Guayaquil to Panama City. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Guayaquil to Panama City. Data last updated September 9, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:50 pm -
1 stop5h 45m
Sun 9/2010:10 am -
1 stop4h 25m
Deal found 9/6![Avianca logo]()
$331
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:10 am -
1 stop5h 05m
Fri 9/184:25 am -
1 stop13h 10m
Deal found 9/9![Avianca logo]()
$345
This Avianca deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:50 pm -
1 stop14h 25m
Tue 9/2210:10 am -
1 stop4h 25m
Deal found 9/5![Avianca logo]()
$332
This Avianca deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:50 pm -
1 stop5h 45m
Sun 9/205:55 pm -
1 stop15h 00m
Deal found 9/5![Avianca logo]()
$334
This Avianca deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:50 pm -
1 stop5h 45m
Sun 9/273:10 pm -
1 stop8h 20m
Deal found 9/5![Avianca logo]()
$329
This Avianca deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/269:10 am -
1 stop7h 50m
Tue 9/294:25 am -
1 stop13h 10m
Deal found 9/7![Avianca logo]()
$317
This Avianca deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:50 pm -
1 stop5h 45m
Fri 10/24:25 am -
2 stops11h 30m
Deal found 9/7![Avianca logo]()
$349
This Avianca deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:30 am -
1 stop13h 30m
Mon 10/55:55 pm -
1 stop5h 35m
Deal found 9/5![Avianca logo]()
$319
This Avianca deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:30 am -
1 stop13h 30m
Sun 10/183:10 pm -
1 stop8h 20m
Deal found 9/5![Avianca logo]()
$348
This Avianca deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:50 pm -
1 stop14h 25m
Sun 10/184:25 am -
2 stops12h 25m
Deal found 9/4![Avianca logo]()
$339
One-way flights from Guayaquil to Panama CitySearch for one-way flight options from Guayaquil to Panama City. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Guayaquil to Panama City. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/273:30 am -
1 stop5h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Avianca logo]()
$157
This Copa Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:01 am -
Nonstop2h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Copa Airlines logo]()
$167
This Avianca deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/63:30 am -
1 stop13h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Avianca logo]()
$180
This Avianca deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:50 pm -
1 stop14h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Avianca logo]()
$181
This FlightHub deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:45 pm -
1 stop8h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Avianca logo]()
$183
This Super.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am -
Nonstop2h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Copa Airlines logo]()
$186
This Super.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:45 pm -
1 stop8h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Avianca logo]()
$187
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:33 pm -
Nonstop2h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Copa Airlines logo]()
$188
This Copa Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:40 pm -
Nonstop2h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Copa Airlines logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1912:22 pm -
Nonstop2h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Copa Airlines logo]()
$193
This Avianca deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/163:30 am -
1 stop5h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Avianca logo]()
$195
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:50 pm -
1 stop14h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Avianca logo]()
$196
Find flight deals from Guayaquil to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $317 (Avianca) |
One-way from | $157 (Avianca) |
Popular in | December |
Cheapest in | May |
Average price | $339 |
Good round-trip deal | $409 or less |
Good one-way deal | $350 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Guayaquil to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Guayaquil to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Sat 10/31
6:40 pm-8:50 pm
Nonstop2h 10m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$167
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Wed 10/28
6:01 am-8:12 am
Nonstop2h 11m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$167
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Sat 10/3
12:18 pm-2:34 pm
Nonstop2h 16m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$186
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Mon 9/21
2:37 pm-4:49 pm
Nonstop2h 12m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Sun 9/27
4:13 am-6:25 am
Nonstop2h 12m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Fri 10/9
6:30 pm-8:40 pm
Nonstop2h 10m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Mon 1/11
12:22 pm-2:39 pm
Nonstop2h 17m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Mon 10/19
6:01 am-8:12 am
Nonstop2h 11m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Sun 11/15
7:35 pm-1:20 am
1 stop5h 45m
Panama City Tocumen Intl
Wed 11/18
2:30 am-11:45 am
2 stops9h 15m
$339
GuayaquilPanama City
GYE Guayaquil Jose Joaquin de Olmedo - PTY Panama City Tocumen Intl
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Tue 10/20
12:18 pm-2:34 pm
Nonstop2h 16m
Panama City Tocumen Intl
Tue 10/27
6:40 pm-8:53 pm
Nonstop2h 13m
$352
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Guayaquil to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Guayaquil-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guayaquil-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guayaquil-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Guayaquil-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Guayaquil to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Guayaquil with our price prediction graph.
GYE-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Guayaquil to Panama City
Prices
Airlines
Delays
How far ahead should I book a flight from Guayaquil to Panama City?
The best time to book flights from Guayaquil to Panama City is 83 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Guayaquil to Panama City?
Currently, May is the cheapest month in which you can book a flight from Guayaquil to Panama City (average of $283). Flying from Guayaquil to Panama City in December is currently the most expensive (average of $380). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from GYE to PTY?
Find hourly flight availability from Guayaquil to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 9, 2026.
A simple way to save on the total cost of your ticket is to fly from Guayaquil to Panama City in the afternoon. If you’re flexible enough to do this you can expect to save up to 27% on your trip compared to booking a flight at noon.
What is the cheapest day to fly from Guayaquil to Panama City?
Use this chart to determine the cheapest time to fly round-trip from Guayaquil to Panama City. Price data was last updated on September 5, 2026.
Travelers seeking maximum savings on their Guayaquil to Panama City flight should consider departing on Saturday afternoons when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
How often are flights from Guayaquil to Panama City delayed?
About 3% of weekly flights between Guayaquil and Panama City have experienced delays in the past year, with the average delay time being 105 minutes.
What is the most punctual flight time for Guayaquil to Panama City flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Thursday tends to have the lowest number of delays on this route, whereas Monday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Guayaquil to Panama City flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 3% of flights being delayed.
The best insider tips for Guayaquil to Panama City flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Guayaquil to Panama City trip
Our travel experts
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 9, 2026.
Read through reviews of airlines operating flights from Guayaquil to Panama City, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.9
Crew
8.1
Entertainment
6.9
Boarding
7.8
Overall
7.6
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Crew
8.1
Entertainment
6.9
Boarding
7.8
Overall
7.6
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Crew
8.1
Entertainment
6.9
Boarding
7.8
Overall
7.6
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Guayaquil to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Guayaquil and Panama City flights
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Other flights from Guayaquil
Browse through other flights departing from Guayaquil. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
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Top 2 airlines flying from Guayaquil to Panama City
Discover the top 2 airlines that operate flights from Guayaquil to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$241 | Average$334 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$273 | Average$380 | FlexibilityNo cancel fee | On-time70% |