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Panama City

$143+ Cheap flights from Guayaquil (GYE) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — PTY
Aug 26 — Sep 21
Wed 8/26
Wed 9/2
1 adult, Economy
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Find cheap flights from Guayaquil to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl are usually found in May or April, booked 84 days in advance, depart on a Saturday or Friday and return on a Saturday

Cheap flight deals from Guayaquil to Panama City

Cheapest flights from Guayaquil to Panama City
Explore the most affordable flight options available from Guayaquil to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.

This Avianca deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:05 am
GYE
-
PTY
1 stop6h 55m
Avianca
Thu 9/244:25 am
PTY
-
GYE
1 stop10h 10m
Avianca
Deal found 7/27$297
This Avianca deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:50 pm
GYE
-
PTY
1 stop5h 45m
Avianca
Sun 8/2310:10 am
PTY
-
GYE
1 stop13h 20m
Avianca
Deal found 7/27$307
This Avianca deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:30 am
GYE
-
PTY
1 stop10h 45m
Avianca
Sun 10/1810:10 am
PTY
-
GYE
1 stop7h 25m
Avianca
Deal found 7/26$309
This Avianca deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:50 pm
GYE
-
PTY
1 stop14h 25m
Avianca
Tue 9/2210:10 am
PTY
-
GYE
1 stop4h 25m
Avianca
Deal found 7/26$311
This Avianca deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:50 pm
GYE
-
PTY
1 stop14h 25m
Avianca
Sun 9/204:25 am
PTY
-
GYE
1 stop10h 10m
Avianca
Deal found 7/26$312
This Avianca deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/123:45 pm
GYE
-
PTY
1 stop8h 50m
Avianca
Fri 8/2110:10 am
PTY
-
GYE
1 stop4h 25m
Avianca
Deal found 7/22$313
This Avianca deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/303:30 am
GYE
-
PTY
1 stop10h 45m
Avianca
Mon 8/310:10 am
PTY
-
GYE
1 stop4h 25m
Avianca
Deal found 7/22$314
This Copa Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:37 pm
GYE
-
PTY
Nonstop2h 12m
Copa Airlines
Sun 9/208:20 am
PTY
-
GYE
Nonstop2h 14m
Copa Airlines
Deal found 7/22$317
This Avianca deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:50 pm
GYE
-
PTY
1 stop5h 45m
Avianca
Wed 8/54:25 am
PTY
-
GYE
2 stops11h 55m
Avianca
Deal found 7/26$318
This Avianca deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:30 am
GYE
-
PTY
1 stop13h 30m
Avianca
Mon 10/510:10 am
PTY
-
GYE
1 stop4h 25m
Avianca
Deal found 7/26$319
This Avianca deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:30 am
GYE
-
PTY
1 stop13h 30m
Avianca
Mon 8/104:25 am
PTY
-
GYE
2 stops12h 25m
Avianca
Deal found 7/27$328
This Copa Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:28 am
GYE
-
PTY
Nonstop2h 12m
Copa Airlines
Mon 8/248:20 am
PTY
-
GYE
Nonstop2h 14m
Copa Airlines
Deal found 7/25$329

Find flight deals from Guayaquil to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$297
(Avianca)

One-way from

$143
(Super.com)

Popular in

December

Cheapest in

May

Average price

$317

Good round-trip deal

$328 or less

Good one-way deal

$306 or less
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-Panama City Tocumen Intl flights.
Search Deals
From Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl
Search Deals
One-way flight from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals
Price to beat on a round-trip flight from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl.
Search Deals
Price to beat on a one-way flight from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from Guayaquil to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Fri 11/20

2:47 pm-5:01 pm

Nonstop2h 14m

Panama City Tocumen Intl

Fri 11/27

9:02 am-11:18 am

Nonstop2h 16m

$317
Quickest round-trip

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Tue 9/1

11:48 am-2:00 pm

Nonstop2h 12m

Panama City Tocumen Intl

Sat 9/12

11:21 am-1:34 pm

Nonstop2h 13m

$317

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Thu 10/29

12:23 pm-2:39 pm

Nonstop2h 16m

Panama City Tocumen Intl

Mon 11/2

9:02 am-11:18 am

Nonstop2h 16m

$317

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Fri 8/7

2:37 pm-4:49 pm

Nonstop2h 12m

Panama City Tocumen Intl

Mon 8/10

9:08 am-11:22 am

Nonstop2h 14m

$317

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Sun 9/27

11:48 am-2:00 pm

Nonstop2h 12m

Panama City Tocumen Intl

Wed 10/7

9:08 am-11:21 am

Nonstop2h 13m

$317

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Tue 12/8

2:45 pm-5:01 pm

Nonstop2h 16m

Panama City Tocumen Intl

Mon 12/14

6:40 pm-8:57 pm

Nonstop2h 17m

$317

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Fri 8/21

6:28 pm-8:40 pm

Nonstop2h 12m

Panama City Tocumen Intl

Sat 8/22

9:48 pm-12:02 am

Nonstop2h 14m

$317

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Wed 9/30

12:22 pm-2:34 pm

Nonstop2h 12m

Panama City Tocumen Intl

Sat 10/10

9:48 pm-12:01 am

Nonstop2h 13m

$317

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Sat 10/24

12:18 pm-2:34 pm

Nonstop2h 16m

Panama City Tocumen Intl

Tue 10/27

9:02 am-11:15 am

Nonstop2h 13m

$317

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Mon 11/2

4:22 am-6:34 am

Nonstop2h 12m

Panama City Tocumen Intl

Sat 11/7

9:02 am-11:18 am

Nonstop2h 16m

$317

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/26

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Compare providers for flights from Guayaquil to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to Panama City in July.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Guayaquil-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guayaquil-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guayaquil-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Guayaquil-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Guayaquil to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to Panama City

How far ahead should I book a flight from Guayaquil to Panama City?

The best time to book flights from Guayaquil to Panama City is 83 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Guayaquil to Panama City?

Currently, May is the cheapest month in which you can book a flight from Guayaquil to Panama City (average of $283). Flying from Guayaquil to Panama City in December is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GYE to PTY?

Find hourly flight availability from Guayaquil to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 27, 2026.

A simple way to save on the total cost of your ticket is to fly from Guayaquil to Panama City in the afternoon. If you’re flexible enough to do this you can expect to save up to 27% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Guayaquil to Panama City?

Use this chart to determine the cheapest time to fly round-trip from Guayaquil to Panama City. Price data was last updated on July 25, 2026.

Travelers seeking maximum savings on their Guayaquil to Panama City flight should consider departing on Saturday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Guayaquil to Panama City?

Airfare is typical for this route at the moment.

Guayaquil to Panama City flights typically cost between $287 and $372 in September.
The cheapest round-trip price found within the last 5 days was $297 on Avianca (Sep 16-Sep 24).

The best insider tips for Guayaquil to Panama City flights

AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Guayaquil to Panama City trip
Our travel experts
Harriet Baskas

Harriet Baskas

Expert on United Airlines

Harriet is an award-winning journalist who is happiest in an airport or an unusual museum. Her stories about airports, air travel, and the business of travel have appeared on NBC News, CNBC, USA TODAY, The Points Guy and other outlets. She is the creator of the StuckatTheAirport.com blog and the author of nine books. When not out on the road or exploring the latest airport amenities, she’s home in Seattle getting ready for the next adventure.

Read more
Paul Rubio

Paul Rubio

Expert on Copa Airlines

Travel journalist and photographer Paul Rubio is a Miami native (and current resident), who has lived in nine countries and traveled to 137. He is an expert in luxury travel, eco-travel, loyalty programs, hotels, airports and airlines. He is a contributing editor at AFAR, Condé Nast Traveler, LUXURY Magazine, and Palm Beach Illustrated.

Read more

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 27, 2026.
Read through reviews of airlines operating flights from Guayaquil to Panama City, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,561 reviews

Boarding

7.8

Entertainment

6.8

Overall

7.6

Crew

8.1

Food

6.9

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jul 2026

BOS - PTY

Airline was delayed 1 hour, that made my layover flight be missed, gave wrong information about gates, they closed the gates in my face, rebooked me, and had business class, and rebooked me not business class
Copa Airlines
7.6
Good
1,561 reviews
Copa Airlines
7.6
Good
1,561 reviews

Boarding

7.8

Entertainment

6.8

Overall

7.6

Crew

8.1

Food

6.9

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jul 2026

BOS - PTY

Airline was delayed 1 hour, that made my layover flight be missed, gave wrong information about gates, they closed the gates in my face, rebooked me, and had business class, and rebooked me not business class
Avianca
6.5
Okay
2,522 reviews
Copa Airlines
7.6
Good
1,561 reviews

Boarding

7.8

Entertainment

6.8

Overall

7.6

Crew

8.1

Food

6.9

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jul 2026

BOS - PTY

Airline was delayed 1 hour, that made my layover flight be missed, gave wrong information about gates, they closed the gates in my face, rebooked me, and had business class, and rebooked me not business class

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Guayaquil to Panama City?

    You will need to book a flight from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl if you want to fly from Guayaquil to Panama City. At least 2 different airlines have flights from Jose Joaquin de Olmedo (GYE) to Tocumen Intl (PTY) on a regular basis. There are 16 flights to Panama City from the Guayaquil airport per day. If you manage to book one that is nonstop, then you can expect the flight time from GYE to PTY to be around 2h 10m.

  • How popular is this Guayaquil to Panama City flight route?

    This flight path from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl was viewed by 10 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Guayaquil to Panama City?

    There are many flights that can get you from Guayaquil to Panama City in 2h 12m. Fly via Copa Airlines to get the fastest option. There are 776 mi between Guayaquil and Panama City. All flights are typically nonstop.

  • What are the cheapest airlines flying from Guayaquil to Panama City round-trip?

    Our cheapest airline available from Guayaquil to Panama City is Avianca. Our recent data shows that you can find tickets from as low as $241 on this airline. An additional option worth looking into is Copa Airlines, starting at $273. Avianca is currently priced 28% below the average price you’ll pay for this route.

  • What are the most reliable airlines from Guayaquil to Panama City?

    No one likes to see their flight delayed. When booking a flight from Guayaquil to Panama City consider choosing Copa Airlines (92%), Air France (91%) or KLM (89%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Guayaquil to Panama City?

    Looking at all options, your cheapest flight can be booked for $213. While the most popular route (Guayaquil Jose Joaquin de Olmedo - Panama City Tocumen Intl) can be booked for $315 on average, our data indicates $454 when flying from Guayaquil to Panama City.

  • Can I find deals for flights from Guayaquil to Panama City that include hotel bookings?

    Yes. In addition to deals on Guayaquil to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to Panama City.

  • Can I find deals for business class flights from Guayaquil to Panama City?

    Yes. Cheapflights offers flight deals from Guayaquil to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to Panama City?

    Currently, May is the cheapest month in which you can book a flight from Guayaquil to Panama City (average of $283). Flying from Guayaquil to Panama City in December is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Guayaquil to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Quito to Panama City flights

Top 2 airlines flying from Guayaquil to Panama City

Discover the top 2 airlines that operate flights from Guayaquil to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$241Average$339FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$273Average$384FlexibilityNo cancel feeOn-time70%

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