$816+ Cheap flights from St. Louis (STL) to Cusco (CUZ)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CUZ
Oct 28 — Nov 41
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Cuzco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Cuzco
Cheapest
Best
One-way
Cheapest flights from St. Louis to CuzcoExplore the most affordable flight options available from St. Louis to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 28, 2026.
Explore the most affordable flight options available from St. Louis to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 28, 2026.
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:00 pm -
2 stops18h 00m
Tue 11/173:10 pm -
2 stops25h 40m
Deal found 9/26![American Airlines logo]()
$1,149
This Expedia deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:05 am -
2 stops30h 50m
Mon 11/1612:50 pm -
2 stops21h 10m
Deal found 9/27![LATAM Airlines logo]()
$1,357
This LATAM Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:48 pm -
2 stops17h 22m
Tue 11/175:00 am -
3 stops41h 40m
Deal found 9/26![Multiple Airlines logo]()
$1,666
This Gotogate deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:05 pm -
2 stops18h 20m
Mon 11/165:10 pm -
3 stops29h 30m
Deal found 9/27![Multiple Airlines logo]()
$2,318
This KAYAK deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/277:15 pm -
3 stops26h 15m
Sun 1/310:45 pm -
3 stops25h 54m
Deal found 9/25![LATAM Airlines logo]()
$2,355
Best flights from St. Louis to CuzcoDiscover carefully curated flight deals from St. Louis to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 28, 2026.
Discover carefully curated flight deals from St. Louis to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 28, 2026.
This BusinessClass deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/105:00 am -
2 stops28h 20m
Wed 1/209:30 pm -
2 stops20h 56m
Deal found 9/25![GOL logo]()
$1,107
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:00 pm -
2 stops18h 00m
Tue 11/173:10 pm -
2 stops25h 40m
Deal found 9/26![American Airlines logo]()
$1,149
This Expedia deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:05 am -
2 stops30h 50m
Mon 11/1612:50 pm -
2 stops21h 10m
Deal found 9/27![LATAM Airlines logo]()
$1,357
This LATAM Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:48 pm -
2 stops17h 22m
Tue 11/175:00 am -
3 stops41h 40m
Deal found 9/26![Multiple Airlines logo]()
$1,666
This Gurufare deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1411:19 am -
2 stops23h 06m
Sun 3/214:45 pm -
2 stops24h 48m
Deal found 9/25![GOL logo]()
$1,120
This Ovago deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/147:20 am -
3 stops15h 10m
Sun 3/217:10 am -
2 stops25h 02m
Deal found 9/25![LATAM Airlines logo]()
$1,375
This KAYAK deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/279:52 am -
2 stops21h 08m
Sun 1/311:15 pm -
3 stops25h 24m
Deal found 9/25![LATAM Airlines logo]()
$2,380
This Mytrip deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/144:05 pm -
3 stops23h 50m
Sun 3/215:00 am -
3 stops34h 26m
Deal found 9/25![Multiple Airlines logo]()
$3,053
One-way flights from St. Louis to CuzcoSearch for one-way flight options from St. Louis to Cuzco. Find affordable one-way fares based on user searches. Data last updated September 28, 2026.
Search for one-way flight options from St. Louis to Cuzco. Find affordable one-way fares based on user searches. Data last updated September 28, 2026.
This FlightHub deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:14 am -
2 stops31h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![LATAM Airlines logo]()
$816
This KAYAK deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:30 am -
3 stops23h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$2,533
Find flight deals from St. Louis to Cuzco
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $1,107 (BusinessClass) |
One-way from | $816 (FlightHub) |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 28, 2026.
Use the filters below to find and compare flights from St. Louis to Cusco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Fri 10/9
10:14 am-5:15 pm
2 stops31h 01m
Cusco Velazco Astete
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$816
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Sun 1/10
5:00 am-10:20 am
2 stops28h 20m
Cusco Velazco Astete
Wed 1/20
9:30 pm-5:26 pm
2 stops20h 56m
$1,107
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Sun 3/14
11:19 am-10:25 am
2 stops23h 06m
Cusco Velazco Astete
Sun 3/21
4:45 pm-5:33 pm
2 stops24h 48m
$1,120
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Tue 11/10
5:00 pm-12:00 pm
2 stops18h 00m
Cusco Velazco Astete
Tue 11/17
3:10 pm-3:50 pm
2 stops25h 40m
$1,149
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Wed 11/11
10:05 am-5:55 pm
2 stops30h 50m
Cusco Velazco Astete
Mon 11/16
12:50 pm-9:00 am
2 stops21h 10m
$1,357
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Sun 3/14
7:20 am-10:30 pm
3 stops15h 10m
Cusco Velazco Astete
Sun 3/21
7:10 am-8:12 am
2 stops25h 02m
$1,375
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Tue 11/10
5:48 pm-12:10 pm
2 stops17h 22m
Cusco Velazco Astete
Tue 11/17
5:00 am-9:40 pm
3 stops41h 40m
$1,666
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Sun 12/27
9:52 am-8:00 am
2 stops21h 08m
Cusco Velazco Astete
Sun 1/3
11:15 pm-11:39 pm
3 stops25h 24m
$2,380
Quickest round-trip
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Fri 10/9
8:30 am-8:00 am
3 stops23h 30m
Cusco Velazco Astete
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$2,533
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Sun 3/14
4:05 pm-3:55 pm
3 stops23h 50m
Cusco Velazco Astete
Sun 3/21
5:00 am-3:26 pm
3 stops34h 26m
$3,053
Sorted by cheapest first
Compare providers for flights from St. Louis to Cuzco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Cuzco in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Cusco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Cusco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Cusco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Cusco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Cusco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Cuzco
Have a flexible travel schedule? Discover the best time to fly to Cuzco from St. Louis with our price prediction graph.
STL-CUZ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Cuzco
Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated September 28, 2026.
Read through reviews of airlines operating flights from St. Louis to Cusco, such as LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Overall
7.4
Crew
8.0
Comfort
7.3
Boarding
7.5
Entertainment
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2025
COR - LIM
Food
6.7
Overall
7.4
Crew
8.0
Comfort
7.3
Boarding
7.5
Entertainment
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2025
COR - LIM
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Cuzco flight routes
Flights by cabin class
Other flight options
Other flights from St. Louis
Popular flights
Alternative routes for St. Louis to Cuzco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Cuzco by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Cuzco
Explore flights to Cuzco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 28, 2026.
Search flights from St. Louis to Cuzco by cabin class
Find flights from St. Louis to Cuzco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Cuzco flights
Browse other St. Louis and Cuzco flight options. Last updated on September 28, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on September 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from St. Louis to Cuzco
Discover the top airline that operate flights from St. Louis to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$1,033 | Average$1,271 | FlexibilityNo cancel fee | On-time81% |