$634+ Cheap flights from St. Louis (STL) to Cusco (CUZ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CUZ
Jun 8 — Jun 151
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Cuzco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Cuzco
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to CuzcoExplore the most affordable flight options available from St. Louis to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 9, 2026.
Explore the most affordable flight options available from St. Louis to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 9, 2026.
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:06 am
STL
- CUZ
2 stops20h 19m
American Airlines
Tue 6/23:25 pm
CUZ
- STL
2 stops19h 09m
American Airlines
Deal found 5/5![American Airlines logo]()
$1,182
This LATAM Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/91:30 pm
STL
- CUZ
2 stops18h 25m
LATAM Airlines
Fri 11/137:30 am
CUZ
- STL
2 stops17h 09m
LATAM Airlines
Deal found 5/8![LATAM Airlines logo]()
$1,224
This Mytrip deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/71:05 pm
STL
- CUZ
3 stops35h 55m
Multiple Airlines
Sun 6/148:20 am
CUZ
- STL
3 stops27h 46m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$1,250
This KAYAK deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:08 pm
STL
- CUZ
2 stops36h 48m
GOL
Sat 10/179:42 pm
CUZ
- STL
2 stops25h 33m
GOL
Deal found 5/6![GOL logo]()
$1,252
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:06 am
STL
- CUZ
2 stops19h 09m
American Airlines
Thu 5/285:25 pm
CUZ
- STL
2 stops17h 09m
American Airlines
Deal found 5/5![American Airlines logo]()
$1,274
This Expedia deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:12 pm
STL
- CUZ
2 stops29h 48m
LATAM Airlines
Sun 6/1412:10 pm
CUZ
- STL
2 stops35h 46m
LATAM Airlines
Deal found 5/8![LATAM Airlines logo]()
$1,275
This Expedia deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:24 pm
STL
- CUZ
2 stops23h 56m
LATAM Airlines
Sat 7/410:45 pm
CUZ
- STL
2 stops37h 49m
LATAM Airlines
Deal found 5/7![LATAM Airlines logo]()
$1,280
This FlightHub deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:01 pm
STL
- CUZ
2 stops14h 59m
LATAM Airlines
Thu 5/288:25 am
CUZ
- STL
2 stops15h 34m
LATAM Airlines
Deal found 5/7![LATAM Airlines logo]()
$1,327
This KAYAK deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:58 pm
STL
- CUZ
2 stops20h 22m
LATAM Airlines
Mon 8/1011:20 pm
CUZ
- STL
2 stops24h 38m
LATAM Airlines
Deal found 5/4![LATAM Airlines logo]()
$1,344
Best flights from St. Louis to CuzcoDiscover carefully curated flight deals from St. Louis to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 9, 2026.
Discover carefully curated flight deals from St. Louis to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 9, 2026.
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:06 am
STL
- CUZ
2 stops20h 19m
American Airlines
Tue 6/24:30 pm
CUZ
- STL
2 stops18h 04m
American Airlines
Deal found 5/4![American Airlines logo]()
$1,182
This KAYAK deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:08 pm
STL
- CUZ
2 stops36h 48m
GOL
Sat 10/179:42 pm
CUZ
- STL
2 stops25h 33m
GOL
Deal found 5/6![GOL logo]()
$1,252
This Expedia deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:24 pm
STL
- CUZ
2 stops23h 56m
LATAM Airlines
Sat 7/410:45 pm
CUZ
- STL
2 stops37h 49m
LATAM Airlines
Deal found 5/7![LATAM Airlines logo]()
$1,280
This KAYAK deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:58 pm
STL
- CUZ
2 stops20h 22m
LATAM Airlines
Mon 8/1011:20 pm
CUZ
- STL
2 stops24h 38m
LATAM Airlines
Deal found 5/4![LATAM Airlines logo]()
$1,344
This KAYAK deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:08 pm
STL
- CUZ
2 stops12h 18m
GOL
Sat 10/179:42 pm
CUZ
- STL
2 stops25h 33m
GOL
Deal found 5/9![GOL logo]()
$1,370
Last-minute flights from St. Louis to CuzcoDiscover last-minute flight deals from St. Louis to Cuzco. Data last updated May 9, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Cuzco. Data last updated May 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:06 am
STL
- CUZ
2 stops19h 09m
American Airlines
Thu 5/285:25 pm
CUZ
- STL
2 stops17h 09m
American Airlines
Deal found 5/5![American Airlines logo]()
$1,274
This FlightHub deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:01 pm
STL
- CUZ
2 stops14h 59m
LATAM Airlines
Thu 5/288:25 am
CUZ
- STL
2 stops15h 34m
LATAM Airlines
Deal found 5/7![LATAM Airlines logo]()
$1,327
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:06 am
STL
- CUZ
2 stops20h 19m
American Airlines
Tue 6/23:25 pm
CUZ
- STL
2 stops19h 09m
American Airlines
Deal found 5/5![American Airlines logo]()
$1,182
This Mytrip deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/71:05 pm
STL
- CUZ
3 stops35h 55m
Multiple Airlines
Sun 6/148:20 am
CUZ
- STL
3 stops27h 46m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$1,250
This Expedia deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:12 pm
STL
- CUZ
2 stops29h 48m
LATAM Airlines
Sun 6/1412:10 pm
CUZ
- STL
2 stops35h 46m
LATAM Airlines
Deal found 5/8![LATAM Airlines logo]()
$1,275
This Expedia deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:24 pm
STL
- CUZ
2 stops23h 56m
LATAM Airlines
Sat 7/410:45 pm
CUZ
- STL
2 stops37h 49m
LATAM Airlines
Deal found 5/7![LATAM Airlines logo]()
$1,280
This Mytrip deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/272:15 pm
STL
- CUZ
3 stops21h 05m
Multiple Airlines
Sat 7/46:50 am
CUZ
- STL
3 stops31h 12m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$1,878
One-way flights from St. Louis to CuzcoSearch for one-way flight options from St. Louis to Cuzco. Find affordable one-way fares based on user searches. Data last updated May 9, 2026.
Search for one-way flight options from St. Louis to Cuzco. Find affordable one-way fares based on user searches. Data last updated May 9, 2026.
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:08 pm
STL
- CUZ
2 stops17h 36m
American Airlines
Deal found 5/4![American Airlines logo]()
$634
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:20 am
STL
- CUZ
2 stops17h 40m
Delta
Deal found 5/5![Delta logo]()
$674
This BusinessClass deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am
STL
- CUZ
3 stops19h 00m
LATAM Airlines
Deal found 5/5![LATAM Airlines logo]()
$711
Find flight deals from St. Louis to Cuzco
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 9, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $1,182 (American Airlines) |
One-way from | $634 (American Airlines) |
Popular in | August |
Cheapest in | December |
Average price | $1,183 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 9, 2026.
Use the filters below to find and compare flights from St. Louis to Cusco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCusco
STL - CUZ
STLCUZ
Lambert-St Louis
Tue 5/19
11:06 am-7:25 am
2 stops20h 19m
Cusco Velazco Astete
Tue 6/2
4:30 pm-10:34 am
2 stops18h 04m
$1,182
St. LouisCusco
STL - CUZ
STLCUZ
Lambert-St Louis
Sat 10/10
6:08 pm-6:56 am
2 stops36h 48m
Cusco Velazco Astete
Sat 10/17
9:42 pm-11:15 pm
2 stops25h 33m
$1,252
St. LouisCusco
STL - CUZ
STLCUZ
Lambert-St Louis
Sat 6/27
5:24 pm-5:20 pm
2 stops23h 56m
Cusco Velazco Astete
Sat 7/4
10:45 pm-12:34 pm
2 stops37h 49m
$1,280
St. LouisCusco
STL - CUZ
STLCUZ
Lambert-St Louis
Sun 8/2
6:58 pm-3:20 pm
2 stops20h 22m
Cusco Velazco Astete
Mon 8/10
11:20 pm-11:58 pm
2 stops24h 38m
$1,344
Quickest round-trip
St. LouisCusco
STL - CUZ
STLCUZ
Lambert-St Louis
Thu 10/8
6:08 pm-6:26 am
2 stops12h 18m
Cusco Velazco Astete
Sat 10/17
9:42 pm-11:15 pm
2 stops25h 33m
$1,370
Cheapest one-way
Quickest one-way
St. LouisCusco
STL - CUZ
STLCUZ
Lambert-St Louis
Fri 10/9
6:08 pm-11:44 am
2 stops17h 36m
$634
St. LouisCusco
STL - CUZ
STLCUZ
Lambert-St Louis
Fri 10/9
7:20 am-1:00 am
2 stops17h 40m
$674
St. LouisCusco
STL - CUZ
STLCUZ
Lambert-St Louis
Fri 10/9
6:00 am-1:00 am
3 stops19h 00m
$711
Sorted by cheapest first
Compare providers for flights from St. Louis to Cuzco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Cuzco in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Cusco flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on St. Louis-Cusco flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from St. Louis-Cusco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Cusco flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Cusco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Cuzco
Have a flexible travel schedule? Discover the best time to fly to Cuzco from St. Louis with our price prediction graph.
STL-CUZ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Cusco
Reviews of airlines servicing Cuzco
Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated May 9, 2026.
Read through reviews of airlines operating flights from St. Louis to Cusco, such as LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Boarding
7.5
Entertainment
7.0
Overall
7.4
Crew
8.0
Food
6.7
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2025
MIA - GRU
Comfort
7.3
Boarding
7.5
Entertainment
7.0
Overall
7.4
Crew
8.0
Food
6.7
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2025
MIA - GRU
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Cuzco by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Cuzco
Explore flights to Cuzco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 9, 2026.
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St. Louis and Cuzco flights
Browse other St. Louis and Cuzco flight options. Last updated on May 9, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on May 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from St. Louis to Cuzco
Discover the top airline that operate flights from St. Louis to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$919 | Average$1,161 | FlexibilityNo cancel fee | On-time81% |