$649+ Cheap flights from St. Louis (STL) to Cusco (CUZ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CUZ
Sep 9 — Sep 161
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Cuzco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Cuzco
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to CuzcoExplore the most affordable flight options available from St. Louis to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
Explore the most affordable flight options available from St. Louis to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
This Expedia deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:05 pm -
2 stops21h 25m
Sat 12/1211:15 pm -
2 stops41h 11m
Deal found 8/9![Multiple Airlines logo]()
$852
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:40 pm -
3 stops34h 20m
Mon 9/288:20 am -
3 stops36h 00m
Deal found 8/7![Multiple Airlines logo]()
$1,140
This Ovago deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:50 pm -
2 stops18h 30m
Tue 9/155:10 pm -
2 stops17h 00m
Deal found 8/5![Avianca logo]()
$1,168
This oojo deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2012:00 pm -
2 stops18h 10m
Sun 9/2710:05 pm -
2 stops25h 37m
Deal found 8/6![LATAM Airlines logo]()
$1,172
This Gurufare deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:35 am -
2 stops29h 57m
Mon 9/144:05 pm -
2 stops24h 10m
Deal found 8/5![GOL logo]()
$1,184
This FlightHub deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:30 pm -
2 stops21h 40m
Tue 9/298:35 am -
2 stops15h 07m
Deal found 8/8![LATAM Airlines logo]()
$1,206
This LATAM Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:38 pm -
2 stops14h 27m
Thu 11/511:20 am -
2 stops22h 57m
Deal found 8/5![LATAM Airlines logo]()
$1,214
This LATAM Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:50 am -
2 stops13h 10m
Wed 12/98:40 am -
2 stops16h 16m
Deal found 8/6![LATAM Airlines logo]()
$1,241
This BusinessClass deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/304:40 pm -
2 stops14h 55m
Thu 1/712:05 am -
3 stops24h 34m
Deal found 8/8![LATAM Airlines logo]()
$1,282
Best flights from St. Louis to CuzcoDiscover carefully curated flight deals from St. Louis to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
Discover carefully curated flight deals from St. Louis to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:40 pm -
3 stops34h 20m
Mon 9/288:20 am -
3 stops36h 00m
Deal found 8/7![Multiple Airlines logo]()
$1,140
This Ovago deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:50 pm -
2 stops18h 30m
Tue 9/155:10 pm -
2 stops17h 00m
Deal found 8/5![Avianca logo]()
$1,168
This oojo deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2012:00 pm -
2 stops18h 10m
Sun 9/2710:05 pm -
2 stops25h 37m
Deal found 8/6![LATAM Airlines logo]()
$1,172
This Gurufare deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:35 am -
2 stops29h 57m
Mon 9/144:05 pm -
2 stops24h 10m
Deal found 8/5![GOL logo]()
$1,184
This FlightHub deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:30 pm -
2 stops21h 40m
Tue 9/298:35 am -
2 stops15h 07m
Deal found 8/8![LATAM Airlines logo]()
$1,206
This LATAM Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:50 am -
2 stops13h 10m
Sat 12/1210:40 pm -
3 stops47h 33m
Deal found 8/9![Multiple Airlines logo]()
$1,248
This KAYAK deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3011:39 am -
2 stops22h 09m
Fri 1/84:31 pm -
2 stops25h 53m
Deal found 8/6![GOL logo]()
$1,318
This LATAM Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:38 pm -
2 stops14h 27m
Thu 11/511:20 am -
2 stops22h 57m
Deal found 8/5![LATAM Airlines logo]()
$1,214
This LATAM Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:50 am -
2 stops13h 10m
Wed 12/98:40 am -
2 stops16h 16m
Deal found 8/8![LATAM Airlines logo]()
$1,241
This BusinessClass deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/304:40 pm -
2 stops14h 55m
Fri 1/84:15 pm -
3 stops26h 46m
Deal found 8/6![LATAM Airlines logo]()
$1,322
Last-minute flights from St. Louis to CuzcoDiscover last-minute flight deals from St. Louis to Cuzco. Data last updated August 10, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Cuzco. Data last updated August 10, 2026 and is based on user searches.
This Ovago deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:50 pm -
2 stops18h 30m
Tue 9/155:10 pm -
2 stops17h 00m
Deal found 8/5![Avianca logo]()
$1,168
This Gurufare deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:35 am -
2 stops29h 57m
Mon 9/144:05 pm -
2 stops24h 10m
Deal found 8/5![GOL logo]()
$1,184
This BusinessClass deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:40 am -
3 stops23h 20m
Tue 9/155:10 pm -
2 stops27h 10m
Deal found 8/5![Multiple Airlines logo]()
$1,562
This oojo deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2012:00 pm -
2 stops18h 10m
Sun 9/2710:05 pm -
2 stops25h 37m
Deal found 8/6![LATAM Airlines logo]()
$1,172
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:40 pm -
3 stops34h 20m
Mon 9/288:20 am -
3 stops36h 00m
Deal found 8/7![Multiple Airlines logo]()
$1,140
This FlightHub deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:30 pm -
2 stops21h 40m
Tue 9/298:35 am -
2 stops15h 07m
Deal found 8/8![LATAM Airlines logo]()
$1,206
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:00 am -
2 stops25h 32m
Tue 9/297:20 pm -
3 stops17h 43m
Deal found 8/8![American Airlines logo]()
$1,555
One-way flights from St. Louis to CuzcoSearch for one-way flight options from St. Louis to Cuzco. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
Search for one-way flight options from St. Louis to Cuzco. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:07 pm -
2 stops21h 43m
Deal found 8/9![American Airlines logo]()
$649
This FlightHub deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:10 pm -
2 stops23h 10m
Deal found 8/5![Multiple Airlines logo]()
$664
This BusinessClass deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
3 stops17h 25m
Deal found 8/7![LATAM Airlines logo]()
$776
Find flight deals from St. Louis to Cuzco
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $1,140 (Mytrip) |
One-way from | $664 (Justfly.com) |
Popular in | August |
Cheapest in | March |
Average price | $1,369 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from St. Louis to Cusco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Mon 9/21
2:40 pm-1:00 am
3 stops34h 20m
Cusco Velazco Astete
Mon 9/28
8:20 am-8:20 pm
3 stops36h 00m
$1,140
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Sat 9/5
4:50 pm-11:20 am
2 stops18h 30m
Cusco Velazco Astete
Tue 9/15
5:10 pm-10:10 am
2 stops17h 00m
$1,168
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Sun 9/20
12:00 pm-6:10 am
2 stops18h 10m
Cusco Velazco Astete
Sun 9/27
10:05 pm-11:42 pm
2 stops25h 37m
$1,172
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Sat 9/5
11:35 am-5:32 pm
2 stops29h 57m
Cusco Velazco Astete
Mon 9/14
4:05 pm-4:15 pm
2 stops24h 10m
$1,184
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Wed 9/23
2:30 pm-12:10 pm
2 stops21h 40m
Cusco Velazco Astete
Tue 9/29
8:35 am-11:42 pm
2 stops15h 07m
$1,206
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Mon 11/2
5:38 pm-9:05 am
2 stops14h 27m
Cusco Velazco Astete
Thu 11/5
11:20 am-9:17 am
2 stops22h 57m
$1,214
Quickest round-trip
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Sat 12/5
10:50 am-1:00 am
2 stops13h 10m
Cusco Velazco Astete
Wed 12/9
8:40 am-11:56 pm
2 stops16h 16m
$1,241
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Sat 12/5
10:50 am-1:00 am
2 stops13h 10m
Cusco Velazco Astete
Sat 12/12
10:40 pm-9:13 pm
3 stops47h 33m
$1,248
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Wed 12/30
11:39 am-10:48 am
2 stops22h 09m
Cusco Velazco Astete
Fri 1/8
4:31 pm-5:24 pm
2 stops25h 53m
$1,318
St. LouisCusco
STL Lambert-St Louis - CUZ Cusco Velazco Astete
STLCUZ
Lambert-St Louis
Wed 12/30
4:40 pm-8:35 am
2 stops14h 55m
Cusco Velazco Astete
Fri 1/8
4:15 pm-6:01 pm
3 stops26h 46m
$1,322
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Cuzco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Cuzco in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Cusco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Cusco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Cusco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Cusco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Cusco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Cuzco
Have a flexible travel schedule? Discover the best time to fly to Cuzco from St. Louis with our price prediction graph.
STL-CUZ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Cuzco
Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated August 10, 2026.
Read through reviews of airlines operating flights from St. Louis to Cusco, such as LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.4
Entertainment
7.0
Food
6.7
Boarding
7.5
Comfort
7.3
Crew
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2025
COR - LIM
Overall
7.4
Entertainment
7.0
Food
6.7
Boarding
7.5
Comfort
7.3
Crew
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2025
COR - LIM
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Other flights to Cuzco
Explore flights to Cuzco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 10, 2026.
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St. Louis and Cuzco flights
Browse other St. Louis and Cuzco flight options. Last updated on August 10, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on August 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from St. Louis to Cuzco
Discover the top airline that operate flights from St. Louis to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$988 | Average$1,183 | FlexibilityNo cancel fee | On-time81% |