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$365+ Cheap flights from Columbia, MO to San Francisco (COU - SFO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
COU — SFO
Jul 21 — Jul 281
Mon 7/21
Mon 7/28
1 adult, Economy
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Cheap flight deals from Columbia to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 16, 2025.

Round-trip from

$365
(American Airlines)

Popular in

August

Cheapest in

April

Average price

$451
From Columbia Regional to San Francisco
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($143 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($54 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
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Find flight deals from Columbia to San Francisco

Cheapest flights from Columbia to San Francisco
Explore the most affordable flight options available from Columbia to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 16, 2025.

This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:16 pmCOU - SFO
1 stop18h 08mAmerican Airlines
Tue 10/76:10 amSFO - COU
1 stop11h 12mAmerican Airlines
Deal found 7/14$365
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/38:00 amCOU - SFO
1 stop9h 30mUnited Airlines
Tue 10/75:15 amSFO - COU
1 stop7h 02mUnited Airlines
Deal found 7/15$368

Cheapflights Fare Finder

Customize your flight search to find flights from Columbia to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 16, 2025.
Use the filters below to find and compare flights from Columbia to San Francisco that are best for you.

Fly from

Columbia

Fly to

San Francisco

Route

Depart

Return

Price

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Fri 10/3

5:16 pm-9:24 am

1 stop18h 08m

San Francisco

Tue 10/7

6:10 am-7:22 pm

1 stop11h 12m

$365

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Fri 10/3

8:00 am-3:30 pm

1 stop9h 30m

San Francisco

Tue 10/7

5:15 am-2:17 pm

1 stop7h 02m

$368

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Tue 8/19

7:27 am-12:58 pm

1 stop7h 31m

$380

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/15

Best time to book a flight from Columbia to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to San Francisco

What is the cheapest month to book a flight from Columbia, Missouri to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Columbia, Missouri to San Francisco (average of $276). Flying from Columbia, Missouri to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from COU to SFO?

Find hourly flight availability from Columbia to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 16, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 13% on flights from Columbia, Missouri to San Francisco by exploring options for tickets in the morning.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated July 16, 2025.
Get a feel of what it's like to fly with United Airlines and American Airlines from Columbia to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,863 reviews

Comfort

7.3

Crew

8.1

Entertainment

7.0

Overall

7.4

Boarding

7.7

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Apr 2025

TPE - SFO

The boarding experience was okay. The dietary food choices were limited, the midway snacks were hard and dry. The seat was uncomfortable - stiff seat cushion, seat back kept springing back to the upright position, narrow seat width. Love the app and the ability to track my luggage. Flight crew was efficient.
United Airlines
7.4
Good
8,863 reviews
United Airlines
7.4
Good
8,863 reviews

Comfort

7.3

Crew

8.1

Entertainment

7.0

Overall

7.4

Boarding

7.7

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Apr 2025

TPE - SFO

The boarding experience was okay. The dietary food choices were limited, the midway snacks were hard and dry. The seat was uncomfortable - stiff seat cushion, seat back kept springing back to the upright position, narrow seat width. Love the app and the ability to track my luggage. Flight crew was efficient.
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,863 reviews

Comfort

7.3

Crew

8.1

Entertainment

7.0

Overall

7.4

Boarding

7.7

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Apr 2025

TPE - SFO

The boarding experience was okay. The dietary food choices were limited, the midway snacks were hard and dry. The seat was uncomfortable - stiff seat cushion, seat back kept springing back to the upright position, narrow seat width. Love the app and the ability to track my luggage. Flight crew was efficient.

Related info for your journey

Find useful and relevant information for your journey from Columbia to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Columbia, Missouri to San Francisco round-trip?

    Currently priced at $365, American Airlines will fly you from Columbia, Missouri to San Francisco and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $368. American Airlines is 35% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Columbia to San Francisco that include hotel bookings?

    Yes. In addition to deals on Columbia to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to San Francisco.

  • Can I find deals for business class flights from Columbia to San Francisco?

    Yes. Cheapflights offers flight deals from Columbia to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Columbia, Missouri to San Francisco (average of $276). Flying from Columbia, Missouri to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Mountain View
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Livermore
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Manteca
Antioch
Hollister
Watsonville
Newark
Milpitas
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Santa Clara
Richmond

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Top airline flying from Columbia to San Francisco

Discover the top airline that operate flights from Columbia to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$377Average$528FlexibilityNo cancel feeOn-time71%

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