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$358+ Cheap flights from Columbia, MO to San Francisco (COU - SFO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/26. Fares are subject to change and may not be available on all flights or dates of travel.
COU — SFO
5月 28 — 6月 41
週四 5/28
週四 6/4
1 adult, Economy
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Cheap flight deals from Columbia to San Francisco

Cheapest flights from Columbia to San Francisco
Explore the most affordable flight options available from Columbia to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 4月 28, 2026.

This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週五 6/267:39 pm
COU
-
SFO
1 stop7h 09m
American Airlines
週一 6/2911:10 pm
SFO
-
COU
1 stop8h 56m
American Airlines
Deal found 4/27$358
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週二 7/711:45 am
COU
-
SFO
2 stops9h 24m
American Airlines
週六 7/115:30 am
SFO
-
COU
1 stop9h 17m
American Airlines
Deal found 4/25$364
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週五 6/269:14 am
COU
-
SFO
1 stop6h 55m
United Airlines
週日 6/2812:50 am
SFO
-
COU
1 stop7h 58m
United Airlines
Deal found 4/23$375
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週六 5/912:06 pm
COU
-
SFO
1 stop7h 33m
American Airlines
週三 5/1310:06 am
SFO
-
COU
1 stop7h 07m
American Airlines
Deal found 4/24$408

Find flight deals from Columbia to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 4月 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$358
(American Airlines)

Popular in

September

Cheapest in

March

Average price

$362
Provider with most accurate pricing for Columbia Regional-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbia Regional-San Francisco flights.
Search Deals
From Columbia Regional to San Francisco
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($51 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated 4月 28, 2026.
Use the filters below to find and compare flights from Columbia to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

週五 6/26

9:14 am-2:09 pm

1 stop6h 55m

San Francisco

週日 6/28

12:50 am-10:48 am

1 stop7h 58m

$375

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

週二 5/12

9:00 am-3:31 pm

1 stop8h 31m

San Francisco

週六 5/16

12:00 pm-8:49 pm

1 stop6h 49m

$408

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

週二 7/7

11:45 am-7:09 pm

2 stops9h 24m

San Francisco

週六 7/11

5:50 am-4:47 pm

2 stops8h 57m

$432

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

週三 8/19

7:10 am-2:38 pm

1 stop9h 28m

San Francisco

週一 8/24

6:36 am-4:46 pm

1 stop8h 10m

$447

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

週二 5/12

12:06 pm-7:04 pm

2 stops8h 58m

San Francisco

週六 5/16

6:00 am-4:51 pm

2 stops8h 51m

$481

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

週六 8/29

11:48 am-7:25 pm

2 stops9h 37m

San Francisco

週四 9/3

6:36 am-4:46 pm

1 stop8h 10m

$502

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

週三 5/13

11:30 am-5:12 pm

1 stop7h 42m

San Francisco

週日 5/17

11:56 pm-10:55 am

1 stop8h 59m

$508

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

週六 5/9

11:30 am-7:32 pm

1 stop10h 02m

San Francisco

週三 5/13

12:00 pm-8:49 pm

1 stop6h 49m

$508

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

週三 5/13

10:16 am-11:59 pm

1 stop15h 43m

San Francisco

週五 5/15

11:28 pm-3:58 pm

1 stop14h 30m

$508

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

週五 6/26

5:19 pm-11:21 pm

1 stop8h 02m

San Francisco

週一 6/29

5:40 am-4:49 pm

2 stops9h 09m

$542

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/27

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Compare providers for flights from Columbia to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbia to San Francisco in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Columbia, Missouri-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbia, Missouri-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbia, Missouri-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Columbia, Missouri-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbia, Missouri-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Columbia to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to San Francisco

What is the cheapest month to book a flight from Columbia, Missouri to San Francisco?

Currently, March is the cheapest month in which you can book a flight from Columbia, Missouri to San Francisco (average of $298). Flying from Columbia, Missouri to San Francisco in September is currently the most expensive (average of $791). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Columbia, Missouri to San Francisco?

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated 4月 28, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Columbia to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,672 reviews

Entertainment

7.1

Boarding

7.7

Crew

8.1

Overall

7.4

Food

6.6

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
United Airlines
7.4
Good
9,672 reviews
United Airlines
7.4
Good
9,672 reviews

Entertainment

7.1

Boarding

7.7

Crew

8.1

Overall

7.4

Food

6.6

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
American Airlines
7.1
Good
11,677 reviews
United Airlines
7.4
Good
9,672 reviews

Entertainment

7.1

Boarding

7.7

Crew

8.1

Overall

7.4

Food

6.6

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.

Related info for your journey

Find useful and relevant information for your journey from Columbia to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbia, Missouri to San Francisco?

    United Airlines and American Airlines can get you from Columbia, Missouri to San Francisco in just under 6h 55m. Your travel time can differ by up to 2h 29m. Columbia, Missouri and San Francisco are separated by a distance of 1631 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Columbia, Missouri to San Francisco round-trip?

    Currently priced at $278, United Airlines will fly you from Columbia, Missouri to San Francisco and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $362. United Airlines is 40% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Columbia to San Francisco that include hotel bookings?

    Yes. In addition to deals on Columbia to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to San Francisco.

  • Can I find deals for business class flights from Columbia to San Francisco?

    Yes. Cheapflights offers flight deals from Columbia to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to San Francisco?

    Currently, March is the cheapest month in which you can book a flight from Columbia, Missouri to San Francisco (average of $298). Flying from Columbia, Missouri to San Francisco in September is currently the most expensive (average of $791). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
San Bruno
Watsonville
San Ramon
Emeryville
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove

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Top 2 airlines flying from Columbia to San Francisco

Discover the top 2 airlines that operate flights from Columbia to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated 4月 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$278Average$388FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$362Average$539FlexibilityNo cancel feeOn-time71%

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