HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Francisco

$247+ Cheap flights from Columbia, MO to San Francisco (COU - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/29. Fares are subject to change and may not be available on all flights or dates of travel.
COU — SFO
Jul 12 — Jul 191
Sun 7/12
Sun 7/19
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Columbia to San Francisco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Columbia to San Francisco

Cheapest flights from Columbia to San Francisco
Explore the most affordable flight options available from Columbia to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.

This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:26 pm
COU
-
SFO
1 stop7h 17m
American Airlines
Sat 7/115:29 am
SFO
-
COU
1 stop9h 20m
American Airlines
Deal found 6/11$338
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:26 pm
COU
-
SFO
1 stop7h 17m
American Airlines
Sun 7/1911:07 pm
SFO
-
COU
1 stop8h 55m
American Airlines
Deal found 6/9$348
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:26 pm
COU
-
SFO
1 stop7h 17m
American Airlines
Thu 7/166:45 am
SFO
-
COU
1 stop8h 04m
American Airlines
Deal found 6/11$373
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/257:39 pm
COU
-
SFO
1 stop7h 09m
American Airlines
Mon 6/2911:10 pm
SFO
-
COU
1 stop8h 56m
American Airlines
Deal found 6/10$408
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:39 pm
COU
-
SFO
1 stop7h 09m
American Airlines
Sun 6/2812:26 am
SFO
-
COU
1 stop8h 48m
American Airlines
Deal found 6/7$418
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:19 pm
COU
-
SFO
1 stop7h 09m
American Airlines
Sat 7/1111:07 pm
SFO
-
COU
1 stop8h 54m
American Airlines
Deal found 6/11$435
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:00 am
COU
-
SFO
1 stop7h 42m
United Airlines
Tue 11/35:20 am
SFO
-
COU
1 stop7h 09m
United Airlines
Deal found 6/9$438
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1111:45 am
COU
-
SFO
2 stops9h 24m
American Airlines
Thu 7/1612:26 am
SFO
-
COU
1 stop8h 48m
American Airlines
Deal found 6/11$441
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:40 pm
COU
-
SFO
1 stop7h 05m
American Airlines
Thu 9/36:36 am
SFO
-
COU
1 stop8h 11m
American Airlines
Deal found 6/10$447
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:19 pm
COU
-
SFO
1 stop9h 24m
American Airlines
Sat 7/255:29 am
SFO
-
COU
1 stop9h 20m
American Airlines
Deal found 6/8$448

Find flight deals from Columbia to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$338
(American Airlines)

One-way from

$247
(Kiwi.com)

Popular in

September

Cheapest in

March

Average price

$483
Provider with most accurate pricing for Columbia Regional-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbia Regional-San Francisco flights.
Search Deals
From Columbia Regional to San Francisco
Search Deals
One-way flight from Columbia Regional to San Francisco
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Columbia to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Sat 8/29

10:55 am-6:44 pm

1 stop9h 49m

San Francisco

Tue 9/1

11:30 pm-10:16 am

1 stop8h 46m

$438

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Wed 9/23

11:20 am-6:24 pm

1 stop9h 04m

San Francisco

Sun 9/27

10:35 pm-10:37 am

1 stop10h 02m

$448
Quickest round-trip

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Tue 7/7

5:19 pm-10:28 pm

1 stop7h 09m

San Francisco

Sat 7/11

11:07 pm-10:01 am

1 stop8h 54m

$466

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Wed 7/29

10:49 am-6:49 pm

1 stop10h 00m

San Francisco

Tue 8/4

12:50 am-10:13 am

1 stop7h 23m

$473

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Sat 10/31

8:00 am-3:42 pm

1 stop9h 42m

San Francisco

Tue 11/3

8:45 am-12:33 am

2 stops13h 48m

$499

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Mon 7/27

3:25 pm-10:19 am

1 stop20h 54m

San Francisco

Mon 8/3

10:38 pm-10:13 am

1 stop9h 35m

$544

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Sat 7/25

8:00 am-8:02 pm

2 stops14h 02m

San Francisco

Mon 8/3

10:38 pm-10:13 am

1 stop9h 35m

$557
Cheapest one-way

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Fri 7/24

9:56 am-8:45 pm

3 stops36h 49m

$343

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Fri 7/3

9:56 am-4:36 pm

3 stops32h 40m

$350

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Mon 7/6

7:26 pm-12:43 am

1 stop7h 17m

$368

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/8

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

Compare providers for flights from Columbia to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbia to San Francisco in June.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Columbia, Missouri-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbia, Missouri-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbia, Missouri-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Columbia, Missouri-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbia, Missouri-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Columbia to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to San Francisco

How much does it cost to fly round-trip from Columbia, Missouri to San Francisco?

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated June 12, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Columbia to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,810 reviews

Overall

7.4

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Crew

8.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
United Airlines
7.4
Good
9,810 reviews
United Airlines
7.4
Good
9,810 reviews

Overall

7.4

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Crew

8.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
American Airlines
7.1
Good
11,644 reviews
United Airlines
7.4
Good
9,810 reviews

Overall

7.4

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Crew

8.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.

Related info for your journey

Find useful and relevant information for your journey from Columbia to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbia, Missouri to San Francisco?

    American Airlines and United Airlines can get you from Columbia, Missouri to San Francisco in just under 7h 09m. Your travel time can differ by up to 2h 40m. Columbia, Missouri and San Francisco are separated by a distance of 1631 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Columbia, Missouri to San Francisco round-trip?

    Currently priced at $278, United Airlines will fly you from Columbia, Missouri to San Francisco and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $362. United Airlines is 39% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Columbia to San Francisco that include hotel bookings?

    Yes. In addition to deals on Columbia to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to San Francisco.

  • Can I find deals for business class flights from Columbia to San Francisco?

    Yes. Cheapflights offers flight deals from Columbia to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
Roseville
Cupertino
Emeryville
Newark
San Bruno
Watsonville
San Ramon
Vacaville
San Carlos
Redwood City
Daly City
Sunnyvale
Turlock
Vallejo
San Lorenzo

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Columbia to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
St. Louis to Las Vegas flights
Kansas City to Las Vegas flights
Kansas City to Los Angeles flights
St. Louis to Los Angeles flights
St. Louis to San Francisco flights
Kansas City to San Francisco flights
Kansas City to San Diego flights
St. Louis to San Diego flights
Kansas City to Ontario flights
St. Louis to Ontario flights
Kansas City to Sacramento flights
Springfield to Los Angeles flights
St. Louis to San Jose flights
St. Louis to Sacramento flights
Kansas City to Reno flights
Springfield to San Diego flights
Kansas City to Santa Ana flights
St. Louis to Oakland flights
Springfield to Las Vegas flights
Kansas City to San Jose flights
St. Louis to Burbank flights
Kansas City to Oakland flights
St. Louis to Reno flights
St. Louis to Santa Ana flights
Kansas City to Burbank flights
Springfield to Ontario flights
Columbia to Las Vegas flights
St. Louis to Fresno flights
Springfield to Sacramento flights
St. Louis to Long Beach flights
Kansas City to Palm Springs flights
Kansas City to Monterey flights
Kansas City to Long Beach flights
St. Louis to Medford flights
Springfield to Burbank flights
Kansas City to San Luis Obispo flights
Kansas City to Santa Barbara flights
St. Louis to Palm Springs flights
Joplin to Las Vegas flights
Springfield to San Jose flights
Springfield to San Francisco flights
Kansas City to Medford flights
Joplin to Los Angeles flights
St. Louis to Santa Barbara flights
Kansas City to Fresno flights
Columbia to Los Angeles flights
Joplin to San Francisco flights
Springfield to Bakersfield flights
Springfield to Santa Ana flights

Top 2 airlines flying from Columbia to San Francisco

Discover the top 2 airlines that operate flights from Columbia to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$278Average$388FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$362Average$510FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.