$318+ Cheap flights from San Francisco to Columbia, MO (SFO - COU)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — COU
Sep 10 — Sep 171
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Columbia with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Columbia
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Cheapest flights from San Francisco to ColumbiaExplore the most affordable flight options available from San Francisco to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2026.
Explore the most affordable flight options available from San Francisco to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2026.
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:38 pm -
1 stop7h 50m
Sat 9/511:46 am -
1 stop8h 03m
Deal found 8/10![American Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:46 pm -
1 stop9h 10m
Wed 9/3011:59 am -
1 stop9h 18m
Deal found 8/8![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:55 pm -
1 stop7h 00m
Sat 9/510:55 am -
1 stop8h 28m
Deal found 8/8![United Airlines logo]()
$371
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:36 am -
1 stop8h 11m
Fri 9/113:31 pm -
1 stop10h 25m
Deal found 8/7![American Airlines logo]()
$383
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:35 am -
1 stop8h 04m
Tue 10/611:15 am -
1 stop10h 17m
Deal found 8/9![United Airlines logo]()
$448
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:30 am -
1 stop9h 17m
Sat 8/2211:46 am -
1 stop9h 27m
Deal found 8/7![American Airlines logo]()
$456
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:46 pm -
1 stop9h 10m
Sun 9/276:26 pm -
1 stop7h 02m
Deal found 8/7![American Airlines logo]()
$457
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:36 am -
1 stop8h 11m
Sat 8/1512:58 pm -
1 stop7h 02m
Deal found 8/5![American Airlines logo]()
$501
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:30 pm -
1 stop9h 09m
Mon 10/263:00 pm -
2 stops19h 05m
Deal found 8/10![United Airlines logo]()
$520
Best flights from San Francisco to ColumbiaDiscover carefully curated flight deals from San Francisco to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 11, 2026.
Discover carefully curated flight deals from San Francisco to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 11, 2026.
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:58 am -
1 stop8h 21m
Sat 9/56:00 am -
1 stop7h 26m
Deal found 8/7![American Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:35 am -
1 stop8h 04m
Tue 10/611:15 am -
1 stop10h 17m
Deal found 8/9![United Airlines logo]()
$448
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:30 am -
1 stop9h 17m
Sat 8/2211:46 am -
1 stop9h 27m
Deal found 8/9![American Airlines logo]()
$501
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:30 pm -
1 stop9h 09m
Mon 10/263:00 pm -
2 stops19h 05m
Deal found 8/10![United Airlines logo]()
$520
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:36 am -
1 stop8h 11m
Sat 8/1512:58 pm -
1 stop7h 02m
Deal found 8/5![American Airlines logo]()
$501
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:00 am -
2 stops13h 55m
Fri 9/1111:17 am -
1 stop9h 07m
Deal found 8/8![United Airlines logo]()
$582
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/49:09 am -
2 stops11h 19m
Fri 9/114:51 pm -
1 stop8h 37m
Deal found 8/6![American Airlines logo]()
$540
Last-minute flights from San Francisco to ColumbiaDiscover last-minute flight deals from San Francisco to Columbia. Data last updated August 11, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Columbia. Data last updated August 11, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:30 am -
1 stop9h 17m
Sat 8/2211:46 am -
1 stop9h 27m
Deal found 8/7![American Airlines logo]()
$456
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:38 pm -
1 stop7h 50m
Sat 9/511:46 am -
1 stop8h 03m
Deal found 8/10![American Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:55 pm -
1 stop7h 00m
Sat 9/510:55 am -
1 stop8h 28m
Deal found 8/8![United Airlines logo]()
$371
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:36 am -
1 stop8h 11m
Fri 9/113:31 pm -
1 stop10h 25m
Deal found 8/7![American Airlines logo]()
$383
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:46 pm -
1 stop9h 10m
Wed 9/3011:59 am -
1 stop9h 18m
Deal found 8/8![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:46 pm -
1 stop9h 10m
Sun 9/276:26 pm -
1 stop7h 02m
Deal found 8/7![American Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:35 am -
1 stop8h 04m
Tue 10/611:15 am -
1 stop10h 17m
Deal found 8/9![United Airlines logo]()
$448
One-way flights from San Francisco to ColumbiaSearch for one-way flight options from San Francisco to Columbia. Find affordable one-way fares based on user searches. Data last updated August 11, 2026.
Search for one-way flight options from San Francisco to Columbia. Find affordable one-way fares based on user searches. Data last updated August 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
2 stops35h 43m
Deal found 8/9![Multiple Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:10 am -
1 stop8h 44m
Deal found 8/9![American Airlines logo]()
$373
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:00 am -
1 stop7h 30m
Deal found 8/7![United Airlines logo]()
$463
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/110:42 pm -
2 stops19h 59m
Deal found 8/6![United Airlines logo]()
$473
This KAYAK deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:33 am -
2 stops10h 30m
Deal found 8/7![American Airlines logo]()
$479
Find flight deals from San Francisco to Columbia
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Columbia (COU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 11, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $348 (American Airlines) |
One-way from | $318 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2026.
Use the filters below to find and compare flights from San Francisco to Columbia that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoColumbia
SFO San Francisco - COU Columbia Regional
SFOCOU
San Francisco
Tue 9/1
10:58 am-9:19 pm
1 stop8h 21m
Columbia Regional
Sat 9/5
6:00 am-11:26 am
1 stop7h 26m
$348
San FranciscoColumbia
SFO San Francisco - COU Columbia Regional
SFOCOU
San Francisco
Mon 9/28
12:35 am-10:39 am
1 stop8h 04m
Columbia Regional
Tue 10/6
11:15 am-7:32 pm
1 stop10h 17m
$448
San FranciscoColumbia
SFO San Francisco - COU Columbia Regional
SFOCOU
San Francisco
Wed 8/19
5:30 am-4:47 pm
1 stop9h 17m
Columbia Regional
Sat 8/22
11:46 am-7:13 pm
1 stop9h 27m
$501
Quickest round-trip
San FranciscoColumbia
SFO San Francisco - COU Columbia Regional
SFOCOU
San Francisco
Thu 8/13
6:36 am-4:47 pm
1 stop8h 11m
Columbia Regional
Sat 8/15
12:58 pm-6:00 pm
1 stop7h 02m
$501
San FranciscoColumbia
SFO San Francisco - COU Columbia Regional
SFOCOU
San Francisco
Fri 10/23
11:30 pm-10:39 am
1 stop9h 09m
Columbia Regional
Mon 10/26
3:00 pm-8:05 am
2 stops19h 05m
$520
San FranciscoColumbia
SFO San Francisco - COU Columbia Regional
SFOCOU
San Francisco
Fri 9/4
9:09 am-10:28 pm
2 stops11h 19m
Columbia Regional
Fri 9/11
4:51 pm-11:28 pm
1 stop8h 37m
$540
San FranciscoColumbia
SFO San Francisco - COU Columbia Regional
SFOCOU
San Francisco
Fri 9/4
7:00 am-10:55 pm
2 stops13h 55m
Columbia Regional
Fri 9/11
11:17 am-6:24 pm
1 stop9h 07m
$582
Cheapest one-way
San FranciscoColumbia
SFO San Francisco - COU Columbia Regional
SFOCOU
San Francisco
Thu 10/8
6:00 am-7:43 pm
2 stops35h 43m
$318
San FranciscoColumbia
SFO San Francisco - COU Columbia Regional
SFOCOU
San Francisco
Thu 10/8
7:10 am-5:54 pm
1 stop8h 44m
$373
Quickest one-way
San FranciscoColumbia
SFO San Francisco - COU Columbia Regional
SFOCOU
San Francisco
Sun 11/1
5:00 am-2:18 pm
1 stop7h 18m
$373
Showing 1-10 of 11 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on San Francisco-Columbia, Missouri flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on San Francisco-Columbia, Missouri flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from San Francisco-Columbia, Missouri flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Columbia, Missouri flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Columbia, Missouri flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Columbia
Have a flexible travel schedule? Discover the best time to fly to Columbia from San Francisco with our price prediction graph.
SFO-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Columbia
Get insights into the airlines that provide service to Columbia. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbia. Reviews last updated August 11, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from San Francisco to Columbia to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Food
6.7
Crew
8.1
Comfort
7.3
Entertainment
7.1
Overall
7.4
Reviews
1 / 20
10.0
ExcellentAnonymous,Feb 2024
SFO - EWR
Boarding
7.7
Food
6.7
Crew
8.1
Comfort
7.3
Entertainment
7.1
Overall
7.4
Reviews
1 / 20
10.0
ExcellentAnonymous,Feb 2024
SFO - EWR
Boarding
7.7
Food
6.7
Crew
8.1
Comfort
7.3
Entertainment
7.1
Overall
7.4
Reviews
1 / 20
10.0
ExcellentAnonymous,Feb 2024
SFO - EWR
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Columbia?
Book flights to Columbia if you plan to visit one of these locationsJefferson City
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Other flights to Columbia
Explore flights to Columbia departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 11, 2026.
Complete your trip
Complete your trip to Columbia by adding a car rental and/or hotel reservation to your travel itinerary.
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San Francisco and Columbia flights
Browse other San Francisco and Columbia flight options. Last updated on August 11, 2026.
Other flights from San Francisco
Browse through other flights departing from San Francisco. Flights are based on user searches made on Cheapflights and were last updated on August 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from San Francisco to Columbia
Discover the top 2 airlines that operate flights from San Francisco to Columbia. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$278 | Average$485 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$297 | Average$469 | FlexibilityNo cancel fee | On-time71% |