$155+ Cheap flights from Medford to St. Louis (MFR - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Aug 16 — Aug 231
Round-trip
1 adult, Economy
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Find cheap flights from Medford to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Medford to St. Louis
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Cheapest flights from Medford to St. LouisExplore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 17, 2026.
Explore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 17, 2026.
This Alaska Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/241:23 pm
MFR
- STL
1 stop8h 36m
Alaska Airlines
Tue 10/277:00 am
STL
- MFR
1 stop7h 46m
Alaska Airlines
Deal found 7/15![Alaska Airlines logo]()
$425
This Alaska Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:35 pm
MFR
- STL
1 stop19h 35m
Alaska Airlines
Sun 8/237:36 pm
STL
- MFR
1 stop16h 15m
Alaska Airlines
Deal found 7/12![Alaska Airlines logo]()
$442
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:00 am
MFR
- STL
1 stop5h 40m
United Airlines
Wed 8/197:25 am
STL
- MFR
2 stops12h 33m
United Airlines
Deal found 7/13![United Airlines logo]()
$447
This Alaska Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:28 am
MFR
- STL
1 stop6h 10m
Alaska Airlines
Sat 8/296:08 pm
STL
- MFR
1 stop6h 41m
Alaska Airlines
Deal found 7/12![Alaska Airlines logo]()
$459
This United Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:08 pm
MFR
- STL
1 stop5h 30m
United Airlines
Sun 9/135:10 am
STL
- MFR
2 stops8h 52m
United Airlines
Deal found 7/14![United Airlines logo]()
$464
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
MFR
- STL
2 stops12h 46m
United Airlines
Fri 8/214:40 pm
STL
- MFR
1 stop6h 28m
United Airlines
Deal found 7/12![United Airlines logo]()
$472
This Booking.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:00 am
MFR
- STL
2 stops32h 10m
Alaska Airlines
Fri 8/216:08 pm
STL
- MFR
1 stop6h 41m
Alaska Airlines
Deal found 7/15![Alaska Airlines logo]()
$506
This Alaska Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:58 am
MFR
- STL
1 stop10h 59m
Alaska Airlines
Tue 8/47:56 pm
STL
- MFR
1 stop15h 55m
Alaska Airlines
Deal found 7/13![Alaska Airlines logo]()
$509
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:11 pm
MFR
- STL
2 stops7h 46m
United Airlines
Thu 7/301:13 pm
STL
- MFR
2 stops11h 46m
United Airlines
Deal found 7/16![United Airlines logo]()
$510
Best flights from Medford to St. LouisDiscover carefully curated flight deals from Medford to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 17, 2026.
Discover carefully curated flight deals from Medford to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 17, 2026.
This Alaska Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:52 pm
MFR
- STL
1 stop23h 18m
Alaska Airlines
Sun 8/237:36 pm
STL
- MFR
1 stop16h 15m
Alaska Airlines
Deal found 7/13![Alaska Airlines logo]()
$442
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
MFR
- STL
2 stops12h 46m
United Airlines
Fri 8/214:40 pm
STL
- MFR
1 stop6h 28m
United Airlines
Deal found 7/12![United Airlines logo]()
$472
This Alaska Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:28 am
MFR
- STL
1 stop6h 10m
Alaska Airlines
Sat 8/296:08 pm
STL
- MFR
1 stop6h 41m
Alaska Airlines
Deal found 7/14![Alaska Airlines logo]()
$442
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:11 pm
MFR
- STL
2 stops7h 46m
United Airlines
Thu 7/301:13 pm
STL
- MFR
2 stops11h 46m
United Airlines
Deal found 7/16![United Airlines logo]()
$510
This Alaska Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/241:23 pm
MFR
- STL
1 stop8h 36m
Alaska Airlines
Tue 10/277:00 am
STL
- MFR
2 stops17h 48m
Alaska Airlines
Deal found 7/15![Alaska Airlines logo]()
$484
This Alaska Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:35 pm
MFR
- STL
1 stop19h 02m
Alaska Airlines
Tue 8/45:37 pm
STL
- MFR
1 stop7h 29m
Alaska Airlines
Deal found 7/11![Alaska Airlines logo]()
$509
Last-minute flights from Medford to St. LouisDiscover last-minute flight deals from Medford to St. Louis. Data last updated July 17, 2026 and is based on user searches.
Discover last-minute flight deals from Medford to St. Louis. Data last updated July 17, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:11 pm
MFR
- STL
2 stops7h 46m
United Airlines
Thu 7/301:13 pm
STL
- MFR
2 stops11h 46m
United Airlines
Deal found 7/16![United Airlines logo]()
$510
This Alaska Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:58 am
MFR
- STL
1 stop10h 59m
Alaska Airlines
Tue 8/47:56 pm
STL
- MFR
1 stop15h 55m
Alaska Airlines
Deal found 7/13![Alaska Airlines logo]()
$509
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:00 am
MFR
- STL
1 stop5h 40m
United Airlines
Wed 8/197:25 am
STL
- MFR
2 stops12h 33m
United Airlines
Deal found 7/13![United Airlines logo]()
$447
This Alaska Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:35 pm
MFR
- STL
1 stop19h 35m
Alaska Airlines
Sun 8/237:36 pm
STL
- MFR
1 stop16h 15m
Alaska Airlines
Deal found 7/12![Alaska Airlines logo]()
$442
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
MFR
- STL
2 stops12h 46m
United Airlines
Fri 8/214:40 pm
STL
- MFR
1 stop6h 28m
United Airlines
Deal found 7/12![United Airlines logo]()
$472
This Booking.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:00 am
MFR
- STL
2 stops32h 10m
Alaska Airlines
Fri 8/216:08 pm
STL
- MFR
1 stop6h 41m
Alaska Airlines
Deal found 7/15![Alaska Airlines logo]()
$506
This Alaska Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:28 am
MFR
- STL
1 stop6h 10m
Alaska Airlines
Sat 8/296:08 pm
STL
- MFR
1 stop6h 41m
Alaska Airlines
Deal found 7/12![Alaska Airlines logo]()
$459
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:00 am
MFR
- STL
2 stops10h 46m
United Airlines
Sat 8/294:40 pm
STL
- MFR
1 stop6h 29m
United Airlines
Deal found 7/12![United Airlines logo]()
$530
One-way flights from Medford to St. LouisSearch for one-way flight options from Medford to St. Louis. Find affordable one-way fares based on user searches. Data last updated July 17, 2026.
Search for one-way flight options from Medford to St. Louis. Find affordable one-way fares based on user searches. Data last updated July 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:17 pm
MFR
- STL
2 stops20h 06m
Multiple Airlines
Deal found 7/16![Multiple Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:57 pm
MFR
- STL
3 stops34h 43m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$189
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:01 pm
MFR
- STL
1 stop5h 35m
United Airlines
Deal found 7/15![United Airlines logo]()
$213
This Alaska Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/141:27 pm
MFR
- STL
1 stop8h 32m
Alaska Airlines
Deal found 7/16![Alaska Airlines logo]()
$230
This Expedia deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/410:33 am
MFR
- STL
1 stop11h 26m
Alaska Airlines
Deal found 7/12![Alaska Airlines logo]()
$235
This Expedia deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2810:31 am
MFR
- STL
1 stop6h 26m
Alaska Airlines
Deal found 7/13![Alaska Airlines logo]()
$250
Find flight deals from Medford to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $425 (Alaska Airlines) |
One-way from | $155 (Kiwi.com) |
Popular in | December |
Cheapest in | August |
Average price | $616 |
Cheapflights Fare Finder
Customize your flight search to find flights from Medford to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 17, 2026.
Use the filters below to find and compare flights from Medford to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Tue 8/18
3:52 pm-5:10 pm
1 stop23h 18m
Lambert-St Louis
Sun 8/23
7:36 pm-9:51 am
1 stop16h 15m
$442
Quickest round-trip
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Tue 8/25
10:28 am-6:38 pm
1 stop6h 10m
Lambert-St Louis
Sat 8/29
6:08 pm-10:49 pm
1 stop6h 41m
$442
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Wed 8/19
6:00 am-8:46 pm
2 stops12h 46m
Lambert-St Louis
Fri 8/21
4:40 pm-9:08 pm
1 stop6h 28m
$472
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Sat 10/24
1:23 pm-11:59 pm
1 stop8h 36m
Lambert-St Louis
Tue 10/27
7:00 am-10:48 pm
2 stops17h 48m
$484
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Fri 7/31
7:35 pm-4:37 pm
1 stop19h 02m
Lambert-St Louis
Tue 8/4
5:37 pm-11:06 pm
1 stop7h 29m
$509
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Wed 7/29
2:11 pm-11:57 pm
2 stops7h 46m
Lambert-St Louis
Thu 7/30
1:13 pm-10:59 pm
2 stops11h 46m
$510
Cheapest one-way
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Sun 10/4
8:57 pm-9:40 am
3 stops34h 43m
$189
Quickest one-way
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Sat 10/3
1:01 pm-8:36 pm
1 stop5h 35m
$213
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Fri 8/14
1:27 pm-11:59 pm
1 stop8h 32m
$230
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Tue 7/28
10:31 am-6:57 pm
1 stop6h 26m
$250
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Medford to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to St. Louis in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Medford-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Medford-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Medford to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Medford with our price prediction graph.
MFR-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated July 17, 2026.
Peruse reviews from past customers who have flown with Delta and United Airlines from Medford to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Overall
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodAnonymous,Jul 2023
DTW - STL
Comfort
7.8
Overall
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodAnonymous,Jul 2023
DTW - STL
Comfort
7.8
Overall
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodAnonymous,Jul 2023
DTW - STL
Related info for your journey
Find useful and relevant information for your journey from Medford to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Alton
Farmington
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Medford and St. Louis flights
Browse other Medford and St. Louis flight options. Last updated on July 17, 2026.
Other flights from Medford
Browse through other flights departing from Medford. Flights are based on user searches made on Cheapflights and were last updated on July 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 17, 2026.
Top 2 airlines flying from Medford to St. Louis
Discover the top 2 airlines that operate flights from Medford to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$178 | Average$364 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$224 | Average$513 | FlexibilityNo cancel fee | On-time69% |