$200+ Cheap flights from Medford to St. Louis (MFR - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/16. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Nov 25 — Dec 21
Round-trip
1 adult, Economy
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Find cheap flights from Medford to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Medford to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Medford to St. LouisExplore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
Explore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/810:58 am -
1 stop23h 35m
Thu 11/1212:14 pm -
2 stops34h 47m
Deal found 10/24![Multiple Airlines logo]()
$394
This Alaska Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:11 am -
1 stop11h 48m
Mon 11/236:00 am -
1 stop10h 15m
Deal found 10/22![Alaska Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:00 am -
1 stop5h 53m
Sun 12/138:40 am -
2 stops13h 35m
Deal found 10/23![United Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:34 pm -
2 stops7h 48m
Wed 12/166:03 am -
2 stops12h 38m
Deal found 10/26![Delta logo]()
$409
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:15 am -
1 stop6h 15m
Fri 11/276:13 am -
2 stops8h 38m
Deal found 10/23![Delta logo]()
$424
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/191:34 pm -
2 stops7h 48m
Mon 11/236:13 am -
2 stops8h 38m
Deal found 10/23![Delta logo]()
$429
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:15 am -
1 stop6h 15m
Sun 11/157:00 pm -
1 stop6h 55m
Deal found 10/26![Delta logo]()
$434
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:00 pm -
1 stop5h 59m
Mon 11/94:39 pm -
1 stop6h 39m
Deal found 10/21![United Airlines logo]()
$464
This Alaska Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:20 pm -
1 stop8h 39m
Thu 11/126:00 am -
1 stop10h 36m
Deal found 10/24![Alaska Airlines logo]()
$469
Best flights from Medford to St. LouisDiscover carefully curated flight deals from Medford to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
Discover carefully curated flight deals from Medford to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
This Alaska Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:11 am -
1 stop11h 48m
Sun 11/156:00 am -
1 stop10h 36m
Deal found 10/22![Alaska Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:30 am -
1 stop8h 41m
Sun 12/132:50 pm -
1 stop8h 36m
Deal found 10/23![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2212:25 pm -
2 stops8h 53m
Fri 2/262:15 pm -
2 stops10h 57m
Deal found 10/26![Delta logo]()
$409
This Alaska Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:46 pm -
1 stop17h 36m
Mon 11/236:00 am -
1 stop10h 15m
Deal found 10/25![Alaska Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:34 pm -
2 stops7h 48m
Wed 12/166:03 am -
2 stops12h 38m
Deal found 10/26![Delta logo]()
$409
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:15 am -
1 stop6h 15m
Fri 11/276:13 am -
2 stops8h 38m
Deal found 10/22![Delta logo]()
$424
Last-minute flights from Medford to St. LouisDiscover last-minute flight deals from Medford to St. Louis. Data last updated October 26, 2026 and is based on user searches.
Discover last-minute flight deals from Medford to St. Louis. Data last updated October 26, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:00 pm -
1 stop5h 59m
Mon 11/94:39 pm -
1 stop6h 39m
Deal found 10/21![United Airlines logo]()
$464
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/810:58 am -
1 stop23h 35m
Thu 11/1212:14 pm -
2 stops34h 47m
Deal found 10/24![Multiple Airlines logo]()
$394
This Alaska Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:20 pm -
1 stop8h 39m
Thu 11/126:00 am -
1 stop10h 36m
Deal found 10/24![Alaska Airlines logo]()
$469
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:15 am -
1 stop6h 15m
Sun 11/157:00 pm -
1 stop6h 55m
Deal found 10/26![Delta logo]()
$434
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:34 pm -
1 stop5h 44m
Wed 12/166:03 am -
2 stops8h 48m
Deal found 10/26![Delta logo]()
$404
This Alaska Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:11 am -
1 stop11h 48m
Mon 11/236:00 am -
1 stop10h 15m
Deal found 10/22![Alaska Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/191:34 pm -
2 stops7h 48m
Mon 11/236:13 am -
2 stops8h 38m
Deal found 10/23![Delta logo]()
$429
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:15 am -
1 stop6h 15m
Fri 11/276:13 am -
2 stops8h 38m
Deal found 10/23![Delta logo]()
$424
One-way flights from Medford to St. LouisSearch for one-way flight options from Medford to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
Search for one-way flight options from Medford to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/161:31 pm -
1 stop5h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Delta logo]()
$200
This Priceline deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:08 am -
1 stop7h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Alaska Airlines logo]()
$255
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:01 am -
2 stops8h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![United Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1710:51 am -
3 stops26h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/165:55 pm -
3 stops27h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$610
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:06 am -
3 stops30h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$625
Find flight deals from Medford to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $394 (Kiwi.com) |
One-way from | $200 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Medford to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
Use the filters below to find and compare flights from Medford to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MedfordSt. Louis
MFR Medford - STL Lambert-St Louis
MFRSTL
Medford
Wed 12/16
6:10 am-9:28 pm
2 stops13h 18m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$205
Quickest round-trip
MedfordSt. Louis
MFR Medford - STL Lambert-St Louis
MFRSTL
Medford
Thu 11/26
5:08 am-2:22 pm
1 stop7h 14m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$255
MedfordSt. Louis
MFR Medford - STL Lambert-St Louis
MFRSTL
Medford
Thu 12/17
7:20 pm-10:42 am
2 stops13h 22m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$260
MedfordSt. Louis
MFR Medford - STL Lambert-St Louis
MFRSTL
Medford
Thu 11/26
5:01 am-3:43 pm
2 stops8h 42m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$260
MedfordSt. Louis
MFR Medford - STL Lambert-St Louis
MFRSTL
Medford
Thu 11/12
10:11 am-11:59 pm
1 stop11h 48m
Lambert-St Louis
Sun 11/15
6:00 am-2:36 pm
1 stop10h 36m
$399
MedfordSt. Louis
MFR Medford - STL Lambert-St Louis
MFRSTL
Medford
Thu 12/10
7:30 am-6:11 pm
1 stop8h 41m
Lambert-St Louis
Sun 12/13
2:50 pm-9:26 pm
1 stop8h 36m
$399
MedfordSt. Louis
MFR Medford - STL Lambert-St Louis
MFRSTL
Medford
Thu 11/19
6:46 pm-2:22 pm
1 stop17h 36m
Lambert-St Louis
Mon 11/23
6:00 am-2:15 pm
1 stop10h 15m
$399
MedfordSt. Louis
MFR Medford - STL Lambert-St Louis
MFRSTL
Medford
Mon 2/22
12:25 pm-11:18 pm
2 stops8h 53m
Lambert-St Louis
Fri 2/26
2:15 pm-11:12 pm
2 stops10h 57m
$409
MedfordSt. Louis
MFR Medford - STL Lambert-St Louis
MFRSTL
Medford
Wed 11/18
1:34 pm-11:22 pm
2 stops7h 48m
Lambert-St Louis
Wed 12/16
6:03 am-4:41 pm
2 stops12h 38m
$409
MedfordSt. Louis
MFR Medford - STL Lambert-St Louis
MFRSTL
Medford
Mon 11/23
5:15 am-1:30 pm
1 stop6h 15m
Lambert-St Louis
Fri 11/27
6:13 am-12:51 pm
2 stops8h 38m
$424
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Medford to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to St. Louis in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Medford-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Medford-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Medford to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Medford with our price prediction graph.
MFR-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated October 26, 2026.
Peruse reviews from past customers who have flown with Delta and United Airlines from Medford to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Medford to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Maryland Heights
Chesterfield
Collinsville
Edwardsville
Glencoe
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Medford and St. Louis flights
Browse other Medford and St. Louis flight options. Last updated on October 26, 2026.
Other flights from Medford
Browse through other flights departing from Medford. Flights are based on user searches made on Cheapflights and were last updated on October 26, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 26, 2026.
Top 2 airlines flying from Medford to St. Louis
Discover the top 2 airlines that operate flights from Medford to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$204 | Average$404 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$224 | Average$513 | FlexibilityNo cancel fee | On-time69% |