$359+ Cheap flights from Medford to St. Louis (MFR - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Jul 12 — Jul 191
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Medford to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Medford to St. Louis
Cheapest
Best
Last-minute
Cheapest flights from Medford to St. LouisExplore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
Explore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/41:23 pm
MFR
- STL
1 stop8h 35m
American Airlines
Tue 8/188:00 am
STL
- MFR
1 stop6h 47m
American Airlines
Deal found 6/8![American Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:15 am
MFR
- STL
2 stops10h 40m
Delta
Sun 8/237:45 pm
STL
- MFR
1 stop6h 10m
Delta
Deal found 6/7![Delta logo]()
$364
This Alaska Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:52 pm
MFR
- STL
1 stop23h 18m
Alaska Airlines
Sun 8/237:36 pm
STL
- MFR
1 stop16h 15m
Alaska Airlines
Deal found 6/9![Alaska Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/111:23 pm
MFR
- STL
1 stop8h 35m
American Airlines
Tue 7/148:01 am
STL
- MFR
1 stop6h 49m
American Airlines
Deal found 6/11![American Airlines logo]()
$425
This Alaska Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
MFR
- STL
1 stop6h 06m
Alaska Airlines
Tue 9/16:35 am
STL
- MFR
1 stop8h 15m
Alaska Airlines
Deal found 6/7![Alaska Airlines logo]()
$429
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/281:23 pm
MFR
- STL
1 stop8h 35m
American Airlines
Tue 8/48:01 am
STL
- MFR
1 stop6h 49m
American Airlines
Deal found 6/11![American Airlines logo]()
$430
Best flights from Medford to St. LouisDiscover carefully curated flight deals from Medford to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
Discover carefully curated flight deals from Medford to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
This Alaska Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:23 pm
MFR
- STL
1 stop8h 36m
Alaska Airlines
Sat 10/316:00 am
STL
- MFR
1 stop8h 46m
Alaska Airlines
Deal found 6/11![Alaska Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:15 am
MFR
- STL
2 stops10h 40m
Delta
Sun 8/237:45 pm
STL
- MFR
1 stop6h 10m
Delta
Deal found 6/10![Delta logo]()
$364
This Alaska Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:52 pm
MFR
- STL
1 stop23h 18m
Alaska Airlines
Sun 8/237:36 pm
STL
- MFR
1 stop16h 15m
Alaska Airlines
Deal found 6/7![Alaska Airlines logo]()
$379
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:15 am
MFR
- STL
2 stops10h 40m
Delta
Tue 8/183:50 pm
STL
- MFR
2 stops10h 05m
Delta
Deal found 6/8![Delta logo]()
$449
This Alaska Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:15 am
MFR
- STL
1 stop9h 22m
Alaska Airlines
Tue 8/47:56 pm
STL
- MFR
1 stop15h 55m
Alaska Airlines
Deal found 6/7![Alaska Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:20 am
MFR
- STL
1 stop6h 16m
Delta
Mon 6/296:21 am
STL
- MFR
2 stops12h 23m
Delta
Deal found 6/9![Delta logo]()
$464
This Orbitz deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/283:52 pm
MFR
- STL
1 stop22h 45m
Alaska Airlines
Tue 8/47:56 pm
STL
- MFR
1 stop15h 55m
Alaska Airlines
Deal found 6/11![Alaska Airlines logo]()
$429
This Alaska Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
MFR
- STL
1 stop6h 06m
Alaska Airlines
Tue 9/16:35 am
STL
- MFR
1 stop8h 15m
Alaska Airlines
Deal found 6/10![Alaska Airlines logo]()
$429
Last-minute flights from Medford to St. LouisDiscover last-minute flight deals from Medford to St. Louis. Data last updated June 12, 2026 and is based on user searches.
Discover last-minute flight deals from Medford to St. Louis. Data last updated June 12, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:00 am
MFR
- STL
1 stop5h 42m
United Airlines
Wed 6/1710:25 am
STL
- MFR
2 stops9h 26m
United Airlines
Deal found 6/11![United Airlines logo]()
$480
This Booking.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:35 pm
MFR
- STL
1 stop19h 02m
Alaska Airlines
Tue 7/77:56 pm
STL
- MFR
1 stop15h 58m
Alaska Airlines
Deal found 6/9![Alaska Airlines logo]()
$449
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1112:20 pm
MFR
- STL
2 stops7h 43m
Delta
Tue 7/147:55 pm
STL
- MFR
1 stop5h 59m
Delta
Deal found 6/11![Delta logo]()
$364
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/111:23 pm
MFR
- STL
1 stop8h 35m
American Airlines
Tue 7/148:01 am
STL
- MFR
1 stop6h 49m
American Airlines
Deal found 6/11![American Airlines logo]()
$425
This Orbitz deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/283:52 pm
MFR
- STL
1 stop22h 45m
Alaska Airlines
Tue 8/47:56 pm
STL
- MFR
1 stop15h 55m
Alaska Airlines
Deal found 6/11![Alaska Airlines logo]()
$429
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/281:23 pm
MFR
- STL
1 stop8h 35m
American Airlines
Tue 8/48:01 am
STL
- MFR
1 stop6h 49m
American Airlines
Deal found 6/11![American Airlines logo]()
$430
This Alaska Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:35 pm
MFR
- STL
2 stops10h 56m
Alaska Airlines
Tue 8/47:56 pm
STL
- MFR
1 stop15h 55m
Alaska Airlines
Deal found 6/8![Alaska Airlines logo]()
$464
Find flight deals from Medford to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $359 (American Airlines) |
Popular in | December |
Cheapest in | August |
Average price | $299 |
Cheapflights Fare Finder
Customize your flight search to find flights from Medford to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Medford to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Wed 10/28
1:23 pm-11:59 pm
1 stop8h 36m
Lambert-St Louis
Sat 10/31
6:00 am-12:46 pm
1 stop8h 46m
$359
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Tue 8/18
6:15 am-6:55 pm
2 stops10h 40m
Lambert-St Louis
Sun 8/23
7:45 pm-11:55 pm
1 stop6h 10m
$364
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Tue 8/18
3:52 pm-5:10 pm
1 stop23h 18m
Lambert-St Louis
Sun 8/23
7:36 pm-9:51 am
1 stop16h 15m
$379
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Fri 7/31
5:15 am-4:37 pm
1 stop9h 22m
Lambert-St Louis
Tue 8/4
7:56 pm-9:51 am
1 stop15h 55m
$429
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Tue 7/28
3:52 pm-4:37 pm
1 stop22h 45m
Lambert-St Louis
Tue 8/4
7:56 pm-9:51 am
1 stop15h 55m
$429
Quickest round-trip
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Sat 8/29
6:00 am-2:06 pm
1 stop6h 06m
Lambert-St Louis
Tue 9/1
6:35 am-12:50 pm
1 stop8h 15m
$429
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Tue 8/4
6:15 am-6:55 pm
2 stops10h 40m
Lambert-St Louis
Tue 8/18
3:50 pm-11:55 pm
2 stops10h 05m
$449
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Thu 6/25
5:20 am-1:36 pm
1 stop6h 16m
Lambert-St Louis
Mon 6/29
6:21 am-4:44 pm
2 stops12h 23m
$464
Sorted by cheapest first
Compare providers for flights from Medford to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to St. Louis in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Medford-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Medford-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Medford to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Medford with our price prediction graph.
MFR-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Medford to St. Louis
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated June 12, 2026.
Peruse reviews from past customers who have flown with Delta and United Airlines from Medford to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
7.9
Crew
8.5
Entertainment
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Overall
7.9
Crew
8.5
Entertainment
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Overall
7.9
Crew
8.5
Entertainment
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Medford to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Medford
Popular flights
St. Louis flight routes
Alternative routes for Medford to St. Louis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Medford to St. Louis by cabin class
Find flights from Medford to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Medford and St. Louis flights
Browse other Medford and St. Louis flight options. Last updated on June 12, 2026.
Other flights from Medford
Browse through other flights departing from Medford. Flights are based on user searches made on Cheapflights and were last updated on June 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 12, 2026.
Top 2 airlines flying from Medford to St. Louis
Discover the top 2 airlines that operate flights from Medford to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$192 | Average$364 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$224 | Average$540 | FlexibilityNo cancel fee | On-time69% |