$278+ Cheap flights from Medford to St. Louis (MFR - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Aug 27 — Sep 31
Round-trip
1 adult, Economy
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Find cheap flights from Medford to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Medford to St. Louis
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Best
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One-way
Cheapest flights from Medford to St. LouisExplore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
Explore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
This Expedia deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:23 pm
MFR
- STL
1 stop8h 36m
Alaska Airlines
Sat 10/246:02 am
STL
- MFR
2 stops16h 35m
Alaska Airlines
Deal found 7/26![Alaska Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:15 am
MFR
- STL
1 stop6h 17m
Delta
Sat 10/245:00 pm
STL
- MFR
1 stop6h 59m
Delta
Deal found 7/26![Delta logo]()
$435
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:00 am
MFR
- STL
2 stops12h 36m
United Airlines
Tue 10/274:39 pm
STL
- MFR
1 stop6h 39m
United Airlines
Deal found 7/26![United Airlines logo]()
$436
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:17 am
MFR
- STL
2 stops12h 31m
American Airlines
Sat 10/245:40 am
STL
- MFR
2 stops9h 12m
American Airlines
Deal found 7/26![American Airlines logo]()
$445
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:00 am
MFR
- STL
1 stop5h 40m
United Airlines
Sun 9/204:40 pm
STL
- MFR
1 stop6h 28m
United Airlines
Deal found 7/24![United Airlines logo]()
$452
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/11:28 pm
MFR
- STL
1 stop8h 21m
American Airlines
Fri 12/45:14 am
STL
- MFR
2 stops10h 15m
American Airlines
Deal found 7/26![American Airlines logo]()
$457
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:40 pm
MFR
- STL
1 stop6h 37m
Multiple Airlines
Sun 10/2510:35 am
STL
- MFR
2 stops29h 39m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$459
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
- STL
2 stops19h 45m
Multiple Airlines
Thu 8/137:10 pm
STL
- MFR
1 stop21h 38m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$462
This Priceline deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
MFR
- STL
1 stop6h 06m
Alaska Airlines
Sat 8/296:35 am
STL
- MFR
1 stop8h 15m
Alaska Airlines
Deal found 7/25![Alaska Airlines logo]()
$469
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:27 pm
MFR
- STL
2 stops9h 00m
American Airlines
Sun 9/208:00 am
STL
- MFR
1 stop6h 57m
American Airlines
Deal found 7/24![American Airlines logo]()
$477
This Expedia deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:15 am
MFR
- STL
1 stop9h 22m
Alaska Airlines
Thu 8/132:50 pm
STL
- MFR
1 stop11h 14m
Alaska Airlines
Deal found 7/23![Alaska Airlines logo]()
$490
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/52:11 pm
MFR
- STL
2 stops7h 46m
United Airlines
Thu 8/139:00 am
STL
- MFR
1 stop6h 01m
United Airlines
Deal found 7/23![United Airlines logo]()
$495
Best flights from Medford to St. LouisDiscover carefully curated flight deals from Medford to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
Discover carefully curated flight deals from Medford to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
This Alaska Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:59 am
MFR
- STL
1 stop7h 45m
Alaska Airlines
Wed 10/287:02 am
STL
- MFR
1 stop7h 44m
Alaska Airlines
Deal found 7/22![Alaska Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/11:28 pm
MFR
- STL
1 stop8h 21m
American Airlines
Fri 12/49:30 am
STL
- MFR
2 stops12h 41m
American Airlines
Deal found 7/25![American Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:08 pm
MFR
- STL
1 stop8h 23m
United Airlines
Sun 9/135:10 am
STL
- MFR
2 stops8h 52m
United Airlines
Deal found 7/23![United Airlines logo]()
$457
This Booking.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:58 pm
MFR
- STL
1 stop17h 23m
Alaska Airlines
Sun 9/207:36 pm
STL
- MFR
1 stop16h 16m
Alaska Airlines
Deal found 7/24![Alaska Airlines logo]()
$452
This Alaska Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:59 am
MFR
- STL
1 stop7h 45m
Alaska Airlines
Tue 10/277:02 am
STL
- MFR
1 stop7h 44m
Alaska Airlines
Deal found 7/26![Alaska Airlines logo]()
$452
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am
MFR
- STL
2 stops8h 37m
United Airlines
Tue 10/2711:15 am
STL
- MFR
2 stops12h 03m
United Airlines
Deal found 7/26![United Airlines logo]()
$545
This Alaska Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:52 pm
MFR
- STL
1 stop23h 18m
Alaska Airlines
Sun 8/237:36 pm
STL
- MFR
1 stop16h 15m
Alaska Airlines
Deal found 7/25![Alaska Airlines logo]()
$507
Last-minute flights from Medford to St. LouisDiscover last-minute flight deals from Medford to St. Louis. Data last updated July 28, 2026 and is based on user searches.
Discover last-minute flight deals from Medford to St. Louis. Data last updated July 28, 2026 and is based on user searches.
This Alaska Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/313:52 pm
MFR
- STL
1 stop22h 45m
Alaska Airlines
Tue 8/45:37 pm
STL
- MFR
1 stop7h 29m
Alaska Airlines
Deal found 7/24![Alaska Airlines logo]()
$523
This Expedia deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:15 am
MFR
- STL
1 stop9h 22m
Alaska Airlines
Thu 8/132:50 pm
STL
- MFR
1 stop11h 14m
Alaska Airlines
Deal found 7/23![Alaska Airlines logo]()
$490
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/52:11 pm
MFR
- STL
2 stops7h 46m
United Airlines
Thu 8/139:00 am
STL
- MFR
1 stop6h 01m
United Airlines
Deal found 7/23![United Airlines logo]()
$495
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
- STL
2 stops19h 45m
Multiple Airlines
Thu 8/137:10 pm
STL
- MFR
1 stop21h 38m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$462
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:35 pm
MFR
- STL
2 stops12h 04m
United Airlines
Wed 8/124:40 pm
STL
- MFR
1 stop6h 28m
United Airlines
Deal found 7/24![United Airlines logo]()
$514
This Alaska Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:35 pm
MFR
- STL
1 stop19h 35m
Alaska Airlines
Sun 8/236:08 pm
STL
- MFR
1 stop6h 41m
Alaska Airlines
Deal found 7/26![Alaska Airlines logo]()
$507
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/221:00 pm
MFR
- STL
1 stop5h 46m
United Airlines
Sat 8/294:40 pm
STL
- MFR
1 stop6h 29m
United Airlines
Deal found 7/25![United Airlines logo]()
$452
This Priceline deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
MFR
- STL
1 stop6h 06m
Alaska Airlines
Sat 8/296:35 am
STL
- MFR
1 stop8h 15m
Alaska Airlines
Deal found 7/25![Alaska Airlines logo]()
$469
One-way flights from Medford to St. LouisSearch for one-way flight options from Medford to St. Louis. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
Search for one-way flight options from Medford to St. Louis. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
This Alaska Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:58 am
MFR
- STL
1 stop10h 59m
Alaska Airlines
Deal found 7/24![Alaska Airlines logo]()
$278
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:07 pm
MFR
- STL
3 stops28h 39m
United Airlines
Deal found 7/23![United Airlines logo]()
$466
Find flight deals from Medford to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $409 (Expedia) |
One-way from | $278 (Alaska Airlines) |
Popular in | December |
Cheapest in | August |
Average price | $616 |
Cheapflights Fare Finder
Customize your flight search to find flights from Medford to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from Medford to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Sat 10/24
5:59 am-3:44 pm
1 stop7h 45m
Lambert-St Louis
Wed 10/28
7:02 am-12:46 pm
1 stop7h 44m
$435
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Tue 9/15
6:58 pm-2:21 pm
1 stop17h 23m
Lambert-St Louis
Sun 9/20
7:36 pm-9:52 am
1 stop16h 16m
$452
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Sat 10/24
5:59 am-3:44 pm
1 stop7h 45m
Lambert-St Louis
Tue 10/27
7:02 am-12:46 pm
1 stop7h 44m
$452
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Tue 12/1
1:28 pm-11:49 pm
1 stop8h 21m
Lambert-St Louis
Fri 12/4
9:30 am-8:11 pm
2 stops12h 41m
$457
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Thu 9/10
1:08 pm-11:31 pm
1 stop8h 23m
Lambert-St Louis
Sun 9/13
5:10 am-12:02 pm
2 stops8h 52m
$457
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Tue 8/18
3:52 pm-5:10 pm
1 stop23h 18m
Lambert-St Louis
Sun 8/23
7:36 pm-9:51 am
1 stop16h 15m
$507
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Sat 10/24
6:00 am-4:37 pm
2 stops8h 37m
Lambert-St Louis
Tue 10/27
11:15 am-9:18 pm
2 stops12h 03m
$545
Cheapest one-way
Quickest one-way
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Fri 8/14
5:58 am-6:57 pm
1 stop10h 59m
$278
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Fri 8/14
2:07 pm-8:46 pm
3 stops28h 39m
$466
Sorted by cheapest first
Compare providers for flights from Medford to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to St. Louis in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Medford-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Medford-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Medford to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Medford with our price prediction graph.
MFR-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated July 28, 2026.
Peruse reviews from past customers who have flown with Delta and United Airlines from Medford to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodAnonymous,Jul 2023
DTW - STL
Entertainment
7.8
Overall
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodAnonymous,Jul 2023
DTW - STL
Entertainment
7.8
Overall
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodAnonymous,Jul 2023
DTW - STL
Related info for your journey
Find useful and relevant information for your journey from Medford to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Farmington
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Medford and St. Louis flights
Browse other Medford and St. Louis flight options. Last updated on July 28, 2026.
Other flights from Medford
Browse through other flights departing from Medford. Flights are based on user searches made on Cheapflights and were last updated on July 28, 2026.
Popular flight searches
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 28, 2026.
Top 2 airlines flying from Medford to St. Louis
Discover the top 2 airlines that operate flights from Medford to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$178 | Average$364 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$224 | Average$513 | FlexibilityNo cancel fee | On-time69% |