$111+ Cheap flights from Santa Ana, CA to St. Louis (SNA - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — STL
Aug 25 — Sep 11
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Santa Ana to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Ana to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Santa Ana to St. LouisExplore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 26, 2026.
Explore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 26, 2026.
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/124:13 pm
SNA
- STL
1 stop24h 02m
Frontier
Wed 8/196:45 pm
STL
- SNA
1 stop19h 46m
Frontier
Deal found 7/22![Frontier logo]()
$256
This CheapOair deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:35 pm
SNA
- STL
1 stop16h 42m
Frontier
Sat 9/128:10 pm
STL
- SNA
1 stop16h 55m
Frontier
Deal found 7/25![Frontier logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:53 pm
SNA
- STL
1 stop20h 12m
Frontier
Wed 8/128:08 pm
STL
- SNA
1 stop16h 20m
Frontier
Deal found 7/22![Frontier logo]()
$266
This Expedia deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/214:50 pm
SNA
- STL
1 stop17h 01m
Frontier
Mon 9/2812:46 pm
STL
- SNA
1 stop6h 49m
Frontier
Deal found 7/23![Frontier logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:07 am
SNA
- STL
1 stop6h 08m
Frontier
Wed 9/3010:35 am
STL
- SNA
2 stops33h 43m
Frontier
Deal found 7/22![Frontier logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:07 am
SNA
- STL
1 stop6h 08m
Frontier
Fri 9/188:10 pm
STL
- SNA
1 stop16h 02m
Frontier
Deal found 7/21![Frontier logo]()
$283
This Expedia deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:50 pm
SNA
- STL
1 stop17h 01m
Frontier
Sun 9/138:10 pm
STL
- SNA
1 stop16h 02m
Frontier
Deal found 7/22![Frontier logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:53 pm
SNA
- STL
2 stops21h 30m
Frontier
Thu 8/138:08 pm
STL
- SNA
1 stop13h 57m
Frontier
Deal found 7/22![Frontier logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:53 pm
SNA
- STL
1 stop20h 12m
Multiple Airlines
Mon 8/178:08 pm
STL
- SNA
2 stops20h 53m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/214:50 pm
SNA
- STL
1 stop17h 01m
Multiple Airlines
Mon 9/288:10 pm
STL
- SNA
2 stops20h 53m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:07 am
SNA
- STL
1 stop6h 08m
Frontier
Sat 9/1910:35 am
STL
- SNA
2 stops33h 43m
Frontier
Deal found 7/21![Frontier logo]()
$305
Best flights from Santa Ana to St. LouisDiscover carefully curated flight deals from Santa Ana to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 26, 2026.
Discover carefully curated flight deals from Santa Ana to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 26, 2026.
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:45 am
SNA
- STL
2 stops8h 55m
Southwest
Thu 10/13:20 pm
STL
- SNA
1 stop8h 05m
Southwest
Deal found 7/25![Southwest logo]()
$380
This Alaska Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:10 pm
SNA
- STL
1 stop25h 00m
Alaska Airlines
Fri 9/256:29 am
STL
- SNA
1 stop9h 20m
Alaska Airlines
Deal found 7/21![Alaska Airlines logo]()
$441
This KAYAK deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:21 pm
SNA
- STL
1 stop6h 53m
American Airlines
Sun 8/236:36 am
STL
- SNA
1 stop8h 54m
American Airlines
Deal found 7/22![American Airlines logo]()
$457
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:00 pm
SNA
- STL
1 stop8h 26m
Delta
Mon 8/178:00 am
STL
- SNA
1 stop6h 05m
Delta
Deal found 7/21![Delta logo]()
$462
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:13 am
SNA
- STL
2 stops11h 47m
United Airlines
Tue 9/81:36 pm
STL
- SNA
1 stop7h 23m
United Airlines
Deal found 7/23![United Airlines logo]()
$480
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:45 am
SNA
- STL
2 stops8h 55m
Southwest
Sat 8/292:25 pm
STL
- SNA
2 stops7h 25m
Southwest
Deal found 7/24![Southwest logo]()
$385
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:30 am
SNA
- STL
2 stops6h 55m
Southwest
Sat 9/262:25 pm
STL
- SNA
2 stops7h 25m
Southwest
Deal found 7/23![Southwest logo]()
$385
This Alaska Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:01 pm
SNA
- STL
1 stop21h 09m
Alaska Airlines
Tue 9/156:29 am
STL
- SNA
2 stops17h 41m
Alaska Airlines
Deal found 7/24![Alaska Airlines logo]()
$459
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:00 am
SNA
- STL
2 stops10h 21m
United Airlines
Tue 10/271:40 pm
STL
- SNA
1 stop5h 53m
United Airlines
Deal found 7/25![United Airlines logo]()
$480
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:55 am
SNA
- STL
2 stops9h 00m
Southwest
Mon 9/282:20 pm
STL
- SNA
2 stops8h 50m
Southwest
Deal found 7/23![Southwest logo]()
$407
This Alaska Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:47 am
SNA
- STL
1 stop15h 12m
Alaska Airlines
Tue 10/277:02 am
STL
- SNA
1 stop9h 21m
Alaska Airlines
Deal found 7/25![Alaska Airlines logo]()
$464
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:30 am
SNA
- STL
2 stops7h 30m
Southwest
Tue 9/12:50 pm
STL
- SNA
2 stops8h 05m
Southwest
Deal found 7/21![Southwest logo]()
$451
Last-minute flights from Santa Ana to St. LouisDiscover last-minute flight deals from Santa Ana to St. Louis. Data last updated July 26, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to St. Louis. Data last updated July 26, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/54:13 pm
SNA
- STL
1 stop24h 02m
Frontier
Wed 8/127:03 pm
STL
- SNA
1 stop19h 28m
Frontier
Deal found 7/23![Frontier logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/73:32 pm
SNA
- STL
1 stop21h 24m
Frontier
Wed 8/128:08 pm
STL
- SNA
1 stop16h 20m
Frontier
Deal found 7/22![Frontier logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:53 pm
SNA
- STL
1 stop20h 12m
Frontier
Wed 8/128:08 pm
STL
- SNA
1 stop16h 20m
Frontier
Deal found 7/22![Frontier logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:53 pm
SNA
- STL
2 stops21h 30m
Frontier
Thu 8/138:08 pm
STL
- SNA
1 stop13h 57m
Frontier
Deal found 7/22![Frontier logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:53 pm
SNA
- STL
1 stop20h 12m
Multiple Airlines
Mon 8/178:08 pm
STL
- SNA
2 stops20h 53m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:53 pm
SNA
- STL
1 stop20h 12m
Frontier
Sat 8/154:57 pm
STL
- SNA
2 stops22h 45m
Frontier
Deal found 7/22![Frontier logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:53 pm
SNA
- STL
2 stops21h 30m
Frontier
Sun 8/168:08 pm
STL
- SNA
1 stop14h 07m
Frontier
Deal found 7/22![Frontier logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:53 pm
SNA
- STL
2 stops21h 30m
Multiple Airlines
Tue 8/188:00 am
STL
- SNA
1 stop9h 01m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$321
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/124:13 pm
SNA
- STL
1 stop24h 02m
Frontier
Wed 8/196:45 pm
STL
- SNA
1 stop19h 46m
Frontier
Deal found 7/22![Frontier logo]()
$256
This CheapOair deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:09 am
SNA
- STL
1 stop8h 04m
Frontier
Fri 8/286:45 pm
STL
- SNA
1 stop22h 03m
Frontier
Deal found 7/24![Frontier logo]()
$325
One-way flights from Santa Ana to St. LouisSearch for one-way flight options from Santa Ana to St. Louis. Find affordable one-way fares based on user searches. Data last updated July 26, 2026.
Search for one-way flight options from Santa Ana to St. Louis. Find affordable one-way fares based on user searches. Data last updated July 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:09 am
SNA
- STL
1 stop8h 04m
Frontier
Deal found 7/25![Frontier logo]()
$111
This Frontier deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:50 pm
SNA
- STL
1 stop6h 27m
Frontier
Deal found 7/23![Frontier logo]()
$128
This Expedia deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:50 pm
SNA
- STL
1 stop17h 01m
Frontier
Deal found 7/23![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/237:53 pm
SNA
- STL
2 stops21h 20m
Frontier
Deal found 7/22![Frontier logo]()
$139
This Frontier deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/124:50 pm
SNA
- STL
1 stop6h 27m
Frontier
Deal found 7/23![Frontier logo]()
$140
This Frontier deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:55 am
SNA
- STL
1 stop8h 28m
Frontier
Deal found 7/25![Frontier logo]()
$174
This Expedia deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:53 pm
SNA
- STL
1 stop20h 22m
Frontier
Deal found 7/22![Frontier logo]()
$180
This CheapOair deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/124:13 pm
SNA
- STL
1 stop24h 02m
Frontier
Deal found 7/25![Frontier logo]()
$186
Find flight deals from Santa Ana to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $256 (CheapOair) |
One-way from | $111 (Kiwi.com) |
Popular in | April |
Cheapest in | October |
Average price | $552 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 26, 2026.
Use the filters below to find and compare flights from Santa Ana to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Mon 9/28
6:45 am-5:40 pm
2 stops8h 55m
Lambert-St Louis
Thu 10/1
3:20 pm-9:25 pm
1 stop8h 05m
$380
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 8/27
6:45 am-5:40 pm
2 stops8h 55m
Lambert-St Louis
Sat 8/29
2:25 pm-7:50 pm
2 stops7h 25m
$385
Quickest round-trip
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Tue 9/22
7:30 am-4:25 pm
2 stops6h 55m
Lambert-St Louis
Sat 9/26
2:25 pm-7:50 pm
2 stops7h 25m
$385
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Mon 9/21
8:55 am-7:55 pm
2 stops9h 00m
Lambert-St Louis
Mon 9/28
2:20 pm-9:10 pm
2 stops8h 50m
$407
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Wed 9/23
2:10 pm-5:10 pm
1 stop25h 00m
Lambert-St Louis
Fri 9/25
6:29 am-1:49 pm
1 stop9h 20m
$441
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Fri 8/28
8:30 am-6:00 pm
2 stops7h 30m
Lambert-St Louis
Tue 9/1
2:50 pm-8:55 pm
2 stops8h 05m
$451
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 8/20
3:21 pm-12:14 am
1 stop6h 53m
Lambert-St Louis
Sun 8/23
6:36 am-1:30 pm
1 stop8h 54m
$457
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 9/10
6:01 pm-5:10 pm
1 stop21h 09m
Lambert-St Louis
Tue 9/15
6:29 am-10:10 pm
2 stops17h 41m
$459
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 8/13
1:00 pm-11:26 pm
1 stop8h 26m
Lambert-St Louis
Mon 8/17
8:00 am-12:05 pm
1 stop6h 05m
$462
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Sat 10/24
6:47 am-11:59 pm
1 stop15h 12m
Lambert-St Louis
Tue 10/27
7:02 am-2:23 pm
1 stop9h 21m
$464
Showing 1-10 of 23 resultsSorted by cheapest first
Compare providers for flights from Santa Ana to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to St. Louis in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana, California-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana, California-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Santa Ana with our price prediction graph.
SNA-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Ana to St. Louis
Prices
More
What is the cheapest month to book a flight from Santa Ana, California to St. Louis?
Currently, October is the cheapest month in which you can book a flight from Santa Ana, California to St. Louis (average of $332). Flying from Santa Ana, California to St. Louis in April is currently the most expensive (average of $566). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santa Ana, California to St. Louis?
Airfare is below average for this route at the moment.
Santa Ana, California to St. Louis flights typically cost between $432 and $543 in August.The cheapest round-trip price found within the last 5 days was $256 on Frontier (Aug 12-Aug 19).
What’s the top layover airport for flights from Santa Ana, California to St. Louis?
Share of 1-stop round-trip flights from Santa Ana, California to St. Louis chosen by Cheapflights users in the past 12 months, using the same layover each way.
Las Vegas (LAS) – chosen by Cheapflights users on 83% of 1-stop itineraries from Santa Ana, California to St. Louis on Cheapflights.
What’s the cheapest layover airport for flights from Santa Ana, California to St. Louis?
Average round-trip fare for 1-stop flights from Santa Ana, California to St. Louis, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Phoenix (PHX) is the most affordable 1-stop option, with an average round-trip price of $541.
What’s the fastest layover option from Santa Ana, California to St. Louis?
Shortest average travel time for 1-stop one-way flights from Santa Ana, California to St. Louis, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Phoenix (PHX) have the shortest average one-way travel time for 1-stop routes: 5h 25m.
Which airport typically offers the quickest layover for flights from Santa Ana, California to St. Louis?
Average layover duration for 1-stop one-way flights from Santa Ana, California to St. Louis, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Phoenix (PHX) offer the fastest connection on this route, with an average layover time of 0h 50m.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated July 26, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Santa Ana to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Santa Ana to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Farmington
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Santa Ana
Popular flights
St. Louis flight routes
Alternative routes for Santa Ana to St. Louis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Santa Ana to St. Louis by cabin class
Find flights from Santa Ana to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Santa Ana and St. Louis flights
Browse other Santa Ana and St. Louis flight options. Last updated on July 26, 2026.
Other flights from Santa Ana
Browse through other flights departing from Santa Ana. Flights are based on user searches made on Cheapflights and were last updated on July 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 26, 2026.
Top 5 airlines flying from Santa Ana to St. Louis
Discover the top 5 airlines that operate flights from Santa Ana to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$129 | Average$218 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$276 | Average$408 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$311 | Average$436 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$316 | Average$519 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$317 | Average$519 | FlexibilityNo cancel fee | On-time71% |