$144+ Cheap flights from Santa Ana, CA to St. Louis (SNA - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — STL
Oct 24 — Oct 311
Round-trip
1 adult, Economy
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Find cheap flights from Santa Ana to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Ana to St. Louis
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Cheapest flights from Santa Ana to St. LouisExplore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/612:33 pm -
1 stop20h 24m
Wed 12/97:54 pm -
1 stop17h 54m
Deal found 9/21![Frontier logo]()
$243
This Cheapflightsfares deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/53:55 pm -
1 stop18h 38m
Mon 11/91:28 pm -
1 stop7h 43m
Deal found 9/20![Frontier logo]()
$274
This Cheapflightsfares deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:08 pm -
1 stop18h 27m
Wed 10/284:18 pm -
1 stop20h 28m
Deal found 9/24![Frontier logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:38 am -
1 stop29h 19m
Thu 10/294:26 pm -
2 stops28h 45m
Deal found 9/23![Frontier logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:30 am -
1 stop27h 03m
Mon 11/91:28 pm -
1 stop7h 43m
Deal found 9/20![Multiple Airlines logo]()
$336
This Travelocity deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:07 am -
1 stop13h 52m
Mon 11/21:28 pm -
1 stop7h 43m
Deal found 9/23![Multiple Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:08 pm -
1 stop18h 27m
Thu 10/294:26 pm -
2 stops28h 45m
Deal found 9/23![Frontier logo]()
$353
Best flights from Santa Ana to St. LouisDiscover carefully curated flight deals from Santa Ana to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from Santa Ana to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2511:38 am -
2 stops27h 20m
Sat 10/317:59 pm -
1 stop17h 47m
Deal found 9/19![Frontier logo]()
$362
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:10 pm -
1 stop7h 00m
Thu 11/198:35 am -
1 stop5h 40m
Deal found 9/23![Southwest logo]()
$399
This Alaska Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:39 am -
1 stop11h 20m
Mon 11/96:00 am -
2 stops15h 09m
Deal found 9/24![Alaska Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:00 pm -
2 stops12h 32m
Mon 11/91:08 pm -
2 stops10h 52m
Deal found 9/23![United Airlines logo]()
$529
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:15 pm -
1 stop8h 20m
Mon 11/94:00 pm -
1 stop7h 05m
Deal found 9/20![Southwest logo]()
$399
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:45 am -
1 stop5h 55m
Fri 11/205:05 am -
1 stop6h 00m
Deal found 9/21![Southwest logo]()
$458
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:45 am -
1 stop6h 35m
Fri 11/275:40 am -
1 stop8h 15m
Deal found 9/24![Southwest logo]()
$473
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:15 pm -
1 stop7h 30m
Tue 10/206:10 pm -
1 stop5h 35m
Deal found 9/21![Southwest logo]()
$503
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:25 pm -
1 stop4h 55m
Wed 10/142:35 pm -
2 stops7h 35m
Deal found 9/22![Southwest logo]()
$519
Last-minute flights from Santa Ana to St. LouisDiscover last-minute flight deals from Santa Ana to St. Louis. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to St. Louis. Data last updated September 24, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:38 am -
1 stop5h 37m
Tue 10/207:02 am -
1 stop10h 54m
Deal found 9/20![Multiple Airlines logo]()
$369
This Travelocity deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:07 am -
1 stop13h 52m
Mon 11/21:28 pm -
1 stop7h 43m
Deal found 9/23![Multiple Airlines logo]()
$343
This Cheapflightsfares deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:08 pm -
1 stop18h 27m
Wed 10/284:18 pm -
1 stop20h 28m
Deal found 9/24![Frontier logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:08 pm -
1 stop18h 27m
Thu 10/294:26 pm -
2 stops28h 45m
Deal found 9/23![Frontier logo]()
$353
This Mytrip deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:08 pm -
2 stops25h 07m
Sat 10/247:42 pm -
2 stops25h 32m
Deal found 9/21![Frontier logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:38 am -
1 stop29h 19m
Thu 10/294:26 pm -
2 stops28h 45m
Deal found 9/23![Frontier logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2511:38 am -
2 stops27h 20m
Sat 10/317:59 pm -
1 stop17h 47m
Deal found 9/19![Frontier logo]()
$362
One-way flights from Santa Ana to St. LouisSearch for one-way flight options from Santa Ana to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
Search for one-way flight options from Santa Ana to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:08 pm -
1 stop18h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Frontier logo]()
$144
This Frontier deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:38 am -
1 stop5h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Frontier logo]()
$156
This Cheapflightsfares deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:38 am -
1 stop5h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Frontier logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:30 am -
1 stop26h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Multiple Airlines logo]()
$171
This Frontier deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:04 pm -
1 stop12h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Frontier logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:35 pm -
2 stops48h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Frontier logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:30 am -
1 stop26h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Multiple Airlines logo]()
$198
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:26 pm -
1 stop8h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![American Airlines logo]()
$200
Find flight deals from Santa Ana to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $243 (Cheapflightsfares) |
One-way from | $144 (Cheapflightsfares) |
Popular in | August |
Cheapest in | October |
Average price | $474 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from Santa Ana to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 10/22
4:08 pm-12:35 pm
1 stop18h 27m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$144
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Mon 10/5
7:30 am-11:32 am
1 stop26h 02m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$171
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 2/25
1:30 pm-11:44 pm
1 stop8h 14m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$200
Quickest round-trip
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 11/19
8:50 am-5:25 pm
2 stops6h 35m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$205
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Sun 10/18
8:59 pm-4:58 pm
2 stops17h 59m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$224
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Sun 10/18
11:38 am-7:15 pm
1 stop29h 37m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$247
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Fri 10/16
2:35 pm-11:42 pm
1 stop7h 07m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$256
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 2/25
3:57 pm-10:20 am
2 stops16h 23m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$263
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Sun 10/18
9:05 pm-8:48 am
1 stop9h 43m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$270
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Wed 10/7
9:17 am-11:59 pm
2 stops12h 42m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$280
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Santa Ana to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to St. Louis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana, California-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana, California-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Santa Ana with our price prediction graph.
SNA-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Ana to St. Louis
Prices
More
What is the cheapest month to book a flight from Santa Ana, California to St. Louis?
Currently, October is the cheapest month in which you can book a flight from Santa Ana, California to St. Louis (average of $396). Flying from Santa Ana, California to St. Louis in August is currently the most expensive (average of $831). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santa Ana, California to St. Louis?
Airfare is below average for this route at the moment.
Santa Ana, California to St. Louis flights typically cost between $364 and $550 in December.The cheapest round-trip price found within the last 5 days was $243 on Frontier (Dec 6-Dec 9).
What’s the top layover airport for flights from Santa Ana, California to St. Louis?
Share of 1-stop round-trip flights from Santa Ana, California to St. Louis chosen by Cheapflights users in the past 12 months, using the same layover each way.
Las Vegas (LAS) – chosen by Cheapflights users on 83% of 1-stop itineraries from Santa Ana, California to St. Louis on Cheapflights.
What’s the cheapest layover airport for flights from Santa Ana, California to St. Louis?
Average round-trip fare for 1-stop flights from Santa Ana, California to St. Louis, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Phoenix (PHX) is the most affordable 1-stop option, with an average round-trip price of $541.
What’s the fastest layover option from Santa Ana, California to St. Louis?
Shortest average travel time for 1-stop one-way flights from Santa Ana, California to St. Louis, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Phoenix (PHX) have the shortest average one-way travel time for 1-stop routes: 5h 25m.
Which airport typically offers the quickest layover for flights from Santa Ana, California to St. Louis?
Average layover duration for 1-stop one-way flights from Santa Ana, California to St. Louis, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Phoenix (PHX) offer the fastest connection on this route, with an average layover time of 0h 50m.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 24, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Santa Ana to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Santa Ana to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Maryland Heights
Collinsville
Edwardsville
Glencoe
Chesterfield
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Santa Ana and St. Louis flights
Browse other Santa Ana and St. Louis flight options. Last updated on September 24, 2026.
Other flights from Santa Ana
Browse through other flights departing from Santa Ana. Flights are based on user searches made on Cheapflights and were last updated on September 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 24, 2026.
Top 4 airlines flying from Santa Ana to St. Louis
Discover the top 4 airlines that operate flights from Santa Ana to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$276 | Average$463 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$328 | Average$519 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$332 | Average$496 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$361 | Average$552 | FlexibilityNo cancel fee | On-time63% |