$80+ Cheap flights from Santa Ana, CA to St. Louis (SNA - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — STL
May 28 — Jun 41
Round-trip
1 adult, Economy
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Find cheap flights from Santa Ana to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Santa Ana to St. LouisExplore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
Explore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
This Expedia deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:14 pm
SNA
- STL
1 stop19h 52m
Frontier
Thu 5/1412:36 pm
STL
- SNA
1 stop25h 43m
Frontier
Deal found 4/23![Frontier logo]()
$206
This CheapOair deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:14 pm
SNA
- STL
1 stop19h 52m
Frontier
Sat 5/236:30 pm
STL
- SNA
1 stop19h 49m
Frontier
Deal found 4/22![Frontier logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:20 pm
SNA
- STL
2 stops20h 28m
Frontier
Wed 6/36:51 pm
STL
- SNA
1 stop19h 28m
Frontier
Deal found 4/23![Frontier logo]()
$226
This CheapOair deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:10 pm
SNA
- STL
1 stop5h 22m
Frontier
Sun 5/39:55 pm
STL
- SNA
1 stop19h 06m
Frontier
Deal found 4/25![Frontier logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:10 pm
SNA
- STL
2 stops21h 13m
Frontier
Sat 6/68:08 pm
STL
- SNA
1 stop15h 01m
Frontier
Deal found 4/27![Frontier logo]()
$254
This CheapOair deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:54 am
SNA
- STL
1 stop7h 29m
Frontier
Sun 5/1012:36 pm
STL
- SNA
1 stop25h 43m
Frontier
Deal found 4/23![Frontier logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:45 am
SNA
- STL
1 stop8h 21m
Multiple Airlines
Wed 6/108:08 pm
STL
- SNA
1 stop15h 21m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:10 pm
SNA
- STL
2 stops21h 13m
Frontier
Wed 6/108:08 pm
STL
- SNA
1 stop15h 21m
Frontier
Deal found 4/27![Frontier logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:10 pm
SNA
- STL
2 stops21h 13m
Frontier
Sun 6/79:06 pm
STL
- SNA
1 stop17h 13m
Frontier
Deal found 4/27![Frontier logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:14 pm
SNA
- STL
1 stop19h 52m
Frontier
Fri 5/154:19 pm
STL
- SNA
2 stops18h 50m
Frontier
Deal found 4/23![Frontier logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:34 pm
SNA
- STL
2 stops39h 21m
Multiple Airlines
Wed 6/107:03 pm
STL
- SNA
1 stop19h 31m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$291
Best flights from Santa Ana to St. LouisDiscover carefully curated flight deals from Santa Ana to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
Discover carefully curated flight deals from Santa Ana to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
This Expedia deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:10 pm
SNA
- STL
1 stop21h 26m
Multiple Airlines
Mon 8/2410:16 am
STL
- SNA
2 stops14h 14m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$383
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/29:52 am
SNA
- STL
1 stop7h 11m
Delta
Tue 6/91:39 pm
STL
- SNA
1 stop7h 27m
Delta
Deal found 4/27![Delta logo]()
$387
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:10 pm
SNA
- STL
2 stops8h 55m
Southwest
Mon 8/242:20 pm
STL
- SNA
2 stops8h 50m
Southwest
Deal found 4/22![Southwest logo]()
$452
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/204:00 pm
SNA
- STL
1 stop5h 57m
United Airlines
Fri 6/265:10 am
STL
- SNA
1 stop5h 57m
United Airlines
Deal found 4/22![United Airlines logo]()
$497
This Alaska Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:09 am
SNA
- STL
1 stop7h 54m
Alaska Airlines
Mon 9/73:00 pm
STL
- SNA
1 stop9h 30m
Alaska Airlines
Deal found 4/26![Alaska Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:51 pm
SNA
- STL
2 stops11h 55m
Delta
Wed 6/32:27 pm
STL
- SNA
2 stops10h 02m
Delta
Deal found 4/23![Delta logo]()
$425
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:50 am
SNA
- STL
2 stops10h 05m
Southwest
Mon 6/13:50 pm
STL
- SNA
2 stops6h 30m
Southwest
Deal found 4/26![Southwest logo]()
$485
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:03 pm
SNA
- STL
1 stop5h 34m
Delta
Thu 8/132:15 pm
STL
- SNA
1 stop5h 58m
Delta
Deal found 4/22![Delta logo]()
$441
This Alaska Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:09 am
SNA
- STL
1 stop7h 54m
Alaska Airlines
Mon 9/73:00 pm
STL
- SNA
1 stop9h 30m
Alaska Airlines
Deal found 4/26![Alaska Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1112:45 pm
SNA
- STL
1 stop8h 36m
Delta
Thu 5/147:00 am
STL
- SNA
1 stop6h 55m
Delta
Deal found 4/24![Delta logo]()
$445
This Alaska Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:45 am
SNA
- STL
1 stop10h 00m
Alaska Airlines
Mon 6/87:41 pm
STL
- SNA
1 stop16h 27m
Alaska Airlines
Deal found 4/22![Alaska Airlines logo]()
$499
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:00 pm
SNA
- STL
1 stop7h 59m
Delta
Mon 6/83:57 pm
STL
- SNA
1 stop8h 31m
Delta
Deal found 4/25![Delta logo]()
$492
Last-minute flights from Santa Ana to St. LouisDiscover last-minute flight deals from Santa Ana to St. Louis. Data last updated April 28, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to St. Louis. Data last updated April 28, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:10 pm
SNA
- STL
1 stop5h 22m
Frontier
Sun 5/39:55 pm
STL
- SNA
1 stop19h 06m
Frontier
Deal found 4/25![Frontier logo]()
$251
This CheapOair deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/32:42 pm
SNA
- STL
1 stop28h 18m
Frontier
Sat 5/98:08 pm
STL
- SNA
1 stop15h 01m
Frontier
Deal found 4/27![Frontier logo]()
$325
This CheapOair deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:54 am
SNA
- STL
1 stop7h 29m
Frontier
Sun 5/1012:36 pm
STL
- SNA
1 stop25h 43m
Frontier
Deal found 4/23![Frontier logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:54 am
SNA
- STL
1 stop7h 29m
Frontier
Wed 5/136:51 pm
STL
- SNA
1 stop19h 28m
Frontier
Deal found 4/24![Frontier logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/94:33 pm
SNA
- STL
2 stops24h 50m
Multiple Airlines
Wed 5/136:51 pm
STL
- SNA
1 stop19h 28m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$323
This Expedia deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:14 pm
SNA
- STL
1 stop19h 52m
Frontier
Thu 5/1412:36 pm
STL
- SNA
1 stop25h 43m
Frontier
Deal found 4/23![Frontier logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:14 pm
SNA
- STL
1 stop19h 52m
Frontier
Fri 5/154:19 pm
STL
- SNA
2 stops18h 50m
Frontier
Deal found 4/23![Frontier logo]()
$284
This CheapOair deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:14 pm
SNA
- STL
1 stop19h 52m
Frontier
Sat 5/236:30 pm
STL
- SNA
1 stop19h 49m
Frontier
Deal found 4/22![Frontier logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/234:33 pm
SNA
- STL
2 stops24h 50m
Multiple Airlines
Tue 5/266:51 pm
STL
- SNA
1 stop22h 47m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:54 am
SNA
- STL
1 stop7h 29m
Frontier
Sat 5/305:27 pm
STL
- SNA
2 stops44h 52m
Frontier
Deal found 4/25![Frontier logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:45 am
SNA
- STL
1 stop8h 21m
Multiple Airlines
Sat 5/308:16 pm
STL
- SNA
2 stops42h 03m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$294
One-way flights from Santa Ana to St. LouisSearch for one-way flight options from Santa Ana to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
Search for one-way flight options from Santa Ana to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
This Frontier deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/169:54 am
SNA
- STL
1 stop7h 29m
Frontier
Deal found 4/25![Frontier logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:10 pm
SNA
- STL
2 stops21h 13m
Frontier
Deal found 4/23![Frontier logo]()
$102
This Frontier deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/309:54 am
SNA
- STL
1 stop7h 29m
Frontier
Deal found 4/26![Frontier logo]()
$105
This CheapOair deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:54 am
SNA
- STL
1 stop7h 29m
Frontier
Deal found 4/23![Frontier logo]()
$126
This CheapOair deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:10 pm
SNA
- STL
1 stop20h 41m
Frontier
Deal found 4/23![Frontier logo]()
$131
This Expedia deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/198:10 pm
SNA
- STL
1 stop15h 56m
Frontier
Deal found 4/24![Frontier logo]()
$134
This CheapOair deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/249:54 am
SNA
- STL
1 stop7h 29m
Frontier
Deal found 4/25![Frontier logo]()
$145
This CheapOair deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/148:10 pm
SNA
- STL
1 stop15h 56m
Frontier
Deal found 4/24![Frontier logo]()
$151
This CheapOair deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:54 am
SNA
- STL
1 stop7h 29m
Frontier
Deal found 4/26![Frontier logo]()
$155
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:23 pm
SNA
- STL
1 stop5h 49m
American Airlines
Deal found 4/23![American Airlines logo]()
$159
Find flight deals from Santa Ana to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $206 (Expedia) |
One-way from | $80 (Frontier) |
Popular in | April |
Cheapest in | October |
Average price | $566 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Santa Ana to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 8/20
8:10 pm-7:36 pm
1 stop21h 26m
Lambert-St Louis
Mon 8/24
10:16 am-10:30 pm
2 stops14h 14m
$383
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Tue 6/2
9:52 am-7:03 pm
1 stop7h 11m
Lambert-St Louis
Tue 6/9
1:39 pm-7:06 pm
1 stop7h 27m
$387
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Mon 6/1
6:51 pm-8:46 am
2 stops11h 55m
Lambert-St Louis
Wed 6/3
2:27 pm-10:29 pm
2 stops10h 02m
$425
Quickest round-trip
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Tue 7/21
5:03 pm-12:37 am
1 stop5h 34m
Lambert-St Louis
Thu 8/13
2:15 pm-6:13 pm
1 stop5h 58m
$441
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Mon 5/11
12:45 pm-11:21 pm
1 stop8h 36m
Lambert-St Louis
Thu 5/14
7:00 am-11:55 am
1 stop6h 55m
$445
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 8/20
12:10 pm-11:05 pm
2 stops8h 55m
Lambert-St Louis
Mon 8/24
2:20 pm-9:10 pm
2 stops8h 50m
$452
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 5/28
8:50 am-8:55 pm
2 stops10h 05m
Lambert-St Louis
Mon 6/1
3:50 pm-8:20 pm
2 stops6h 30m
$485
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 6/4
2:00 pm-11:59 pm
1 stop7h 59m
Lambert-St Louis
Mon 6/8
3:57 pm-10:28 pm
1 stop8h 31m
$492
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Sat 6/20
4:00 pm-11:57 pm
1 stop5h 57m
Lambert-St Louis
Fri 6/26
5:10 am-9:07 am
1 stop5h 57m
$497
Santa AnaSt. Louis
SNA - STL
SNASTL
Santa Ana J. Wayne/Orange Cnty
Sat 9/5
7:09 am-5:03 pm
1 stop7h 54m
Lambert-St Louis
Mon 9/7
3:00 pm-10:30 pm
1 stop9h 30m
$497
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Santa Ana to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to St. Louis in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana, California-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana, California-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Santa Ana with our price prediction graph.
SNA-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Ana to St. Louis
How far ahead should I book a flight from Santa Ana, California to St. Louis?
Booking 63 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santa Ana, California to St. Louis. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Santa Ana, California to St. Louis?
Currently, October is the cheapest month in which you can book a flight from Santa Ana, California to St. Louis (average of $326). Flying from Santa Ana, California to St. Louis in April is currently the most expensive (average of $566). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santa Ana, California to St. Louis?
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated April 28, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Santa Ana to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from Santa Ana to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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Santa Ana and St. Louis flights
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Other flights from Santa Ana
Browse through other flights departing from Santa Ana. Flights are based on user searches made on Cheapflights and were last updated on April 28, 2026.
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 28, 2026.
Top 5 airlines flying from Santa Ana to St. Louis
Discover the top 5 airlines that operate flights from Santa Ana to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$150 | Average$228 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$248 | Average$408 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$278 | Average$411 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$306 | Average$482 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$311 | Average$465 | FlexibilityNo cancel fee | On-time69% |