$323+ Cheap flights from San Diego to Columbia, MO (SAN - COU)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — COU
Oct 14 — Oct 211
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Columbia with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Columbia
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to ColumbiaExplore the most affordable flight options available from San Diego to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
Explore the most affordable flight options available from San Diego to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:50 am -
1 stop8h 25m
Mon 11/166:26 pm -
1 stop7h 28m
Deal found 9/10![American Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:53 pm -
1 stop6h 00m
Tue 11/36:13 am -
1 stop8h 26m
Deal found 9/12![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:21 am -
2 stops9h 37m
Mon 11/163:00 pm -
1 stop9h 40m
Deal found 9/9![United Airlines logo]()
$357
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:46 pm -
1 stop9h 10m
Mon 9/286:32 pm -
1 stop6h 53m
Deal found 9/9![American Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:45 am -
2 stops12h 10m
Mon 9/286:15 am -
1 stop7h 10m
Deal found 9/9![United Airlines logo]()
$418
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:45 pm -
1 stop9h 19m
Mon 11/306:28 pm -
1 stop7h 19m
Deal found 9/13![American Airlines logo]()
$448
Best flights from San Diego to ColumbiaDiscover carefully curated flight deals from San Diego to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
Discover carefully curated flight deals from San Diego to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:50 am -
1 stop8h 25m
Mon 11/166:26 pm -
1 stop7h 28m
Deal found 9/9![American Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:21 am -
2 stops9h 37m
Mon 11/163:00 pm -
1 stop9h 40m
Deal found 9/9![United Airlines logo]()
$357
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:45 am -
2 stops12h 10m
Mon 9/286:15 am -
1 stop7h 10m
Deal found 9/9![United Airlines logo]()
$418
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/62:26 pm -
1 stop6h 56m
Sat 1/93:00 pm -
1 stop9h 37m
Deal found 9/9![United Airlines logo]()
$418
Last-minute flights from San Diego to ColumbiaDiscover last-minute flight deals from San Diego to Columbia. Data last updated September 14, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Columbia. Data last updated September 14, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:46 pm -
1 stop9h 10m
Mon 9/286:32 pm -
1 stop6h 53m
Deal found 9/9![American Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:45 am -
2 stops12h 10m
Mon 9/286:15 am -
1 stop7h 10m
Deal found 9/9![United Airlines logo]()
$418
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:50 am -
1 stop7h 24m
Thu 10/17:44 pm -
1 stop6h 11m
Deal found 9/12![American Airlines logo]()
$866
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:41 pm -
2 stops12h 58m
Thu 10/13:43 pm -
1 stop8h 58m
Deal found 9/12![United Airlines logo]()
$872
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/810:40 pm -
1 stop9h 21m
Sun 10/116:00 am -
1 stop15h 28m
Deal found 9/9![American Airlines logo]()
$806
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:40 pm -
1 stop9h 18m
Sat 10/1712:01 pm -
2 stops8h 16m
Deal found 9/11![American Airlines logo]()
$486
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:15 am -
2 stops12h 18m
Sat 10/173:19 pm -
2 stops11h 12m
Deal found 9/11![United Airlines logo]()
$627
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:53 pm -
1 stop6h 00m
Tue 11/36:13 am -
1 stop8h 26m
Deal found 9/12![American Airlines logo]()
$349
One-way flights from San Diego to ColumbiaSearch for one-way flight options from San Diego to Columbia. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
Search for one-way flight options from San Diego to Columbia. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/810:06 am -
1 stop8h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![American Airlines logo]()
$323
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:55 am -
2 stops10h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![United Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:25 am -
3 stops51h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$363
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:15 am -
2 stops12h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/292:07 pm -
1 stop6h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$423
Find flight deals from San Diego to Columbia
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Columbia (COU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $328 (American Airlines) |
One-way from | $323 (American Airlines) |
Popular in | September |
Cheapest in | February |
Average price | $833 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
Use the filters below to find and compare flights from San Diego to Columbia that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoColumbia
SAN San Diego - COU Columbia Regional
SANCOU
San Diego
Wed 11/11
11:50 am-10:15 pm
1 stop8h 25m
Columbia Regional
Mon 11/16
6:26 pm-11:54 pm
1 stop7h 28m
$328
Quickest round-trip
San DiegoColumbia
SAN San Diego - COU Columbia Regional
SANCOU
San Diego
Sat 10/10
10:55 am-10:55 pm
2 stops10h 00m
Columbia Regional
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$329
San DiegoColumbia
SAN San Diego - COU Columbia Regional
SANCOU
San Diego
Wed 11/11
11:21 am-10:58 pm
2 stops9h 37m
Columbia Regional
Mon 11/16
3:00 pm-10:40 pm
1 stop9h 40m
$357
San DiegoColumbia
SAN San Diego - COU Columbia Regional
SANCOU
San Diego
Sat 10/10
6:25 am-11:39 am
3 stops51h 14m
Columbia Regional
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$363
San DiegoColumbia
SAN San Diego - COU Columbia Regional
SANCOU
San Diego
Thu 9/24
8:45 am-10:55 pm
2 stops12h 10m
Columbia Regional
Mon 9/28
6:15 am-11:25 am
1 stop7h 10m
$418
San DiegoColumbia
SAN San Diego - COU Columbia Regional
SANCOU
San Diego
Wed 1/6
2:26 pm-11:22 pm
1 stop6h 56m
Columbia Regional
Sat 1/9
3:00 pm-10:37 pm
1 stop9h 37m
$418
San DiegoColumbia
SAN San Diego - COU Columbia Regional
SANCOU
San Diego
Tue 9/29
8:45 am-10:55 pm
2 stops12h 10m
Columbia Regional
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$429
San DiegoColumbia
SAN San Diego - COU Columbia Regional
SANCOU
San Diego
Thu 10/8
8:45 am-10:55 pm
3 stops12h 10m
Columbia Regional
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$832
Sorted by cheapest first
Compare providers for flights from San Diego to Columbia
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Columbia in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Columbia, Missouri flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Columbia, Missouri flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Columbia, Missouri flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Columbia, Missouri flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Columbia, Missouri flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Columbia
Have a flexible travel schedule? Discover the best time to fly to Columbia from San Diego with our price prediction graph.
SAN-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Columbia
Get insights into the airlines that provide service to Columbia. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbia. Reviews last updated September 14, 2026.
See what other customers who have flown with American Airlines from San Diego to Columbia have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Boarding
7.4
Comfort
7.2
Food
6.4
Crew
7.9
Overall
7.1
Reviews
1 / 20
2.0
MediocreJeremy,Sep 2025
SAN - PHL
Entertainment
6.8
Boarding
7.4
Comfort
7.2
Food
6.4
Crew
7.9
Overall
7.1
Reviews
1 / 20
2.0
MediocreJeremy,Sep 2025
SAN - PHL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Columbia?
Book flights to Columbia if you plan to visit one of these locationsJefferson City
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Other flights to Columbia
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Complete your trip
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San Diego and Columbia flights
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Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on September 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from San Diego to Columbia
Discover the top airline that operate flights from San Diego to Columbia. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$338 | Average$459 | FlexibilityNo cancel fee | On-time71% |